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61. 发明申请

US20060148998A1 Solid reagents 失效
标题翻译：固体试剂
公开(公告)号：US20060148998A1
公开(公告)日：2006-07-06
申请号：US11366467
申请日：2006-03-03
申请人： Makoto Komatsu , Kazuyoshi Takeda
发明人： Makoto Komatsu , Kazuyoshi Takeda
IPC分类号： C08F32/00
CPC分类号： D06M14/18 , C08F255/00 , C08F255/02 , C08F255/023 , C08F255/026 , C08F257/02 , C08F259/00 , C08F291/00 , D06M14/26 , D06M14/28
摘要： An object of the present invention is to provide a novel solid reagent capable of solving the problems of conventional solid reagents based on resin beads. The present invention relates to a solid reagent comprising an organic polymer base in which a polymer side chain is introduced onto the backbone of the organic polymer base via graft polymerization and a reactive functional group is introduced onto the polymer side chain. The organic polymer base is preferably in the form of a fiber, a woven or nonwoven fabric consisting of an assembly of fibers, a porous membrane or a hollow fiber membrane. The graft polymerization is preferably a radiation-induced graft polymerization. Solid reagents according to the present invention can be used in various organic synthetic reactions.
摘要翻译：本发明的目的是提供一种能够解决基于树脂珠的常规固体试剂问题的新型固体试剂。本发明涉及包含有机聚合物基质的固体试剂，其中通过接枝聚合将聚合物侧链引入有机聚合物基体的主链上，并将反应性官能团引入到聚合物侧链上。有机聚合物基质优选为由纤维，多孔膜或中空纤维膜组成的纤维，织造或非织造织物的形式。接枝聚合优选是辐射诱导的接枝聚合。根据本发明的固体试剂可用于各种有机合成反应。

62. 发明授权

US06844371B1 Material having separating function 有权
标题翻译：具有分离功能的材料
公开(公告)号：US06844371B1
公开(公告)日：2005-01-18
申请号：US10111080
申请日：2000-10-20
申请人： Makoto Komatsu , Kazuyoshi Takeda , Kunio Fujiwara , Takeshi Takai
发明人： Makoto Komatsu , Kazuyoshi Takeda , Kunio Fujiwara , Takeshi Takai
IPC分类号： B01D53/02 , B01D39/14 , B01D39/16 , B01J20/26 , B01J39/18 , B01J39/20 , B01J41/12 , B01J45/00 , C08F8/44 , C08J7/18 , D06M14/08 , D06M15/233 , D06M101/00 , D06M101/16 , C08F291/00 , D06M4/10
CPC分类号： B01J45/00 , B01J20/26 , B01J39/18 , B01J39/20 , C08F8/44 , C08F291/00
摘要： An object of the present invention is to provide a separation functional material having more excellent adsorptive separation performance than previously. In order to attain this object, separation functional materials of the present invention are characterized in that they are formed by introducing a polymer side chain derived from a p-haloalkylstyrene onto the backbone of an organic polymer base and introducing a functional group onto the polymer side chain.
摘要翻译：本发明的目的是提供一种具有比以前更好的吸附分离性能的分离功能材料。为了达到这个目的，本发明的分离功能材料的特征在于它们是通过将衍生自对卤代烷基苯乙烯的聚合物侧链引入有机聚合物基体的主链上并将官能团引入聚合物侧而形成的链。

63. 发明授权

US5436374A Process for producing 4-formyl-4'-methylbiphenyl from biphenyl 失效
标题翻译：从联苯生产4-甲酰基-4'-甲基联苯的方法
公开(公告)号：US5436374A
公开(公告)日：1995-07-25
申请号：US281126
申请日：1994-07-28
申请人： Makoto Komatsu , Susumu Fujiyama , Koichi Kida , Mitsuharu Kitamura
发明人： Makoto Komatsu , Susumu Fujiyama , Koichi Kida , Mitsuharu Kitamura
IPC分类号： B01J27/12 , C07B61/00 , C07C45/49 , C07C47/546
CPC分类号： C07C45/49
摘要： A process for producing a 4-formyl-4'-methylbiphenyl from a biphenyl which comprises conducting the carbonylation of the biphenyl with carbon monoxide in the presence of a HF-BF.sub.3 catalyst in a carbonylation reactor to obtain the resulting reaction product solution containing a 4-formylbiphenyl, separating the 4-formylbiphenyl from the reaction product solution, hydrogenating the separated 4-formylbiphenyl to obtain a 4-methylbiphenyl, recycling the 4-methylbiphenyl to the carbonylation reactor, and then conducting both the carbonylation of the biphenyl with carbon monoxide to obtain a formylbiphenyl and the carbonylation of the 4-methylbiphenyl with carbon monoxide to obtain a 4-formyl-4'-methylbiphenyl simultaneously in the presence of the HF-BF.sub.3 catalyst in the carbonylation reactor.
摘要翻译：一种由联苯生产4-甲酰基-4'-甲基联苯的方法，其包括在羰基化反应器中，在HF-BF 3催化剂存在下，用一氧化碳进行联苯的羰基化，得到所得到的含有4 - 甲酰基联苯，从反应产物溶液中分离4-甲酰基联苯，氢化分离的4-甲酰基联苯，得到4-甲基联苯，将4-甲基联苯循环到羰基化反应器中，然后进行联苯与一氧化碳的羰基化反应在羰基化反应器中，在HF-BF 3催化剂的存在下，用一氧化碳得到甲酰基联苯和4-甲基联苯羰基化，得到4-甲酰基-4'-甲基联苯。

64. 发明授权

US4694017A 2-amido 3(oxindol-3-yl)propionic acids having antiulcer activity 失效
标题翻译：具有抗溃疡活性的2-酰氨基3（羟吲哚-3-基）丙酸
公开(公告)号：US4694017A
公开(公告)日：1987-09-15
申请号：US610574
申请日：1984-05-15
申请人： Minoru Uchida , Makoto Komatsu , Kazuyuki Nakagawa
发明人： Minoru Uchida , Makoto Komatsu , Kazuyuki Nakagawa
IPC分类号： C07D209/20 , C07D209/34 , A61K31/405
CPC分类号： C07D209/34 , C07D209/20
摘要： Novel oxindole derivative and salt thereof represented by the general formula, ##STR1## wherein R.sup.1 is a hydrogen atom, a lower alkyl group, a lower alkenyl group, a lower alkynyl group or a phenyl-lower alkyl group; R.sup.2 is a hydrogen atom or a lower alkyl group; R.sup.3 is a hydrogen atom, a cycloalkylcarbonyl group, a benzoyl group which may have 1 to 3 substituents selected from the group consisting of a halogen atom, a lower alkyl group and a lower alkoxy group on the phenyl ring, or a phenyl-lower alkanoyl group which may have halogen atoms as the substituents on the phenyl ring; provided that when R.sup.4 is a hydrogen atom, then R.sup.3 should be neither a hydrogen atom nor a lower alkyl group.The novel oxindole derivative and salt thereof possesses anti-peptic ulcer effects and are useful as anti-peptic ulcer agents.
摘要翻译：其中R1为氢原子，低级烷基，低级烯基，低级炔基或苯基 - 低级烷基的通式为的新型羟基吲哚衍生物及其盐。 R2是氢原子或低级烷基; R3是氢原子，环烷基羰基，可以具有1〜3个选自苯基环上的卤素原子，低级烷基和低级烷氧基的取代基的苯甲酰基，或苯基 - 低级烷酰基可以具有卤素原子作为苯环上的取代基的基团; 条件是当R 4为氢原子时，R 3既不是氢原子也不是低级烷基。新羟吲哚衍生物及其盐具有抗消化性溃疡作用，可用作抗消化性溃疡药。

65. 发明授权

US4281179A Process for producing terephthalic acid with high purity 失效
标题翻译：高纯度对苯二甲酸生产方法
公开(公告)号：US4281179A
公开(公告)日：1981-07-28
申请号：US119969
申请日：1980-02-08
申请人： Makoto Komatsu , Toru Tanaka
发明人： Makoto Komatsu , Toru Tanaka
IPC分类号： C07C63/26 , B01J27/00 , C07C51/00 , C07C51/255 , C07C67/00 , C07C51/16
CPC分类号： C07C51/255 , Y02P20/52
摘要： Terephthalic acid with a high purity and high whiteness is produced by oxidizing p-tolualdehyde with molecular oxygen such as air in the presence of a heavy metal catalyst of manganese and/or cerium, a bromine compound, and a mineral acid in water as a solvent at a bromine compound concentration of 0.5-12% by weight on the basis of the reaction solution in terms of bromine ions and at a ratio of g-equivalents of hydrogen ions of the mineral acid to sum total of g-equivalents of the hydrogen ions and manganese and/or cerium ions of 1-85% and at a ratio of sum total of g-equivalents of the hydrogen ions and manganese and/or cerium ions to g-equivalents of bromine ions of 0.5-5. Terephthalic acid thus produced is directly polymerizable with glycols without any purification.
摘要翻译：具有高纯度和高白度的对苯二甲酸通过在分子氧如空气中在锰和/或铈，溴化合物和无机酸在水中作为溶剂的重金属催化剂存在下氧化对甲苯甲酸而产生溴化合物浓度为0.5-12重量％，以溴离子为基础的反应溶液和无机酸的氢离子的g-当量比与氢离子的g-当量的总和的总和以及1-85％的锰和/或铈离子，以氢离子和锰和/或铈离子的g当量与γ-离子的g-当量的总和为0.5-5的比率。如此制备的对苯二甲酸可直接与二醇进行聚合，无需任何纯化。

66. 发明授权

US4268690A Process for producing terephthalic acid of high purity 失效
标题翻译：制备高纯度对苯二甲酸的方法
公开(公告)号：US4268690A
公开(公告)日：1981-05-19
申请号：US55198
申请日：1979-07-02
申请人： Makoto Komatsu , Tazuo Ohta , Toru Tanaka , Ryoichi Oda , Yuji Takamizawa
发明人： Makoto Komatsu , Tazuo Ohta , Toru Tanaka , Ryoichi Oda , Yuji Takamizawa
IPC分类号： C07C51/47 , B01D9/02 , C07C51/00 , C07C51/255 , C07C51/43 , C07C63/26 , C07C67/00 , C07C51/16 , C07C51/42
CPC分类号： C07C51/255 , C07C51/43 , Y02P20/52
摘要： Terephthalic acid of high purity is continuously produced in a high yield by oxidizing p-tolualdehyde with a molecular oxygen-containing gas in the presence of bromine ions as a catalyst in a water solvent, contacting the resulting slurry solution containing crude terephthalic acid with an ascending stream of high temperature water of 180.degree.-320.degree. C., and withdrawing the water solvent together with the ascending stream of high temperature of water upwardly, while settling down crystalline terephthalic acid through the ascending stream of high temperature water and withdrawing the crystalline terephthalic acid together with a portion of the high temperature water downwardly.
摘要翻译：在水溶剂中，在溴离子作为催化剂存在下，用含分子氧的气体氧化对甲苯甲醛，从而以高收率连续生产高纯度的对苯二甲酸，使含有粗对苯二甲酸的浆液与上升 180℃-320℃的高温水流，并将水溶剂与上升水的上升水一起向上取出，同时通过高温水的上升下降结晶对苯二甲酸，并将结晶对苯二甲酸酸与一部分高温水一起向下。

67. 发明授权

US4214100A Process for preventing blackening of phthalic acid 失效
标题翻译：防止苯二甲酸黑化的方法
公开(公告)号：US4214100A
公开(公告)日：1980-07-22
申请号：US857709
申请日：1977-12-05
申请人： Makoto Komatsu , Tazuo Ohta , Toru Tanaka , Kimiko Akagi
发明人： Makoto Komatsu , Tazuo Ohta , Toru Tanaka , Kimiko Akagi
IPC分类号： C07C63/15 , C07C51/00 , C07C51/265 , C07C63/26 , C07C67/00 , C07C51/33
CPC分类号： C07C51/265
摘要： In the production of phthalic acid by oxidizing, in a liquid phase, tolualdehyde with molecular oxygen or a gas containing the molecular oxygen in the presence of heavy metal salt containing a Mn salt, especially both Mn and Co salts, and a bromine compound, using a lower aliphatic monocarboxylic acid as a reaction solvent, a blackening of phthalic acid is effectively prevented by conducting the oxidation of tolualdehyde in the presence of an alkylbenzene in an amount satisfying the following formula (1);M.ltoreq.-0.15A.sup.2 +15A+40 (1)wherein M is a Mn atom concentration in.ppm by weight on the basis of the reaction solution, and A is an amount in % by weight of the alkylbenzene added on the basis of the total of tolualdehyde and said alkylbenzene, and is in a range of from more than 0 to 50 inclusive.
摘要翻译：在通过在含有Mn盐，特别是Mn和Co盐以及溴化合物的重金属盐存在下，用分子氧或含有分子氧的气体在液相中氧化甲苯甲醛来生产邻苯二甲酸，使用作为反应溶剂的低级脂族一元羧酸，通过在满足下式（1）的量的烷基苯存在下进行甲苯甲醛的氧化有效地防止了邻苯二甲酸的黑化; M = 0.15A2 + 15A + 40（1）其中M是以反应溶液为基准的Mn原子浓度为ppm重量ppm，A为基于添加量的烷基苯的重量％的甲苯甲醛和所述烷基苯的总量，并且在大于0至50的范围内。

68. 发明授权

US09983509B2 Powder container, powder supply device and image forming apparatus 有权
公开(公告)号：US09983509B2
公开(公告)日：2018-05-29
申请号：US15383141
申请日：2016-12-19
申请人： Junichi Matsumoto , Tsukuru Kai , Hiroshi Hosokawa , Makoto Komatsu , Tadashi Hayakawa , Yuzuru Ozawa
发明人： Junichi Matsumoto , Tsukuru Kai , Hiroshi Hosokawa , Makoto Komatsu , Tadashi Hayakawa , Yuzuru Ozawa
IPC分类号： G03G15/08
CPC分类号： G03G15/0886 , G03G15/0832 , G03G15/0865 , G03G15/0872 , G03G15/0879 , G03G2215/0132
摘要： Provided is a powder container having a new structure capable of stable discharge and transport of a powder contained in a container by enabling the powder to be reliably discharged to the outside of the package while preventing the powder from spilling and flying out of the container. The powder container has a container body (138) for transporting powder contained therein from a first end side (138a) to a second end side (138b) thereof by self-rotating; a nozzle receiver (139) having a nozzle receiving hole (insertion section) (139a) arranged inside the second end side of the container body and configured to allow a transport nozzle (162) having a powder receiving inlet (170) to be inserted therein, and a supply port 139b arranged in at least a part of the nozzle receiver (139) and configured to supply the powder in the container body (138) to the powder receiving inlet (170): and a shutter (140) supported by the nozzle receiver 139 and configured to open and close the nozzle receiving hole (insertion section) 139a by sliding in response to insertion of the transport nozzle 162 into the nozzle receiver (139).

69. 发明授权

US09809609B2 Water-soluble benzoazepine compound and its pharmaceutical composition 有权
公开(公告)号：US09809609B2
公开(公告)日：2017-11-07
申请号：US13461642
申请日：2012-05-01
申请人： Makoto Komatsu , Fumitaka Goto , Yasuhiro Menjo , Keigo Yamada , Takakuni Matsuda , Yusuke Kato
发明人： Makoto Komatsu , Fumitaka Goto , Yasuhiro Menjo , Keigo Yamada , Takakuni Matsuda , Yusuke Kato
IPC分类号： C07F9/553 , A61K31/675 , A61P9/08 , A61P9/12 , A61P7/02 , A61P7/00
CPC分类号： C07F9/5535 , Y02P20/55
摘要： The present invention provides a benzoazepine compound represented by following general formula (1): or a salt thereof, wherein R represents a hydrogen atom, a hydroxy group optionally protected with a protecting group, etc., R1 represents a hydrogen atom or hydroxy-protecting group, and X represents an oxygen atom or a sulfur atom. The benzoazepine compound of the present invention and salts thereof have high solubility in water, and can be suitably used for injections.

70. 发明授权

US09482987B2 Powder container, powder supply device and image forming apparatus 有权
标题翻译：粉末容器，粉末供给装置和成像装置
公开(公告)号：US09482987B2
公开(公告)日：2016-11-01
申请号：US13991250
申请日：2011-12-02
申请人： Junichi Matsumoto , Tsukuru Kai , Hiroshi Hosokawa , Makoto Komatsu , Tadashi Hayakawa , Yuzuru Ozawa
发明人： Junichi Matsumoto , Tsukuru Kai , Hiroshi Hosokawa , Makoto Komatsu , Tadashi Hayakawa , Yuzuru Ozawa
IPC分类号： G03G15/08
CPC分类号： G03G15/0886 , G03G15/0832 , G03G15/0865 , G03G15/0872 , G03G15/0879 , G03G2215/0132
摘要： Provided is a powder container having a new structure capable of stable discharge and transport of a powder contained in a container by enabling the powder to be reliably discharged to the outside of the package while preventing the powder from spilling and flying out of the container. The powder container has a container body (138) for transporting powder contained therein from a first end side (138a) to a second end side (138b) thereof by self-rotating; a nozzle receiver (139) having a nozzle receiving hole (insertion section) (139a) arranged inside the second end side of the container body and configured to allow a transport nozzle (162) having a powder receiving inlet (170) to be inserted therein, and a supply port 139b arranged in at least a part of the nozzle receiver (139) and configured to supply the powder in the container body (138) to the powder receiving inlet (170): and a shutter (140) supported by the nozzle receiver 139 and configured to open and close the nozzle receiving hole (insertion section) 139a by sliding in response to insertion of the transport nozzle 162 into the nozzle receiver (139).
摘要翻译：本发明提供一种粉末容器，其具有通过使粉末能够可靠地排出到包装外部而能够稳定地排出和运送容器中的粉末的结构，同时防止粉末溢出并从容器中飞出。该粉末容器具有：容纳体，用于通过自转旋转从第一端侧（138a）向第二端侧（138b）输送其中所含的粉末; 喷嘴接收器（139），其具有布置在容器主体的第二端侧内侧的喷嘴接收孔（插入部）（139a），并且构造成允许具有粉末接收入口（170）的输送喷嘴（162）插入其中以及布置在喷嘴接收器（139）的至少一部分中并被配置为将粉末容纳在容器主体（138）中的粉末供应到粉末接收入口（170）的供应口139b，以及由所述容器主体喷嘴接收器139，并且构造成响应于将输送喷嘴162插入喷嘴接收器（139）而滑动来打开和关闭喷嘴接收孔（插入部）139a。

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