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61. 发明专利

JP2010530115A Plasma source 有权
公开(公告)号：JP2010530115A
公开(公告)日：2010-09-02
申请号：JP2010507823
申请日：2008-05-02
申请人：マックス―プランク―ゲゼエルシャフトツールフェルデルングデルヴィッセンシャフテンエー.ヴェー
发明人：ステフェス，ベルンド , モルフィル，グレゴール
IPC分类号： H05H1/24 , A61B18/00 , A61L2/14 , H05H1/00 , H05H1/46
CPC分类号： H05H1/24 , H05H1/34 , H05H1/40 , H05H2001/3484 , H05H2240/20 , H05H2245/1225
摘要：本発明はプラズマ源（１）に関し、プラズマ源（１）は、ガス流を搬送する導管（３，４）とプラズマを内部発生させる電離箱（１０）とを備え、電離箱（１０）は、導管（３，４）と連結し、導管（３，４）内のガス流が電離箱（１０）からガス粒子を運び去ることにより、電離箱（１０）内の圧力を減圧する。ガスの電離性は、一般に圧力の上昇とともに低下するため、電離箱内の減圧は、プラズマ発生の効率向上に有利に作用する。従って、低温度を有するガスの中でプラズマを発生させるのが、容易かつ効率的である。
【選択図】図１

62. 发明授权

US12069793B2 Treatment of infectious diseases using non-thermal plasma 有权
公开(公告)号：US12069793B2
公开(公告)日：2024-08-20
申请号：US17409563
申请日：2021-08-23
申请人： CHISCAN HOLDING PTE LTD.
发明人： Bradley N. Eckert , Huan Truong , Bryon K. Eckert
IPC分类号： H05H1/24
CPC分类号： H05H1/2406 , H05H1/47 , H05H2240/20
摘要： An array of non-thermal plasma emitters is controlled to emit plasma based on application of an electric current at desired frequencies and a controlled power level. A power supply for an array controller includes a transformer that operates at the resonant frequency of the combined capacitance of the array and the cable connecting the array to the power supply. The power into the array is monitored by the controller and can be adjusted by the user. The controller monitors reflected power characteristics, such as harmonics of the alternating current, to determine initiation voltage of the plasma and/or resonant frequency plasma emitters. The array of non-thermal plasma emitters may be used in therapeutic, diagnostic, and/or medical sanitization applications, including for treatment of infectious diseases using the disclosed protocols.

63. 发明公开

US20240189012A1 PLASMA GAS GENERATOR 审中-公开
公开(公告)号：US20240189012A1
公开(公告)日：2024-06-13
申请号：US18223924
申请日：2023-07-19
申请人： Thomas J. SHEPERAK
发明人： Thomas J. SHEPERAK
IPC分类号： A61B18/04 , A61L2/00 , A61N1/44 , A61N5/10 , G21K1/093 , H05H1/46
CPC分类号： A61B18/042 , A61L2/007 , A61N1/44 , A61N5/10 , G21K1/093 , H05H1/46 , H05H1/4645 , A61N2005/1089 , H05H1/466 , H05H2240/20 , H05H2242/26 , H05H2245/34
摘要： A method of generating an output gas, comprising plasmatizing an input gas with RF power propagating from a tip of an electrode to form an annular plasma sheath constrained by a tube with said RF power propagating within said annular plasma sheath; and forming said output gas as said annular plasma sheath propagates away from said tip of said electrode.

64. 发明申请

US20180242577A1 METHODS OF AND SYSTEM FOR GENERATING ANTIMICROBIAL WIPES 审中-公开
公开(公告)号：US20180242577A1
公开(公告)日：2018-08-30
申请号：US15753565
申请日：2016-08-30
申请人： EP Technologies LLC
发明人： Tsung-Chan Tsai , Jeffrey S. Louis , Daphne Pappas Antonakas , Sameer Kalghatgi , Robert L. Gray
IPC分类号： A01N25/34 , H05H1/24
CPC分类号： A01N25/34 , A01N25/00 , A61L2/0011 , A61L2/0088 , A61L2/14 , A61L2/18 , A61L2202/11 , A61L2202/14 , A61L2202/15 , A61L2202/17 , C02F1/4608 , C02F2303/04 , C02F2305/023 , H05H1/24 , H05H1/2406 , H05H2001/2412 , H05H2240/20 , H05H2245/1225 , A01N59/00 , A01N61/00
摘要： Exemplary methods of and system for generating an antimicrobial wipe to clean and disinfect a surface contaminated with bacteria, viruses, spores, fungi, or combinations thereof. In some embodiments, the method includes applying non-thermal plasma to a moistened wipe to activate a liquid in the wipe. In some embodiments, the method includes applying non-thermal plasma to a liquid and then applying the activated liquid to a wipe. In one embodiment of a system for generating an antimicrobial wipe the system includes a housing having an opening; a supply of wipes disposed within the housing; a non-thermal plasma generator disposed within the housing; a power supply electrically coupled to the non-thermal plasma generator; and a feed system disposed within the housing, wherein the feed system moves one or more wipes from the supply of wipes past the plasma generator and out of the opening. As the feed system moves the wipes past the plasma generator, the plasma generator applies non-thermal plasma to the wipes.

65. 发明申请

US20170156200A1 Cold Plasma Treatment Devices and Associated Methods 审中-公开
公开(公告)号：US20170156200A1
公开(公告)日：2017-06-01
申请号：US15431208
申请日：2017-02-13
申请人： Plasmology4, Inc.
发明人： Gregory A. Watson , Robert M. Hummel , Marc C. Jacofsky , David J. Jacofsky
IPC分类号： H05H1/46 , A61N1/44 , A61L2/14 , H05H1/24 , H01J37/32
CPC分类号： H05H1/46 , A61L2/00 , A61L2/0011 , A61L2/0094 , A61L2/14 , A61L2202/11 , A61M15/02 , A61M16/06 , A61M16/12 , A61M2202/0208 , A61M2202/025 , A61N1/40 , A61N1/44 , H01J37/321 , H01J37/32348 , H01J37/3244 , H01J37/3266 , H05H1/2406 , H05H2001/2412 , H05H2001/466 , H05H2001/4682 , H05H2240/20 , H05H2245/1225 , H05H2277/10
摘要： A compact cold plasma device for generating cold plasma having temperatures in the range 65 to 120 degrees Fahrenheit. The compact cold plasma device has a magnet-free configuration and an induction-grid-free configuration. An additional configuration uses an induction grid in place of the input electrode to generate the cold plasma. A high voltage power supply is provided that includes a controllable switch to release energy from a capacitor bank to a dual resonance RF transformer. A controller adjusts the energy input to the capacitor bank, as well as the trigger to the controllable switch.

66. 发明申请

US20160338755A1 NON-THERMAL PLASMA 审中-公开
标题翻译：非热等离子体
公开(公告)号：US20160338755A1
公开(公告)日：2016-11-24
申请号：US15112699
申请日：2015-01-22
申请人： LINDE AKTIENGESLLSCHAFT
发明人： Thomas Bickford Holbeche , Rodney Stewart Mason
IPC分类号： A61B18/04 , H05H1/24
CPC分类号： A61B18/042 , A45D19/02 , A45D2200/20 , A61B2018/00029 , A61B2018/00321 , A61B2018/00452 , A61B2018/00583 , A61B2018/00744 , A61B2018/00863 , H05H1/2406 , H05H2001/2412 , H05H2240/20 , H05H2245/122
摘要： A plasma-generation device for applying plasma to a human body, having a reservoir containing a gas, a plasma zone in fluid connection with the reservoir, and means for generating a plasma by electrical discharge in the plasma zone. The gas has a composition of 92% to 99.9% Argon and 0.1% to 8% Krypton; or 95% to 99.5% Argon and 0.5% to 5% Hydrogen; or 92% to 99.5% Argon and 0.5% to 8% Nitrous Oxide.
摘要翻译：一种用于将等离子体施加到人体上的等离子体生成装置，具有包含气体的储存器，与储存器流体连接的等离子体区域，以及用于通过等离子体区域中的放电产生等离子体的装置。该气体具有92％至99.9％的氩气和0.1％至8％的氪气的组成; 或95％至99.5％的氩气和0.5％至5％的氢气; 或92％至99.5％的氩气和0.5％至8％的一氧化二氮。

67. 发明授权

US09387269B2 Cold plasma jet hand sanitizer 有权
标题翻译：冷等离子喷枪洗手液
公开(公告)号：US09387269B2
公开(公告)日：2016-07-12
申请号：US13802063
申请日：2013-03-13
申请人： Bovie Medical Corporation
发明人： Gregory A. Konesky
IPC分类号： A61L2/14 , B01J19/08 , H05H1/46 , A61B18/00 , A61L2/00 , H05H1/48
CPC分类号： H01J37/32128 , A61B2018/00583 , A61L2/0011 , A61L2/14 , A61L2202/11 , B01J19/088 , B01J2219/0809 , B01J2219/0828 , B01J2219/0896 , H01J37/244 , H01J37/32174 , H01J37/32449 , H01J37/32513 , H01J37/32568 , H05H1/46 , H05H2001/466 , H05H2001/4682 , H05H2001/483 , H05H2240/10 , H05H2240/20 , H05H2245/1225
摘要： A cold plasma jet hand sanitizer and method of use are provided. A pair of opposing two-dimensional arrays of atmospheric pressure cold plasma jets is used to create a sterilizing volume. Any object placed into that volume will have its surface sterilized. The opposing arrays of plasma jets are operated electrically 180 degrees out of phase so that the opposing arrays of plasma jets essentially fire into each other in the absence of an intervening object, or directly impinge on the surface of an intervening object.
摘要翻译：提供冷等离子喷射洗手液和使用方法。使用一对相对的二维大气压冷等离子体喷射阵列来产生灭菌体积。放置在该体积中的任何物体将其表面消毒。等离子体射流的相对阵列电动180度异相操作，使得相对的等离子体射流阵列在不存在中间物体的情况下基本上彼此发射，或者直接撞击在居间物体的表面上。

68. 发明授权

US09308285B2 Gas plasma disinfection and sterilisation apparatus 有权
标题翻译：气体等离子消毒灭菌器具
公开(公告)号：US09308285B2
公开(公告)日：2016-04-12
申请号：US14360593
申请日：2012-11-14
申请人： CREO MEDICAL LIMITED
发明人： Christopher Paul Hancock , Steven Morris
IPC分类号： A61L2/14 , H05H1/46
CPC分类号： A61L2/14 , H05H1/46 , H05H2001/463 , H05H2240/20 , H05H2245/1225
摘要： A sterilization or disinfecting system in which non-thermal plasma is generated in pulses, in which pulses of microwave frequency energy are used to sustain each plasma pulse, and a detectable characteristic of each pulse of microwave energy is used to trigger a radiofrequency strike pulse which strikes the plasma. The system includes a strike signal generation circuit arranged to condition and/or process the signal from the microwave signal coupler to form a control signal based on the detectable characteristic, which may be the rising edge or amplitude of the pulse.
摘要翻译：一种消毒或消毒系统，其中以脉冲形式产生非热等离子体，其中使用微波频率能量的脉冲来维持每个等离子体脉冲，并且使用微波能量的每个脉冲的可检测特性来触发射频冲击脉冲，撞击等离子体该系统包括一个撞击信号发生电路，其布置成基于可检测特性（其可以是脉冲的上升沿或幅度）来调节和/或处理来自微波信号耦合器的信号以形成控制信号。

69. 发明申请

US20160095644A1 Cold Plasma Scalpel 审中-公开
标题翻译：冷等离子体手术
公开(公告)号：US20160095644A1
公开(公告)日：2016-04-07
申请号：US14876358
申请日：2015-10-06
申请人： U.S. Patent Innovations, LLC
发明人： Jerome Canady , Taisen Zhuang
IPC分类号： A61B18/04
CPC分类号： A61B18/042 , A61B2018/00083 , A61B2018/00178 , A61B2018/00601 , H05H1/46 , H05H2001/245 , H05H2240/20 , H05H2245/122
摘要： An attachment for an electrosurgical hand piece. The attachment comprises a probe assembly having an elongated tube having a proximal end and a distal end, and an electrode. The electrode has at a proximal end a conductive connector, which has a proximal end, a distal end and a channel extending through the conductive connector. The conductive connector may be comprised of a nickel plated brass alloy. The electrode further has a conductive wire extending from said distal end of said conductive connector, said conductive wire being connected to said distal end of said conductive connector adjacent to said channel in said conductive connector. The conductive wire extends substantially along the length of the elongated tube and may or may not extend out of the end of the tube.
摘要翻译：电外科手部附件。附件包括具有具有近端和远端的细长管和电极的探针组件。电极在近端具有导电连接器，导电连接器具有近端，远端和延伸穿过导电连接器的通道。导电连接器可以由镀镍的黄铜合金构成。所述电极还具有从所述导电连接器的所述远端延伸的导线，所述导线连接到所述导电连接器的所述远端，邻近所述导电连接器中的所述通道。导线基本上沿着细长管的长度延伸，并且可以或不延伸出管的端部。

70. 发明申请

US20150151135A1 TRANSDERMAL DELIVERY OF DNA VACCINES USING NON-THERMAL PLASMA 审中-公开
标题翻译：使用非热等离子体转染DNA疫苗
公开(公告)号：US20150151135A1
公开(公告)日：2015-06-04
申请号：US14560343
申请日：2014-12-04
申请人： Sameer Kalghatgi , Daphne Pappas Antonakas , Tsung-Chan Tsai , Robert L. Gray
发明人： Sameer Kalghatgi , Daphne Pappas Antonakas , Tsung-Chan Tsai , Robert L. Gray
IPC分类号： A61N1/44 , A61N5/06 , A61K39/00 , A61M37/00
CPC分类号： A61N1/44 , A61K48/00 , A61M37/00 , A61M2037/0007 , A61N1/0412 , A61N1/327 , A61N5/0616 , C12N15/87 , H05H1/2406 , H05H2001/481 , H05H2240/10 , H05H2240/20 , H05H2245/122
摘要： Exemplary systems and methods of delivering DNA vaccines are disclosed herein. An exemplary methodology of delivering DNA vaccines includes providing a plasma generator for applying plasma to a treatment area for a sufficient period of time to open one or more pores. Applying a topical DNA vaccine to the treatment area and waiting for a period of time to allow the DNA vaccine to travel through the one or more pores. The exemplary methodology further includes applying plasma to the treatment area at a setting sufficient to cause intracellular uptake of the DNA vaccine.
摘要翻译：本文公开了递送DNA疫苗的示例性系统和方法。提供DNA疫苗的示例性方法包括提供等离子体发生器，用于将等离子体施加到处理区域足够的时间以打开一个或多个孔。将局部DNA疫苗应用于治疗区域，并等待一段时间以允许DNA疫苗穿过一个或多个孔。示例性方法还包括以足以引起细胞内摄取DNA疫苗的设置将血浆施用于治疗区域。

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