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61. 发明申请

US20060058872A1 Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements 有权
标题翻译：包括组织抓取元件的血管内心脏瓣膜置换的方法和装置
公开(公告)号：US20060058872A1
公开(公告)日：2006-03-16
申请号：US11232444
申请日：2005-09-20
申请人： Amr Salahieh , Daniel Hildebrand , Tom Saul
发明人： Amr Salahieh , Daniel Hildebrand , Tom Saul
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/24 , A61F2/2418 , A61F2/2427 , A61F2/2433 , A61F2/2439 , A61F2/848 , A61F2/88 , A61F2/90 , A61F2210/0014 , A61F2220/0016 , A61F2220/0033 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2250/0069
摘要： The present invention provides an apparatus for endovascularly replacing a patient's heart valve. In some embodiments, the apparatus includes an expandable anchor supporting a replacement valve, the anchor and replacement valve being adapted for percutaneous delivery and deployment to replace the patient's heart valve, the anchor having a braid having atraumatic grasping elements adapted to grasp tissue in a vicinity of the patient's heart valve.
摘要翻译：本发明提供一种用于血管内替换患者心脏瓣膜的装置。在一些实施例中，该装置包括支撑更换瓣膜的可膨胀锚固件，所述锚固器和置换阀适于经皮输送和展开以替换患者的心脏瓣膜，所述锚固器具有编织物，所述编织物具有适于在附近抓住组织的无创伤的抓握元件的病人心脏瓣膜。

62. 发明授权

US09393094B2 Two-part package for medical implant 有权
标题翻译：医疗植入物两部分包装
公开(公告)号：US09393094B2
公开(公告)日：2016-07-19
申请号：US13367733
申请日：2012-02-07
申请人： Amr Salahieh , Tom Saul , Robert Geshlider , Andrea Johnson , Dwight Morejohn , Daniel Hildebrand , Jean-Pierre Dueri
发明人： Amr Salahieh , Tom Saul , Robert Geshlider , Andrea Johnson , Dwight Morejohn , Daniel Hildebrand , Jean-Pierre Dueri
IPC分类号： B65D73/00 , A61F2/00 , A61F2/24 , A61F2/95
CPC分类号： B65D25/04 , A61F2/0095 , A61F2/2427 , A61F2002/9517 , B65B5/04 , B65B55/16 , B65D41/04 , B65D81/22
摘要： The invention provides a two-part package and method of use for a pre-attached medical implant and delivery tool system. The package includes a wet compartment and a dry compartment and allows a pre-attached implant and delivery tool system to be at least partially stored immersed in a fluid in the wet compartment and at least partially stored in the dry compartment. In one embodiment the implant comprises a replacement heart valve, and the heart valve is stored inside the wet compartment while the heart valve delivery tool remains dry in the dry compartment.
摘要翻译：本发明提供了用于预附接的医疗植入物和递送工具系统的两部分包装和使用方法。该包装包括湿室和干燥室，并且允许将预先附着的植入物和递送工具系统至少部分地储存在浸入湿室中的流体中并且至少部分储存在干燥室中。在一个实施例中，植入物包括置换心脏瓣膜，并且心脏瓣膜储存在湿室内，而心脏瓣膜递送工具在干燥室中保持干燥。

63. 发明授权

US08828078B2 Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements 有权
标题翻译：包括组织抓取元件的血管内心脏瓣膜置换的方法和装置
公开(公告)号：US08828078B2
公开(公告)日：2014-09-09
申请号：US11232441
申请日：2005-09-20
申请人： Amr Salahieh , Daniel Hildebrand , Tom Saul
发明人： Amr Salahieh , Daniel Hildebrand , Tom Saul
IPC分类号： A61F2/24 , A61F2/90 , A61F2/848
CPC分类号： A61F2/2412 , A61F2/24 , A61F2/2418 , A61F2/2427 , A61F2/2433 , A61F2/2439 , A61F2/848 , A61F2/88 , A61F2/90 , A61F2210/0014 , A61F2220/0016 , A61F2220/0033 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2250/0069
摘要： A method for endovascularly replacing a patient's heart valve including the following steps: endovascularly delivering an anchor and a replacement valve supported within the anchor to a vicinity of the heart valve in a collapsed delivery configuration, the anchor having grasping elements adapted to grasp tissue in a vicinity of the heart valve; expanding the anchor, thereby rotating the grasping elements; and grasping the tissue with the rotating grasping elements.
摘要翻译：一种用于血管内替换患者心脏瓣膜的方法，包括以下步骤：在塌陷递送构造中血管内递送锚固件和支撑在锚固件内的置换瓣膜至心脏瓣膜附近，所述锚固件具有适于在心脏瓣膜附近; 使锚固件膨胀，从而旋转抓持元件; 并用旋转的把持元件抓住组织。

64. 发明授权

US08708953B2 Steerable medical delivery devices and methods of use 有权
标题翻译：可导向的医疗输送装置和使用方法
公开(公告)号：US08708953B2
公开(公告)日：2014-04-29
申请号：US14070232
申请日：2013-11-01
申请人： Amr Salahieh , Jonah Lepak , Emma Leung , Tom Saul , Jean-Pierre Dueri , Brice Arnault De La Menardiere , Clayton Baldwin
发明人： Amr Salahieh , Jonah Lepak , Emma Leung , Tom Saul , Jean-Pierre Dueri , Brice Arnault De La Menardiere , Clayton Baldwin
IPC分类号： A61M31/00
CPC分类号： A61M25/0144 , A61B1/00135 , A61B17/00234 , A61B90/10 , A61B2017/00309 , A61B2017/00314 , A61M25/0013 , A61M25/0045 , A61M25/0053 , A61M25/0136 , A61M25/0138 , A61M25/0147 , A61M2025/0161
摘要： Steerable medical delivery devices and their methods of use.
摘要翻译：可导向的医疗输送装置及其使用方法。

65. 发明申请

US20120132547A1 TWO-PART PACKAGE FOR MEDICAL IMPLANT 有权
标题翻译：医疗植物的两部分包装
公开(公告)号：US20120132547A1
公开(公告)日：2012-05-31
申请号：US13367733
申请日：2012-02-07
申请人： Amr Salahieh , Tom Saul , Robert Geshlider , Andrea Johnson , Dwight Morejohn , Daniel Hildebrand , Jean-Pierre Dueri
发明人： Amr Salahieh , Tom Saul , Robert Geshlider , Andrea Johnson , Dwight Morejohn , Daniel Hildebrand , Jean-Pierre Dueri
IPC分类号： A61J1/00 , B65D81/32
CPC分类号： B65D25/04 , A61F2/0095 , A61F2/2427 , A61F2002/9517 , B65B5/04 , B65B55/16 , B65D41/04 , B65D81/22
摘要： The invention provides a two-part package and method of use for a pre-attached medical implant and delivery tool system. The package includes a wet compartment and a dry compartment and allows a pre-attached implant and delivery tool system to be at least partially stored immersed in a fluid in the wet compartment and at least partially stored in the dry compartment. In one embodiment the implant comprises a replacement heart valve, and the heart valve is stored inside the wet compartment while the heart valve delivery tool remains dry in the dry compartment.
摘要翻译：本发明提供了用于预附接的医疗植入物和递送工具系统的两部分包装和使用方法。该包装包括湿室和干燥室，并且允许将预先附着的植入物和递送工具系统至少部分地储存在浸入湿室中的流体中并且至少部分储存在干燥室中。在一个实施例中，植入物包括置换心脏瓣膜，并且心脏瓣膜储存在湿室内，而心脏瓣膜递送工具在干燥室中保持干燥。

66. 发明申请

US20060173524A1 Medical Implant Delivery And Deployment Tool 有权
标题翻译：医疗植入物交付和部署工具
公开(公告)号：US20060173524A1
公开(公告)日：2006-08-03
申请号：US11275912
申请日：2006-02-02
申请人： Amr Salahieh , Dwight Morejohn , Ulrich Haug , Brian Brandt , Hans Valencia , Tom Saul
发明人： Amr Salahieh , Dwight Morejohn , Ulrich Haug , Brian Brandt , Hans Valencia , Tom Saul
IPC分类号： A61F2/06
CPC分类号： A61F2/2439 , A61B17/068 , A61B2017/00243 , A61F2/2418 , A61F2/90 , A61F2002/9517
摘要： An apparatus for endovascularly replacing a patient's heart valve. In some embodiments, the apparatus includes a replacement heart valve implant comprising a valve and an expandable anchor; and a deployment tool adapted to endovascularly deliver the replacement heart valve implant to an implant site within the patient, the deployment tool comprising an actuator adapted to exert an axially directed force on the anchor. The invention also provides a method for endovascularly replacing a heart valve of a patient. In some embodiments, the method includes the steps of endovascularly delivering a replacement heart valve implant having a valve and an anchor to an implant site within the patient; and applying an axially directed force from an actuator outside of the patient to the anchor. In invention also provides deployment tools for performing the method.
摘要翻译：用于血管内置换患者心脏瓣膜的装置。在一些实施例中，该装置包括置换心脏瓣膜植入体，其包括阀和可扩张锚; 以及适于将替代心脏瓣膜植入物血管内输送到患者体内的植入部位的部署工具，所述展开工具包括适于在锚固件上施加轴向力的致动器。本发明还提供一种用于血管内替换患者心脏瓣膜的方法。在一些实施例中，该方法包括以下步骤：血管内递送具有瓣膜和锚的置换心脏瓣膜植入物到患者体内的植入部位; 以及将来自所述患者外部的致动器的轴向力施加到所述锚固件。本发明还提供了用于执行该方法的部署工具。

67. 发明申请

US20050137697A1 Leaflet engagement elements and methods for use thereof 有权
公开(公告)号：US20050137697A1
公开(公告)日：2005-06-23
申请号：US10971535
申请日：2004-10-21
申请人： Amr Salahieh , Brian Brandt , Robert Geshlider , Dwight Morejohn , Tom Saul
发明人： Amr Salahieh , Brian Brandt , Robert Geshlider , Dwight Morejohn , Tom Saul
IPC分类号： A61F2/06 , A61F2/24 , A61F2/90
CPC分类号： A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9528 , A61F2230/0054 , A61F2230/0078 , A61F2250/006
摘要： The present invention relates to apparatus for methods for endovascularly replacing a patient's heart valve. The apparatus includes an expandable anchor with leaflet engagement elements on the proximal end of the anchor and a replacement valve. The leaflet engagement elements can be used to prevent distal migration and insure proper positioning of the apparatus.

68. 发明申请

US20170203077A1 STEERABLE MEDICAL DEVICES, SYSTEMS, AND METHODS OF USE 审中-公开
公开(公告)号：US20170203077A1
公开(公告)日：2017-07-20
申请号：US15375027
申请日：2016-12-09
申请人： Amr Salahieh , Jonah Lepak , Emma Lepak , Tom Saul , Jean-Pierre Dueri , Joseph Creagan Trautman , Christopher T. Cheng , Richard Joseph Renati , Colin Mixter , Marc Bitoun
发明人： Amr Salahieh , Jonah Lepak , Emma Lepak , Tom Saul , Jean-Pierre Dueri , Joseph Creagan Trautman , Christopher T. Cheng , Richard Joseph Renati , Colin Mixter , Marc Bitoun
IPC分类号： A61M25/01 , A61M25/00
CPC分类号： A61M25/0147 , A61B1/00147 , A61B1/0052 , A61B1/0055 , A61M25/0012 , A61M25/005 , A61M25/0053 , A61M25/0136 , A61M25/0138 , A61M25/0141 , A61M2025/0004
摘要： Steerable medical devices and methods of use. In some embodiments, the steerable medical devices can be steered bi-directionally. In some embodiments the steerable medical devices include a first flexible tubular member and a second flexible tubular member secured together at a location distal to a steerable portion of the steerable medical device.

69. 发明授权

US08323241B2 Steerable medical delivery devices and methods of use 有权
标题翻译：可导向的医疗输送装置和使用方法
公开(公告)号：US08323241B2
公开(公告)日：2012-12-04
申请号：US12823049
申请日：2010-06-24
申请人： Amr Salahieh , Jonah Lepak , Emma Leung , Tom Saul , Jean-Pierre Dueri
发明人： Amr Salahieh , Jonah Lepak , Emma Leung , Tom Saul , Jean-Pierre Dueri
IPC分类号： A61M31/00
CPC分类号： A61M25/0136 , A61M25/0138 , A61M25/0147 , A61M25/0152 , A61M2025/0161
摘要： Steerable medical delivery devices and their methods of use.
摘要翻译：可导向的医疗输送装置及其使用方法。

70. 发明授权

US08052749B2 Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements 有权
标题翻译：包括组织抓取元件的血管内心脏瓣膜置换的方法和装置
公开(公告)号：US08052749B2
公开(公告)日：2011-11-08
申请号：US11232444
申请日：2005-09-20
申请人： Amr Salahieh , Daniel Hildebrand , Tom Saul
发明人： Amr Salahieh , Daniel Hildebrand , Tom Saul
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/24 , A61F2/2418 , A61F2/2427 , A61F2/2433 , A61F2/2439 , A61F2/848 , A61F2/88 , A61F2/90 , A61F2210/0014 , A61F2220/0016 , A61F2220/0033 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2250/0069
摘要： The present invention provides an apparatus for endovascularly replacing a patient's heart valve. In some embodiments, the apparatus includes an expandable anchor supporting a replacement valve, the anchor and replacement valve being adapted for percutaneous delivery and deployment to replace the patient's heart valve, the anchor having a braid having atraumatic grasping elements adapted to grasp tissue in a vicinity of the patient's heart valve.
摘要翻译：本发明提供一种用于血管内替换患者心脏瓣膜的装置。在一些实施例中，该装置包括支撑更换瓣膜的可膨胀锚固件，所述锚固器和置换阀适于经皮输送和展开以替换患者的心脏瓣膜，所述锚固器具有编织物，所述编织物具有适于在附近抓住组织的无创伤的抓握元件的病人心脏瓣膜。

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