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61. 发明申请

WO9953047A2 PORCINE ADENOVIRUS TYPE 3 GENOME 审中-公开
公开(公告)号：WO9953047A2
公开(公告)日：1999-10-21
申请号：PCT/US9908220
申请日：1999-04-15
申请人： UNIV SASKATCHEWAN , REDDY POLICE SESHIDHAR , TIKOO SURESH KUMAR , BABIUK LORNE A
发明人： REDDY POLICE SESHIDHAR , TIKOO SURESH KUMAR , BABIUK LORNE A
IPC分类号： G01N33/50 , A61K39/235 , A61K48/00 , A61P31/12 , A61P37/04 , C07K14/075 , C07K16/08 , C12N5/10 , C12N7/04 , C12N15/09 , C12N15/861 , C12Q1/68 , G01N33/53 , G01N33/566 , C12N15/00
CPC分类号： C12N15/86 , A61K48/00 , A61K2039/53 , C07K14/005 , C12N7/00 , C12N2710/10322 , C12N2710/10343 , C12N2710/10362
摘要： The complete nucleotide sequence of the genome of porcine adenovirus type 3 (PAV-3) is provided. Methods for construction of infectious PAV genomes by homologous recombination in procaryotic cells are provided. Recombinant PAV viruses are obtained by transfection of mammalian cells with recombinant PAV genomes. The PAV-3 genome can be used as a vector for the expression of heterologous nucleotide sequences, for example, for the preparation and administration of subunit vaccines to swine or other mammals. In addition, PAV-3 vectors can be used for gene therapy and expression of heterologous polypeptides. PAV-3 genome sequences can also be used for diagnostic purposes, to detect the presence of PAV-3 DNA in a subject or biological sample.
摘要翻译：提供猪腺病毒3型（PAV-3）基因组的完整核苷酸序列。提供了在原核细胞中通过同源重组构建感染性PAV基因组的方法。通过用重组PAV基因组转染哺乳动物细胞获得重组PAV病毒。 PAV-3基因组可用作异源核苷酸序列表达的载体，例如用于制备和施用猪或其他哺乳动物的亚单位疫苗。此外，PAV-3载体可用于基因治疗和异源多肽的表达。 PAV-3基因组序列也可用于诊断目的，以检测受试者或生物样品中PAV-3 DNA的存在。

62. 发明申请

WO9903817B1 ALIPHATIC PROPARGYLAMINES AS CELLULAR RESCUE AGENTS 审中-公开
标题翻译：作为细胞拯救剂的脂肪族丙烷胺
公开(公告)号：WO9903817B1
公开(公告)日：1999-07-01
申请号：PCT/CA9800683
申请日：1998-07-14
申请人： UNIV SASKATCHEWAN , PATERSON I ALICK , DURDEN DAVID A , DAVIS BRUCE A , DYCK LILLIAN E , YU PETER H , LI XIN MIN , BOULTON ALAN A
发明人： PATERSON I ALICK , DURDEN DAVID A , DAVIS BRUCE A , DYCK LILLIAN E , YU PETER H , LI XIN-MIN , BOULTON ALAN A
IPC分类号： A61P9/00 , A61K31/13 , A61P25/00 , A61P25/14 , A61P25/16 , A61P25/28 , A61P27/02 , A61P43/00 , C07C211/23
CPC分类号： C07C211/23
摘要： The present invention relates to the use of a group of propargylamines of general formula (I) wherein R is hydrogen or CH3 and R is (CH2)nCH3 and n is an integer from 0 to 16, and salts thereof, as cellular rescue agents in the treatment and prevention of diseases in which cell death occurs by apoptosis. Some of the compounds of formula (I) are novel. The invention is also directed to the use of these compounds in the treatment of these diseases, as well as to processes for the preparation of the compounds.
摘要翻译：本发明涉及一组通式（I）的炔丙胺的用途，其中R 1是氢或CH 3且R 2是（CH 2）n CH 3且n是0-16的整数，及其盐作为细胞拯救剂用于治疗和预防细胞死亡通过凋亡发生的疾病。式（I）的一些化合物是新颖的。本发明还涉及这些化合物在治疗这些疾病中的用途，以及制备这些化合物的方法。

63. 发明申请

WO9516048A3 RECOMBINANT PROTEIN PRODUCTION IN BOVINE ADENOVIRUS EXPRESSION VECTOR SYSTEM 审中-公开
标题翻译：牛血清型表达载体系统中重组蛋白的生产
公开(公告)号：WO9516048A3
公开(公告)日：1995-09-28
申请号：PCT/CA9400678
申请日：1994-12-09
申请人： UNIV SASKATCHEWAN
发明人： MITTAL SURESH K , GRAHAM FRANK L , PREVEC LUDVIK , BABIUK LORNE A
IPC分类号： A61K48/00 , C07K14/075 , C12N7/01 , C12N15/861 , C12N15/86 , C12N5/10 , C12R1/92
CPC分类号： C12N15/86 , A61K48/00 , C07K14/005 , C12N2710/10322 , C12N2710/10343 , C12N2710/10352
摘要： The present invention relates to novel live bovine adenovirus (BAV) expression vector systems in which part or all of one or both of the early region 1 (E1) and early region 3 (E3) genes are deleted and replaced by a foreign gene or fragment thereof and novel recombinant mammalian cell lines stably transformed with BAV E1 sequences, and therefore, express E1 gene products capable of allowing replication therein of a bovine adenovirus having an E1 deletion replaced by a heterologous nucleotide sequence encoding a foreign gene or fragment thereof and their use in production of (antigenic) polypeptides or fragments thereof for the purpose of live recombinant virus or subunit vaccine or for other therapies.

64. 发明公开

EP3075028A4 DIELECTRIC RESONATOR ANTENNA ARRAYS 有权
标题翻译：二极管谐振器
公开(公告)号：EP3075028A4
公开(公告)日：2017-07-19
申请号：EP14871362
申请日：2014-12-19
申请人： UNIV SASKATCHEWAN
发明人： TAYFEH ALIGODARZ MOHAMMADREZA , KLYMYSHYN DAVID , RASHIDIAN ATABAK , LIU XUN
IPC分类号： H01Q1/38 , H01P3/08 , H01Q9/04 , H01Q21/06
CPC分类号： H01Q9/0485 , H01P5/12 , H01Q1/50 , H01Q21/0087 , H01Q21/06
摘要： Arrays of low permittivity Polymer-based Resonator Antenna elements with different configurations. Individual array elements can be fabricated with complicated geometries; these elements can be assembled into complicated patterns as a single monolithic fabricated structure using narrow wall connecting structures, which removes the requirement to position and assemble the array elements. Monolithic array structures can be assembled as sub-arrays in larger array structures. Elements, sub-arrays, and arrays can also be formed by inserting dielectric materials into cavities defining their lateral geometries, and fabricated in polymer templates. The polymer templates can be removed or retained to function as part of the antenna. Effective excitation is achieved by one of a number of coupling methods, including standing metal strip feeding on the vertical sides of the elements, feeding by tall metal transmission lines in contact or in close proximity to the vertical sides of the elements, modified microstrip feeding, or aperture feeding by using a slot in the metal plane underneath the elements. The wideband array feeds are realized by optimized transmission line distribution networks which include wideband matching sections.
摘要翻译：低介电常数阵列具有不同配置的基于聚合物的谐振器天线元件。单个阵列元件可以制造成复杂的几何形状; 这些元件可以使用窄壁连接结构作为单个单片制造结构组装成复杂图案，这消除了定位和组装阵列元件的要求。单片阵列结构可以组装成较大阵列结构中的子阵列。元件，子阵列和阵列也可以通过将介电材料插入到限定其横向几何形状的空腔中并且在聚合物模板中制造而形成。聚合物模板可以被移除或保留以作为天线的一部分。通过多种耦合方法之一来实现有效的激励，包括在元件的垂直侧面上竖立金属条馈电，通过与元件的垂直侧面接触或紧密接触的高金属传输线进行馈送，修改的微带馈送，或者通过使用元件下方的金属平面中的狭缝来馈送孔。宽带阵列馈电通过包括宽带匹配部分的优化传输线分布网络来实现。

65. 发明公开

EP2585784A4 LIQUID-TO-AIR MEMBRANE ENERGY EXCHANGER 审中-公开
标题翻译：能量交换液空REED
公开(公告)号：EP2585784A4
公开(公告)日：2016-02-24
申请号：EP11797695
申请日：2011-06-22
申请人： VENMAR CES INC , UNIV SASKATCHEWAN
发明人： ERB BLAKE , BESANT ROBERT W , SIMONSON CAREY J , HEMINGSON HOWARD
IPC分类号： F28D15/00 , F24F3/147 , F24F12/00 , F28D9/00 , F28D21/00 , F28F3/12
CPC分类号： F24F3/147 , F24F3/1417 , F24F12/001 , F24F12/002 , F24F12/006 , F24F2001/0092 , F24F2003/1435 , F28D15/00 , F28D21/0015 , Y02B30/545 , Y02B30/563

66. 发明公开

EP2734614A4 ISOLATED BRACHYSPIRA AND METHODS AND COMPOSITIONS FOR EXPANDING AND ISOLATING BRACHYSPIRA 审中-公开
标题翻译：隔离短螺旋体和膨胀和隔离短螺旋体的方法和组合物
公开(公告)号：EP2734614A4
公开(公告)日：2015-01-21
申请号：EP12814810
申请日：2012-07-18
申请人： UNIV SASKATCHEWAN
发明人： HARDING JOHN CLARE SAMUEL , HILL JANET ELIZABETH , RUBIN JOSEPH , CHIRINO TREJO MANUEL
IPC分类号： A61K39/00 , A61P31/04 , A61P37/04 , C07K14/20 , C07K16/12 , C12N1/20 , C12R1/01
CPC分类号： C07K14/20 , A61K39/00 , C07K16/1207 , C12N1/20 , C12R1/01

67. 发明公开

EP2588428A4 METHODS OF KINOME ANALYSIS 审中-公开
标题翻译：激酶组分析程序
公开(公告)号：EP2588428A4
公开(公告)日：2014-03-05
申请号：EP11800019
申请日：2011-06-30
申请人： UNIV SASKATCHEWAN
发明人： KUSALIK TONY , LI YUE , NAPPER SCOTT , GABRIEL PHILIP , ARSENAULT RYAN
IPC分类号： G01N33/68 , C04B30/02 , G06F19/10 , G06F19/12 , G06F19/20 , G06F19/24
CPC分类号： G06F19/10 , G06F19/12 , G06F19/20 , G06F19/24

68. 发明公开

EP2285964A4 PHAGE LAMBDA DISPLAY CONSTRUCTS 审中-公开
标题翻译： LAMBDA PHAG显示结构
公开(公告)号：EP2285964A4
公开(公告)日：2012-11-07
申请号：EP09741613
申请日：2009-05-11
申请人： UNIV SASKATCHEWAN
发明人： HAYES SIDNEY
IPC分类号： C12N15/10 , A61K35/76 , A61K39/12 , A61K48/00 , C04B40/02 , C12N7/00 , C12N15/34 , C12N15/73 , C40B50/06
CPC分类号： C12N15/1037 , A61K2039/5256 , C07K14/005 , C07K2319/735 , C12N7/00 , C12N2795/10321 , C12N2795/10322 , C40B40/02
摘要： Bacteriophages in general and lambda phage in particular are powerful, flexible reagents who have yet to be exploited to their full potential. As discussed herein, the lambda phage head and/or genome comprises an easy to use and highly efficient delivery vehicle for delivering the expression products of a gene of interest systemically or to a particular tissue.

69. 发明公开

EP2225194A4 PROCESS FOR THE PRODUCTION OF POLYOL BASE CATALYSTS 审中-公开
标题翻译：生产多元醇基催化剂的方法
公开(公告)号：EP2225194A4
公开(公告)日：2012-07-11
申请号：EP08853591
申请日：2008-12-01
申请人： UNIV SASKATCHEWAN
发明人： REANEY MARTIN J T , SHEN JIANHENG , SOVERAN DOUGLAS W
IPC分类号： C07C29/70 , B01J31/02 , C07C31/30 , C07C67/02
CPC分类号： C11C3/003 , B01J31/0212 , B01J2231/49 , B01J2531/11 , B01J2531/12 , B01J2531/13 , B01J2531/14 , C07C29/70 , C07C29/94 , C07C31/30 , C07C67/03 , C07C69/24 , C07C69/52

70. 发明公开

EP1977222A4 SYSTEMS AND METHODS FOR DETECTING AN IMAGE OF AN OBJECT BY USE OF AN X-RAY BEAM HAVING A POLYCHROMATIC DISTRIBUTION 审中-公开
标题翻译：系统和方法用于图像捕获的目的是通过X射线意味着彩瓷分布
公开(公告)号：EP1977222A4
公开(公告)日：2011-12-07
申请号：EP07762560
申请日：2007-01-24
申请人： UNIV NORTH CAROLINA , BROOKHAVEN SCIENCE ASS LLC , UNIV SASKATCHEWAN
发明人： PARHAM CHRISTOPHER A , PISANO ETTA D , ZHONG ZHONG , CONNOR DEAN , CHAPMAN LEROY DEAN
IPC分类号： G01N23/04
CPC分类号： G01N23/046 , A61B6/508 , A61B6/583 , G01N2223/419

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