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61. 发明申请

US20090271762A1 BUSINESS SOFTWARE APPLICATION SYSTEM AND METHOD 审中-公开
标题翻译：业务软件应用系统和方法
公开(公告)号：US20090271762A1
公开(公告)日：2009-10-29
申请号：US12432086
申请日：2009-04-29
申请人： Jacob Taylor , Lila Alexei Tretikov , Majed Itani , Joseph Parsons , Travis Swicegood , Matt Heitzenroder , Andrew Wu , Roger Smith , John Mertic
发明人： Jacob Taylor , Lila Alexei Tretikov , Majed Itani , Joseph Parsons , Travis Swicegood , Matt Heitzenroder , Andrew Wu , Roger Smith , John Mertic
IPC分类号： G06F9/44 , G06F3/00
CPC分类号： G06F21/6227 , G06F2221/2101 , G06Q10/10
摘要： A business software application system and method are provided.
摘要翻译：提供商业软件应用系统和方法。

62. 发明授权

US07528255B2 Hydroxy, ω-carboxyaryl substituted diphenyl ureas and dirivatives thereof as raf kinase inhibitors 有权
标题翻译：羟基，ω-羧基芳基取代的二苯基脲和其衍生物作为raf激酶抑制剂
公开(公告)号：US07528255B2
公开(公告)日：2009-05-05
申请号：US10071248
申请日：2002-02-11
申请人： Bernd Riedl , Jacques Dumas , Uday Khire , Timothy Lowinger , William Scott , Roger Smith , Jill Wood
发明人： Bernd Riedl , Jacques Dumas , Uday Khire , Timothy Lowinger , William Scott , Roger Smith , Jill Wood
IPC分类号： C07D211/72 , C07D213/62 , C07D213/78
CPC分类号： C07D295/192 , A61K31/17 , A61K31/18 , A61K31/24 , A61K31/341 , A61K31/40 , A61K31/4035 , A61K31/44 , A61K31/4439 , A61K31/4453 , A61K31/495 , A61K31/496 , A61K31/5375 , A61K31/5377 , C07C275/28 , C07C275/30 , C07C275/32 , C07C275/36 , C07C275/40 , C07C311/29 , C07C317/22 , C07D209/46 , C07D209/48 , C07D209/50 , C07D213/75 , C07D213/80 , C07D213/81 , C07D295/073 , C07D295/12 , C07D295/13 , C07D295/135 , C07D295/18 , C07D401/12 , C07F7/1804
摘要： The invention relates to the use of a group of aryl ureas in treating raf mediated diseases and pharmaceutical compositions for use in such therapy of the formula wherein, Y is NHR Hal is chlorine or bromine, R is H, CH3 or CH2OH, and X1 to X7 are each, independently, H, OH or —OC(O)C1-C4 alkyl, or a salt purified stereoisomer thereof, wherein at least one of X1 to X7 is OH or —OC(O)C1-C4 alkyl.
摘要翻译：本发明涉及一组芳基脲在治疗raf介导的疾病中的用途以及用于下列治疗的药物组合物：其中Y是NHR Hal是氯或溴，R是H，CH3或CH2OH，X1至 X 7各自独立地为H，OH或-OC（O）C 1 -C 4烷基或其盐纯化的立体异构体，其中X 1至X 7中的至少一个为OH或-OC（O）C 1 -C 4烷基。

63. 发明申请

US20080032979A1 Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinease Inhibitors 审中-公开
标题翻译： ω-羧酰基取代的二苯基脲作为Raf Kinease抑制剂
公开(公告)号：US20080032979A1
公开(公告)日：2008-02-07
申请号：US11845595
申请日：2007-08-27
申请人： Bernd Riedl , Jacques Dumas , Uday Khire , Timothy Lowinger , Scott William , Roger Smith , Jill Wood , Mary-Katherine Monahan , Reink Natero , Joel Renick , Robert Sibley
发明人： Bernd Riedl , Jacques Dumas , Uday Khire , Timothy Lowinger , Scott William , Roger Smith , Jill Wood , Mary-Katherine Monahan , Reink Natero , Joel Renick , Robert Sibley
IPC分类号： A61K31/4035 , A61K31/17 , A61K31/44 , A61K31/5377 , A61P35/00 , C07C275/28 , C07D209/48 , C07D213/62 , C07D413/12
CPC分类号： C07C275/36 , A61K31/17 , A61K31/18 , A61K31/24 , A61K31/341 , A61K31/40 , A61K31/4035 , A61K31/44 , A61K31/4439 , A61K31/4453 , A61K31/495 , A61K31/496 , A61K31/5375 , A61K31/5377 , C07C275/28 , C07C275/30 , C07C275/32 , C07C275/40 , C07C311/29 , C07C317/22 , C07D209/46 , C07D209/48 , C07D209/50 , C07D213/75 , C07D213/80 , C07D213/81 , C07D213/82 , C07D295/073 , C07D295/12 , C07D295/13 , C07D295/135 , C07D295/18 , C07D295/192 , C07D401/12 , C07D413/12 , C07F7/1804
摘要： This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy.
摘要翻译：本发明涉及一组芳基脲在治疗raf介导的疾病中的用途，以及用于此类治疗的药物组合物。

64. 发明申请

US20080028021A1 Customer relationship management system and method 审中-公开
公开(公告)号：US20080028021A1
公开(公告)日：2008-01-31
申请号：US11717503
申请日：2007-03-12
申请人： John Roberts , Jacob Taylor , Clinton Oram , Andrew Dreisch , Majed Itani , Wayne Pan , Roger Smith , Julian Ostrow , Chris Nojima
发明人： John Roberts , Jacob Taylor , Clinton Oram , Andrew Dreisch , Majed Itani , Wayne Pan , Roger Smith , Julian Ostrow , Chris Nojima
IPC分类号： G06F15/16
CPC分类号： G06Q30/06
摘要： A software-based customer relationship management system and method.

65. 发明申请

US20050256174A1 Raf kinase inhibitors 审中-公开
标题翻译： Raf激酶抑制剂
公开(公告)号：US20050256174A1
公开(公告)日：2005-11-17
申请号：US11149332
申请日：2005-06-10
申请人： Jill Wood , Hanno Wild , Daniel Rogers , John Lyons , Michael Katz , Yolanda Caringal , Robert Dally , Wendy Lee , Roger Smith , Cheri Blum
发明人： Jill Wood , Hanno Wild , Daniel Rogers , John Lyons , Michael Katz , Yolanda Caringal , Robert Dally , Wendy Lee , Roger Smith , Cheri Blum
IPC分类号： A61K31/38 , A61K31/381 , A61K31/416 , A61K31/433 , C07D207/34 , C07D307/68 , C07D333/38 , C07D333/42 , C07D409/00 , C07D409/12 , C07D417/12
CPC分类号： C07D207/34 , C07D307/68 , C07D333/38 , C07D409/12 , C07D417/12 , C07D471/04
摘要： Methods of treating tumors mediated by raf kinase, with substituted urea compounds, and such compounds per se.
摘要翻译：治疗由raf激酶介导的肿瘤与取代的脲化合物及其化合物本身的方法。

66. 发明申请

US20050191451A1 Container having fluorescent indicia 有权
标题翻译：容器有荧光标记
公开(公告)号：US20050191451A1
公开(公告)日：2005-09-01
申请号：US10789875
申请日：2004-02-27
申请人： Louis Osika , Roger Smith
发明人： Louis Osika , Roger Smith
IPC分类号： A61J1/00 , B29C45/00 , B29C45/37 , B29C49/00 , B29C49/06 , B29C49/22 , B65D1/02 , G09F3/00 , G09F7/16 , B65D1/00
CPC分类号： B65D1/0215 , B29B2911/14053 , B29B2911/14066 , B29B2911/1408 , B29B2911/14093 , B29B2911/1412 , B29B2911/14126 , B29B2911/14146 , B29B2911/14153 , B29B2911/14326 , B29B2911/14331 , B29B2911/14333 , B29B2911/14337 , B29B2911/1444 , B29B2911/14466 , B29B2911/1448 , B29C49/0073 , B29C49/06 , B29C49/221 , B29C2795/002 , B29K2067/00 , B29K2105/16 , B29K2995/0018 , B29K2995/003 , B29K2995/0067 , B29L2031/7158 , B65D2203/00 , B65D2203/12 , G09F3/00 , G09F7/16 , Y10T428/1352 , Y10T428/1393
摘要： A method of making an identifiable article such as a container or container preform. A molded plastic container or container preform is provided that includes a wall having at least one layer of matrix resin and at least one layer of barrier resin that is blended with an additive. The wall has at least one localized portion of predetermined geometry in which the barrier layer is thicker than surrounding portions of the wall, and within which the additive is discernable under visible or UV light so as to provide a means to prevent use of counterfeit containers.
摘要翻译：制造可识别物品如容器或容器预制件的方法。提供了一种模制塑料容器或容器预制件，其包括具有至少一层基质树脂的壁和与添加剂共混的至少一层阻隔树脂。壁具有预定几何形状的至少一个局部部分，其中阻挡层比壁的周围部分更厚，并且其中添加剂在可见光或紫外光下可辨别，以便提供防止使用假冒容器的手段。

67. 发明申请

US20050023948A1 Method and apparatus for maintaining alignment of a cyclotron dee 失效
标题翻译：用于保持回旋加速器对准的方法和装置
公开(公告)号：US20050023948A1
公开(公告)日：2005-02-03
申请号：US10631425
申请日：2003-07-31
申请人： Edward Mastrangeli , Nevin Johns , Roger Smith , Timothy Erickson
发明人： Edward Mastrangeli , Nevin Johns , Roger Smith , Timothy Erickson
IPC分类号： H05H13/00 , H05H1/00
CPC分类号： H05H13/00
摘要： A technique is provided for the alignment of an H/D puller for use in a cyclotron. One aspect of the technique comprises magnetically attaching a pair of feeler gages to an alignment tool for use in aligning the H/D puller. The magnetic retention of the feeler gages allows a field engineer to make the desired adjustments to align the H/D puller. Another aspect of the present technique provides for the H/D puller to include a replaceable tip such that the tip may be replaced without removing the H/D puller. Because the H/D puller is not removed and replaced, the alignment of the H/D puller to the ion source is maintained.
摘要翻译：提供了用于在回旋加速器中使用的H / D拉拔器的对准的技术。该技术的一个方面包括将一对测距计磁力附接到对准工具以用于对准H / D拉拔器。测距仪的磁保持能使现场工程师进行所需的调整，使H / D拉杆对齐。本技术的另一方面提供了H / D拉拔器包括可替换的尖端，使得尖端可以被更换而不移除H / D拉拔器。由于H / D拉拔器未被移除并被更换，所以H / D拉拔器与离子源的对准被维持。

68. 发明授权

US06747977B1 Packet interface and method of packetizing information 失效
标题翻译：数据包接口和打包信息的方法
公开(公告)号：US06747977B1
公开(公告)日：2004-06-08
申请号：US09437063
申请日：1999-11-09
申请人： Roger Smith , Simon Daniel Brueckheimer , Fai Tsang
发明人： Roger Smith , Simon Daniel Brueckheimer , Fai Tsang
IPC分类号： H04L1256
CPC分类号： H04L12/5601 , H04L2012/5652 , H04L2012/5654 , H04L2012/5664 , H04L2012/5667 , H04L2012/5671
摘要： To obviate inefficient use of bandwidth in a packetised system, such as a broadband ATM domain, the use or amount of header information sent in relation to a channel is restricted by one of two principal mechanisms, as exemplified in FIGS. 3 and 4. First, control information incident to a packet interface (20) is interrogated by a processor (21) to determine (50) packet length requirements. A packet length indicator is then generated (52) for inclusion within a header (44) of a packet. Alternatively, a frame (30) is pre-partitioned (60) into several packets (32-42) having different lengths. An addressed subscriber unit (28) is allocated (64) a particular channel, i.e. at least one particular packet within the frame (30), based on data throughput requirements (62), whereby the location of the packet within the frame inherently identifies the length of the packet. Optionally, the data rate used within that packet may also be identified inherently by the location of the packet within the frame (30).
摘要翻译：为了避免诸如宽带ATM域之类的分组化系统中的带宽的低效使用，相对于信道发送的报头信息的使用或数量被两个主要机制之一限制，如图1和2所示。首先，由处理器（21）询问入站到分组接口（20）的控制信息，以确定（50）分组长度要求。然后生成分组长度指示符（52）以包括在分组的报头（44）内。或者，帧（30）被预分区（60）成具有不同长度的数个分组（32-42）。基于数据吞吐量要求（62），寻址订户单元（28）被分配（64）特定信道，即帧（30）内的至少一个特定分组（62），由此分组在帧内的位置固有地标识数据包的长度。可选地，在该分组内使用的数据速率也可以由分组在帧（30）内的位置固有地识别。

69. 外观设计

USD476414S1 Pump cassette 失效
标题翻译：泵盒
公开(公告)号：USD476414S1
公开(公告)日：2003-06-24
申请号：US29166389
申请日：2002-08-27
申请人： Bradford L. Buck , James L. Tiefenthal , Edgar Manosalva , Donna Taylor , William Patton , Steve Nelson , Roger Smith
设计人： Bradford L. Buck , James L. Tiefenthal , Edgar Manosalva , Donna Taylor , William Patton , Steve Nelson , Roger Smith

70. 发明授权

US06344476B1 Inhibition of p38 kinase activity by aryl ureas 失效
公开(公告)号：US06344476B1
公开(公告)日：2002-02-05
申请号：US09083396
申请日：1998-05-22
申请人： Gerald Ranges , William Scott , Michael Bombara , Deborah Rauner , Aniko Redman , Roger Smith , Holger Paulsen , David Gunn , Jinshan Chen , Joel Renick
发明人： Gerald Ranges , William Scott , Michael Bombara , Deborah Rauner , Aniko Redman , Roger Smith , Holger Paulsen , David Gunn , Jinshan Chen , Joel Renick
IPC分类号： A61K3138
CPC分类号： A61K31/4709 , A61K31/341 , A61K31/381 , A61K31/40 , A61K31/4025 , A61K31/433 , Y02A50/411 , Y02A50/414
摘要： This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases other than cancer and proteolytic enzyme mediated diseases other than cancer, and pharmaceutical compositions for use in such therapy.

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