专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

61. 发明授权

US08603004B2 Methods and systems for filtering respiration noise from localization data 有权
标题翻译：用于从定位数据过滤呼吸噪声的方法和系统
公开(公告)号：US08603004B2
公开(公告)日：2013-12-10
申请号：US12835518
申请日：2010-07-13
申请人： Steve Koh , Stuart Rosenberg , Kyungmoo Ryu
发明人： Steve Koh , Stuart Rosenberg , Kyungmoo Ryu
IPC分类号： A61B5/08 , A61B5/05
CPC分类号： A61B5/063 , A61B5/113 , A61B5/721 , A61B90/36 , A61B2017/00053 , A61B2034/2048 , A61B2034/2051 , A61B2034/2053 , A61B2562/0219
摘要： A method of filtering respiration noise from a localization signal includes acquiring a localization signal from at least one position measurement sensor within a localization field and acquiring an acceleration signal for at least one localization field generator (e.g., a patch electrode). A displacement signal for the field generator is calculated, for example by integrating the acceleration signal twice, and transformed into the frequency domain in order to calculate a fractional power indicative of patient respiration. The fractional power can then be compared to a threshold value, and the localization signal can be filtered if the fractional power exceeds the threshold value. Alternatively, the acquired acceleration signal can be used to gate collection of data points from the localization signal.
摘要翻译：从定位信号过滤呼吸噪声的方法包括从定位场内的至少一个位置测量传感器获取定位信号，并获取至少一个定位场发生器（例如，贴片电极）的加速度信号。计算场发生器的位移信号，例如通过对加速度信号进行两次积分，并将其变换到频域以便计算指示患者呼吸的分数功率。然后可以将分数功率与阈值进行比较，如果分数功率超过阈值，则可以对定位信号进行滤波。或者，获取的加速度信号可以用于从定位信号门控收集数据点。

62. 发明授权

US08583230B2 Systems and methods for selectively limiting multi-site ventricular pacing delays during optimization of cardiac resynchronization therapy parameters 有权
标题翻译：用于在优化心脏再同步治疗参数期间选择性限制多部位心室起搏延迟的系统和方法
公开(公告)号：US08583230B2
公开(公告)日：2013-11-12
申请号：US13009404
申请日：2011-01-19
申请人： Kyungmoo Ryu , Allen Keel , Heidi Hellman , Tomas Svensson
发明人： Kyungmoo Ryu , Allen Keel , Heidi Hellman , Tomas Svensson
IPC分类号： A61N1/00
CPC分类号： A61N1/3627 , A61N1/3684 , A61N1/3712
摘要： Techniques are provided for use with implantable cardiac stimulation devices equipped for multi-site left ventricular (MSLV) cardiac pacing. Briefly, intraventricular and interventricular conduction delays are detected for paced cardiac events. Maximum pacing time delays are determined for use with MSLV pacing where the maximum pacing time delays are set based on the conduction delays to values sufficient to avoid capture problems due to wavefront propagation, such as fusion or lack of capture. MSLV pacing delays are then set to values no greater than the maximum pacing delays and cardiac resynchronization therapy (CRT) is delivered using the MSLV pacing delays. In an example where an optimal interventricular pacing delay (VV) is determined in advance using intracardiac electrogram-based or hemodynamic-based optimization techniques, the optimal value for VV can be used as a limiting factor when determining the maximum MSLV pacing time delays.
摘要翻译：提供技术用于配备用于多部位左心室（MSLV）心脏起搏的可植入心脏刺激装置。简而言之，对于心跳事件，检测到心室内和室间传导延迟。确定最大起搏时间延迟用于MSLV起搏，其中最大起搏时间延迟基于导通延迟设置为足以避免由于波前传播引起的捕获问题，例如融合或缺乏捕获。然后将MSLV起搏延迟设置为不大于最大起搏延迟的值，并使用MSLV起搏延迟传递心脏再同步治疗（CRT）。在使用基于心脏电图或基于血液动力学的优化技术预先确定最佳心室起搏延迟（VV）的示例中，当确定最大MSLV起搏时间延迟时，可以将VV的最佳值用作限制因素。

63. 发明授权

US08538524B2 Systems and methods for detecting far-field oversensing based on signals sensed by the proximal electrode of a multipolar LV lead 有权
标题翻译：基于由多极LV引线的近端电极感测的信号来检测远场过冲的系统和方法
公开(公告)号：US08538524B2
公开(公告)日：2013-09-17
申请号：US13230482
申请日：2011-09-12
申请人： Stuart Rosenberg , Tomas Svensson , Kjell Norén , Edward Karst , Kyungmoo Ryu
发明人： Stuart Rosenberg , Tomas Svensson , Kjell Norén , Edward Karst , Kyungmoo Ryu
IPC分类号： A61N1/368
CPC分类号： A61N1/3704 , A61B5/0464 , A61B5/0468 , A61B5/686 , A61N1/3627 , A61N1/3684
摘要： A device senses cardioelectrical signals using a right atrial (RA) lead, which might include far-field R-waves as well as near-field P-waves. The device concurrently senses events using a proximal electrode of an LV lead, which can sense both P-waves and R-waves as substantially near-field events. Suitable templates are then applied to the signals sensed via the proximal LV electrode to identify the origin of the signals (e.g. atrial vs. ventricular) so as to properly classify the corresponding events sensed in the RA as near-field or far-field events. In this manner, far-field oversensing is conveniently detected.
摘要翻译：一种装置使用右心房（RA）导联感测心电信号，其可能包括远场R波以及近场P波。该装置使用LV引线的近侧电极同时感测事件，其可以感测P波和R波作为基本近场事件。然后将合适的模板施加到经由近端LV电极感测的信号以识别信号的来源（例如心房与心室），以便将在RA中感测到的相应事件适当地分类为近场或远场事件。以这种方式，可以方便地检测远场超检测。

64. 发明授权

US08527049B2 Cardiac resynchronization therapy optimization using vector measurements obtained from realtime electrode position tracking 有权
标题翻译：使用从实时电极位置跟踪获得的矢量测量的心脏再同步治疗优化
公开(公告)号：US08527049B2
公开(公告)日：2013-09-03
申请号：US12621373
申请日：2009-11-18
申请人： Steve Koh , Stuart Rosenberg , Kyungmoo Ryu , Michael Yang , Allen Keel
发明人： Steve Koh , Stuart Rosenberg , Kyungmoo Ryu , Michael Yang , Allen Keel
IPC分类号： A61N1/365 , A61B5/05
CPC分类号： A61N1/3627 , A61B5/0422 , A61B5/0452 , A61N1/36585 , A61N1/3682 , A61N1/3684 , A61N1/3686
摘要： An exemplary method includes selecting multiple electrodes located in a patient; acquiring position information during one or more cardiac cycles for the multiple electrodes where the acquiring includes using each of the electrodes for measuring one or more electrical potentials in an electrical localization field established in the patient; calculating one or more vector metrics based on the acquired position information for one or more vectors, each vector defined by two of the multiple electrodes; and analyzing the one or more vector metrics to assess cardiac performance during the one or more cardiac cycles. Various other methods, devices, systems, etc., are also disclosed.
摘要翻译：一种示例性方法包括选择位于患者体内的多个电极; 在所述多个电极的一个或多个心动周期期间获取位置信息，其中所述获取包括使用每个所述电极来测量在所述患者中建立的电定位场中的一个或多个电位; 基于所获取的一个或多个向量的位置信息来计算一个或多个矢量度量，每个矢量由所述多个电极中的两个限定; 以及分析所述一个或多个矢量度量以评估所述一个或多个心动周期期间的心脏性能。还公开了各种其它方法，装置，系统等。

65. 发明授权

US08509890B2 Capture verification and pacing adjustments for use with multisite left ventricular pacing 有权
标题翻译：捕获验证和起搏调整，用于多站点左心室起搏
公开(公告)号：US08509890B2
公开(公告)日：2013-08-13
申请号：US13091830
申请日：2011-04-21
申请人： Allen J. Keel , Kyungmoo Ryu , Stuart Rosenberg
发明人： Allen J. Keel , Kyungmoo Ryu , Stuart Rosenberg
IPC分类号： A61N1/362
CPC分类号： A61N1/3712 , A61N1/3684 , A61N1/3686
摘要： Various embodiments of the present invention are directed to, or are for use with, an implantable system including a lead having multiple electrodes implantable in a patient's left ventricular (LV) chamber. In accordance with an embodiment, the patients LV chamber is paced at first and second sites within the LV chamber using a programmed LV1-LV2 delay, wherein the LV1-LV2 delay is a programmed delay between when first and second pacing pulses are to be delivered respectively at the first and second sites within the LV chamber. Evoked responses to the first and second pacing pulses are monitored for, and one or more LV pacing parameter is/are adjusted and/or one or more backup pulse is/are delivered based on results of the monitoring.
摘要翻译：本发明的各种实施例涉及或可用于包括具有可植入患者左心室（LV）室中的多个电极的引线的可植入系统。根据实施例，患者LV腔室使用编程的LV1-LV2延迟在LV室内的第一和第二位置处起搏，其中LV1-LV2延迟是在第一和第二起搏脉冲要被传送之间的编程延迟分别在LV室内的第一和第二位置。基于监测结果监测对第一和第二起搏脉冲的诱发响应，并且调整一个或多个LV起搏参数和/或一个或多个备用脉冲。

66. 发明授权

US08401645B2 Electrode and lead stability indexes and stability maps based on localization system data 有权
标题翻译：基于定位系统数据的电极和铅稳定性指标和稳定性图
公开(公告)号：US08401645B2
公开(公告)日：2013-03-19
申请号：US12562003
申请日：2009-09-17
申请人： Stuart Rosenberg , Thao Thu Nguyen , Kyungmoo Ryu , Kjell Norén , Allen Keel , Wenbo Hou , Michael Yang
发明人： Stuart Rosenberg , Thao Thu Nguyen , Kyungmoo Ryu , Kjell Norén , Allen Keel , Wenbo Hou , Michael Yang
IPC分类号： A61N1/00 , A61B5/04
CPC分类号： A61N1/3702 , A61B5/042 , A61B5/0424 , A61B2560/0276 , A61N1/368 , A61N1/371
摘要： A method includes selecting an electrode located in a patient; acquiring position information with respect to time for the electrode where the acquiring uses the electrode for repeatedly measuring electrical potentials in an electrical localization field established in the patient; calculating a stability metric for the electrode based on the acquired position information with respect to time; and deciding if the selected electrode, as located in the patient, has a stable location for sensing biological electrical activity, for delivering electrical energy or for sensing biological electrical activity and delivering electrical energy. Position information may be acquired during one or both of intrinsic or paced activation of a heart and respective stability indexes calculated for each activation type.
摘要翻译：一种方法包括选择位于患者体内的电极; 获取相对于所述电极的时间的位置信息，其中所述电极在所述患者中建立的电定位场中使用所述电极重复测量电位; 基于获取的相对于时间的位置信息计算电极的稳定性度量; 并且确定位于患者体内的所选择的电极是否具有用于感测生物电活动的稳定位置，用于传递电能或用于感测生物电活动和递送电能。位置信息可以在心脏的固有或起搏激活和对于每种激活类型计算的各个稳定性指标的一个或两个期间获取。

67. 发明申请

US20130035738A1 METHODS AND SYSTEMS FOR DETERMINING PACING PARAMETERS BASED ON REPOLARIZATION INDEX 审中-公开
标题翻译：基于复合指数确定PAC参数的方法和系统
公开(公告)号：US20130035738A1
公开(公告)日：2013-02-07
申请号：US13197665
申请日：2011-08-03
申请人： Edward Karst , Kyungmoo Ryu , Stuart Rosenberg , Allen Keel
发明人： Edward Karst , Kyungmoo Ryu , Stuart Rosenberg , Allen Keel
IPC分类号： A61N1/368
CPC分类号： A61N1/3684 , A61N1/36507
摘要： Methods and systems are provided for determining pacing parameters for an implantable medical device (IMD). The methods and systems provide electrodes in the right atrium (RA), right ventricle (RV) and left ventricle (LV). The methods and systems sense RV cardiac signals and LV cardiac signals at an RV electrode and an LV electrode, respectively, over multiple cardiac cycles, to collect global activation information. The methods and systems identify a T-wave in the LV cardiac signal. The methods and systems calculate a repolarization index based at least in part on a timing of the T-wave identified in the LV cardiac signal. The methods and systems set at least one pacing parameter based on the repolarization index, wherein the at least one pacing parameter that is set represents at least one of an AV delay, an inter-ventricular interval and an intra-ventricular interval. Optionally, the methods and systems may deliver an RV pacing stimulus at the RV electrode such that the LV cardiac signal sensed thereafter includes the RV pacing stimulus followed by a T-wave. The methods and systems determine a waveform metric such as at least one of a QT interval, T-wave duration, and T-wave amplitude, and utilize the waveform metric to determine as the repolarization index.
摘要翻译：提供了用于确定可植入医疗装置（IMD）的起搏参数的方法和系统。方法和系统在右心房（RA），右心室（RV）和左心室（LV）中提供电极。方法和系统分别在多个心动周期上检测RV电极和LV电极上的RV心脏信号和LV心脏信号，以收集全局激活信息。方法和系统识别LV心脏信号中的T波。所述方法和系统至少部分地基于在LV心脏信号中识别的T波的定时来计算复极化指数。方法和系统基于复极度指数设置至少一个起搏参数，其中设置的至少一个起搏参数表示AV延迟，心室间间隔和心室间间隔中的至少一个。任选地，方法和系统可以在RV电极处递送RV起搏刺激，使得之后感测的LV心脏信号包括后跟T波的RV起搏刺激。方法和系统确定诸如QT间期，T波持续时间和T波幅度中的至少一个的波形度量，并且利用波形度量来确定复极化指数。

68. 发明申请

US20130030314A1 DEVICES, SYSTEMS AND METHODS TO PERFORM ARRHYTHMIA DISCRIMINATION BASED ON THE ATRIAL AND VENTRICULAR ACTIVATION TIMES 有权
标题翻译：基于ATRIAL和VENTRICULAR激活时间进行ARRHYTHMIA诊断的设备，系统和方法
公开(公告)号：US20130030314A1
公开(公告)日：2013-01-31
申请号：US13194747
申请日：2011-07-29
申请人： Allen J. Keel , Kyungmoo Ryu , Stuart Rosenburg
发明人： Allen J. Keel , Kyungmoo Ryu , Stuart Rosenburg
IPC分类号： A61B5/046 , A61N1/368 , A61B5/0464 , A61B5/0452
CPC分类号： A61N1/3962 , A61B5/0422 , A61B5/0452 , A61B5/0456 , A61B5/0464 , A61N1/3627 , A61N1/3684 , A61N1/3686
摘要： Described herein are implantable systems and devices, and methods for use therewith, that can be used to perform arrhythmia discrimination based on activation times. A plurality of different sensing vectors are used to obtain a plurality of IEGMs that collectively enable electrical activations to be detected in the left atrial (LA) chamber, the right atrial (RA) chamber, and at least one ventricular chamber of a patient's heart. For each of a plurality of cardiac cycles, there is a determination, based on the plurality of obtained IEGMs, of an LA activation time, an RA activation time, and a ventricular activation time. Arrhythmia discrimination is then performed based on the determined activation times.
摘要翻译：本文描述的是可植入的系统和装置及其使用的方法，其可用于基于活化时间执行心律失常鉴别。使用多个不同的感测向量来获得多个IEGM，其共同地使得能够在左心房（LA）腔室，右心房（RA）腔室和患者心脏的至少一个心室中检测电激活。对于多个心动周期中的每一个，基于多个获得的IEGM，确定LA激活时间，RA激活时间和心室激活时间。然后基于确定的活化时间进行心律失常鉴别。

69. 发明申请

US20120310296A1 DETERMINATION OF CARDIAC RESYNCHRONIZATION THERAPY SETTINGS 有权
标题翻译：心脏康复治疗方法的确定
公开(公告)号：US20120310296A1
公开(公告)日：2012-12-06
申请号：US13471167
申请日：2012-05-14
申请人： Kjell Noren , Anders Bjorling , Tomas Svensson , Sven-Erik Hedberg , Allen Keel , Stuart Rosenberg , Kyungmoo Ryu
发明人： Kjell Noren , Anders Bjorling , Tomas Svensson , Sven-Erik Hedberg , Allen Keel , Stuart Rosenberg , Kyungmoo Ryu
IPC分类号： A61N1/365
CPC分类号： A61N1/36507 , A61N1/3682 , A61N1/3684 , A61N1/37252
摘要： CRT settings for an implantable medical device are determined by applying pacing pulses to heart chambers of a scheme of different combinations of interchamber delays. A respective width parameter value representing an R or P wave width is determined for each such delay combination based on an ECG representing signal and the width parameter values are employed to estimate a parametric model defining the width parameter as a function of interchamber delays. Candidate interchamber delays that minimize the width parameter are determined from the parametric model and employed to determine optimal CRT settings. The technique provides an efficient way of finding optimal CRT settings when multiple pacing sites are available in a heart chamber.
摘要翻译：用于可植入医疗装置的CRT设置通过将不同组合的车间延迟的方案应用于心室来进行起搏脉冲来确定。基于ECG表示信号为每个这样的延迟组合确定表示R或P波宽的相应宽度参数值，并且使用宽度参数值来估计定义作为间歇延迟的函数的宽度参数的参数模型。从参数模型中确定最小化宽度参数的候选车间延迟，并用于确定最佳CRT设置。该技术提供了一种在心室中可用多个起搏部位时可以找到最佳CRT设置的有效方式。

70. 发明授权

US08285377B2 Pacing, sensing and other parameter maps based on localization system data 有权
标题翻译：基于定位系统数据的起搏，感应和其他参数图
公开(公告)号：US08285377B2
公开(公告)日：2012-10-09
申请号：US12553413
申请日：2009-09-03
申请人： Stuart Rosenberg , Kyungmoo Ryu , Allen Keel , Wenbo Hou , Thao Thu Nguyen , Steve Koh , Kjell Noren , Michael Yang
发明人： Stuart Rosenberg , Kyungmoo Ryu , Allen Keel , Wenbo Hou , Thao Thu Nguyen , Steve Koh , Kjell Noren , Michael Yang
IPC分类号： A61N1/362
CPC分类号： A61N1/3627 , A61N1/36521 , A61N1/36585 , A61N1/368 , A61N1/3684
摘要： An exemplary method generates a map of a pacing parameter, a sensing parameter or one or more other parameters based in part on location information acquired using a localization system configured to locate electrodes in vivo (i.e., within a patient's body). Various examples map capture thresholds, qualification criteria for algorithms, undesirable conditions and sensing capabilities. Various other methods, devices, systems, etc., are also disclosed.
摘要翻译：一种示例性方法基于部分地基于使用配置成在体内（即，在患者体内）定位电极的定位系统获取的位置信息来生成起搏参数，感测参数或一个或多个其它参数的图。各种示例映射捕获阈值，算法的资格标准，不良条件和感测能力。还公开了各种其它方法，装置，系统等。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式