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61. 发明公开

EP2655212A1 KINDERSICHERE HOCHINERTE BEUTELVERPACKUNG FÜR EINZELDOSIERTE WIRKSTOFFHALTIGE FILME 审中-公开
标题翻译：儿童安全包装高度惰性袋含有活性薄膜单剂量
公开(公告)号：EP2655212A1
公开(公告)日：2013-10-30
申请号：EP11819089.1
申请日：2011-12-21
申请人： LTS LOHMANN Therapie-Systeme AG
发明人： KRUMME, Markus , BEHREND, Grace, A. , DODD, Steven
IPC分类号： B65D75/58
CPC分类号： B65D75/5833 , A61J1/00 , B65D2221/00
摘要： The invention relates to a childproof packaging for individual doses (1), in particular for preparations for administration in film form, wherein the packaging constitutes a bag produced by sealing, which has at least on each side a covering layer which is provided at least on one side with local weak points (4) which do not touch the edge of the packaging, wherein the local weak points (4) form a cohesive pattern which runs around the individual dose (1) in an arc or a curve and overlaps an angular region of at least 90° when considered from the main area of the individual dose (1).

62. 发明授权

EP1799579B1 PEELFÄHIGE, KINDERSICHERE VERPACKUNG FÜR FILMFÖRMIGE ARZNEIFORMEN 有权
标题翻译：可剥，儿童安全包装FOR膜状药剂型
公开(公告)号：EP1799579B1
公开(公告)日：2012-10-31
申请号：EP05787419.0
申请日：2005-09-10
申请人： LTS LOHMANN Therapie-Systeme AG
发明人： SIMON, Michael , KRUMME, Markus , LUDWIG, Karin , ASMUSSEN, Bodo
IPC分类号： B65D50/06 , B65D75/36
CPC分类号： B65D50/06 , B65D75/5805 , B65D2215/04 , B65D2575/362

63. 发明公开

EP2396241A1 KINDERGESICHERTE, HOCHINERTE EINZELVERPACKUNG 有权
标题翻译：儿童防护，高惰性单套
公开(公告)号：EP2396241A1
公开(公告)日：2011-12-21
申请号：EP10702621.3
申请日：2010-02-03
申请人： LTS LOHMANN Therapie-Systeme AG
发明人： KRUMME, Markus
IPC分类号： B65D75/58
CPC分类号： B31B41/00 , A61J1/03 , B31B70/00 , B31B2160/00 , B65D75/5805 , Y10T29/4998
摘要： The present invention relates to individual dose packagings (1) for transdermal therapeutic systems or film-like forms of administration in the form of a sealing edge bag that can be peeled back with a complete surrounding and continuous sealing surface, comprising two packaging material elements, that are arranged on top of each other and form the upper side and the bottom side of a bag containing the product, wherein at least one layer of the packaging material elements is a metal layer and at least one packaging material element a film laminate with an at least three-layer design; and the outer layer of the at least three-layer film laminate has a minimum tear resistance of 30 N, wherein said outer layer comprises at least one line-shaped weakening (20, 21) that is not touching the edge of the packaging on the upper and bottom side and the line-shaped weakening has a reduced resistance to tear for opening the packaging. The invention further relates to a method for the production thereof.

64. 发明授权

EP1560564B1 MEHRSCHICHTIGES TRANSMUCOSALES THERAPEUTISCHES SYSTEM 有权
标题翻译：多层粘膜治疗系统
公开(公告)号：EP1560564B1
公开(公告)日：2008-01-02
申请号：EP03773702.0
申请日：2003-11-04
申请人： LTS LOHMANN Therapie-Systeme AG
发明人： KRUMME, Markus
IPC分类号： A61K9/00
CPC分类号： A61K9/7092 , A61K9/006 , A61K9/7007
摘要： The invention relates to a film-type therapeutic system (1) comprising at least two interconnected layers, for the transmucosal administration of active ingredients. Said system comprises a layer (2) which is mucoadhesive in an aqueous environment, and a single-layer or multi-layer rear layer (3). At least one of said layers contains active ingredients, and the cited mucoadhesive layer (2) is capable of swelling in aqueous media, but is insoluble or only slightly soluble.

65. 发明公开

EP1863444A2 WAFER ENTHALTEND STEROIDHORMONE 有权转让
标题翻译： WAFER含类固醇激素
公开(公告)号：EP1863444A2
公开(公告)日：2007-12-12
申请号：EP06723435.1
申请日：2006-03-15
申请人： LTS LOHMANN Therapie-Systeme AG , Bayer Schering Pharma Aktiengesellschaft
发明人： KRUMME, Markus , RADLMAIER, Albert , GENERAL, Sascha , DITTGEN, Michael , JENSEN, Keith
IPC分类号： A61K9/00
CPC分类号： A61K31/56 , A61K31/568
摘要： The invention concerns a pharmaceutical composition in the form of a film-shaped system for transmucosal delivery of steroid hormones. The invention concerns in particular a system for delivering steroid hormones which dissolves in the oral cavity and releases the active substances with high bioavailability. Said film-shaped delivery system dissolves in the oral cavity preferably in less than 30 minutes, the steroid hormone which passes through the trasmucosal route of the delivery system to a blood circuit rapidly increasing concentration in the blood. The steroid hormone concentration in the blood can reach a maximum level in less than 60 minutes after delivery.

66. 发明授权

EP1227802B1 FILMFÖRMIGE ZUBEREITUNG ZUR BIPHASIGEN FREISETZUNG PHARMAKOLOGISCH WIRKSAMER ODER ANDERER SUBSTANZEN 有权
标题翻译：膜状制剂FOR RELEASE双相PHARMACOLOGICALL有效或其他物质
公开(公告)号：EP1227802B1
公开(公告)日：2006-03-15
申请号：EP00975993.7
申请日：2000-11-03
申请人： LTS LOHMANN Therapie-Systeme AG
发明人： LUDWIG, Karin , KRUMME, Markus
IPC分类号： A61K9/70 , A61K9/20
CPC分类号： A61K9/7007 , A61K9/2072 , A61K9/209
摘要： The invention relates to a polymer-based film preparation, for biphasic release of substances contained therein, into a liquid environment. Said film preparation is characterised in that it comprises at least two polymer matrix layers, which differ in the polymer composition thereof, whereby the release from one layer occurs rapidly and the release from at least one further layer occurs slowly.

67. 发明公开

EP1425229A1 BEHÄLTER MIT SCHIEBEDECKEL 有权
标题翻译： BEHÄLTERMIT SCHIEBEDECKEL
公开(公告)号：EP1425229A1
公开(公告)日：2004-06-09
申请号：EP02797575.4
申请日：2002-08-13
申请人： LTS Lohmann Therapie-Systeme AG
发明人： KRUMME, Markus
IPC分类号： B65D43/20 , B65D83/08
CPC分类号： B65D43/20 , A45C5/065 , A45C11/18 , B65D2583/082
摘要： The invention relates to a container for storing and providing stacked film-like or sheet-like materials. The container is comprised of a pan, which accommodates the stacked materials and has a bottom and closed lateral walls joined thereto, and of a tightly sealing cover that at least partially encloses said pan. To this end, the cover is provided in the form of a slide cover. Both sides of the pan and of the slide cover are provided, parallel to their longitudinal direction, with parallel guide elements. All lateral walls of the pan have, up to the slide cover, a closed pan sealing surface that encircles the pan opening. The slide cover encompasses, at least in part or in areas, three lateral walls and the bottom or corresponding guide elements of the pan, whereby two of these lateral walls are oriented parallel to the longitudinal direction. A cover sealing surface is provided in the slide cover and rests upon the pan sealing surface when the container is closed. The invention provides a container for film-like or sheet-like materials, which can be repeatedly opened and ensures a high sealing function with regard to gases, moisture and aromas while having a simple design.
摘要翻译：本发明涉及用于存储和提供堆叠的薄膜状或片状材料的容器。该容器由容纳堆叠的材料并具有与其连接的底部和封闭的侧壁的盘以及至少部分地包围所述盘的紧密密封的盖组成。为此，盖子以滑盖的形式提供。平底锅和滑盖的两侧与其纵向方向平行地设置有平行的导向元件。盘的所有侧壁都具有直到滑盖的围绕盘开口的封闭的盘密封表面。滑盖至少部分地或部分地包围锅的三个侧壁以及底部或相应的导向元件，其中两个侧壁平行于纵向定向。盖子密封表面设置在滑盖中，并且当容器关闭时搁置在盖子密封表面上。本发明提供了一种用于膜状或片状材料的容器，该容器可以重复打开并确保对于气体，水分和香味的高密封功能，同时具有简单的设计。

68. 发明公开

EP1227799A2 EINE FILM-, FOLIEN- ODER OBLATENFÖRMIGE ZUBEREITUNG 有权
标题翻译：的膜，片或晶片形的制备
公开(公告)号：EP1227799A2
公开(公告)日：2002-08-07
申请号：EP00977481.1
申请日：2000-11-03
申请人： LTS Lohmann Therapie-Systeme AG
发明人： LUDWIG, Karin , KRUMME, Markus
IPC分类号： A61K9/20 , A61K9/70
CPC分类号： A61K9/2072 , A61K9/70
摘要： The invention relates to a film, sheet or wafer-shaped preparation for administering substances with a taste or smell-related and/or caring and/or healing effect, in which these substances are identified by a code in the form of written or graphic markings or patterns. Said code is configured in the form of surface areas of different thickness. The invention is characterised in that the preparation comprises two differently coloured adjacent layers with complementary surface areas of different thickness.

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