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61. 发明授权

US4324801A Phenylguanidine acetylsalicylate compounds, process for production thereof, and pharmaceutical composition thereof 失效
标题翻译：苯基胍乙酰水杨酸酯化合物，其制备方法及其药物组合物
公开(公告)号：US4324801A
公开(公告)日：1982-04-13
申请号：US256165
申请日：1981-04-21
申请人： Meiki Matsuzaki , Hiroshi Okabe , Seishiro Tanaka , Takao Takiguchi , Kunikatsu Onodera
发明人： Meiki Matsuzaki , Hiroshi Okabe , Seishiro Tanaka , Takao Takiguchi , Kunikatsu Onodera
IPC分类号： C07C279/18 , C07C101/00 , A61K31/155 , A61K31/19 , A61K31/615 , C07C51/02 , C07C69/157
CPC分类号： C07C279/18
摘要： A compound of the formula ##STR1## wherein R.sub.1 is a member selected from the group consisting of a hydrogen atom, lower alkyl groups and lower alkoxy groups, R.sub.2 is a member selected from the group consisting of a hydrogen atom, halogen atoms, lower alkyl groups, a hydroxyl group and a trifluoromethyl group, R.sub.3 is a member selected from the group consisting of a hydrogen atom, halogen atoms, lower alkyl groups, lower alkoxy groups, an acetyl group, a carbamoyl group and lower alkyl carboxylate groups, and R.sub.4 represents a hydrogen atom or a halogen atom, a pharmaceutical composition comprising such a phenylguanidine acetylsalicylate compound as an active ingredient; and a process for production of aforesaid compound.
摘要翻译：式IMA的化合物，其中R 1为选自氢原子，低级烷基和低级烷氧基的成员，R 2为选自氢原子，卤素原子，低级烷基基团，羟基和三氟甲基，R3是选自氢原子，卤素原子，低级烷基，低级烷氧基，乙酰基，氨基甲酰基和低级烷基羧酸酯基的成员，R4和表示氢原子或卤素原子，作为活性成分的药物组合物，其包含乙酰水杨酸苯基胍化合物; 和上述化合物的制造方法。

62. 发明授权

US4107969A Hot strip coiling mandrel 失效
标题翻译：热带卷取芯棒
公开(公告)号：US4107969A
公开(公告)日：1978-08-22
申请号：US793355
申请日：1977-05-03
申请人： Hiroshi Okabe , Noboru Hase , Hitoshi Asai , Teruo Hiramatu
发明人： Hiroshi Okabe , Noboru Hase , Hitoshi Asai , Teruo Hiramatu
IPC分类号： B21C47/30 , B65H75/24
CPC分类号： B21C47/30 , B65H75/242
摘要： A hot strip coiling mandrel has a mechanism for engaging a plurality of equally circumferentially divided drum segments about a core shaft and for moving the core shaft or the drum segments relatively axially to thereby radially expand and collapse the drum defined by the segments. Top marks caused at the leading coil end of a hot strip by the use of such a mandrel are prevented by the provision of a buffer between the core shaft and each of the drum segments.
摘要翻译：热带卷绕芯轴具有用于使多个等同的周向分开的鼓部分绕着芯轴接合并且用于相对轴向地移动芯轴或鼓部分从而径向地膨胀和折叠由段限定的滚筒的机构。通过在芯轴和每个鼓段之间设置缓冲器来防止通过使用这种心轴在热带的引线圈端引起的顶痕。

63. 发明授权

US09326853B2 Retaining mechanisms for prosthetic valves 有权
标题翻译：人工瓣膜固定机构
公开(公告)号：US09326853B2
公开(公告)日：2016-05-03
申请号：US13188988
申请日：2011-07-22
申请人： Christopher Olson , Glen T. Rabito , Dustin P. Armer , Minh Ma , Devin Marr , Mark Huang , Hiroshi Okabe , Kevin Stewart , Alison S. Curtis , Philip P. Corso, Jr.
发明人： Christopher Olson , Glen T. Rabito , Dustin P. Armer , Minh Ma , Devin Marr , Mark Huang , Hiroshi Okabe , Kevin Stewart , Alison S. Curtis , Philip P. Corso, Jr.
IPC分类号： A61F2/24
CPC分类号： A61F2/243 , A61F2/2418 , A61F2/2427 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2220/0016 , A61F2220/005 , A61F2220/0075 , A61F2230/0054 , A61F2230/0076 , A61F2250/006
摘要： Disclosed herein are representative embodiments of methods, apparatus, and systems used to deliver a prosthetic heart valve to a deficient valve. In one embodiment, for instance, a support structure and an expandable prosthetic valve are advanced through the aortic arch of a patient using a delivery system. The support structure is delivered to a position on or adjacent to the surface of the outflow side of the aortic valve (the support structure defining a support-structure interior). The expandable prosthetic valve is delivered into the aortic valve and into the support-structure interior. The expandable prosthetic heart valve is expanded while the expandable prosthetic heart valve is in the support-structure interior and while the support structure is at the position on or adjacent to the surface of the outflow side of the aortic valve, thereby causing one or more native leaflets of the aortic valve to be frictionally secured between the support structure and the expanded prosthetic heart valve.
摘要翻译：这里公开了用于将假性心脏瓣膜递送到缺陷阀的方法，装置和系统的代表性实施例。在一个实施例中，例如，支撑结构和可扩张的假体瓣膜通过使用递送系统的患者的主动脉弓前进。支撑结构被传送到主动脉瓣（支撑结构限定支撑结构内部）的流出侧的表面上或邻近的位置。可膨胀假体瓣膜被输送到主动脉瓣并进入支撑结构内部。可扩张假体心脏瓣膜膨胀，而可扩张假体心脏瓣膜处于支撑结构内部，而支撑结构处于主动脉瓣的流出侧表面上或邻近主动脉瓣的流出侧的位置，从而导致一个或多个本机主动脉瓣的小叶被摩擦地固定在支撑结构和扩张的假体心脏瓣膜之间。

64. 发明授权

US08405469B2 Composite right/left (CRLH) couplers 有权
标题翻译：复合右/左（CRLH）耦合器
公开(公告)号：US08405469B2
公开(公告)日：2013-03-26
申请号：US13312328
申请日：2011-12-06
申请人： Tatsuo Itoh , Christophe Caloz , I-Hsiang Lin , Hiroshi Okabe
发明人： Tatsuo Itoh , Christophe Caloz , I-Hsiang Lin , Hiroshi Okabe
IPC分类号： H01P5/12 , H01P5/22
CPC分类号： H01P5/227
摘要： High-frequency couplers and coupling techniques are described utilizing artificial composite right/left-handed transmission line (CRLH-TL). Three specific forms of couplers are described; (1) a coupled-line backward coupler is described with arbitrary tight/loose coupling and broad bandwidth; (2) a compact enhanced-bandwidth hybrid ring coupler is described with increased bandwidth and decreased size; and (3) a dual-band branch-line coupler that is not limited to a harmonic relation between the bands. These variations are preferably implemented in a microstrip fabrication process and may use lumped-element components. The couplers and coupling techniques are directed at increasing the utility while decreasing the size of high-frequency couplers, and are suitable for use with separate coupler or couplers integrated within integrated devices.
摘要翻译：利用人造复合右/左传输线（CRLH-TL）描述高频耦合器和耦合技术。描述了三种具体形式的耦合器; （1）耦合线反向耦合器被描述为具有任意的紧/松耦合和宽带宽; （2）以增加的带宽和减小的尺寸描述紧凑的增强带宽混合环耦合器; 和（3）双频分支线耦合器，不限于频带之间的谐波关系。这些变化优选地在微带制造过程中实现，并且可以使用集总元件部件。耦合器和耦合技术旨在增加效用，同时降低高频耦合器的尺寸，并且适用于集成在集成器件内的单独的耦合器或耦合器。

65. 发明申请

US20120329074A1 MARKER FOR DETECTING GASTRIC CANCER AND METHOD FOR DETECTING GASTRIC CANCER 有权
标题翻译：用于检测胃癌的标记物和用于检测胃癌的方法
公开(公告)号：US20120329074A1
公开(公告)日：2012-12-27
申请号：US13582316
申请日：2011-03-03
申请人： Yoshinori Tanaka , Satoko Kanamori , Michimoto Kobayashi , Giman Jung , Yoshiharu Sakai , Hiroshi Okabe
发明人： Yoshinori Tanaka , Satoko Kanamori , Michimoto Kobayashi , Giman Jung , Yoshiharu Sakai , Hiroshi Okabe
IPC分类号： G01N33/574
CPC分类号： G01N33/57446 , G01N2333/4712
摘要： It is intended to provide a method for detecting gastric cancer, which is low invasive to a human test subject and has high detection sensitivity and accuracy. The present invention provides a method comprising measuring in vitro the amount of COTL1 protein, a variant thereof, and/or a fragment thereof in a body fluid sample derived from a human test subject, and detecting the presence or absence of gastric cancer affecting the test subject on the basis of the amount, and a kit for gastric cancer diagnosis comprising an antibody capable of specifically binding to the protein.
摘要翻译：目的在于提供一种检测对人体检测对象侵袭性低，检测灵敏度高，准确度高的胃癌的方法。本发明提供了一种方法，其包括在源自人类受检者的体液样品中体外测量COTL1蛋白，其变体和/或其片段的量，并检测影响测试的胃癌的存在或不存在基于该量的受试者，以及包含能够特异性结合蛋白质的抗体的胃癌诊断试剂盒。

66. 发明申请

US20120139659A1 COMPOSITE RIGHT/LEFT (CRLH) COUPLERS 有权
标题翻译：复合右/左（CRLH）联轴器
公开(公告)号：US20120139659A1
公开(公告)日：2012-06-07
申请号：US13312328
申请日：2011-12-06
申请人： Tatsuo Itoh , Christophe Caloz , I-Hsiang Lin , Hiroshi Okabe
发明人： Tatsuo Itoh , Christophe Caloz , I-Hsiang Lin , Hiroshi Okabe
IPC分类号： H01P5/16
CPC分类号： H01P5/227
摘要： High-frequency couplers and coupling techniques are described utilizing artificial composite right/left-handed transmission line (CRLH-TL). Three specific forms of couplers are described; (1) a coupled-line backward coupler is described with arbitrary tight/loose coupling and broad bandwidth; (2) a compact enhanced-bandwidth hybrid ring coupler is described with increased bandwidth and decreased size; and (3) a dual-band branch-line coupler that is not limited to a harmonic relation between the bands. These variations are preferably implemented in a microstrip fabrication process and may use lumped-element components. The couplers and coupling techniques are directed at increasing the utility while decreasing the size of high-frequency couplers, and are suitable for use with separate coupler or couplers integrated within integrated devices.
摘要翻译：利用人造复合右/左传输线（CRLH-TL）描述高频耦合器和耦合技术。描述了三种具体形式的耦合器; （1）耦合线反向耦合器被描述为具有任意的紧/松耦合和宽带宽; （2）以增加的带宽和减小的尺寸描述紧凑的增强带宽混合环耦合器; 和（3）双频分支线耦合器，不限于频带之间的谐波关系。这些变化优选地在微带制造过程中实现，并且可以使用集总元件部件。耦合器和耦合技术旨在增加效用，同时降低高频耦合器的尺寸，并且适用于集成在集成器件内的单独的耦合器或耦合器。

67. 发明授权

US07739992B2 Starting system for small-sized engine 有权
标题翻译：小型发动机起动系统
公开(公告)号：US07739992B2
公开(公告)日：2010-06-22
申请号：US12309041
申请日：2007-06-18
申请人： Hiroshi Okabe
发明人： Hiroshi Okabe
IPC分类号： F02N11/14 , F02N5/02 , F02N3/02
CPC分类号： F02N11/12 , F02N3/02 , F02N15/006 , F02N2250/08
摘要： A starting system for a small-sized engine is described which achieves downsizing, light-weight, and cost reduction of the system, prevents entry of dust or foreign substances at the time of assembly, and achieves easy assembly of a motor. The starting system for a small-sized engine includes a recoil starting system and a motor starting system integrated in a starter case, in which the motor starting system has a configuration in which a pinion is mounted on an output shaft of a reducer motor by an one-way clutch of a needle bearing and the pinion is engaged with a starting gear 6 of an engine, and the starter case has a configuration in which an inner lid is secured to a crankcase of the engine together by a screw and the inner lid has a joint portion with respect to the crankcase and a mounting seat for the reducer motor on the outside thereof.
摘要翻译：描述了一种小型发动机的启动系统，其实现了系统的小型化，轻量化和降低成本，防止组装时灰尘或异物进入，并且实现了马达的容易组装。小型发动机的启动系统包括一个后起动系统和集成在起动机壳体中的电动机启动系统，其中电动机启动系统具有一个构造，其中小齿轮通过一个减速电动机安装在减速电动机的输出轴上滚针轴承的单向离合器和小齿轮与发动机的起动齿轮6接合，起动器壳体具有这样的构造，其中内盖通过螺钉固定在发动机的曲轴箱上，内盖具有相对于曲轴箱的接合部分和用于其外侧的减速电机的安装座。

68. 发明授权

US07667555B2 Composite right/left handed (CRLH) branch-line couplers 有权
标题翻译：复合右/左手（CRLH）分支线耦合器
公开(公告)号：US07667555B2
公开(公告)日：2010-02-23
申请号：US12122371
申请日：2008-05-16
申请人： Tatsuo Itoh , Christophe Caloz , I-Hsiang Lin , Hiroshi Okabe
发明人： Tatsuo Itoh , Christophe Caloz , I-Hsiang Lin , Hiroshi Okabe
IPC分类号： H01P5/12 , H01P5/22
CPC分类号： H01P5/227
摘要： High-frequency couplers and coupling techniques are described utilizing artificial composite right/left-handed transmission line (CRLH-TL). Three specific forms of couplers are described; (1) a coupled-line backward coupler is described with arbitrary tight/loose coupling and broad bandwidth; (2) a compact enhanced-bandwidth hybrid ring coupler is described with increased bandwidth and decreased size; and (3) a dual-band branch-line coupler that is not limited to a harmonic relation between the bands. These variations are preferably implemented in a microstrip fabrication process and may use lumped-element components. The couplers and coupling techniques are directed at increasing the utility while decreasing the size of high-frequency couplers, and are suitable for use with separate coupler or couplers integrated within integrated devices.
摘要翻译：利用人造复合右/左传输线（CRLH-TL）描述高频耦合器和耦合技术。描述了三种具体形式的耦合器; （1）耦合线反向耦合器被描述为具有任意的紧/松耦合和宽带宽; （2）以增加的带宽和减小的尺寸描述紧凑的增强带宽混合环耦合器; 和（3）双频分支线耦合器，不限于频带之间的谐波关系。这些变化优选地在微带制造工艺中实现，并且可以使用集总元件部件。耦合器和耦合技术旨在增加效用，同时降低高频耦合器的尺寸，并且适用于集成在集成器件内的单独的耦合器或耦合器。

69. 发明授权

US07554048B2 Ultrasonic treatment switch device and medical device switch attachment system 失效
标题翻译：超声波治疗开关装置和医疗器械开关附件系统
公开(公告)号：US07554048B2
公开(公告)日：2009-06-30
申请号：US11446879
申请日：2006-06-05
申请人： Hiroshi Okabe , Yoshitaka Fujii
发明人： Hiroshi Okabe , Yoshitaka Fujii
IPC分类号： H01H9/06
CPC分类号： A61B17/320092 , A61B2017/00367 , A61B2017/0046 , A61B2017/291
摘要： An ultrasonic treatment switch device includes an adapter, a switch, a switch fixing portion and an adapter fixing portion. The adapter is connected to a power source and having a hand piece fixing portion detachably attached to a hand piece having an ultrasonic transducer. The switch is connected to the power source and causes an electric signal to be output from the power source so that the ultrasonic transducer generates ultrasonic vibrations. The switch fixing portion is provided in the switch and detachably attached to the adapter. The adapter fixing portion is provided in the adapter. The switch fixing portion is attached to the adapter fixing portion.
摘要翻译：超声处理开关装置包括适配器，开关，开关固定部和适配器固定部。适配器连接到电源并且具有可拆卸地附接到具有超声波换能器的手持件上的手持件固定部。开关连接到电源，并且从电源输出电信号，使得超声波换能器产生超声波振动。开关固定部设置在开关中并可拆卸地附接到适配器。适配器固定部设置在适配器中。开关固定部附接到适配器固定部。

70. 发明申请

US20090114181A1 Starting system for small-sized engine 有权
标题翻译：小型发动机起动系统
公开(公告)号：US20090114181A1
公开(公告)日：2009-05-07
申请号：US12309041
申请日：2007-06-18
申请人： Hiroshi Okabe
发明人： Hiroshi Okabe
IPC分类号： F02N3/02
CPC分类号： F02N11/12 , F02N3/02 , F02N15/006 , F02N2250/08
摘要： A starting system for a small-sized engine is described which achieves downsizing, light-weight, and cost reduction of the system, prevents entry of dust or foreign substances at the time of assembly, and achieves easy assembly of a motor. The starting system for a small-sized engine includes a recoil starting system and a motor starting system integrated in a starter case, in which the motor starting system has a configuration in which a pinion is mounted on an output shaft of a reducer motor by an one-way clutch of a needle bearing and the pinion is engaged with a starting gear 6 of an engine, and the starter case has a configuration in which an inner lid is secured to a crankcase of the engine together by a screw and the inner lid has a joint portion with respect to the crankcase and a mounting seat for the reducer motor on the outside thereof.
摘要翻译：描述了一种小型发动机的启动系统，其实现了系统的小型化，轻量化和降低成本，防止组装时灰尘或异物进入，并且实现了马达的容易组装。小型发动机的启动系统包括一个后起动系统和集成在起动机壳体中的电动机启动系统，其中电动机启动系统具有一个构造，其中小齿轮通过一个减速电动机安装在减速电动机的输出轴上滚针轴承的单向离合器和小齿轮与发动机的起动齿轮6接合，起动器壳体具有这样的构造，其中内盖通过螺钉固定在发动机的曲轴箱上，内盖具有相对于曲轴箱的接合部分和用于其外侧的减速电机的安装座。

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