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61. 发明申请

US20130027186A1 ULTRALOW-POWER IMPLANTABLE HUB-BASED WIRELESS IMPLANTABLE SENSOR COMMUNICATION 审中-公开
标题翻译：超低功耗可嵌入式无线可插拔传感器通信
公开(公告)号：US20130027186A1
公开(公告)日：2013-01-31
申请号：US13190737
申请日：2011-07-26
申请人： Can Cinbis , Michael A. Schugt , Richard J. O'Brien
发明人： Can Cinbis , Michael A. Schugt , Richard J. O'Brien
IPC分类号： H04Q5/22
CPC分类号： A61B5/0031 , A61B5/0002 , A61B5/0028 , A61B2560/0209 , A61N1/37211
摘要： Communication power in a medical device system is managed by providing power from a power supply to a communication circuit in a sensing device according to a first communication wake up mode set for a first time period and according to a second communication wake up mode set for a second time period. The second communication wake-up mode is established by a second device.
摘要翻译：医疗设备系统中的通信电力是根据第一时间段设定的第一通信唤醒模式和根据第二通信唤醒模式设置的，从电源向感测设备中的通信电路提供电力来管理的第二时间段第二通信唤醒模式由第二设备建立。

62. 发明申请

US20130018233A1 IMPLANTABLE TISSUE PERFUSION SENSING SYSTEM AND METHOD 有权
标题翻译：可植入组织渗透感应系统及方法
公开(公告)号：US20130018233A1
公开(公告)日：2013-01-17
申请号：US13612967
申请日：2012-09-13
申请人： Can Cinbis , James K. Carney
发明人： Can Cinbis , James K. Carney
IPC分类号： A61B5/0205 , A61B5/1455
CPC分类号： A61B5/1459 , A61B5/0059 , A61B5/024 , A61B5/046 , A61B5/0464 , A61B5/14542 , A61B5/7214 , A61N1/3925
摘要： A medical device for sensing cardiac events that includes a plurality of light sources capable of emitting light at a plurality of wavelengths, and a detector to detect the emitted light. A processor determines a plurality of light measurements in response to the emitted light detected by the detector, updates, for each of the plurality of wavelengths, a first normalization coefficient and a second normalization coefficient in response to the detected emitted light, and adjusts the determined plurality of light measurements in response to the first normalization coefficient and the second normalization coefficient.
摘要翻译：一种用于感测心脏事件的医疗装置，其包括能够发射多个波长的光的多个光源，以及检测器，用于检测发射的光。处理器响应于由检测器检测到的发射光来确定多个光测量，响应于检测到的发射光，针对多个波长中的每一个更新第一归一化系数和第二归一化系数，并且调整所确定的响应于第一归一化系数和第二归一化系数的多个光测量。

63. 发明授权

US08346332B2 Absolute calibrated tissue oxygen saturation and total hemoglobin volume fraction 有权
$Absolute calibrated tissue oxygen saturation and total hemoglobin volume fraction$
标题翻译：绝对校准组织氧饱和度和总血红蛋白体积分数
公开(公告)号：US08346332B2
公开(公告)日：2013-01-01
申请号：US12797811
申请日：2010-06-10
申请人： Jonathan L. Kuhn , David A. Anderson , Can Cinbis , Richard J. O'Brien , Yong K. Cho , Thomas J. Mullen , Avram Scheiner , Rodolphe P. Katra
发明人： Jonathan L. Kuhn , David A. Anderson , Can Cinbis , Richard J. O'Brien , Yong K. Cho , Thomas J. Mullen , Avram Scheiner , Rodolphe P. Katra
IPC分类号： A61B5/00
CPC分类号： A61N1/36557 , A61B5/1459 , A61N1/37258
摘要： A medical device for monitoring a patient condition includes a first combination of a light source and a light detector to emit light into a volume of tissue, detect light scattered by the volume of tissue, and provide a first output signal corresponding to an intensity of the detected light. A control module is coupled to the light source to control the light source to emit light at least four spaced-apart light wavelengths, and a monitoring module is coupled to the light detector to receive the output signal, compute a measure of tissue oxygenation in response to the light detector output signal, and detect tissue hypoxia using the measure of tissue oxygenation.
摘要翻译：用于监测患者状况的医疗装置包括光源和光检测器的第一组合，以将光发射到组织的体积中，检测由组织体积散射的光，并提供对应于组织的强度的第一输出信号检测到光。控制模块耦合到光源以控制光源发射至少四个间隔开的光波长的光，并且监测模块耦合到光检测器以接收输出信号，计算响应中组织氧合的量度到光检测器输出信号，并使用组织氧合的测量来检测组织缺氧。

64. 发明申请

US20120197350A1 COMMUNICATION DIPOLE FOR IMPLANTABLE MEDICAL DEVICE 有权
标题翻译：用于可植入医疗器械的通信用DIPOLE
公开(公告)号：US20120197350A1
公开(公告)日：2012-08-02
申请号：US13359886
申请日：2012-01-27
申请人： Jonathan P. Roberts , Can Cinbis , David J. Peichel , James C. Allan , James D. Reinke , Kamal Deep Mothilal , Erik Griswold , George Patras
发明人： Jonathan P. Roberts , Can Cinbis , David J. Peichel , James C. Allan , James D. Reinke , Kamal Deep Mothilal , Erik Griswold , George Patras
IPC分类号： A61N1/08
CPC分类号： A61N1/37205 , A61B5/0028 , A61B5/0031 , A61B5/0215 , A61B5/6876 , A61B5/6882 , A61B2562/0247 , A61N1/37217 , H04B13/005
摘要： This disclosure is directed to an implantable medical device having a communication dipole configured in accordance with the techniques described herein. In one example, the disclosure is directed to an implantable medical device comprising a housing that encloses at least a communication module, a first electrode of a communication dipole electrically coupled to the communication module and an electrically conductive fixation mechanism that is electrically coupled to a portion of the housing and wherein a portion of the fixation mechanism is configured to function as at least part of a second electrode of the communication dipole. The electrically conductive fixation mechanism includes a dielectric material that covers at least part of a surface of the fixation mechanism. The communication module is configured to transmit or receive a modulated signal between the first electrode and second electrode of the communication dipole.
摘要翻译：本公开涉及具有根据本文所描述的技术配置的通信偶极子的可植入医疗装置。在一个示例中，本公开涉及可植入医疗装置，其包括壳体，该壳体至少包围通信模块，电耦合到通信模块的通信偶极子的第一电极和电连接到通信模块的部分的导电固定机构并且其中所述固定机构的一部分被配置为用作所述通信偶极子的第二电极的至少一部分。导电固定机构包括覆盖固定机构的表面的至少一部分的电介质材料。通信模块被配置为在通信偶极子的第一电极和第二电极之间发送或接收调制信号。

65. 发明申请

US20120130208A1 COEFFICENT DETERMINATION FOR BLOOD OXYGEN SATURATION AND TOTAL HEMOGLOBIN CONCENTRATION INDICES 有权
标题翻译：血氧饱和度和总HEMOGLOBIN浓度指标的系数确定
公开(公告)号：US20120130208A1
公开(公告)日：2012-05-24
申请号：US12948884
申请日：2010-11-18
申请人： Jonathan L. Kuhn , Can Cinbis , David A. Anderson , James K. Carney
发明人： Jonathan L. Kuhn , Can Cinbis , David A. Anderson , James K. Carney
IPC分类号： A61B5/1459
CPC分类号： A61B5/1459 , A61B5/0075 , A61B5/14535 , A61B5/14542 , A61B5/14551 , A61B5/1495 , A61B5/4836
摘要： A first concentration of a chromophore corresponding to a measurement volume of an optical sensor is determined. A second concentration of the chromophore is obtained in the vicinity of the measurement volume corresponding to a change in at least one of a total concentration of the chromophore and a relative concentration of a first form of the chromophore to the total concentration of the chromophore in the measurement volume. Light remittance measurements including a first light wavelength and a second light wavelength are obtained corresponding to the first chromophore concentration and the second chromophore concentration. A coefficient for computing an index of a change in the chromophore concentration is computed using the difference between the first and second chromophore concentrations and the first and second light remittance measurements.
摘要翻译：确定对应于光学传感器的测量体积的发色团的第一浓度。在测量体积附近获得发色团的第二浓度，其对应于发色团的总浓度和发色团的第一形式的相对浓度与发色团的总浓度中的至少一个的变化相关测量体积。对应于第一发色团浓度和第二发色团浓度获得包括第一光波长和第二光波长的光汇率测量。使用第一和第二生色团浓度与第一和第二光汇率测量之间的差来计算计算发色团浓度变化指数的系数。

66. 发明申请

US20120109012A1 DISTANCE MEASUREMENT USING IMPLANTABLE ACOUSTIC TRANSDUCERS 有权
标题翻译：使用可移植的声学传感器进行距离测量
公开(公告)号：US20120109012A1
公开(公告)日：2012-05-03
申请号：US12914616
申请日：2010-10-28
申请人： Can Cinbis
发明人： Can Cinbis
IPC分类号： A61B5/103
CPC分类号： A61B5/1076 , A61B5/686 , A61B5/6869 , A61B8/56 , A61B2562/06 , A61N1/3627 , A61N1/36528 , A61N1/36578 , A61N1/368
摘要： Implantable systems and methods (e.g., using an implantable medical device) for measuring distance including a transmit/receive acoustic transducer implantable at a first location for transmitting and receiving acoustic signals, an echo acoustic transducer implantable at a second location for receiving the acoustic signal from the transmit/receive acoustic transducer and in response thereto transmitting a return echo signal to be received by the transmit/receive acoustic sensor, and a controller to control transmission of the acoustic signal from the transmit/receive acoustic transducer at a transmit time and determine a receive time corresponding to the time the transmit/receive acoustic transducer receives the return echo signal. The distance between the transmit/receive acoustic transducer and the echo acoustic transducer is determined as a function of the transmit time and the receive time.
摘要翻译：用于测量距离的可植入系统和方法（例如，使用可植入医疗装置），包括可在第一位置处植入以发射和接收声信号的发射/接收声学换能器，可在第二位置植入的用于接收来自发射/接收声换能器，并响应于此发送要由发射/接收声传感器接收的返回回波信号，以及控制器，用于在发射时间控制来自发射/接收声换能器的声信号的传输，并确定接收时间对应于发送/接收声换能器接收返回回波信号的时间。发射/接收声学换能器与回波声换能器之间的距离被确定为发射时间和接收时间的函数。

67. 发明申请

US20120108923A1 SYMMETRICALLY PACKAGED OPTICAL SENSORS FOR IMPLANTABLE MEDICAL DEVICES 有权
标题翻译：用于可植入医疗器械的对称包装光学传感器
公开(公告)号：US20120108923A1
公开(公告)日：2012-05-03
申请号：US12915984
申请日：2010-10-29
申请人： Can Cinbis , Jonathan L. Kuhn
发明人： Can Cinbis , Jonathan L. Kuhn
IPC分类号： A61B5/1459
CPC分类号： A61N1/056 , A61B5/1455 , A61B5/686 , A61N1/36557
摘要： Implantable medical devices and methods include an optical sensor that includes at least two optical sensor portions. The light emitting devices of the optical sensor are distributed among the at least two optical sensor portions.
摘要翻译：植入式医疗装置和方法包括包括至少两个光学传感器部分的光学传感器。光传感器的发光装置分布在至少两个光传感器部分中。

68. 发明申请

US20110166464A1 TELEMETRY-SYNCHRONIZED PHYSIOLOGICAL MONITORING AND THERAPY DELIVERY SYSTEMS 审中-公开
标题翻译：电话同步生理监测和治疗传递系统
公开(公告)号：US20110166464A1
公开(公告)日：2011-07-07
申请号：US13048951
申请日：2011-03-16
申请人： Brian B. Lee , Eric J. Panken , Can Cinbis , Gerard J. Hill , John J. Grevious
发明人： Brian B. Lee , Eric J. Panken , Can Cinbis , Gerard J. Hill , John J. Grevious
IPC分类号： A61B5/0402 , A61B5/0476 , A61N1/36
CPC分类号： A61N1/37288 , A61N1/3611 , A61N1/36135 , A61N1/36585 , Y10S128/903
摘要： A physiological monitoring or therapy delivery system includes autonomous, wirelessly linked, implantable devices located at different areas to sense physiologic signals and deliver therapy. At least one of the implantable devices can trigger synchronized action (e.g. data capture or therapy delivery) by other implantable devices via a telemetry link.
摘要翻译：生理监测或治疗递送系统包括位于不同区域的自主的，无线连接的可植入装置，以感测生理信号并递送治疗。可植入装置中的至少一个可以经由遥测链路触发其它可植入装置的同步动作（例如数据捕获或治疗传递）。

69. 发明申请

US20100317941A1 ABSOLUTE CALIBRATED TISSUE OXYGEN SATURATION AND TOTAL HEMOGLOBIN VOLUME FRACTION 有权
标题翻译：绝对的校准组织氧饱和度和总HEMOGLOBIN体积分数
公开(公告)号：US20100317941A1
公开(公告)日：2010-12-16
申请号：US12797811
申请日：2010-06-10
申请人： Jonathan L. Kuhn , David A. Anderson , Can Cinbis , Richard J. O'Brien , Yong K. Cho , Thomas J. Mullen , Avram Scheiner , Rodolphe P. Katra
发明人： Jonathan L. Kuhn , David A. Anderson , Can Cinbis , Richard J. O'Brien , Yong K. Cho , Thomas J. Mullen , Avram Scheiner , Rodolphe P. Katra
IPC分类号： A61B5/1455
CPC分类号： A61N1/36557 , A61B5/1459 , A61N1/37258
摘要： A medical device for monitoring a patient condition includes a first combination of a light source and a light detector to emit light into a volume of tissue, detect light scattered by the volume of tissue, and provide a first output signal corresponding to an intensity of the detected light. A control module is coupled to the light source to control the light source to emit light at least four spaced-apart light wavelengths, and a monitoring module is coupled to the light detector to receive the output signal, compute a measure of tissue oxygenation in response to the light detector output signal, and detect tissue hypoxia using the measure of tissue oxygenation.
摘要翻译：用于监测患者状况的医疗装置包括光源和光检测器的第一组合，以将光发射到组织的体积中，检测由组织体积散射的光，并提供对应于组织的强度的第一输出信号检测到光。控制模块耦合到光源以控制光源发射至少四个间隔开的光波长的光，并且监测模块耦合到光检测器以接收输出信号，计算响应中组织氧合的量度到光检测器输出信号，并使用组织氧合的测量来检测组织缺氧。

70. 发明申请

US20100317938A1 Device and Method for Monitoring of Absolute Oxygen Saturation and Tissue Hemoglobin Concentration 有权
标题翻译：用于监测绝对氧饱和度和组织血红蛋白浓度的装置和方法
公开(公告)号：US20100317938A1
公开(公告)日：2010-12-16
申请号：US12797744
申请日：2010-06-10
申请人： Jonathan L. Kuhn , Can Cinbis , James K. Carney
发明人： Jonathan L. Kuhn , Can Cinbis , James K. Carney
IPC分类号： A61B5/1455
CPC分类号： A61B5/14552 , A61B5/0084 , A61B5/14546 , A61B5/1459 , A61B5/7239 , A61N1/36557
摘要： A method and medical device for detecting signals that detects emitted light scattered by a volume of tissue delivered along a first pathway at a plurality of wavelengths to generate corresponding first detected light intensity output signals, detects emitted light scattered by the volume of tissue delivered along a second pathway different from the first pathway at a plurality of wavelengths to generate corresponding second detected light intensity output signals, determines whether a difference between the emitted light detected along the first pathway and the emitted light detected along the second pathway is greater than a predetermined threshold, and alters sensing by the device in response to the determining whether a difference is greater than the predetermined threshold.
摘要翻译：一种用于检测信号的方法和医疗装置，其检测由沿着第一路径以多个波长传送的组织体积散射的发射光，以产生相应的第一检测到的光强度输出信号，以检测由沿着在多个波长处与第一路径不同的第二路径以产生相应的第二检测光强度输出信号，确定沿着第一路径检测的发射光与沿着第二路径检测的发射光之间的差是否大于预定阈值并且改变响应于确定差异是否大于预定阈值的设备的感测。

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