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61. 发明授权

US5908844A N-substituted azabicycloalkane derivatives, their preparation and use 失效
标题翻译： N-取代的氮杂双环烷烃衍生物，其制备和用途
公开(公告)号：US5908844A
公开(公告)日：1999-06-01
申请号：US640751
申请日：1996-05-06
申请人： Gerd Steiner , Rainer Munschauer , Liliane Unger , Hans-Jurgen Teschendorf , Thomas Hoger
发明人： Gerd Steiner , Rainer Munschauer , Liliane Unger , Hans-Jurgen Teschendorf , Thomas Hoger
IPC分类号： A61K31/40 , A61K31/435 , A61P25/00 , A61P25/02 , A61P25/20 , A61P25/24 , A61P25/26 , C07D403/06 , C07D487/04 , C07D513/04 , A61K31/505 , C07D403/04
CPC分类号： C07D403/06 , C07D487/04 , C07D513/04
摘要： Compounds of the formula I ##STR1## where B, R.sup.1, R.sup.2, n, R.sup.3, A, X, Y and Z have the meanings stated in the description, and their preparation are described. The novel ompounds are suitable for controlling diseases.
摘要翻译： PCT No.PCT / EP94 / 03583第 371日期：1996年5月6日 102（e）日期1996年5月6日PCT 1994年10月31日PCT PCT。公开号WO95 / 13279 日期：1995年5月18日公式I的化合物，其中B，R1，R2，n，R3，A，X，Y和Z具有说明书中所述的含义及其制备。这种新颖的症状适用于控制疾病。

62. 发明授权

US5753690A N-substituted azobicycloheptane derivatives, the preparation and use thereof 失效
标题翻译： N-取代偶氮二环庚烷衍生物，其制备及应用
公开(公告)号：US5753690A
公开(公告)日：1998-05-19
申请号：US776583
申请日：1997-02-03
申请人： Gerd Steiner , Rainer Munschauer , Thomas Hoger , Liliane Unger , Hans-Jurgen Teschendorf
发明人： Gerd Steiner , Rainer Munschauer , Thomas Hoger , Liliane Unger , Hans-Jurgen Teschendorf
IPC分类号： C07D409/12 , A61K31/40 , A61K31/403 , A61P25/18 , A61P43/00 , C07D209/44 , C07D209/52 , C07D209/92 , C07D403/06 , C07D209/02 , C07D209/56
CPC分类号： C07D403/06 , C07D209/52 , C07D209/92
摘要： A compound of the formula ##STR1## in which A, R.sup.1 and n have the meanings stated in the description are described. The novel compounds are suitable for controlling diseases.
摘要翻译： PCT No.PCT / EP95 / 02912 Sec。 371日期1997年2月3日 102（e）日期1997年2月3日PCT提交1995年7月22日PCT公布。出版物WO96 / 04245 日期1996年2月15日描述了其中A，R 1和n具有说明书中所述含义的式“IMAGE”的化合物。新型化合物适用于控制疾病。

63. 发明授权

US4866057A 4-substituted 10-cyanomethylenepyrrolo[4,3-e]-benzazepines 失效
标题翻译： 4-取代的10-氰基亚甲基吡咯并[4,3-e] - 苯并氮杂
公开(公告)号：US4866057A
公开(公告)日：1989-09-12
申请号：US196606
申请日：1988-05-20
申请人： Gerd Steiner , Juergen Pfister , Hans-Juergen Teschendorf , Liliane Unger , Rudolf Binder
发明人： Gerd Steiner , Juergen Pfister , Hans-Juergen Teschendorf , Liliane Unger , Rudolf Binder
IPC分类号： A61K31/55 , A61P21/02 , A61P25/00 , A61P25/02 , A61P25/20 , C07D487/04
CPC分类号： C07D487/04
摘要： Compounds of the formula ##STR1## where R.sup.1, R.sup.2, R.sup.3, R.sup.4 and A have the meanings stated in the specification, as well as the use thereof for controlling diseases, are described.
摘要翻译：其中R1，R2，R3，R4和A具有本说明书中所述含义的式“IMAGE”的化合物及其用于控制疾病的用途。

64. 发明授权

US4857658A Preparation of (Z)-2-(2-arylethenyl)arylcarboxylic acids 失效
标题翻译：（Z）-2-（2-芳基乙烯基）芳基羧酸的制备
公开(公告)号：US4857658A
公开(公告)日：1989-08-15
申请号：US134108
申请日：1987-12-17
申请人： Marco Thyes , Gerd Steiner
发明人： Marco Thyes , Gerd Steiner
IPC分类号： C07C63/331 , C07C51/00 , C07C51/353 , C07C63/66 , C07C63/74 , C07C65/28 , C07C67/00 , C07C201/00 , C07C205/06 , C07C205/56 , C07C253/00 , C07C255/50 , C07C255/57
CPC分类号： C07C51/353
摘要： (Z)-2-(2-arylethenyl)arylcarboxylic acids of the general formula I ##STR1## where A is a group for completing an aromatic ring system and Ar is an aromatic radical, are prepared by reacting a 2-formylarylcarboxylic acid of the general formula II ##STR2## with an (arylmethyl)phosphonium salt of the general formula III ##STR3## where R.sup.1, R.sup.2 and R.sup.3 are each organic radicals and X is halogen, in the presence of a base at from (-20.degree.) to +30.degree. C. by carrying out the reaction in the presence of a C.sub.1 -C.sub.5 -alkanol and/or a C.sub.2 -C.sub.4 -alkanediol.
摘要翻译：（I）的（Z）-2-（2-芳基乙烯基）芳基羧酸，其中A是用于完成芳族环系统的基团，Ar是芳族基团，其通过使2-甲酰基芳基羧酸通式II（II）的酸与通式III（III）的（芳基甲基）鏻盐反应，其中R 1，R 2和R 3各自为有机基团，X为卤素，在通过在C1-C5链烷醇和/或C 2 -C 4 - 链烷二醇的存在下进行反应，从（-20℃）至+ 30℃进行反应。

65. 发明授权

US4745111A Anti-anxiety, anti-agitation, and anti-sleepless states 4-substituted 10-cyanomethylenethieno-[4,3-e]benzoazepine derivatives, compositions, and methods of use therefor 失效
标题翻译：抗焦虑，抗焦虑和抗睡眠状态4-取代的10-氰基亚甲基 - 乙烯基 - [4,3-e]苯并氮杂衍生物，组合物及其使用方法
公开(公告)号：US4745111A
公开(公告)日：1988-05-17
申请号：US883628
申请日：1986-07-09
申请人： Gerd Steiner , Hans-Juergen Teschendorf , Liliane Unger
发明人： Gerd Steiner , Hans-Juergen Teschendorf , Liliane Unger
IPC分类号： A61K31/55 , A61P25/00 , A61P25/08 , A61P25/20 , C07D495/04 , C07D223/14 , C07D223/16
CPC分类号： C07D495/04
摘要： Compounds of the formula ##STR1## where R and A have the meanings given in the description, and their use in the treatment of disorders are described.
摘要翻译：其中R和A具有说明书中给出的含义的式“IMAGE”的化合物及其在治疗疾病中的用途。

66. 发明授权

US4586148A Arrangement for scanning printing plates 失效
标题翻译：扫描印版的安排
公开(公告)号：US4586148A
公开(公告)日：1986-04-29
申请号：US500612
申请日：1983-06-03
申请人： Jurgen Rehder , Siegfried Schuhmann , Gerd Steiner
发明人： Jurgen Rehder , Siegfried Schuhmann , Gerd Steiner
IPC分类号： B41F31/02 , B41F33/00 , G01B11/28 , B41M1/00 , G06F15/40
CPC分类号： B41F33/0027 , Y10S101/46
摘要： A machine for scanning printing plates to determine the ratio of "printing" to "non-printing" area for pre-adjustment of the ink dosing elements of a printing machine has an array of electronic photo-sensors, each sensor being disposed in a channel having low-reflection chambers which permit sharp delimination of resolution elements on the printing plate and ensure high definition scanning of different types of printing plates under practical conditions. Preferably the diaphragms dividing the channel into chambers have greater spacing at greater distances from the element sensed on the printing plate. To accommodate printing plates of different materials, means are provided for selecting the wave length of the light source. To prevent measurement error due to changes in the distance from the printing plate to the light source and sensor array, the photosensor array is preferably directed or aimed 60.degree. to 45.degree. with respect to the normal vector of the printing plate, and the light source is in the same quadrant as the photo-sensor array at an angle of 0.degree. to 45.degree. with respect to the normal vector. Automatic calibration, automatic printing plate size determination, automatic sensing of identification information engraved on the printing plate, and a stairstep scan to increase the scanning rate are provided by suitable procedures executed by a microcomputer controlling the scanning process and analyzing, adjusting, and interpreting data received from the sensor array.
摘要翻译：用于扫描印版以确定“印刷”与“非印刷”区域的比例的机器用于预先调整印刷机的墨水计量元件的阵列具有电子光电传感器阵列，每个传感器设置在通道中具有低反射室，其允许印刷板上的分辨率元件的清晰划分，并且确保在实际条件下对不同类型印刷版的高清晰度扫描。优选地，将通道分成腔室的隔膜在距离印刷板上感测的元件更远的距离处具有更大的间隔。为了适应不同材料的印版，提供了用于选择光源的波长的装置。为了防止由于从印版到光源和传感器阵列的距离变化而引起的测量误差，光传感器阵列优选地相对于印版的法向量指向或瞄准60°至45°，光源与光电传感器阵列相对于法向量以0°至45°的角度位于同一象限内。通过自动校准，自动印版尺寸确定，刻印在印版上的识别信息的自动识别以及增加扫描速度的平面扫描，由控制扫描过程的微机执行的合适程序提供，并分析，调整和解释数据从传感器阵列接收。

67. 发明授权

US4502386A Ink fountain having temperature responsive element 失效
标题翻译：喷墨机具有温度响应元件
公开(公告)号：US4502386A
公开(公告)日：1985-03-05
申请号：US494172
申请日：1983-05-13
申请人： Bert Cappel , Helmut Kerber , Siegfried Schuhmann , Gerd Steiner
发明人： Bert Cappel , Helmut Kerber , Siegfried Schuhmann , Gerd Steiner
IPC分类号： B41F31/02 , B41F31/04 , B41F31/06 , B41L27/08
CPC分类号： B41F31/04
摘要： An ink fountain for a printing press has a temperature-responsive element for compensating the adjustment of the spacing between the blade and the fountain roller to keep the thickness of the ink film fed by the blade substantially constant even under extreme temperature variations. The sub-frame of the ink fountain is pivotally mounted to the main frame of the printing press about a pivot axis generally parallel to the axis of the fountain roller, and the pivot angle is a function of the thermal expansion of the temperature-responsive element. In one preferred embodiment, the temperature-responsive element is elongated, received in a guide fixed to the sub-frame, and has a free end bearing against the bearing bushing of the fountain roller. In another embodiment, the temperature-responsive element is a side wall of the ink trough or is a plate parallel to the side wall of the ink trough, and rollers are journaled to the temperature-responsive element and bear against the surface of the fountain roller. In either embodiment, the temperature-responsive element is pre-stressed by a pull rod tending to pivot the sub-frame so that the temperature-responsive element bears against the sub-frame and the main frame.
摘要翻译：用于印刷机的墨斗具有温度响应元件，用于补偿叶片和墨斗辊之间的间隔的调节，以便即使在极端温度变化下也能保持由叶片供给的墨膜的厚度基本恒定。墨斗的子框架围绕基本上平行于墨斗辊的轴线的枢转轴线可枢转地安装到印刷机的主框架上，并且枢转角度是温度响应元件的热膨胀的函数。在一个优选实施例中，温度响应元件是细长的，容纳在固定到子框架上的导向件中，并且具有抵靠供墨辊的轴承衬套的自由端轴承。在另一个实施例中，温度响应元件是墨槽的侧壁或平行于墨槽的侧壁的板，并且辊与轴承温度响应元件并且抵靠在墨斗辊的表面上。在任一实施例中，温度响应元件由倾斜杆预先施加压力，拉杆使副框架枢转，使得温度响应元件抵靠在副框架和主框架上。

68. 发明授权

US4399137A 6-Imidazol-1-yl-3-hydrazino-pyridazines, their preparation and antihypertensive use 失效
标题翻译： 6-咪唑-1-基-3-肼基 - 哒嗪，其制备和抗高血压用途
公开(公告)号：US4399137A
公开(公告)日：1983-08-16
申请号：US330374
申请日：1981-12-14
申请人： Gerd Steiner , Josef Gries , Dieter Lenke
发明人： Gerd Steiner , Josef Gries , Dieter Lenke
IPC分类号： C07D403/04 , A61K31/50 , A61P9/12 , C07D521/00
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08
摘要： 6-Imidazol-1-yl-3-hydrazino-pyridazines, in which the imidazole ring is unsubstituted or is substituted by halogen or alkyl, their physiologically tolerated addition salts with acids, processes for their preparation and their use as drugs in the treatment of hypertonia.
摘要翻译： 6-咪唑-1-基-3-肼基 - 哒嗪，其中咪唑环未被取代或被卤素或烷基取代，其与酸的生理上耐受的加成盐，其制备方法及其作为治疗药物的用途高血压

69. 发明授权

US4388237A 6(1-Piperazinyl), piperidino and (1(homopiperazinyl)11-cyanomethylene morphanthridines 失效
标题翻译： 6（1-哌嗪基），哌啶子基和（1（高哌嗪基）11-氰基亚甲基吗啉
公开(公告)号：US4388237A
公开(公告)日：1983-06-14
申请号：US147538
申请日：1980-05-07
申请人： Gerd Steiner , Albrecht Franke , Dieter Lenke , Hans-Juegen Teschendorf , Wolfgang Worstmann , Horst Kreiskott
发明人： Gerd Steiner , Albrecht Franke , Dieter Lenke , Hans-Juegen Teschendorf , Wolfgang Worstmann , Horst Kreiskott
IPC分类号： A61K31/55 , A61P25/18 , C07D223/20 , C07D403/04 , C07D401/04 , C07D403/06
CPC分类号： C07D223/20
摘要： 6-Substituted 11-alkylene-morphanthridines, also referred to as 11-alkylene-dibenzo[b,e]-azepines, their pure cis- and trans-isomers, processes for their preparation, and therapeutic agents containing these compounds, which may be used as drugs, in particular neuroleptics, sedatives, hypnotics, analgesics, antidepressants or agents for treating Parkinson's syndrome.
摘要翻译： 6-取代的11-亚烷基 - 吗啉，也称为11-亚烷基 - 二苯并[b，e] - 吖庚因，它们的纯顺式和反式异构体，其制备方法和含有这些化合物的治疗剂，其可以是用作药物，特别是精神安定药，镇静剂，催眠药，镇痛药，抗抑郁药或治疗帕金森综合征的药剂。

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