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61. 发明授权

US3985390A Tunnel excavator 失效
标题翻译：隧道挖掘机
公开(公告)号：US3985390A
公开(公告)日：1976-10-12
申请号：US559539
申请日：1975-03-18
申请人： Chiaki Kojima , Hiroshi Ohta , Hidekazu Aoki
发明人： Chiaki Kojima , Hiroshi Ohta , Hidekazu Aoki
IPC分类号： E21D9/10 , E21D11/36
CPC分类号： E21D9/1053
摘要： Tunnel excavator for forming an upper half annular hollow space in the solid earth. The excavator has an arch shaped shield provided with a plurality of chambers in which excavating machines are located. Each of the excavating machines is swingably supported in the respective chamber and gripper means for securely abutting against the outer and inner surfaces of the solid earth formed by the upper half annular hollow space is located in each of the chambers. Thrust generating means is connected between the respective excavating machines and the respective gripper means so that the excavating machines can be advanced by the action of the thrust generating means when the gripper means is actuated to abut against the earth.
摘要翻译：隧道挖掘机，用于在固体地球上形成上半部环形空心空间。挖掘机具有设置有挖掘机所在的多个室的拱形罩。每个挖掘机可摆动地支撑在相应的腔室中，用于牢固地抵靠由上半环形中空空间形成的固体地球的外表面和内表面的夹持装置位于每个腔室中。推力发生装置连接在相应的挖掘机和相应的夹具装置之间，使得当夹紧装置被致动以抵靠地球时，挖掘机可以通过推力发生装置的作用而前进。

62. 发明授权

US09312521B2 Cell, assembled battery, and battery-mounted device 有权
标题翻译：电池，组装电池和电池安装装置
公开(公告)号：US09312521B2
公开(公告)日：2016-04-12
申请号：US14241808
申请日：2011-08-29
申请人： Hiroshi Ohta
发明人： Hiroshi Ohta
IPC分类号： H01M2/06 , H01M2/30 , H01M2/02 , H01M2/22 , H01M2/24 , H01M2/26
CPC分类号： H01M2/06 , H01M2/02 , H01M2/022 , H01M2/024 , H01M2/22 , H01M2/24 , H01M2/26 , H01M2/30 , H01M2/305
摘要： Disclosed is a cell including: a closed-end tubular case for accommodating a power generation element; a lid for the case; a terminal electrode disposed outside of the case and used for connection with another cell; an extraction electrode passing through the lid and used to extract power of the power generation element to the outside of the case; and a stepped connection electrode disposed outside of the case, the stepped connection electrode having a first flat portion to which the terminal electrode is connected and a second flat portion which is located at a level different from the level of the first flat portion and to which the extraction electrode is connected. The first and second flat portions have regions overlapping each other as viewed in a direction orthogonal to the thickness of the first and second flat portions.
摘要翻译：公开了一种电池，包括：用于容纳发电元件的封闭端管状壳体; 一箱盖; 端子电极，设置在壳体的外部并用于与另一个电池连接; 通过所述盖并用于将所述发电元件的功率提取到所述壳体的外部的引出电极; 以及设置在所述壳体的外侧的阶梯状连接电极，所述阶梯状连接电极具有与所述端子电极连接的第一平坦部，以及位于与所述第一平坦部的高度不同的水平面的第二平坦部，引出电极连接。当与第一和第二平坦部分的厚度正交的方向观察时，第一和第二平坦部分具有彼此重叠的区域。

63. 发明授权

US08623898B2 Glycine transporter inhibiting substances 失效
标题翻译：甘氨酸转运蛋白抑制物质
公开(公告)号：US08623898B2
公开(公告)日：2014-01-07
申请号：US13257258
申请日：2010-03-19
申请人： Akito Yasuhara , Shuji Yamamoto , Hiroshi Ohta , Yoshihisa Shirasaki , Kazunari Sakagami , Masato Hayashi , Tsuyoshi Shibata , Youichi Shimazaki , Yuko Araki , Kumi Abe , Xiang-Min Sun
发明人： Akito Yasuhara , Shuji Yamamoto , Hiroshi Ohta , Yoshihisa Shirasaki , Kazunari Sakagami , Masato Hayashi , Tsuyoshi Shibata , Youichi Shimazaki , Yuko Araki , Kumi Abe , Xiang-Min Sun
IPC分类号： C07D471/04 , C07D405/12 , C07D409/12 , C07D405/14 , A01N43/64 , A01N43/50 , A61K31/41
CPC分类号： C07D471/04 , C07D405/12 , C07D405/14 , C07D409/12
摘要： The present invention aims to provide novel compounds of formula [I] or pharmaceutically acceptable salts thereof that are based on a glycine uptake inhibiting action and which are useful in the prevention or treatment of such diseases as schizophrenia, Alzheimer's disease, cognitive dysfunction, dementia, anxiety disorders (generalized anxiety disorder, panic disorder, obsessive-compulsory disorder, social anxiety disorder, posttraumatic stress disorder, specific phobia, acute stress disorder, etc.), depression, drug addiction, spasm, tremor, and sleep disorder:
摘要翻译：本发明旨在提供基于甘氨酸摄取抑制作用的新颖的式[I]化合物或其药学上可接受的盐，其可用于预防或治疗精神分裂症，阿尔茨海默病，认知功能障碍，痴呆，焦虑症（广泛性焦虑障碍，恐慌症，强迫症，社会焦虑症，创伤后应激障碍，特定恐惧症，急性应激障碍等），抑郁症，药物成瘾，痉挛，震颤和睡眠障碍：

64. 发明申请

US20130184460A1 GLYCINE TRANSPORTER INHIBITING SUBSTANCES 有权
标题翻译：糖果运输保护物质
公开(公告)号：US20130184460A1
公开(公告)日：2013-07-18
申请号：US13823574
申请日：2011-09-16
申请人： Minoru Moriya , Akito Yasuhara , Kazunari Sakagami , Hiroshi Ohta , Kumi Abe , Shuji Yamamoto , Yuko Araki , Hiroki Urabe , Xiang-Min Sun
发明人： Minoru Moriya , Akito Yasuhara , Kazunari Sakagami , Hiroshi Ohta , Kumi Abe , Shuji Yamamoto , Yuko Araki , Hiroki Urabe , Xiang-Min Sun
IPC分类号： C07D405/14 , C07D403/12 , C07D401/12
CPC分类号： C07D405/14 , C07D233/90 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04
摘要： The present invention aims to provide novel compounds of formula [I] or pharmaceutically acceptable salts thereof that are based on a glycine uptake inhibiting action and which are useful in the prevention or treatment of such diseases as schizophrenia, Alzheimer's disease, cognitive dysfunction, dementia, anxiety disorders (generalized anxiety disorder, panic disorder, obsessive-compulsive disorder, social anxiety disorder, posttraumatic stress disorder, specific phobia, acute stress disorder, etc.), depression, drug addiction, spasm, tremor, pain, and sleep disorder:
摘要翻译：本发明旨在提供基于甘氨酸摄取抑制作用的新颖的式[I]化合物或其药学上可接受的盐，其可用于预防或治疗精神分裂症，阿尔茨海默病，认知功能障碍，痴呆，焦虑障碍（广泛性焦虑症，惊恐障碍，强迫症，社会焦虑症，创伤后应激障碍，特定恐惧症，急性应激障碍等），抑郁症，药物成瘾，痉挛，震颤，疼痛和睡眠障碍：

65. 发明授权

US08350060B2 2-amino-bicyclo[3.1.0] hexane-2, 6-dicarboxylic ester derivative 失效
标题翻译： 2-氨基 - 双环[3.1.0]己烷-2,6-二羧酸酯衍生物
公开(公告)号：US08350060B2
公开(公告)日：2013-01-08
申请号：US13227942
申请日：2011-09-08
申请人： Akito Yasuhara , Kazunari Sakagami , Hiroshi Ohta , Atsuro Nakazato
发明人： Akito Yasuhara , Kazunari Sakagami , Hiroshi Ohta , Atsuro Nakazato
IPC分类号： C07D307/87 , A61K31/34
CPC分类号： C07C229/50 , C07D307/88
摘要： A drug effective for the treatment and prevention of psychiatric disorders such as schizophrenia, anxiety and related ailments thereof, depression, bipolar disorder and epilepsy. The drug antagonizes the action of group II metabotropic glutamate receptors and shows high activity in oral administrationA 2-amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic ester derivative represented by formula [I] [wherein R1 and R2 are identical or different, and each represents a hydrogen atom, a C1-10alkyl group or the like; X represents a hydrogen atom or a fluorine atom; Y represents —OCHR3R4 or the like (wherein R3 and R4 are identical or different, and each represents a hydrogen atom, a C1-10alkyl group or the like; and n represents integer 1 or 2)], a pharmaceutically acceptable salt thereof or a hydrate thereof.
摘要翻译：一种有效治疗和预防精神疾病如精神分裂症，焦虑及其相关疾病，抑郁症，双相情感障碍和癫痫的药物。该药物拮抗II型代谢型谷氨酸受体的作用，并且在口服给药中表现出高活性。由式[I]表示的2-氨基 - 双环[3.1.0]己烷-2,6-二羧酸酯衍生物[其中R1和R2为相同或不同，并且各自表示氢原子，C 1-10烷基等; X表示氢原子或氟原子; Y表示-OCHR 3 R 4等（其中R 3和R 4相同或不同，并且各自表示氢原子，C 1-10烷基等; n表示1或2的整数）]，其药学上可接受的盐或水合物。

66. 发明授权

US08193176B2 Phenylpyrazole derivatives 有权
公开(公告)号：US08193176B2
公开(公告)日：2012-06-05
申请号：US12951978
申请日：2010-11-22
申请人： Toshio Nakamura , Makoto Tatsuzuki , Dai Nozawa , Tomoko Tamita , Seiji Masuda , Hiroshi Ohta , Shuhei Kashiwa , Aya Fujino , Shigeyuki Chaki , Toshiharu Shimazaki
发明人： Toshio Nakamura , Makoto Tatsuzuki , Dai Nozawa , Tomoko Tamita , Seiji Masuda , Hiroshi Ohta , Shuhei Kashiwa , Aya Fujino , Shigeyuki Chaki , Toshiharu Shimazaki
IPC分类号： A61K31/5377 , A61K31/4155 , A61K31/397 , A61K31/553 , A61K31/496
CPC分类号： C07D231/14 , C07D231/40 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D403/14 , C07D413/04 , C07D413/14
摘要： The present invention provides a prophylactic or therapeutic agent for dementia, Alzheimer's disease, attention-deficit hyperactivity disorder, schizophrenia, eating disorders, obesity, diabetes, hyperlipidemia, sleep disorders, narcolepsy, sleep apnea syndrome, circadian rhythm disorder, depression, allergic rhinitis or other diseases.A phenylpyrazole derivative represented by formula (1) or a pharmaceutically acceptable salt thereof: {wherein R1 and R2, which may be the same or different, each represent C1-C6 alkyl or C3-C8 cycloalkyl, or R1 and R2 are attached to each other together with their adjacent nitrogen atom to form a 4- to 7-membered saturated heterocyclic ring (wherein said saturated heterocyclic ring may be substituted with halogen or C1-C6 alkyl), n represents an integer of 0 to 2, T represents a hydrogen atom, halogen or C1-C6 alkyl, and R represents formula (I): or the like}.

67. 发明授权

US08039647B2 2-amino-bicyclo (3.1.0) hexane-2,6-dicarboxylic ester derivative 失效
标题翻译： 2-氨基 - 双环（3.1.0）己烷-2,6-二羧酸酯衍生物
公开(公告)号：US08039647B2
公开(公告)日：2011-10-18
申请号：US12511482
申请日：2009-07-29
申请人： Akito Yasuhara , Kazunari Sakagami , Hiroshi Ohta , Atsuro Nakazato
发明人： Akito Yasuhara , Kazunari Sakagami , Hiroshi Ohta , Atsuro Nakazato
IPC分类号： C07D317/08
CPC分类号： C07C229/50 , C07D307/88
摘要： A drug effective for the treatment and prevention of psychiatric disorders such as schizophrenia, anxiety and related ailments thereof, depression, bipolar disorder and epilepsy. The drug antagonizes the action of group II metabotropic glutamate receptors and shows high activity in oral administrationA 2-amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic ester derivative represented by formula [I] [wherein R1 and R2 are identical or different, and each represents a hydrogen atom, a C1-10alkyl group or the like; X represents a hydrogen atom or a fluorine atom; Y represents —OCHR3R4 or the like (wherein R3 and R4 are identical or different, and each represents a hydrogen atom, a C1-10alkyl group or the like; and n represents integer 1 or 2)], a pharmaceutically acceptable salt thereof or a hydrate thereof.
摘要翻译：一种有效治疗和预防精神疾病如精神分裂症，焦虑及其相关疾病，抑郁症，双相情感障碍和癫痫的药物。该药物拮抗II型代谢型谷氨酸受体的作用，并且在口服给药中表现出高活性。由式[I]表示的2-氨基 - 双环[3.1.0]己烷-2,6-二羧酸酯衍生物[其中R1和R2为相同或不同，并且各自表示氢原子，C 1-10烷基等; X表示氢原子或氟原子; Y表示-OCHR 3 R 4等（其中R 3和R 4相同或不同，各自表示氢原子，C 1-10烷基等; n表示1或2的整数）]，其药学上可接受的盐或水合物。

68. 发明授权

US07999989B2 Photochromic film, photochromic lens comprising the same, and method of manufacturing photochromic lens 有权
标题翻译：光致变色膜，包含其的光致变色镜片和制造光致变色镜片的方法
公开(公告)号：US07999989B2
公开(公告)日：2011-08-16
申请号：US12307057
申请日：2007-05-31
申请人： Osamu Asai , Eiichi Yajima , Hiroshi Ohta
发明人： Osamu Asai , Eiichi Yajima , Hiroshi Ohta
IPC分类号： G02F1/00
CPC分类号： G02B1/10 , B29D11/0073 , C09K9/02 , C09K2211/1007 , C09K2211/1011 , C09K2211/1033 , C09K2211/1088 , G02B1/11 , G02B1/14 , G02B5/23
摘要： The present invention relates to a photochromic film comprising a photochromic dye and a resin component. The photochromic film has a nanoindentation hardness of equal to or greater than 800 nm on at least one of surfaces, surface A, thereof. The present invention further relates to a method of manufacturing a photochromic lens. The method of manufacturing a photochromic lens of the present invention comprises forming a photochromic film having a nanoindentation hardness ranging from 500 to 5000 nm on an outermost surface thereof as well as having a smaller nanoindentation hardness on a surface facing a first mold than that on the outermost surface by coating a photochromic liquid comprising a photochromic dye and a curable component on one surface of the first mold for formation of one of surfaces of a lens and subjecting the photochromic liquid to curing treatment, and a photochromic lens comprising a photochromic film on a lens substrate is obtained by means of the above first mold.
摘要翻译：本发明涉及包含光致变色染料和树脂成分的光致变色膜。该光致变色膜在其至少一个表面A上具有等于或大于800nm的纳米压痕硬度。本发明还涉及一种制造光致变色透镜的方法。制造本发明的光致变色透镜的方法包括在其最外表面上形成具有500-5000nm的纳米压痕硬度的光致变色膜，并且在面向第一模具的表面上具有比在第一模具上的纳米压痕硬度小通过在第一模具的一个表面上涂覆包含光致变色染料和可固化组分的光致变色液体，以形成透镜表面之一并使该光致变色液体进行固化处理，以及包含光致变色膜的光致变色透镜透镜基板通过上述第一模具获得。

69. 发明申请

US20110116964A1 SUPPORT MEMBER FOR HIGH-TEMPERATURE HEAT-TREATED METAL MOLDING OBJECT AND PROCESS FOR PRODUCTION THEREOF 审中-公开
标题翻译：高温热处理金属成型对象及其生产工艺支持会员
公开(公告)号：US20110116964A1
公开(公告)日：2011-05-19
申请号：US13014051
申请日：2011-01-26
申请人： Naohiro Sonobe , Hiroshi Ohta , Hideaki Sato , Yo Otani
发明人： Naohiro Sonobe , Hiroshi Ohta , Hideaki Sato , Yo Otani
IPC分类号： B22F3/16
CPC分类号： C04B35/532 , B22F2003/1042 , C04B2235/3217 , C04B2235/48 , C04B2235/528 , C04B2235/5427 , C04B2235/604 , C04B2235/6581 , C04B2235/77 , C04B2235/94 , C04B2235/9623 , Y10T428/30
摘要： A carbonaceous support member for a high-temperature heat-treated metal molding object, particularly a setter for heat-treatment in powder metallurgy, is formed as a carbon-ceramic composite shaped product having a bulk density of 1.2-1.6 g/ml and including a carbonaceous matrix and 3-20 wt. % of ceramic particles which are uniformly dispersed in the carbonaceous matrix and partly exposed to the surface of the composite. The support member can effectively prevent carburization of a metal molding object supported thereby during the heat-treatment without causing a problem of peeling of coating layer as encountered in a ceramic-coated support member. The support member may be prepared by compression molding of a powdery mixture of a fine carbon precursor and ceramic particles, followed by heating at 1000-2000° C. to carbonize the fine carbon precursor.
摘要翻译：形成用于高温热处理的金属成型体的碳质支撑构件，特别是粉末冶金用热处理装置，其为堆积密度为1.2〜1.6g / ml的碳陶瓷复合成形体，碳质基质和3-20重量％％的陶瓷颗粒均匀地分散在碳质基质中并且部分地暴露于复合材料的表面。支撑构件可以有效地防止在热处理期间由其支撑的金属模制物体的渗碳，而不会引起如陶瓷涂覆的支撑构件中遇到的涂层剥落的问题。支撑构件可以通过压缩成型细碳前体和陶瓷颗粒的粉末混合物，然后在1000-2000℃加热以使细碳前体碳化来制备。

70. 发明申请

US20110065668A1 PHENYLPYRAZOLE DERIVATIVES 有权
标题翻译：苯并噻唑衍生物
公开(公告)号：US20110065668A1
公开(公告)日：2011-03-17
申请号：US12951978
申请日：2010-11-22
申请人： Toshio NAKAMURA , Makoto Tatsuzuki , Dai Nozawa , Tomoko Tamita , Seiji Masuda , Hiroshi Ohta , Shuhei Kashiwa , Aya Fujino , Shigeyuki Chaki , Toshiharu Shimazaki
发明人： Toshio NAKAMURA , Makoto Tatsuzuki , Dai Nozawa , Tomoko Tamita , Seiji Masuda , Hiroshi Ohta , Shuhei Kashiwa , Aya Fujino , Shigeyuki Chaki , Toshiharu Shimazaki
IPC分类号： A61K31/695 , A61K31/415 , A61K31/5377 , A61K31/553 , A61P25/28 , A61P25/18 , A61P3/10 , A61P25/24 , A61P25/08 , A61P25/00
CPC分类号： C07D231/14 , C07D231/40 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D403/14 , C07D413/04 , C07D413/14
摘要： The present invention provides a prophylactic or therapeutic agent for dementia, Alzheimer's disease, attention-deficit hyperactivity disorder, schizophrenia, eating disorders, obesity, diabetes, hyperlipidemia, sleep disorders, narcolepsy, sleep apnea syndrome, circadian rhythm disorder, depression, allergic rhinitis or other diseases.A phenylpyrazole derivative represented by formula (1) or a pharmaceutically acceptable salt thereof: {wherein R1 and R2, which may be the same or different, each represent C1-C6 alkyl or C3-C8 cycloalkyl, or R1 and R2 are attached to each other together with their adjacent nitrogen atom to form a 4- to 7-membered saturated heterocyclic ring (wherein said saturated heterocyclic ring may be substituted with halogen or C1-C6 alkyl), n represents an integer of 0 to 2, T represents a hydrogen atom, halogen or C1-C6 alkyl, and R represents formula (I): or the like}.
摘要翻译：本发明提供了用于痴呆，阿尔茨海默病，注意缺陷多动障碍，精神分裂症，进食障碍，肥胖症，糖尿病，高脂血症，睡眠障碍，发作性睡眠障碍，睡眠呼吸暂停综合征，昼夜节律紊乱，抑郁，过敏性鼻炎或其他疾病由式（1）表示的苯基吡唑衍生物或其药学上可接受的盐：其中可以相同或不同的R 1和R 2各自表示C 1 -C 6烷基或C 3 -C 8环烷基，或者R 1和R 2各自连接与其相邻的氮原子一起形成4-至7-元饱和杂环（其中所述饱和杂环可被卤素或C 1 -C 6烷基取代），n表示0至2的整数，T表示氢原子，卤素或C 1 -C 6烷基，R表示式（I）：等）。

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