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61. 发明授权

US06599231B1 Loading clip for radioisotope seeds 失效
标题翻译：加载放射性同位素种子的夹子
公开(公告)号：US06599231B1
公开(公告)日：2003-07-29
申请号：US09658636
申请日：2000-09-11
申请人： Daniel M. Elliott , George M. Hoedeman , John J. Berkey , Jonathan D. Elliott
发明人： Daniel M. Elliott , George M. Hoedeman , John J. Berkey , Jonathan D. Elliott
IPC分类号： A61M3612
CPC分类号： A61M37/0069 , A61N5/1007 , A61N5/1027 , A61N2005/1009 , A61N2005/101 , A61N2005/1011
摘要： A loading clip for low dose radioisotope seeds has a body having a channel defined therein. The channel has a cavity adapted for receiving a radioisotope seed at a distal end. A slider member slidably positionable within the channel has a spring biased tooth at a distal end. A constant force spring member is slidably positioned within the channel between the slider member and the body. Radioisotope seeds are magazined into the loading clip biased against the constant force spring member by operation of the slider member extending the tooth over the cavity and retracting a radioisotope seed in the cavity into the channel. In one embodiment, radioisotope seeds are magazined into the loading clip that is then used to load an automated seed cartridge. In this embodiment, the loading clip has structure for mating with an aperture in the automated seed cartridge so as to introduce radioisotope seeds into the seed cartridge one at a time. Preferably, the loading clip is provided with a machine readable storage medium accessible via an electrical connector that stores indicia representing at least information about the radioisotope seeds located in the loading clip.
摘要翻译：用于低剂量放射性同位素种子的加载夹具具有限定在其中的通道的主体。通道具有适于在远端接收放射性同位素种子的空腔。可滑动地定位在通道内的滑块构件在远端具有弹簧偏置的齿。恒力弹簧构件可滑动地定位在滑动构件和主体之间的通道内。放射性同位素种子通过使牙齿在空腔上延伸并将空腔中的放射性同位素种子收回到通道中的滑动构件的操作而被杂入到加载夹中偏压恒定力弹簧构件。在一个实施方案中，将放射性同位素种子杂交到装载夹中，然后将其用于装载自动种子盒。在该实施例中，装载夹具有用于与自动种子盒中的孔配合的结构，以便将放射性同位素种子一次一个地插入种子盒中。优选地，装载夹具具有可通过电连接器访问的机器可读存储介质，该电连接器存储表示至少关于位于加载夹中的放射性同位素种子的信息的标记。

62. 发明授权

US06537192B1 Automated radioisotope seed loader system for implant needles 有权
标题翻译：用于植入针的自动放射性同位素种子装载机系统
公开(公告)号：US06537192B1
公开(公告)日：2003-03-25
申请号：US09587624
申请日：2000-06-05
申请人： Daniel M. Elliott , George M. Hoedeman , John J. Berkey , Jonathan D. Elliott
发明人： Daniel M. Elliott , George M. Hoedeman , John J. Berkey , Jonathan D. Elliott
IPC分类号： A61M3600
CPC分类号： A61M37/0069 , A61N5/1007 , A61N5/1027 , A61N5/103 , A61N2005/1008 , A61N2005/1009 , A61N2005/1011
摘要： An automated system for loading low dose radioisotope seeds into a plurality of implant needles includes a loading station into which a replaceable cartridge may be positioned. The cartridge is preloaded with a plurality of radioisotope seeds and a plurality of spacers. The cartridge has at least one aperture and preferably the radioisotope seeds and spacers are loaded around the periphery of a rotatable drum within the cartridge. The loading station has a cartridge receiving structure and an automated motion control system. When the cartridge is positioned in the cartridge receiving structure, the automated motion control system preferably drives a pair of stepper motors within the cartridge, one for rotating the rotatable drum and one for sliding a pushrod to selectively eject radioisotope seeds and spacers from the cartridge into each of a plurality of implant needles positioned so as to receive the radioisotopes seeds and spacers within the implant needle. In one embodiment, the implant needles are positioned tip first into the loading station, and once a predetermined arrangement of radioisotope seeds and spacers are loaded into the implant needle, a plug is positioned in the tip of the implant needle. Preferably, the automated system includes a computer processor having a touch screen user interface that is connected to and directs the operation of the automated motion control system to load the plurality of implant needles in accordance with a predetermined dose plan.
摘要翻译：用于将低剂量放射性同位素种子装载到多个植入针中的自动化系统包括装载站，可替换的盒可定位在该装载站中。盒预先装载有多个放射性同位素种子和多个间隔物。盒具有至少一个孔，并且优选地，放射性同位素种子和间隔物被装载在盒内的可旋转滚筒的周边周围。装载站具有盒式接收结构和自动运动控制系统。当墨盒定位在墨盒接收结构中时，自动运动控制系统优选地驱动墨盒内的一对步进马达，一个用于旋转可旋转滚筒，一个用于滑动推杆以选择性地将放射性同位素种子和间隔物从墨盒中排出多个植入针中的每一个定位成在植入针内容纳放射性同位素种子和间隔物。在一个实施例中，将注射针首先定位到装载站中，并且一旦将放射性同位素种子和间隔物的预定布置装载到植入针中，则将插头定位在植入针的尖端中。优选地，自动化系统包括具有触摸屏用户界面的计算机处理器，该触摸屏用户界面连接到并指导自动运动控制系统的操作，以根据预定剂量计划加载多个植入针。

63. 发明申请

US20030018232A1 Automated implantation system for radioisotope seeds 失效
标题翻译：放射性同位素种子自动植入系统
公开(公告)号：US20030018232A1
公开(公告)日：2003-01-23
申请号：US10010968
申请日：2001-11-13
申请人： Mentor Corporation
发明人： Daniel M. Elliott , John J. Berkey , George M. Hoedeman
IPC分类号： A61N005/00
CPC分类号： A61M37/0069 , A61N5/1007 , A61N5/1027 , A61N5/103 , A61N2005/1008 , A61N2005/1009 , A61N2005/101 , A61N2005/1011
摘要： An automated implantation system assists the implantation of low dose radioisotope seeds in a patient as part of a brachytherapy procedure. A Z-axis automated motion control system and an X-Y axis automated motion control system control a needle assembly. The X-Y axis automated motion control system positions an insertion axis of the needle assembly relative to the patient. The Z-axis automated motion control system selectively moves the needle assembly along the insertion axis to implant at least one radioisotope seed. This process is repeated for a plurality of locations on a base plane perpendicular to the insertion axis. Preferably, the radioisotope seeds are contained in a replaceable cartridge and the needle assembly is also replaceable.
摘要翻译：自动植入系统有助于在患者中植入低剂量放射性同位素种子作为近距离放射治疗程序的一部分。 Z轴自动运动控制系统和X-Y轴自动运动控制系统控制针组件。 X-Y轴自动运动控制系统定位针组件相对于患者的插入轴线。 Z轴自动运动控制系统选择性地沿着插入轴移动针组件以植入至少一种放射性同位素种子。对垂直于插入轴的基本平面上的多个位置重复该过程。优选地，放射性同位素种子被包含在可更换的盒中，并且针组件也是可替换的。

64. 发明授权

US4759345A Radiation shielded seed loader for hand implanter hypodermic needles apparatus and method 失效
标题翻译：用于手持式皮下注射针的放射屏蔽种子装载机和方法
公开(公告)号：US4759345A
公开(公告)日：1988-07-26
申请号：US12626
申请日：1987-02-09
申请人： Vitthalbhai D. Mistry
发明人： Vitthalbhai D. Mistry
IPC分类号： A61M36/12 , A61N5/10 , A61N5/01
CPC分类号： A61M37/0069 , A61N2005/1009 , A61N5/1027
摘要： A safe radiation shielded seed loader for hand implanter hypodermic needles with removable seed loading disk. The removable seed loading disk enhances the ability to quickly and safely load radioactive seeds into hypodermic needles. As a result, the loading process is greatly expedited and a substantial reduction of the radiation exposure time to hands, fingers and eyes of the person loading the seeds is accomplished. Once loaded, a spacer-key prevents obturators from pressing the loaded seeds, now carried in a shielded container, out of the needles until use. A removable carrying handle with lifting arms and a cover plate with a recessed area to accommodate the heads of the obturators is provided. As a result, the easily and quickly loaded device may be safely transported to the implantation site without fear of radiation exposure or damage to the needles themselves.
摘要翻译：一种安全的辐射屏蔽种子装载机，用于手动植入式皮下注射针，带有可移除的种子加载盘。可移动的种子加载盘增强了将放射性种子快速，安全地装入皮下注射针的能力。结果，加载过程大大加快，并且完成了装载种子的人的手，手指和眼睛的辐射暴露时间的显着减少。一旦加载，间隔件键可以防止堵塞器将现在装在屏蔽的容器中的装载的种子从针中挤出，直到使用。提供具有提升臂的可拆卸携带手柄和具有用于容纳封闭器头部的凹陷区域的盖板。因此，容易且快速加载的装置可以被安全地运送到植入位置，而不用担心辐射暴露或针本身的损坏。

65. 发明授权

US3787699A Rotary drum for storing radio-active objects 失效
标题翻译：用于存储无线电活动目标的旋转鼓
公开(公告)号：US3787699A
公开(公告)日：1974-01-22
申请号：US3787699D
申请日：1971-06-24
申请人： ATOMIC ENERGY COMMISSION
发明人： MENACHEM S , KIS I , ROSENTAL N
IPC分类号： A61N5/10 , G21F5/008 , G21F5/015 , G21K5/08 , G21H5/00
CPC分类号： G21K5/08 , A61N2005/1009 , G21F5/008 , G21F5/015
摘要： Apparatus for the storage of radio-active objects, such as, for example, radio-active needles or the like, comprising a cylindrical drum mounted for rotation about its axis within a cylindrical casing, a first plurality (m) of axially spaced tiers of radially directed cavities formed in said drum so as to join a second plurality (n) of radially spaced apart columns of cavities, an elongated opening formed in the casing, means for rotatably displacing the drum so as successively to bring successive cavity columns opposite said opening and a first plurality (m) of individual closure means associated with said opening and respectively adapted to close the cavities otherwise exposed by the opening.
摘要翻译：用于存储无线电活动物体（例如无线电针等）的装置包括安装成用于在圆柱形壳体内围绕其轴线旋转的圆柱形鼓，第一多个（m）轴向间隔的层形成在所述滚筒中的径向定向的空腔，以便连接形成在壳体中的细长开口的第二多个（n）径向隔开的空腔列;用于可旋转地移动滚筒以便连续地使连续的空腔列与所述开口相对的装置以及与所述开口相关联并且分别适于闭合由开口暴露的空腔的单个闭合装置的第一多个（m）。

66. 发明公开

EP2925407A1 DEVICE FOR PERCUTANEOUS INTERSTITIAL BRACHYTHERAPY 有权
标题翻译：设备经皮间植入
公开(公告)号：EP2925407A1
公开(公告)日：2015-10-07
申请号：EP12824859.8
申请日：2012-11-28
申请人： Raus, Laura
发明人： CAROLI, Fabrizio , RAUS, Laura
IPC分类号： A61N5/10
CPC分类号： A61N5/1007 , A61B90/39 , A61B2090/3966 , A61N5/1015 , A61N5/1027 , A61N5/1048 , A61N2005/1009 , A61N2005/101 , A61N2005/1024 , A61N2005/1074 , A61N2005/1094
摘要： A portable device (1) for the insertion of radioactive seeds in percutaneous interstitial brachytherapy applications, comprising: - an elongated main body (2) in the form of a handpiece; - a shielded container (3) of radioactive seeds, received within said main body (2) and having a rotating drum (30) suitable, in use, to release one or more radioactive seeds at a time from the container (3); - means (4) for driving said rotating drum (30), activatable by an operator and based on lever mechanisms (41, 42) and gears (43, 44); and - means (7) for introducing one or more radioactive seeds in a body site of interest, comprising a substantially wire-shaped pusher (70), the overall arrangement being such that, in use, the pusher (70) urges the radioactive seed(s) released from said rotating drum (30) through a cannula unit (10), the latter connected, at one first proximal longitudinal end thereof, to said main body (2) and percutaneously inserted so that a distal longitudinal end thereof be arranged in the body site (Fig. 1).

67. 发明公开

EP2605820A2 TETHERED AND/OR VISUALLY CODED BRACHYTHERAPY DEVICES AND RELATED METHODS 审中-公开
标题翻译： GEBUNDENE UND / ODER VISUELL KODIERTE BRACHYTHERAPIEVORRICHTUNG UND HERSTELLUNGSVERFAHREN
公开(公告)号：EP2605820A2
公开(公告)日：2013-06-26
申请号：EP11818541.2
申请日：2011-08-03
申请人： Wake Forest University Health Sciences
发明人： KADER, Andrew Karim , FRIED, Daniel B.
IPC分类号： A61M36/04 , A61M36/06 , A61N5/00 , A61B17/34 , A61M5/145
CPC分类号： A61N5/1007 , A61B17/3468 , A61B90/92 , A61B2017/00274 , A61B2017/3411 , A61B2090/3987 , A61N5/1001 , A61N2005/1009 , A61N2005/1012 , A61N2005/1024 , Y10T29/49826
摘要： Bracytherapy devices include a respective tether attached to a proximal end portion of the strands. The tether can be color-coded to match a color associated with the corresponding strand.
摘要翻译： Bracytherapy装置包括连接到股线的近端部分的相应系绳。系绳可以进行颜色编码以匹配与相应链条相关联的颜色。

68. 发明授权

EP2125098B1 BRACHYTHERAPY ELEMENT TRANSFER SYSTEM 有权
标题翻译：传输系统的短程治疗元素
公开(公告)号：EP2125098B1
公开(公告)日：2012-09-26
申请号：EP08754831.9
申请日：2008-02-28
申请人： C.R.Bard, Inc.
发明人： DROBNIK, Christopher , DROBNIK, Michael , WATSON, Breese
IPC分类号： A61N5/10 , A61M36/04
CPC分类号： A61N5/1027 , A61N2005/1009 , A61N2005/1023

69. 发明公开

EP2359904A1 Magazin für Kettenbestandteile einer Kette mit radioaktiven Strahlenquellen sowie ein System aus einem Kettenbestandteil und einem Magazin 有权
标题翻译：杂志的放射性辐射源链和链部件的系统和杂志的链组分
公开(公告)号：EP2359904A1
公开(公告)日：2011-08-24
申请号：EP10153450.1
申请日：2010-02-12
申请人： Eckert & Ziegler Bebig GmbH
发明人： Hentrich, Dr. Axel , Lederer, Dipl.-Ing. Christoph
IPC分类号： A61N5/10
CPC分类号： A61N5/1007 , A61N2005/1009 , A61N2005/101 , C07C209/10 , C07C2603/97 , H01L51/0059 , C07C211/61
摘要： Die Erfindung betrifft ein Magazin (1) für Kettenbestandteile einer Kette mit radioaktiven Strahlenquellen (19), welches ein Gehäuse (7) umfasst sowie ein erstes Mittel zur Aufnahme von Kettenbestandteilen (2), das drehbar in dem Gehäuse (7) gelagert ist und Vertiefungen (6) zur Aufnahme von Kettenbestandteilen aufweist, eine Spannfeder (3) zum Vortrieb des Mittels zur Aufnahme von Kettenbestandteilen (2), einen Zahnkranz (13), der drehbar mit dem Mittel zur Aufnahme von Kettenbestandteilen (2) gekoppelt in dem Gehäuse (7) angeordnet ist, und einen Auswurf (10) zum Auswurf der Strahlenquellen (26). Ferner umfasst das Magazin einen Auswerferhebel (4), der rotatorisch so in dem Gehäuse gelagert ist, dass er in einer ersten Stellung in den Zahnkranz (13) eingreifbar ausgebildet ist und in einer zweiten Stellung den Auswurf (10) blockierbar ausgebildet ist.
摘要翻译：该杂志（1）具有用于驱动所述种子库拉簧确实接收链组件（10），其安装在壳体中的链轮（7）以枢转的方式并牢固地联接种子库，并以喷射器用于喷射辐射源，安装在外壳中的枢转方式的弹射杆，在寻求一种方式“”在一个第一位置，排出杆接合所述链轮被配置为在第二中位置的块喷射器。因此独立claimsoft包括用于链组分体系。

70. 发明公开

EP2125098A2 BRACHYTHERAPY ELEMENT TRANSFER SYSTEM 有权
标题翻译：传输系统的短程治疗元素
公开(公告)号：EP2125098A2
公开(公告)日：2009-12-02
申请号：EP08754831.9
申请日：2008-02-28
申请人： C.R.Bard, Inc.
发明人： DROBNIK, Christopher , DROBNIK, Michael , WATSON, Breese
IPC分类号： A61M36/04
CPC分类号： A61N5/1027 , A61N2005/1009 , A61N2005/1023
摘要： Disclosed herein is a system for transferring brachytherapy elements to a needle, such as seeds, connectors, spacers, and strands. The system comprises a transfer device and, optionally, a stylet and a rack configured to hold one or more transfer devices.

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