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61. 发明授权

US06604908B1 Methods and systems for pulsed delivery of fluids from a pump 有权
标题翻译：用于从泵脉冲输送流体的方法和系统
公开(公告)号：US06604908B1
公开(公告)日：2003-08-12
申请号：US09357646
申请日：1999-07-20
申请人： Robert J. Bryant , Lawrence B. Gray , Geoff P. Spencer
发明人： Robert J. Bryant , Lawrence B. Gray , Geoff P. Spencer
IPC分类号： F04B4900
CPC分类号： A61M1/3696 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/1062 , A61M1/1086 , A61M1/1087 , A61M1/1096 , A61M1/367 , A61M5/14224 , A61M5/14593 , A61M5/16809 , A61M5/16813 , A61M5/16859 , A61M5/365 , A61M39/22 , A61M39/281 , A61M2205/053 , A61M2205/12 , A61M2205/123 , A61M2205/125 , A61M2205/128 , A61M2205/14 , A61M2205/17 , A61M2205/3334 , A61M2205/3396 , A61M2205/50 , F04B13/00 , F04B43/0081 , F04B43/067 , F04B43/073 , F04B43/107 , F04B43/113 , F04B49/065 , F04B49/24 , F04B53/06
摘要： A system is disclosed for pumping fluids at desired average flow rates by applying a predetermined force to a pump chamber and pulsing an outlet valve of the pump chamber to deliver a fluid therefrom. In some embodiments, pump chambers are provided within removable pumping cartridges that are constructed and configured to be coupled to a reusable pump drive component. In other embodiments, the pumping cartridges include multiple pump chambers, which pump chambers are operated so that a pump flow rate of one pump chamber is a predetermined fraction of the pump flow rate of another pump chamber within the pumping cartridge.
摘要翻译：公开了一种用于以期望的平均流量泵送流体的系统，其通过向泵室施加预定的力并且泵浦泵室的出口阀以从其输送流体。在一些实施例中，泵室设置在可拆卸的泵筒内，其被构造和配置为联接到可重复使用的泵驱动部件。在其他实施例中，泵筒包括多个泵室，泵室被操作，使得一个泵室的泵流量是泵送盒内的另一泵室的泵流量的预定分数。

62. 发明申请

US20030092961A1 Optimized pulsatile-flow ventricular-assist device and total artificial heart 审中-公开
公开(公告)号：US20030092961A1
公开(公告)日：2003-05-15
申请号：US10064141
申请日：2002-06-13
发明人： Theodosios Korakianitis , Lonn Grandia
IPC分类号： A61N001/362
CPC分类号： A61M1/1096 , A61M1/1005 , A61M1/1037 , A61M1/1055 , A61M1/1063 , A61M1/1081 , A61M1/1086 , A61M1/1087 , A61M1/1098 , A61M1/122 , A61M2205/33 , A61M2205/3303
摘要： A method of optimizing a mechanical cardiac pumping device includes modeling the circulatory system of the patient who will receive the mechanical cardiac pumping device and identifying an operating condition of the native heart to which the device will respond. The model is used to determine the required blood volume to be ejected from the device and an initial estimate of the power required to be provided to the mechanical cardiac pumping device is provided in order to provide the required ejected blood volume. The resultant ejected blood volume is evaluated with data obtained from the model and the estimate of the power requirement is then updated. The above steps are iteratively performed until the power required to obtain the necessary ejected blood volume is identified. Possible variations of power and pumping rate that allow the mechanical cardiac pumping device to provide the required volume are determined and the variation that best matches the physiological constraints of the patient and minimizes the power required by the mechanical cardiac pumping device is selected. The steps are iteratively performed until the mechanical cardiac pumping device is optimized to respond to each desired operating condition of the native heart.

63. 发明申请

US20030060675A1 Cardiopulmonary life support system 失效
标题翻译：心肺生命支持系统
公开(公告)号：US20030060675A1
公开(公告)日：2003-03-27
申请号：US10005537
申请日：2001-12-07
发明人： Byoung G. Min , Yong S. Won , Kyung Sun , Kwang J. Baek , Hyuk S. Lee , Yang R. Roh , Chang M. Hwang , Jung C. Lee , Whang J. Lee
IPC分类号： A61N001/362
CPC分类号： A61M1/1096 , A61M1/1006 , A61M1/1037 , A61M1/1039 , A61M1/1049 , A61M1/1087 , A61M1/12 , A61M1/1698
摘要： A cardiopulmonary life support system is disclosed. The life support system comprises a housing defined by a top side, a bottom side, and an inner periphery. First and second tubes are adjacent to each other in the housing, and the first and second tubes each have an input port and an output port. An alternating member is attached to the housing and disposed between the first and second tubes. The alternating member alternately squeezes the first and second tubes.
摘要翻译：公开了一种心肺生命支持系统。寿命支持系统包括由顶侧，底侧和内周限定的壳体。第一和第二管在壳体中彼此相邻，并且第一和第二管各自具有输入端口和输出端口。交替构件附接到壳体并且设置在第一和第二管之间。交替构件交替挤压第一和第二管。

64. 发明授权

US5941813A Cardiac assist device 失效
标题翻译：心脏辅助装置
公开(公告)号：US5941813A
公开(公告)日：1999-08-24
申请号：US898302
申请日：1997-07-22
申请人： Hans-Hinrich Sievers , Wolfgang Kloess , Wolfgang Daum
发明人： Hans-Hinrich Sievers , Wolfgang Kloess , Wolfgang Daum
IPC分类号： A61F2/24 , A61M1/10 , A61M1/12 , F04D13/06 , F04D15/00 , F04D29/24 , H02K5/128
CPC分类号： H02K5/1282 , A61M1/101 , A61M1/1036 , A61M1/1087 , A61M1/122 , F04D13/0673 , F04D15/0022 , F04D29/247 , F05C2251/08 , H02K5/1285
摘要： In a cardiac assist device, a housing has an inlet and outlet connectable to a patient's cardiovascular system. A pump is located within the housing to force blood that has entered through the inlet out through the outlet. The pump is connectable between the patient's left atrium and the aorta so as to assist the function of the left ventricle. A motor unit is also disposed within the housing, hermetically sealed from the pump. The whole unit is wholly implantable in a patient's chest. Permanently sealable valves, disposed in the inlet and outlet, may be closed without any invasive procedure to isolate the device from the heart once cardiac function assist is no longer required. The device may remain implanted within the patient indefinitely after the valves have been closed, and there is no requirement for a surgical procedure to remove the device once it is de-activated.
摘要翻译：在心脏辅助装置中，壳体具有可连接到患者心血管系统的入口和出口。泵位于壳体内，以迫使通过出口穿过入口的血液通过出口。泵可连接在患者的左心房和主动脉之间，以协助左心室的功能。电机单元也设置在壳体内，与泵气密密封。整个单元完全植入病人的胸部。设置在入口和出口的永久可密封的阀可以在不需要心脏功能辅助的情况下关闭而无需任何侵入性的过程来将装置与心脏隔离。在阀已经关闭之后，该装置可以无限期地植入患者体内，并且一旦外科手术被去激活就不需要移除该装置。

65. 发明授权

US3783453A Self-regulating artificial heart 失效
标题翻译：自我调节的人造心脏
公开(公告)号：US3783453A
公开(公告)日：1974-01-08
申请号：US3783453D
申请日：1971-12-23
申请人： BOLIE V
发明人： BOLIE V
IPC分类号： A61M1/10 , A61M1/12 , A61F1/24
CPC分类号： A61M1/1065 , A61M1/1037 , A61M1/106 , A61M1/1086 , A61M1/1087 , A61M1/1096 , A61M1/12 , A61M2205/3334
摘要： This invention describes a complete artificial heart system which is capable of providing complete self-regulative control of the pumping action of the heart. It comprises a right and left ventricular bladder connected to the blood system. These bladders are housed in right and left ventricular chambers, the space between the bladder and the chamber being filled with a drive fluid. Means are provided for sensing the volume of blood in the right and the left ventricular bladders. There is a power fluid system which comprises a sump maintained at atmospheric pressure, a pump, a flow control means and a switching means. The right and left sensors in the corresponding right and left ventricular chambers have outputs which are functions of the blood volume in the right and left ventricular bladders. A control means takes these sensor outputs and computes two control signals, one of which is a function of the difference between the volumes in the right and the left ventricular bladders, and the other is a function of the sum of the volumes in the right and the left ventricular bladders. The sum function goes to control the rate of flow of the power fluid and the difference function goes to control the switching. The switching means is provided so that when one bladder, for example the right ventricular bladder, becomes fully extended the left ventricular bladder becomes fully compressed, whereupon the drive fluid is switched into the right ventricular chamber to compress the bladder and push its contained blood out into the body system; at the same time, the power fluid that was filling the left chamber is released to flow back to the sump.
摘要翻译：本发明描述了一种完整的人造心脏系统，其能够提供对心脏的泵送动作的完全自我调节控制。它包括连接到血液系统的右心室和左心室膀胱。这些囊被容纳在右心室和左心室中，膀胱和腔室之间的空间充满驱动流体。提供用于感测右心室和左心室囊中的血液体积的装置。

66. 发明授权

US3739573A Device for converting electrical energy to mechanical energy 失效
标题翻译：将电能转换为机械能量的装置
公开(公告)号：US3739573A
公开(公告)日：1973-06-19
申请号：US3739573D
申请日：1970-10-20
申请人： TYCO LABORATORIES INC
发明人： GINER J
IPC分类号： A61M1/10 , A61M1/12 , C25B1/00 , F04B17/00 , F04B43/107 , H02N11/00 , F01K25/08
CPC分类号： H02N11/006 , A61M1/1037 , A61M1/1049 , A61M1/106 , A61M1/1087 , A61M1/1096 , A61M1/127 , C25B1/00 , F04B17/00 , F04B43/107
摘要： An electrochemical energy conversion device comprising a container, one or more electrochemical cells in said container adapted to produce a gas or to consume said gas according to the polarity of current passed by said one or more cells, polarity reversible means for passing current through said one or more cells, and pressure-responsive moveable mechanical means arranged for movement according to changes in the gas pressure in said container. Each cell comprises a gas producing and consuming electrode, a counter electrode, and an electrolyte contacted by both electrodes.
摘要翻译：一种电化学能量转换装置，包括容器，所述容器中的一个或多个电化学电池适于产生气体或根据由所述一个或多个电池通过的电流的极性消耗所述气体，极性可逆装置，用于使电流通过所述一个或多个电池或更多的电池，以及压力响应的可移动的机械装置，其布置成根据所述容器中的气体压力的变化而运动。每个电池包括气体产生和消耗电极，对电极和由两个电极接触的电解质。

67. 发明授权

US3453967A Pump 失效
公开(公告)号：US3453967A
公开(公告)日：1969-07-08
申请号：US3453967D
申请日：1967-09-15
申请人： ELECTRO MEDICAL SYSTEMS INC
发明人： SPURLOCK JACK M , DURFEE ROBERT L
IPC分类号： A61M1/10 , F04B43/08 , F04B43/00
CPC分类号： F04B43/084 , A61M1/1037 , A61M1/1046 , A61M1/1087 , A61M1/1096 , A61M1/1098

68. 发明授权

US3305097A High pressure peristaltic pump for separation apparatus 失效
标题翻译：用于分离设备的高压蠕动泵
公开(公告)号：US3305097A
公开(公告)日：1967-02-21
申请号：US28349163
申请日：1963-05-27
申请人： SCIENTIFIC INDUSTRIES
发明人： SAMUEL NATELSON
IPC分类号： A61M1/10 , F04B43/08 , F04B43/113
CPC分类号： F04B43/1133 , A61M1/1006 , A61M1/1041 , A61M1/106 , A61M1/1087 , A61M1/1089 , A61M1/1096 , F04B43/082

69. 发明授权

US2474665A Pneumatic blood treating apparatus 失效
标题翻译：气动血液处理仪
公开(公告)号：US2474665A
公开(公告)日：1949-06-28
申请号：US65022446
申请日：1946-02-26
申请人： FRANK J GUARINO , VINCENT T GUARINO , LOUIS J GUARINO
发明人： GUARINO JOHN R
IPC分类号： A61M1/10 , A61M1/32
CPC分类号： A61M1/10 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/1087 , A61M1/1096 , A61M1/32 , Y10S128/03

70. 发明专利

JP2018038843A 血液処置システムおよび方法审中-公开
公开(公告)号：JP2018038843A
公开(公告)日：2018-03-15
申请号：JP2017212181
申请日：2017-11-01
申请人：デカ・プロダクツ・リミテッド・パートナーシップ
发明人：ウィルト、マイケルジェイ. , ファンデルメルヴェ、ディルクエイ. , バランタイン、トッドエイ. , グラント、ケビンエル. , ロッセ、ジョナサンピー. , フリン、キャサリンエヌ. , イー、ブライアンケイ.
IPC分类号： F04B43/06 , A61M1/16
CPC分类号： A61M1/1601 , A61K33/00 , A61M1/1006 , A61M1/1037 , A61M1/1062 , A61M1/1087 , A61M1/1096 , A61M1/14 , A61M1/16 , A61M1/1605 , A61M1/1613 , A61M1/1619 , A61M1/1654 , A61M1/1656 , A61M1/1658 , A61M1/166 , A61M1/1664 , A61M1/1666 , A61M1/1668 , A61M1/1692 , A61M1/267 , A61M1/301 , A61M1/34 , A61M1/341 , A61M1/3413 , A61M1/3609 , A61M1/3621 , A61M1/3627 , A61M1/3638 , A61M1/3672 , A61M5/172 , A61M2205/12 , A61M2205/15 , A61M2205/18 , A61M2205/3306 , A61M2205/3313 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/3379 , A61M2205/3569 , A61M2205/3584 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2230/65 , G06F19/00 , G06F19/3481 , Y02A50/395 , Y02A90/26
摘要：【課題】透析機能を行うべく協働する複数のアクチュエータと、透析機能を監視すべく協働する複数のセンサとを備える透析システムを提供する。【解決手段】血液透析システムは、ユーザインターフェースモデルレイヤ6602と、ユーザインターフェースモデルレイヤの下位の治療レイヤ6601と、治療レイヤの下位のマシンレイヤ6603とを備える。ユーザインターフェースモデルレイヤは、グラフィカルユーザインターフェースの状態を管理し、入力を受信する。治療レイヤは、グラフィカルユーザインターフェースからの入力に基づき、治療コマンドを生成するステートマシンを実行する。マシンレイヤは、治療コマンドに基づきアクチュエータにコマンドを提供する。【選択図】図66

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