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61. 发明授权

US08273776B2 Biphenyl oxadiazole derivatives as sphingosine-1-phosphate receptors modulators 失效
标题翻译：联苯恶二唑衍生物作为鞘氨醇-1-磷酸受体调节剂
公开(公告)号：US08273776B2
公开(公告)日：2012-09-25
申请号：US13086071
申请日：2011-04-13
申请人： Janet A. Takeuchi , Ken Chow , Ling Li
发明人： Janet A. Takeuchi , Ken Chow , Ling Li
IPC分类号： A61K31/4245 , C07D271/06
CPC分类号： C07D271/06
摘要： The present invention relates to novel biphenyl oxadiazole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
摘要翻译：本发明涉及新的联苯恶二唑衍生物，其制备方法，含有它们的药物组合物及其作为药物作为鞘氨醇-1-磷酸受体调节剂的用途。

62. 发明申请

US20120129814A1 NOVEL PHOSPHONIC ACIDS AS S1P RECEPTOR MODULATORS 有权
标题翻译：新型磷酸钠作为S1P受体调节剂
公开(公告)号：US20120129814A1
公开(公告)日：2012-05-24
申请号：US13297855
申请日：2011-11-16
申请人： Janet A. Takeuchi , Ling Li , Ken Chow , Wha Bin Im
发明人： Janet A. Takeuchi , Ling Li , Ken Chow , Wha Bin Im
IPC分类号： A61K31/675 , A61P27/02 , A61P9/10 , A61P9/12 , A61P27/06 , A61P29/00 , A61P11/00 , A61P35/04 , A61P37/06 , A61P25/00 , A61P17/06 , A61P1/00 , A61P13/12 , A61P17/00 , A61P37/08 , A61P11/06 , A61P17/02 , A61P19/08 , A61P19/10 , A61P19/02 , C07F9/653
CPC分类号： C07F9/65318 , A61K31/662 , A61K31/675
摘要： The present invention relates to novel phosphonic acids derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
摘要翻译：本发明涉及新型膦酸衍生物，其制备方法，含有它们的药物组合物及其作为药物作为鞘氨醇-1-磷酸受体调节剂的用途。

63. 发明申请

US20110297008A1 COOKING EQUIPMENT 审中-公开
标题翻译：烹饪设备
公开(公告)号：US20110297008A1
公开(公告)日：2011-12-08
申请号：US13056414
申请日：2009-07-24
申请人： Ling Li , Ping Yan
发明人： Ling Li , Ping Yan
IPC分类号： A47J27/00
CPC分类号： A47J27/002 , A47J27/14
摘要： The present invention provides a cooking equipment comprising a pot, a body bracket, a rotation mechanism and a turning-over mechanism in which the pot is in shape of a barrel, a hemisphere or the like with an opening at its end, the rotation mechanism is connected to the pot to drive the pot to rotate around a rotation axis of the pot, the turning-over mechanism is connected to the pot to drive the pot to turn around a turning-over axis together with the body bracket, and when the cooking equipment is in its operating state, the angle between the rotation axis of the pot and horizontal plane is in the range of 0° to 90°.
摘要翻译：本发明提供了一种烹饪设备，其包括锅，主体托架，旋转机构和翻转机构，其中锅的形状为筒，半球等，其端部具有开口，旋转机构连接到锅以驱动锅围绕锅的旋转轴线旋转，转向机构连接到锅以驱动锅与主体支架一起转动转向轴，并且当烹饪设备处于其操作状态，锅的旋转轴线和水平面之间的角度在0°至90°的范围内。

64. 发明申请

US20110254468A1 VOLTAGE CONVERTER AND DRIVING METHOD FOR USE IN A BACKLIGHT MODULE 有权
标题翻译：用于背光模块的电压转换器和驱动方法
公开(公告)号：US20110254468A1
公开(公告)日：2011-10-20
申请号：US12831231
申请日：2010-07-06
申请人： Ke-Horng Chen , Chi-Lin Chen , Yao-Yi Yang , Ling Li , Chia-Lin Liu , Chi-Neng Mo
发明人： Ke-Horng Chen , Chi-Lin Chen , Yao-Yi Yang , Ling Li , Chia-Lin Liu , Chi-Neng Mo
IPC分类号： H05B37/02
CPC分类号： H05B33/0818 , H05B33/0815
摘要： A voltage converter for use in a backlight module stores energy of an input voltage using an inductor and outputs a plurality of output voltages accordingly. The charging path of the inductor is controlled according to the first output voltage so that the first output voltage can be stabilized. The discharging paths from the inductor to other output voltages are controlled according to the differences between other output voltages and the first output voltage so that other output voltages can also be stabilized.
摘要翻译：用于背光模块的电压转换器使用电感器存储输入电压的能量并相应地输出多个输出电压。根据第一输出电压来控制电感器的充电路径，使得第一输出电压可以稳定。根据其他输出电压和第一输出电压之间的差异，从电感器到其他输出电压的放电路径进行控制，以便其他输出电压也可以稳定。

65. 发明申请

US20110205222A1 METHOD FOR DRIVING LIQUID CRYSTAL DISPLAY DEVICE 审中-公开
标题翻译：驱动液晶显示装置的方法
公开(公告)号：US20110205222A1
公开(公告)日：2011-08-25
申请号：US12774708
申请日：2010-05-05
申请人： HUAN-TING ZHOU , Shian-jun Chiou , Ling Li , Ying-hui Chen , Wen-chih Tai , Chia-lin Liu , Chi-neng Mo
发明人： HUAN-TING ZHOU , Shian-jun Chiou , Ling Li , Ying-hui Chen , Wen-chih Tai , Chia-lin Liu , Chi-neng Mo
IPC分类号： G09G3/36 , G09G5/00
CPC分类号： G09G3/36 , G09G2310/021 , G09G2310/0243
摘要： A method for driving a liquid crystal display device is disclosed. The liquid crystal display device includes a plurality of scan lines, a plurality of data lines, and a plurality of pixel units. Each one of the pixel units is corresponding to one of the scan lines and one of the data lines. The method includes: turning on at least two of the scan lines at the same time, said at least two scan lines being separated from each other by at least one turned off scan line, and said at least two scan lines respectively coupled to distinct one or multiple of the data lines; and transmitting respective image data to the data lines which are coupled to said at least two scan lines. The present invention can solve problems of bad performance and errors in a display image.
摘要翻译：公开了一种驱动液晶显示装置的方法。液晶显示装置包括多条扫描线，多条数据线和多个像素单元。每个像素单元对应于扫描线之一和数据线之一。该方法包括：同时打开至少两条扫描线，所述至少两条扫描线彼此分开至少一条截止的扫描线，并且所述至少两条扫描线分别耦合到不同的扫描线或多个数据线; 并将相应的图像数据发送到耦合到所述至少两条扫描线的数据线。本发明可以解决显示图像中的不良性能和错误的问题。

66. 发明授权

US07679563B2 Reconfigurable frequency selective surfaces for remote sensing of chemical and biological agents 有权
标题翻译：用于遥感化学和生物制剂的可重构频率选择表面
公开(公告)号：US07679563B2
公开(公告)日：2010-03-16
申请号：US10586117
申请日：2005-01-14
申请人： Douglas H. Werner , Theresa S. Mayer , Jeremy A. Bossard , Robert P. Drupp , Xiaotao Liang , Ling Li
发明人： Douglas H. Werner , Theresa S. Mayer , Jeremy A. Bossard , Robert P. Drupp , Xiaotao Liang , Ling Li
IPC分类号： H01Q1/38 , H01Q15/02
CPC分类号： H01Q15/002 , F41H11/134 , F41H11/136
摘要： An improved frequency selective surface (FSS) comprises a periodically replicated unit cell, the unit cell including a material having a first electrical conductivity in the presence of an external condition, and a second electrical conductivity in the absence of an external condition, or in the presence of a modified external condition. For example, the material may be a chemoresistive material, having an electrical conductivity that changes in the presence of a chemical or biological analyte, i.e. having a first value of electrical conductivity in the presence of the analyte, and a second value of electrical conductivity in the absence of the analyte.
摘要翻译：改进的频率选择表面（FSS）包括周期性复制的单位单元，所述单位单元包括在存在外部条件的情况下具有第一导电性的材料，以及在不存在外部条件的情况下的第二导电性，或者在存在修改的外部条件。例如，材料可以是具有导电性的化学耐药材料，其在化学或生物分析物的存在下发生变化，即在分析物的存在下具有第一电导率值，以及第二导电性值没有分析物。

67. 发明授权

US07648967B2 Mutagenic nucleoside analogs for the treatment of viral disease 有权
标题翻译：诱变核苷类似物用于治疗病毒性疾病
公开(公告)号：US07648967B2
公开(公告)日：2010-01-19
申请号：US11353489
申请日：2006-02-13
申请人： Ling Li , Alexander Gall , Richard Daifuku
发明人： Ling Li , Alexander Gall , Richard Daifuku
IPC分类号： A61K31/70 , C07H19/167 , C07H19/173 , C07H19/20 , C12P19/40 , C12P19/30 , C12P19/34
CPC分类号： A61K31/708 , A61K31/7068 , A61K31/7072 , Y02A50/385
摘要： The present invention relates to methods of treating viral disease using mutagenic nucleoside analogs. In particular, the invention provides isoguanosine nucleosides and derivatives thereof as well a method of increasing the mutation rate of a virus such as bovine viral diarrhea virus (BVDV) and hepatitis C virus (HCV).
摘要翻译：本发明涉及使用致突变核苷类似物治疗病毒性疾病的方法。特别地，本发明提供异鸟嘌呤核苷及其衍生物，以及增加病毒如牛病毒性腹泻病毒（BVDV）和丙型肝炎病毒（HCV）的突变率的方法。

68. 发明授权

US09265837B1 5α-androstane-3β,5,6β-triol injection and preparation method therefor 有权
标题翻译： 5α-雄甾烷-3和bgr，5,6和三烯注射液及其制备方法
公开(公告)号：US09265837B1
公开(公告)日：2016-02-23
申请号：US14839869
申请日：2015-08-28
申请人： Guangmei Yan , Haiyan Hu , Jingxia Zhang , Pengxin Qiu , Ling Li , Ning Tian
发明人： Guangmei Yan , Haiyan Hu , Jingxia Zhang , Pengxin Qiu , Ling Li , Ning Tian
IPC分类号： A61K31/56 , A61K47/40 , A61K31/568 , A61K9/00
CPC分类号： A61K47/40 , A61K9/0019 , A61K31/565 , A61K31/568 , A61K47/6951 , B82Y5/00
摘要： A 5α-androstane-3β,5,6β-triol injection and its preparation are disclosed. The injection uses hydroxypropyl-β-cyclodextrin as a solubilizing agent and the active ingredient is present at a weight ratio of 1-20:40-500 to the hydroxypropyl-β-cyclodextrin. The injection may also comprise, by weight, 1-100 parts of at least one isotonic adjusting agent, 0-200 parts of at least one freeze drying filler, and 0-2000 parts of at least one solvent. The preparation method comprises dissolving hydroxypropyl-β-cyclodextrin solution, 5α-androstane-3β,5,6β-triol and at least one additional soluble excipient in water for injection in sequence to obtain a raw injection solution, and subjecting the raw injection solution to decolorization, depyrogenation, filtration and sterilization to obtain the injection. Drying the filtrate yields a solid for injection.
摘要翻译：公开了5α-雄甾烷-3＆bgr，5,6和三烯注射剂及其制备。注射剂使用羟丙基 - 环糊精作为增溶剂，活性成分以1-20:40-500的重量比与羟丙基-β-环糊精一起存在。注射剂还可以包含1-100份至少一种等渗调节剂，0-200份至少一种冷冻干燥填料和0-2000份至少一种溶剂。该制备方法包括将羟丙基 - 环糊精溶液，5α-雄甾烷-3β，5,6α-三醇和至少一种额外的可溶性赋形剂在水中依次溶解，得到原始注射液，注射溶液脱色，去热原，过滤和灭菌获得注射。干燥滤液得到固体，用于注射。

69. 发明授权

US09090889B2 Xylose isomerases and their uses 有权
标题翻译：木糖异构酶及其用途
公开(公告)号：US09090889B2
公开(公告)日：2015-07-28
申请号：US13948956
申请日：2013-07-23
申请人： David Neal Nunn, Jr. , Peter Luginbuhl , Ling Li , Adam Martin Burja , Jon Peter Flash Bartnek
发明人： David Neal Nunn, Jr. , Peter Luginbuhl , Ling Li , Adam Martin Burja , Jon Peter Flash Bartnek
IPC分类号： C12N9/90 , C12Q1/14 , C12P7/16 , C12P17/18 , C12P35/06 , C12P7/06 , C12P7/18 , C12P7/20 , C12P7/40 , C12P7/64 , C12P13/04 , C12N9/92
CPC分类号： C12N9/92 , C12N9/90 , C12P5/026 , C12P7/06 , C12P7/10 , C12P7/16 , C12P7/18 , C12P7/20 , C12P7/40 , C12P7/42 , C12P7/46 , C12P7/48 , C12P7/54 , C12P7/56 , C12P7/649 , C12P13/02 , C12P13/04 , C12P17/184 , C12P35/06 , C12P2203/00 , C12Y503/01005 , Y02E50/10 , Y02E50/13 , Y02E50/16 , Y02E50/17 , Y02E50/343
摘要： This disclosure relates to novel xylose isomerases and their uses, particularly in fermentation processes that employ xylose-containing media.
摘要翻译：本公开涉及新型木糖异构酶及其用途，特别是在使用含木糖的培养基的发酵过程中。

70. 发明授权

US08735567B2 Multi-targeted RNAi therapeutics for scarless wound healing of skin 有权
标题翻译：多靶点RNAi治疗用于皮肤无伤口伤口愈合
公开(公告)号：US08735567B2
公开(公告)日：2014-05-27
申请号：US12741645
申请日：2008-11-06
申请人： Patrick Y. Lu , Ling Li , Vera Simonenko
发明人： Patrick Y. Lu , Ling Li , Vera Simonenko
IPC分类号： C07H21/04 , C07H21/02 , A61K48/00
CPC分类号： A61K31/7105 , C12N15/1136 , C12N15/1138 , C12N2310/14
摘要： The present invention provides small interfering RNA (siRNA) molecules, compositions containing them, and methods of using them for improvement of skin scarless wound healing and other skin conditions, such as psoriasis and lupus-caused cutaneous lesions. The invention includes siRNA molecules and compositions containing them that inhibit the expression of one or more genes that promote pathological or undesired processes in wound healing and methods of using them.
摘要翻译：本发明提供小干扰RNA（siRNA）分子，含有它们的组合物，以及使用它们用于改善皮肤无伤口伤口愈合和其它皮肤状况的方法，例如牛皮癣和狼疮引起的皮肤损伤。本发明包括siRNA分子和含有它们的组合物，其抑制一种或多种促进伤口愈合中病理或不期望过程的基因的表达以及使用它们的方法。

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