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61. 发明申请

US20060247707A1 Cardiac signal template generation using waveform clustering 有权
公开(公告)号：US20060247707A1
公开(公告)日：2006-11-02
申请号：US11116544
申请日：2005-04-28
申请人： Scott Meyer , Yanting Dong
发明人： Scott Meyer , Yanting Dong
IPC分类号： A61N1/362
CPC分类号： A61B5/04525 , A61N1/371
摘要： Cardiac devices and methods using cardiac waveform clustering for template generation are described. A method of characterizing a cardiac response involves delivering pacing pulses to heart, the pulses having an energy greater than a capture threshold. Cardiac signals are sensed following the pulses. Cardiac signal characteristics, waveforms, and/or features are clustered into a plurality of clusters. A cardiac response template is formed using one or more of the plurality of clusters.

62. 发明授权

US08929983B2 Reverse hysteresis and mode switching for intermittent pacing therapy 有权
标题翻译：间歇性起搏治疗的反向滞后和模式切换
公开(公告)号：US08929983B2
公开(公告)日：2015-01-06
申请号：US12615050
申请日：2009-11-09
申请人： Shantha Arcot-Krishnamurthy , Gary T. Seim , Kent Lee , Yanting Dong , Allan C. Shuros , David L. Whitehouse
发明人： Shantha Arcot-Krishnamurthy , Gary T. Seim , Kent Lee , Yanting Dong , Allan C. Shuros , David L. Whitehouse
IPC分类号： A61N1/368 , A61N1/362
CPC分类号： A61N1/3627 , A61N1/3688
摘要： Cardioprotective pre-excitation pacing may be applied to stress or de-stress a particular myocardial region delivering of pacing pulses in a manner that causes a dyssynchronous contraction. Such dyssynchronous contractions are responsible for the desired cardioprotective effects of pre-excitation pacing. A method and device for applying reverse hysteresis and mode switching to the delivery of such cardioprotective pacing are described.
摘要翻译：心脏保护性预激发起搏可用于以导致同步收缩的方式对起搏脉冲递送的特定心肌区域应力或去应激。这种异常收缩负责预激励起搏的所需心脏保护作用。描述了一种用于将逆向滞后和模式切换应用于这种心脏保护起搏的递送的方法和装置。

63. 发明授权

US08768466B2 Method and apparatus to trend and optimize an implantable medical device using a patient management system 有权
标题翻译：使用患者管理系统趋势和优化可植入医疗装置的方法和装置
公开(公告)号：US08768466B2
公开(公告)日：2014-07-01
申请号：US12249856
申请日：2008-10-10
申请人： Yanting Dong , Xuan Wei , Ankur Garg , Quan Ni
发明人： Yanting Dong , Xuan Wei , Ankur Garg , Quan Ni
IPC分类号： A61N1/00 , A61N1/372 , G06F19/00 , A61N1/365
CPC分类号： A61N1/365 , A61N1/36585 , A61N1/37211 , A61N1/37264 , A61N1/37282 , G06F19/00 , G06F19/3418 , G06F19/3481
摘要： A remote external interface for an implantable cardiac function management device is configured to be communicatively coupled to the implantable cardiac function management device via a network to a local external interface and via telemetry between the local external interface and the implantable cardiac function management device. The remote external interface includes a communication circuit and a processor circuit. The communication circuit is configured to communicate with the implantable cardiac function management device. The processor circuit is configured to perform an analysis of physiologic data received from the implantable cardiac function management device in response to operation of the implantable cardiac function management device using a plurality of therapy control parameter sets. The processor circuit can be further configured to select a particular therapy control parameter set using the analysis.
摘要翻译：用于可植入心脏功能管理装置的远程外部接口被配置为通过网络通信地耦合到可植入心脏功能管理装置到本地外部接口并且经由本地外部接口和可植入心脏功能管理装置之间的遥测。远程外部接口包括通信电路和处理器电路。通信电路被配置为与可植入心脏功能管理装置进行通信。处理器电路被配置为响应于使用多个治疗控制参数组的可植入心脏功能管理装置的操作来执行从可植入心脏功能管理装置接收的生理数据的分析。处理器电路可以进一步配置为使用分析来选择特定的治疗控制参数集。

64. 发明授权

US08725261B2 Rate initialization and overdrive pacing for capture threshold testing 有权
标题翻译：速率初始化和超速起搏用于捕获阈值测试
公开(公告)号：US08725261B2
公开(公告)日：2014-05-13
申请号：US13306615
申请日：2011-11-29
申请人： Eric K. Enrooth , Sunipa Saha , Clayton S. Foster , Yanting Dong
发明人： Eric K. Enrooth , Sunipa Saha , Clayton S. Foster , Yanting Dong
IPC分类号： A61N1/362
CPC分类号： A61N1/371 , A61N1/3714
摘要： Approaches for rate initialization and overdrive pacing used during capture threshold testing are described. Cardiac cycles are detected and the cardiac events of a cardiac chamber that occur during the cardiac cycles are monitored. The number of intrinsic beats in the cardiac events is counted. Initialization for a capture threshold test involves maintaining a pre-test pacing rate for the capture threshold test if the number of intrinsic beats in the cardiac events is less than a threshold. The pacing rate is increased for the capture threshold test if the number of intrinsic beats in the cardiac events is greater than the threshold.
摘要翻译：描述捕获阈值测试期间使用的速率初始化和超速起搏的方法。检测到心脏周期，并监测在心脏周期期间发生的心室的心脏事件。计数心脏事件中的固有搏动次数。捕获阈值测试的初始化涉及如果心脏事件中的固有搏动次数小于阈值，则保持捕获阈值测试的预先测试起搏速率。如果心脏事件中的固有搏动次数大于阈值，则针对捕获阈值测试，起搏速率将增加。

65. 发明授权

US08600506B2 Systems and methods for collecting patient event information 有权
标题翻译：用于收集患者事件信息的系统和方法
公开(公告)号：US08600506B2
公开(公告)日：2013-12-03
申请号：US13568958
申请日：2012-08-07
申请人： Stephen J. Hahn , Yanting Dong , Haresh G. Sachanandani , Kenneth P. Hoyme , James O. Gilkerson
发明人： Stephen J. Hahn , Yanting Dong , Haresh G. Sachanandani , Kenneth P. Hoyme , James O. Gilkerson
IPC分类号： A61N1/00
CPC分类号： A61N1/37247 , A61N1/37258 , A61N1/3962
摘要： A method of and system for collecting patient event information is described, where the system includes an implantable medical device (IMD) and an external interface device. The external interface device is remote from the IMD and includes a communication module, a display device adapted to prompt a user of the system to select a reason for a particular transmission session and a user input device adapted to accept input indicating a selected reason.
摘要翻译：描述了用于收集患者事件信息的方法和系统，其中系统包括可植入医疗装置（IMD）和外部接口装置。外部接口设备远离IMD，并且包括通信模块，适于提示系统的用户选择特定传输会话的原因的显示设备和适于接受指示所选原因的输入设备的显示设备。

66. 发明授权

US08565879B2 Method and apparatus for pacing safety margin 有权
标题翻译：起搏安全幅度的方法和装置
公开(公告)号：US08565879B2
公开(公告)日：2013-10-22
申请号：US13071680
申请日：2011-03-25
申请人： Amy Jean Brisben , Shibaji Shome , Kenneth N. Hayes , Yanting Dong , Aaron R. McCabe , Scott A. Meyer , Kevin John Stalsberg
发明人： Amy Jean Brisben , Shibaji Shome , Kenneth N. Hayes , Yanting Dong , Aaron R. McCabe , Scott A. Meyer , Kevin John Stalsberg
IPC分类号： A61N1/08
CPC分类号： A61N1/36585 , A61N1/3712
摘要： An apparatus comprises a cardiac signal sensing circuit, a pacing therapy circuit, and a controller circuit. The controller circuit includes a safety margin calculation circuit. The controller circuit initiates delivery of pacing stimulation energy to the heart using a first energy level, changes the energy level by at least one of: a) increasing the energy from the first energy level until detecting that the pacing stimulation energy induces stable capture, or b) reducing the energy from the first energy level until detecting that the stimulation energy fails to induce capture, and continues changing the stimulation energy level until confirming stable capture or the failure of capture. The safety margin calculation circuit calculates a safety margin of pacing stimulation energy using at least one of a determined stability of a parameter associated with evoked response and a determined range of energy levels corresponding to stable capture or intermittent failure of capture.
摘要翻译：一种装置包括心脏信号感测电路，起搏治疗电路和控制器电路。控制器电路包括安全裕度计算电路。控制器电路使用第一能级开始向心脏传送起搏刺激能量，通过以下至少一种来改变能量水平：a）从第一能量级增加能量直到检测到起搏刺激能量引起稳定的捕获，或 b）减少来自第一能级的能量，直到检测到刺激能量不能诱导捕获，并且继续改变刺激能量水平，直到确认捕获稳定或捕获失败为止。安全裕度计算电路使用与诱发反应相关联的参数的确定的稳定性以及与捕获的稳定捕获或间歇性故障相对应的能量水平的确定范围中的至少一个来计算起搏刺激能量的安全裕度。

67. 发明授权

US08290591B2 Methods and systems for managing fusion and noise in cardiac pacing response classification 有权
标题翻译：用于管理心脏起搏反应分类中的融合和噪声的方法和系统
公开(公告)号：US08290591B2
公开(公告)日：2012-10-16
申请号：US12822480
申请日：2010-06-24
申请人： Kevin John Stalsberg , Yanting Dong , Scott A. Meyer , John Michael Voegele , Derek Daniel Bohn , Eric Keith Enrooth , Clayton Scott Foster , David William Yost
发明人： Kevin John Stalsberg , Yanting Dong , Scott A. Meyer , John Michael Voegele , Derek Daniel Bohn , Eric Keith Enrooth , Clayton Scott Foster , David William Yost
IPC分类号： A61N1/362
CPC分类号： A61N1/371 , A61B5/0452 , A61B5/7203 , A61B5/7217 , A61B5/7264
摘要： Methods and systems for detecting noise in cardiac pacing response classification processes involve determining that a cardiac response classification is possibly erroneous if unexpected signal content is detected. The unexpected signal content may comprise signal peaks that have polarity opposite to the polarity of peaks used to determine the cardiac response to pacing. Fusion/noise management processes include pacing at a relatively high energy level until capture is detected after a fusion, indeterminate, or possibly erroneous pacing response classification is made. The relatively high energy pacing pulses may be delivered until capture is detected or until a predetermined number of paces are delivered.
摘要翻译：用于检测心脏起搏反应分类过程中的噪声的方法和系统涉及如果检测到意外的信号内容，则确定心脏反应分类可能是错误的。意想不到的信号内容可以包括具有与用于确定对起搏的心脏反应的峰的极性相反的极性的信号峰。融合/噪声管理过程包括在相对高的能量级别进行起搏，直到在融合之后检测到捕获，不确定或可能错误的起搏响应分类。可以递送相对高的能量起搏脉冲，直到检测到捕获或直到传送预定数量的步数。

68. 发明申请

US20120165897A1 Rate Initialization and Overdrive Pacing for Capture Threshold Testing 有权
标题翻译：速率初始化和超速起搏用于捕获阈值测试
公开(公告)号：US20120165897A1
公开(公告)日：2012-06-28
申请号：US13306615
申请日：2011-11-29
申请人： Eric K. Enrooth , Sunipa Saha , Clayton Foster , Yanting Dong
发明人： Eric K. Enrooth , Sunipa Saha , Clayton Foster , Yanting Dong
IPC分类号： A61N1/37
CPC分类号： A61N1/371 , A61N1/3714
摘要： Approaches for rate initialization and overdrive pacing used during capture threshold testing are described. Cardiac cycles are detected and the cardiac events of a cardiac chamber that occur during the cardiac cycles are monitored. The number of intrinsic beats in the cardiac events is counted. Initialization for a capture threshold test involves maintaining a pre-test pacing rate for the capture threshold test if the number of intrinsic beats in the cardiac events is less than a threshold. The pacing rate is increased for the capture threshold test if the number of intrinsic beats in the cardiac events is greater than the threshold.
摘要翻译：描述捕获阈值测试期间使用的速率初始化和超速起搏的方法。检测到心脏周期，并监测在心脏周期期间发生的心室的心脏事件。计数心脏事件中的固有搏动次数。捕获阈值测试的初始化涉及如果心脏事件中的固有搏动次数小于阈值，则保持捕获阈值测试的预先测试起搏速率。如果心脏事件中的固有搏动次数大于阈值，则针对捕获阈值测试，起搏速率将增加。

69. 发明授权

US08145310B2 Non-captured intrinsic discrimination in cardiac pacing response classification 有权
标题翻译：心脏起搏反应分类中未被捕获的内在区别
公开(公告)号：US08145310B2
公开(公告)日：2012-03-27
申请号：US12217652
申请日：2008-07-07
申请人： Yanting Dong , Scott A. Meyer , Kevin John Stalsberg
发明人： Yanting Dong , Scott A. Meyer , Kevin John Stalsberg
IPC分类号： A61N1/37
CPC分类号： A61N1/371 , A61B5/04525
摘要： Cardiac devices and methods discriminate non-captured intrinsic beats during evoked response detection and classification by comparing the features of a post-pace cardiac signal with expected features associated with a non-captured response with intrinsic activation. Detection of a non-captured response with intrinsic activation may be based on the peak amplitude and timing of the cardiac signal. The methods may be used to discriminate between a fusion or capture beat and a non-captured intrinsic beat. Discriminating between possible cardiac responses to the pacing pulse may be useful, for example, during automatic capture verification and/or a capture threshold test.
摘要翻译：心脏装置和方法通过将后期心脏信号的特征与与未捕获的应答相关联的预期特征与内在激活进行比较来区分诱发反应检测和分类期间的非捕获固有搏动。利用内在激活的非捕获响应的检测可以基于心脏信号的峰值振幅和定时。该方法可以用于区分融合或捕获节拍和未捕获的固有节拍。对起搏脉冲的可能的心脏反应之间的区分可能是有用的，例如在自动捕获验证和/或捕获阈值测试期间。

70. 发明申请

US20120035489A1 RHYTHM DISCRIMINATION ENHANCEMENT - CHAMBER OF TACHY ORIGINATION 有权
标题翻译： RHYTHM歧视改进 - TACHY ORIGINATION室
公开(公告)号：US20120035489A1
公开(公告)日：2012-02-09
申请号：US13196469
申请日：2011-08-02
申请人： Yanting Dong , Deepa Mahajan , David L. Perschbacher
发明人： Yanting Dong , Deepa Mahajan , David L. Perschbacher
IPC分类号： A61B5/0464
CPC分类号： A61B5/0464 , A61B5/4836 , A61B5/7264 , A61N1/3962
摘要： An apparatus comprises an implantable cardiac signal sensing circuit and a controller circuit. The implantable cardiac signal sensing circuit provides a sensed depolarization signal from a ventricle and a sensed depolarization signal from an atrium. The controller circuit includes an onset detection circuit and a classification circuit. The onset detection circuit detects an onset episode that includes fast cardiac depolarizations and identifies a depolarization that initiates the onset episode. The classification circuit classifies the onset episode as supra-ventricular tachycardia (SVT) when the initiating onset episode is identified in the atrium and the number of atrial depolarizations is greater than or equal to the number of ventricular depolarizations during the onset episode, and as ventricular tachycardia (VT) when the initiating onset depolarization is identified in the ventricle and the number of ventricular depolarizations is greater than the number of atrial depolarizations during the onset episode.
摘要翻译：一种装置包括可植入心脏信号感测电路和控制器电路。可植入心脏信号感测电路提供来自心室的感测去极化信号和来自心房的感测去极化信号。控制器电路包括起始检测电路和分类电路。发作检测电路检测包括快速心脏去极化的发作发作，并识别启动发作发作的去极化。分类电路将起始发作分类为室上性心动过速（SVT），当在心房中鉴定起始发作发作时，心房去极化数大于或等于发作发作期间心室去极化数，以及心室在脑室中鉴定起始起始去极化并且心室去极化的数量大于发作期间心房去极化的数量时，心动过速（VT）。

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