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    • 63. 发明授权
    • Piperidinylamino tricyclic compounds as substance P antagonists
    • 哌啶基氨基三环化合物作为物质P拮抗剂
    • US6143767A
    • 2000-11-07
    • US351011
    • 1999-07-12
    • Hiroki KoikeHiroaki Wakabayashi
    • Hiroki KoikeHiroaki Wakabayashi
    • C07D471/04C07D487/04C07D401/04A61K31/454A61K31/4545
    • C07D471/04C07D487/04
    • This invention provides a compound of the formula: ##STR1## and its pharmaceutically acceptable salts, wherein Ar.sup.1 is selected from the group having the formulae: ##STR2## wherein, R.sup.1 and R.sup.2 are independently hydrogen or C.sub.1 -C.sub.6 alkyl;W is (CH.sub.2).sub.a wherein n is from 1 to 3, or --CH.dbd.CH--;X is C.sub.1 -C.sub.6 alkoxy or halo C.sub.1 -C.sub.6 alkoxy; andAr.sup.2 is phenyl optionally substituted by halogen atom.These compounds are useful in the treatment of a gastrointestinal disorder, a central nervous system (CNS) disorder, an inflammatory disease, emesis, urinary incontinence, pain, migraine, sunburn, angiogenesis, diseases, disorders and adverse conditions caused by Helicobacter pylori, or the like in a mammalian subject, especially humans.
    • 本发明提供下式的化合物及其药学上可接受的盐,其中Ar 1选自具有下式的基团:其中,R 1和R 2独立地为氢或C 1 -C 6烷基; W为(CH 2)a,其中n为1至3,或-CH = CH-; X是C 1 -C 6烷氧基或卤代C 1 -C 6烷氧基; 并且Ar 2是任选被卤素原子取代的苯基。 这些化合物可用于治疗胃肠道疾病,中枢神经系统(CNS)病症,炎性疾病,呕吐,尿失禁,疼痛,偏头痛,晒伤,血管发生,疾病,病症和由幽门螺杆菌引起的不利条件,或 哺乳动物受试者,特别是人类。
    • 65. 发明授权
    • Non-volatile ferroelectric memory device with leakage preventing function
    • 具有防漏功能的非易失性铁电存储器件
    • US5615144A
    • 1997-03-25
    • US511527
    • 1995-08-04
    • Tohru KimuraHiroki Koike
    • Tohru KimuraHiroki Koike
    • G11C14/00G11C11/22G11C11/408G11C17/00H01L21/8246H01L27/10H01L27/105
    • G11C11/22
    • A non-volatile ferroelectric memory device includes a plurality of memory cells provided in a matrix manner, each of which comprises a transistor having a gate and source and drain regions formed in a semiconductor region, and a ferroelectric capacitor having first and second electrodes and a ferroelectric layer interposed between the first and second electrodes. The second electrode is connected to one of the source and drain regions of the transistor. The memory device further includes a plurality of pairs of bit lines, each of the bit lines of each of the pairs being connected to the other of the source and drain regions of the transistor of each memory cell in a column of the plurality of memory cells, a plurality of word lines each of which is connected to the gate of the transistor of each memory cell in a row of the plurality of memory cells, a plate potential section for generating a first predetermined potential intermediate between a reference potential and a high DC voltage and supplying the first potential to the first electrode of each of the plurality of memory cells, a well potential section for generating a second predetermined potential lower than the first potential with respect to the reference potential and supplying the second potential to the semiconductor region of each of the plurality of transistors, and a sense amplifier section for sensing a data using potentials on the bit lines of each of the plurality of pairs of bit lines. The well potential section functions as a preventing section for preventing a leakage current from flowing from the ferroelectric layer.
    • 非挥发性铁电存储器件包括以矩阵方式设置的多个存储单元,每个存储单元包括具有形成在半导体区域中的栅极和源极和漏极区域的晶体管,以及具有第一和第二电极的铁电电容器和 介于第一和第二电极之间的铁电层。 第二电极连接到晶体管的源极和漏极区之一。 存储器件还包括多对位线,每对存储器单元的列中的每一对的每个位线连接到每个存储器单元的晶体管的源极和漏极区域中的另一个, 多条字线,每条字线连接到多个存储单元的行中的每个存储单元的晶体管的栅极;平板电位部分,用于产生参考电位和高DC之间的第一预定电位中间值 电压并将第一电位提供给多个存储单元中的每一个的第一电极;井势部分,用于产生相对于参考电位低于第一电位的第二预定电位,并将第二电位提供给半导体区域 所述多个晶体管中的每一个以及用于使用所述多个晶体管中的每一个的位线上的电位来感测数据的读出放大器部分 一对位线。 阱电位部用作防止漏电流从铁电层流出的防止部。
    • 66. 发明授权
    • Ferroelectric random-access memory
    • 铁电随机存取存储器
    • US5600587A
    • 1997-02-04
    • US593686
    • 1996-01-29
    • Hiroki Koike
    • Hiroki Koike
    • G11C14/00G11C11/22G11C11/401G11C11/404
    • G11C11/22
    • The invention provides a nonvolatile random-access memory using memory cells consisting of a ferroelectric capacitor and a switching transistor. The memory has two memory blocks each of which has memory cells arranged in rows and columns, word lines, bit lines, a plate line, sense amplifiers and reference voltage generators. The memory includes a plate line voltage control circuit which impresses supply voltage to the plate line of one memory block and ground potential to the plate line of the other memory block during a transition period preceding to read or write operation and then connects the two plate lines to thereby keep the connected plate lines at an intermediate voltage between supply voltage and ground potential. To retard fatigue of the ferroelectric material by repeated polarization in positive and negative directions, the memory can optionally be operated in a volatile mode.
    • 本发明提供一种使用由铁电电容器和开关晶体管组成的存储单元的非易失性随机存取存储器。 存储器具有两个存储块,每个存储块具有以行和列,字线,位线,板线,读出放大器和参考电压发生器排列的存储单元。 该存储器包括一板式电压控制电路,其在读或写操作之前的转换期间,将一个存储块的板线的电源电压和另一个存储块的板线的接地电位加压,然后将两个板线 从而将连接的板线保持在电源电压和地电位之间的中间电压。 为了通过在正和负方向上重复极化来阻止铁电材料的疲劳,存储器可以可选地以易失性模式操作。