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61. 发明专利

AU2012305327B2 Polymer-type fluorescent molecule probe 未知
公开(公告)号：AU2012305327B2
公开(公告)日：2016-07-14
申请号：AU2012305327
申请日：2012-09-05
申请人： MAEDA HIROSHI
发明人： MAEDA HIROSHI , HASHIZUME MAKOTO , FANG JUN , NAKAMURA HIDEAKI , QIN HAIBO , HACKBARTH STEFFEN , MURATA MASAHARU
IPC分类号： A61K49/00 , A61B1/00 , A61K41/00 , G01N21/64
摘要： The present invention provides a fluorescent molecule probe for efficient fluorescent detection (visualization) of tumors or for implementing fluorescent detection and photodynamic therapy; more specifically, the present invention provides a polymer-type fluorescent molecule probe for fluorescent detection of tumors, the probe including a composite comprising a fluorescent molecule and a biocompatible polymer.

62. 发明专利

AU2012305327A1 Polymer-type fluorescent molecule probe 未知
公开(公告)号：AU2012305327A1
公开(公告)日：2014-04-24
申请号：AU2012305327
申请日：2012-09-05
申请人： MAEDA HIROSHI
发明人： MAEDA HIROSHI , HASHIZUME MAKOTO , FANG JUN , NAKAMURA HIDEAKI , QIN HAIBO , HACKBARTH STEFFEN , MURATA SEIJI
IPC分类号： A61K49/00 , A61B1/00 , A61K41/00 , G01N21/64
摘要： The present invention provides a fluorescent molecule probe for efficient fluorescent detection (visualization) of tumors or for implementing fluorescent detection and photodynamic therapy; more specifically, the present invention provides a polymer-type fluorescent molecule probe for fluorescent detection of tumors, the probe including a composite comprising a fluorescent molecule and a biocompatible polymer.

63. 发明专利

AT525437T 未知
公开(公告)号：AT525437T
公开(公告)日：2011-10-15
申请号：AT06731788
申请日：2006-04-13
申请人： MAEDA HIROSHI
发明人： GREISH KHALED , MAEDA HIROSHI
IPC分类号： C08L35/06 , A61K31/409 , A61K31/704 , A61K31/7048 , A61K33/24 , A61K47/48 , A61P35/00 , C08K5/00

64. 发明专利

DE69630561T2 未知
公开(公告)号：DE69630561T2
公开(公告)日：2004-06-09
申请号：DE69630561
申请日：1996-08-22
申请人： MAEDA HIROSHI
发明人： MAEDA HIROSHI , AKAIKE TAKAAKI , MIYAMOTO YOICHI , YOSHIDA MASAKI
IPC分类号： A61K31/519 , A61P9/12
摘要： Antihypertensive agent containing as its active ingredient 4-amino-6-hydroxypyrazoloÄ3,4-dÜpyrimidine (AHPP) or its derivatives represented by the general formula (I) where R is hydrogen atom, alkyl group, alkoxy group or aryl group. The antihypertensive agents of the present invention show a mild and reliable blood pressure lowering activity and have a different mode of action over the currently available antihypertensive agents.

65. 发明专利

DE69630561D1 未知
公开(公告)号：DE69630561D1
公开(公告)日：2003-12-11
申请号：DE69630561
申请日：1996-08-22
申请人： MAEDA HIROSHI
发明人： MAEDA HIROSHI , AKAIKE TAKAAKI , MIYAMOTO YOICHI , YOSHIDA MASAKI
IPC分类号： A61K31/519 , A61P9/12
摘要： Antihypertensive agent containing as its active ingredient 4-amino-6-hydroxypyrazoloÄ3,4-dÜpyrimidine (AHPP) or its derivatives represented by the general formula (I) where R is hydrogen atom, alkyl group, alkoxy group or aryl group. The antihypertensive agents of the present invention show a mild and reliable blood pressure lowering activity and have a different mode of action over the currently available antihypertensive agents.

66. 发明专利

DE69815769D1 未知
公开(公告)号：DE69815769D1
公开(公告)日：2003-07-31
申请号：DE69815769
申请日：1998-08-20
申请人： MAEDA HIROSHI
发明人： MAEDA HIROSHI , SAWA TOMOHIRO , AKAIKE TAKAAKI
IPC分类号： A61K38/44 , A61K45/06 , A61K47/48 , A61P35/00 , C12N11/08 , A61K7/02
摘要： The present invention provides an antitumor agent which is a combination of an oxidoreductase being chemically conjugated with a polymer, and of a substrate of the oxidoreductase. The antitumor agent exhibits an improved tumor selective cytotoxic activity.

67. 发明专利

AU7964300A High-temperature oxide superconductor wire and method for preparing the same 未知
公开(公告)号：AU7964300A
公开(公告)日：2001-06-06
申请号：AU7964300
申请日：2000-10-30
申请人： MAEDA HIROSHI , SUMITOMO ELECTRIC INDUSTRIES
发明人： MAEDA HIROSHI , AYAI NAOKI , UEYAMA MUNETSUGU , HAYASHI KAZUHIKO , SATO MITSUNORI
IPC分类号： H01L39/14 , H01L39/24 , H01B12/04 , H01B12/10 , H01B13/00
摘要： There is provided an oxide high-temperature superconducting wire having a structure with a high-resistance element arranged to reduce ac loss and also prevented from having an effect impairing superconducting properties including critical current density, and a method of producing the same. The oxide high-temperature superconducting wire includes: an oxide superconductor filament (1) formed of a Bi(Pb)-Sr-Ca-Cu-O-based superconductor; a sheath (2) formed of silver and covering the oxide superconductor filament (1); a high-resistance element (3) formed of a strontium-vanadium oxide and coating the sheath (2); and a coating (4) formed of silver and coating a large number of sheathes (2) coated with the high-resistance element (3).

68. 发明专利

DE69330091D1 未知
公开(公告)号：DE69330091D1
公开(公告)日：2001-05-10
申请号：DE69330091
申请日：1993-01-14
申请人： MAEDA HIROSHI
发明人： MAEDA HIROSHI , MIYAMOTO YOICHI , AKAIKE TAKAAKI
IPC分类号： A61K31/415 , C07D233/06

69. 发明专利

AT200280T 未知
公开(公告)号：AT200280T
公开(公告)日：2001-04-15
申请号：AT93901552
申请日：1993-01-14
申请人： MAEDA HIROSHI
发明人： MAEDA HIROSHI , MIYAMOTO YOICHI , AKAIKE TAKAAKI
IPC分类号： A61K31/415 , C07D233/06

70. 发明专利

DE3853493T2 未知
公开(公告)号：DE3853493T2
公开(公告)日：1995-07-27
申请号：DE3853493
申请日：1988-05-26
申请人： MAEDA HIROSHI , KURARAY CO
发明人： MAEDA HIROSHI , SUZUKI FUJIO , ODA TATSUYA
IPC分类号： A61K38/44 , C12N9/02
摘要： The invention provides a superoxide dismutase derivative of the general formula [SOD] [Z]n wherein [SOD] represents a superoxide dismutase having 1 to 22 or 24 groups each derived from an amino group by removal of one hydrogen atom in lieu of amino groups; [Z] represents a monovalent copolymer group, constituting units of which are a group of the formula wherein R , R , R and R each represents a hydrogen atom or a residue derived by removal of a hydroxyl group from an alkanol of 1 to 8 carbon atoms, an ethylene glycol monoalkyl ether containing an alkyl moiety of 1 to 4 carbon atoms or a glycerin dialkyl ether containing alkyl moieties of 1 to 4 carbon atoms, provided that either R or R and either R or R each represents a hydrogen atom, and a residue derived from the group of the above-mentioned formula by removal of OR , OR , OR or OR group from one of its COOR , COOR , COOR and COOR groups (where the bond on the carbon atom of the carbonyl group is attached to [SOD]), said monovalent copolymer group having an average molecular weight of 500 to 200,000; and n represents an integer of 1 to 22 or 24 corresponding to the number of said groups each derived from an amino group by removal of one hydrogen atom in said [SOD], or a pharmaceutically acceptable salt thereof. There also is provided a method for producing the above derivative and salt. The invention is further directed to medicinal uses and pharmaceutical compositions for oral administration.

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