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61. 发明授权

US07025719B2 Metallic cardiac support device 有权
标题翻译：金属心脏支持装置
公开(公告)号：US07025719B2
公开(公告)日：2006-04-11
申请号：US10809961
申请日：2004-03-26
申请人： Clifton A. Alferness , Jai Shankar Raman , John Melmouth Power
发明人： Clifton A. Alferness , Jai Shankar Raman , John Melmouth Power
IPC分类号： A61F2/04 , A61B19/00
CPC分类号： A61F2/2481 , A61F2002/0068
摘要： A jacket of biological compatible material has an internal volume dimensioned for an apex of the heart to be inserted into the volume and for the jacket to be slipped over the heart. The jacket has a longitudinal dimension between upper and lower ends sufficient for the jacket to surround a lower portion of the heart with the jacket surrounding a valvular annulus of the heart and further surrounding the lower portion to cover at least the ventricular lower extremities of the heart. The jacket is adapted to be secured to the heart with the jacket surrounding at least the valvular annulus and the ventricular lower extremities. The jacket is adjustable on the heart to snugly conform to an external geometry of the heart and assume a maximum adjusted volume for the jacket to constrain circumferential expansion of the heart beyond the maximum adjusted volume during diastole and to permit unimpeded contraction of the heart during systole.
摘要翻译：生物相容材料的护套具有尺寸设计用于心脏顶点的内部容积，以将其插入体积中并使护套滑过心脏。护套具有在上下端之间的纵向尺寸，足以使护套围绕心脏的下部围绕心脏的瓣膜环并且进一步围绕下部以至少覆盖心脏的心室下端。护套适于固定在心脏上，护套至少围绕瓣膜环和心室下肢。护套在心脏上是可调节的，以贴合地符合心脏的外部几何形状，并假设护套的最大调节体积以约束舒张期心脏超过最大调节体积的周向扩张，并允许心脏收缩期间不受阻碍的收缩。

62. 发明授权

US06567699B2 Defibrillating cardiac constraint 有权
公开(公告)号：US06567699B2
公开(公告)日：2003-05-20
申请号：US10060655
申请日：2002-01-30
申请人： Clifton A. Alferness , James Edward Shapland
发明人： Clifton A. Alferness , James Edward Shapland
IPC分类号： A61N139
CPC分类号： A61N1/0563 , A61F2/2481 , A61F2002/0068
摘要： A device for treating cardiac disease of a heart includes a jacket of flexible material defining a volume between an open upper end and a lower end. The jacket is dimensioned for an apex of the heart to be inserted into the volume through the open upper end and for the jacket to be slipped over the heart. The jacket is adapted to be secured to the heart with the jacket having portions disposed on opposite sides of the heart. The jacket is adjustable to snugly conform to an external geometry of the heart and to constrain circumferential expansion of the heart during diastole and permit substantially unimpeded contraction of the heart during systole. A first and a second grid of electrodes are carried on the jacket. The grids are disposed to be in overlying relation to individual ones of the opposite sides of the heart when the jacket is secured to the heart. The first and second grids are connectable to a source of a defibrillating waveform.

63. 发明授权

US06482146B1 Cardiac disease treatment and device 有权
标题翻译：心脏病治疗及器械
公开(公告)号：US06482146B1
公开(公告)日：2002-11-19
申请号：US09593251
申请日：2000-06-13
申请人： Clifton A. Alferness , Donald G. Rohrbaugh , J. Edward Shapland , Michael J. Girard , Donald F. Palme, II , James E. Cox
发明人： Clifton A. Alferness , Donald G. Rohrbaugh , J. Edward Shapland , Michael J. Girard , Donald F. Palme, II , James E. Cox
IPC分类号： A61F200
CPC分类号： A61F2/2481 , Y10S623/904
摘要： A jacket of biological compatible material has an internal volume dimensioned for an apex of the heart to be inserted into the volume and for the jacket to be slipped over the heart. The jacket has a longitudinal dimension between upper and lower ends sufficient for the jacket to surround a lower portion of the heart with the jacket surrounding a valvular annulus of the heart and further surrounding the lower portion to cover at least the ventricular lower extremities of the heart. The jacket is adapted to be secured to the heart with the jacket surrounding at least the valvular annulus and the ventricular lower extremities. The jacket is adjustable on the heart to snugly conform to an external geometry of the heart and assume a maximum adjusted volume for the jacket to constrain circumferential expansion of the heart beyond the maximum adjusted volume during diastole and to permit unimpeded contraction of the heart during systole.
摘要翻译：生物相容材料的护套具有尺寸设计用于心脏顶点的内部容积，以将其插入体积中并使护套滑过心脏。护套具有在上下端之间的纵向尺寸，足以使护套围绕心脏的下部围绕心脏的瓣膜环并且进一步围绕下部以至少覆盖心脏的心室下端。护套适于固定在心脏上，护套至少围绕瓣膜环和心室下肢。护套在心脏上是可调节的，以贴合地符合心脏的外部几何形状，并假设护套的最大调节体积以约束舒张期心脏超过最大调节体积的周向扩张，并允许心脏收缩期间不受阻碍的收缩。

64. 发明授权

US06375608B1 Cardiac reinforcement device 有权
公开(公告)号：US06375608B1
公开(公告)日：2002-04-23
申请号：US09696651
申请日：2000-10-25
申请人： Clifton A. Alferness
发明人： Clifton A. Alferness
IPC分类号： A61B1900
CPC分类号： A61F2/2481 , A61F2002/2484 , A61F2250/0003 , A61M1/1008 , A61M1/106 , A61M1/1068 , A61M1/12
摘要： The present disclosure is directed to a cardiac reinforcement device (CRD) and method for the treatment of cardiomyopathy. The CRD provides for reinforcement of the walls of the heart by constraining cardiac expansion, beyond a predetermined limit, during diastolic expansion of the heart. A CRD of the invention can be applied to the epicardium of the heart to locally constrain expansion of the cardiac wall or to circumferentially constrain the cardiac wall during cardiac expansion.

65. 发明授权

US06258100B1 Method of reducing lung size 有权
标题翻译：减少肺大小的方法
公开(公告)号：US06258100B1
公开(公告)日：2001-07-10
申请号：US09686204
申请日：2000-10-10
申请人： Clifton A. Alferness , Richard Y. Lin , Wilfred E. Jaeger
发明人： Clifton A. Alferness , Richard Y. Lin , Wilfred E. Jaeger
IPC分类号： A61F1100
CPC分类号： A61F2/04 , A61B17/12104 , A61B17/12172 , A61F2/24 , A61F2002/043
摘要： A device, system, and method provides for lung size reduction by permanently collapsing at least a portion of a lung. The lung portion may be collapsed by obstructing the air passageway which communicates the lung portion to be collapsed. The air passageway may be obstructed by an obstructing member which precludes airflow in either direction or with a one-way valve which permits air to be exhaled from the lung portion while precluding air from being inhaled into the lung portion. In addition, a vacuum may be pulled within the lung portion to be collapsed for collapsing the lung portion and while the lung portion is collapsed the obstructing member may be placed in the air passageway to maintain the lung portion in a permanently collapsed state.
摘要翻译：装置，系统和方法通过永久地塌缩至少一部分肺而提供肺尺寸减小。肺部分可以通过阻塞连通待收缩的肺部分的空气通道而折叠。空气通道可能被妨碍任何一个方向气流的阻塞构件阻塞，或者阻止空气被吸入肺部的单向阀，从而允许空气从肺部呼出。此外，真空可以在肺部分内被拉动以被塌缩以塌陷肺部，而当肺部收缩时，阻塞构件可以放置在空气通道中，以保持肺部分处于永久塌陷状态。

66. 发明授权

US06241654B1 Cardiac reinforcement devices and methods 有权
标题翻译：心脏加强装置及方法
公开(公告)号：US06241654B1
公开(公告)日：2001-06-05
申请号：US09348697
申请日：1999-07-07
申请人： Clifton A. Alferness
发明人： Clifton A. Alferness
IPC分类号： A61F200
CPC分类号： A61F2/2481
摘要： The present disclosure is directed to materials, devices, and methods for treatment of cardiac conditions including, for example, cardiomyopathy and valvular insufficiency. The devices and methods are directed to constraining expansion of the heart during diastole to a predetermined limit. In one embodiment, a material of the invention is a weave material that can be applied to the heart as a wrap of a two-dimensional sheet or shaped into a jacket. A cardiac reinforcement device of the invention can be applied to the heart to constrain cardiac expansion to a predetermined limit.
摘要翻译：本公开涉及用于治疗心脏病症的材料，装置和方法，包括例如心肌病和瓣膜功能不全。装置和方法旨在将心脏舒张期的扩张约束到预定极限。在一个实施方案中，本发明的材料是可以作为二维片的包裹物或成形为外套的心脏施加的编织材料。本发明的心脏增强装置可以应用于心脏以将心脏扩张限制到预定极限。

67. 发明授权

US5332400A Atrial defibrillator and method for providing pre-cardioversion warning 失效
标题翻译：心房除颤器及提供心律前期警示的方法
公开(公告)号：US5332400A
公开(公告)日：1994-07-26
申请号：US996656
申请日：1992-12-24
申请人： Clifton A. Alferness
发明人： Clifton A. Alferness
IPC分类号： A61N1/39 , A61B5/04
CPC分类号： A61N1/3925 , A61N1/395
摘要： An implantable atrial defibrillator provides cardioverting electrical energy to the atria of a patient's heart in need of cardioversion and a precardioversion warning to the patient. The atrial defibrillator includes a detector for detecting atrial activity of the patient's heart, and an atrial fibrillation detector responsive to the atrial activity detector for determining when the atria of the patient's heart are in need of cardioversion. A cardioverter responsive to the atrial fibrillation detector, applies warning electrical energy to the atria of the patient's heart when the atria are in need of cardioversion and thereafter applies cardioverting electrical energy to the atria. The warning electrical energy is of insufficient quantity to intentionally cardiovert the atria but of sufficient quantity so as to be discernable by the patient.
摘要翻译：可植入心房除颤器为需要心脏复律的患者心脏的心房提供心脏转复电能，并向患者提供预防心律失常警告。心房除颤器包括用于检测患者心脏的心房活动的检测器，以及响应于心房活动检测器的心房颤动检测器，用于确定患者心脏的心房何时需要心脏复律。响应于心房颤动检测器的心律转复器在心房需要心脏复律时向患者心脏的心房施加警告电能，然后将心电转移电能施加到心房。预警电能数量不足以故意心跳心房但足够数量，以便患者辨别。

68. 发明申请

US20170014132A9 TRANSESOPHAGEAL GASTRIC REDUCTION METHOD AND DEVICE FOR REDUCING THE SIZE OF A PREVIOUSLY FORMED GASTRIC REDUCTION POUCH 审中-公开
标题翻译：用于减少先前形成的减少气泡的尺寸的透气性减少方法和装置
公开(公告)号：US20170014132A9
公开(公告)日：2017-01-19
申请号：US13726525
申请日：2012-12-24
申请人： Steve G. BAKER , Raymond Michael Wolniewicz, III , Sean Totten , Clifton A. Alferness , Scott Harshman
发明人： Steve G. BAKER , Raymond Michael Wolniewicz, III , Sean Totten , Clifton A. Alferness , Scott Harshman
IPC分类号： A61B17/11 , A61B19/00
CPC分类号： A61B17/11 , A61B17/0401 , A61B34/30 , A61B90/00 , A61B2017/00349 , A61B2017/00818 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/306 , A61F5/0079 , A61F5/0086
摘要： A gastric reduction pouch of a stomach is formed by gathering stomach tissue circumferentially from within the stomach to form a reduced diameter stomach section. A plurality of fasteners are deployed within the gathered stomach tissue to maintain the reduced diameter stomach portion. The gathering step may include folding the stomach tissue to produce a plurality of stomach tissue folds. A device is disclosed that is particularly adapted to permit such gastric reduction of a previously formed gastric reduction pouch.
摘要翻译：通过从胃内周向聚集胃部组织形成缩小的胃部部分来形成胃的胃减压袋。多个紧固件部署在聚集的胃组织内以保持直径缩小的胃部分。收集步骤可以包括折叠胃组织以产生多个胃组织褶皱。公开了一种特别适于允许先前形成的胃减压袋的胃部还原的装置。

69. 发明授权

US08956319B2 One-way valve devices for anchored implantation in a lung 有权
标题翻译：用于锚定植入肺部的单向阀装置
公开(公告)号：US08956319B2
公开(公告)日：2015-02-17
申请号：US13554987
申请日：2012-07-20
申请人： David H. Dillard , Hugo X. Gonzalez , Seung Yi , Lauri J. DeVore , Mia Park , Dean T. Corcoran , Jenni Rimbaugh , Clifton A. Alferness
发明人： David H. Dillard , Hugo X. Gonzalez , Seung Yi , Lauri J. DeVore , Mia Park , Dean T. Corcoran , Jenni Rimbaugh , Clifton A. Alferness
IPC分类号： A61M5/00 , A61B17/12 , A61F2/24 , A61F2/04
CPC分类号： A61B17/12104 , A61B17/12172 , A61B2017/00809 , A61F2/24 , A61F2002/043
摘要： An intra-bronchial device placed and anchored in an air passageway of a patient to collapse a lung portion associated with the air passageway. The device includes a support structure, an obstructing member carried by the support structure that reduces ventilation to the lung portion by preventing air from being inhaled into the lung portion, and at least one anchor carried by the support structure that anchors the obstruction device within the air passageway. The anchor may engage the air passageway wall by piercing or friction, include a stop dimensioned for limiting the piercing of the air passageway wall, and may be releasable from the air passageway for removal of the intra-bronchial device. The anchors may be carried by a peripheral portion of the support structure, or by a central portion of the support structure. The obstructing member may be a one-way valve.
摘要翻译：将支气管内装置放置并锚定在患者的空气通道中以折叠与空气通道相关联的肺部分。该装置包括支撑结构，由支撑结构承载的阻塞构件，其通过防止空气被吸入肺部而减少对肺部的通气，以及由支撑结构承载的至少一个锚固件，其将阻塞装置锚定在内部空气通道。锚固件可以通过穿孔或摩擦接合空气通道壁，包括尺寸适于限制空气通道壁的刺穿的止挡件，并且可以从空气通道释放以去除支气管内装置。锚固件可以由支撑结构的周边部分或支撑结构的中心部分承载。阻塞构件可以是单向阀。

70. 发明申请

US20130184519A1 CARDIAC SUPPORT DEVICE WITH DIFFERENTIAL COMPLIANCE 审中-公开
标题翻译： CARDIAC支持设备与差异合规
公开(公告)号：US20130184519A1
公开(公告)日：2013-07-18
申请号：US13625727
申请日：2012-09-24
申请人： Clifton A. Alferness , Jai Shankar Raman , John Melmouth Power
发明人： Clifton A. Alferness , Jai Shankar Raman , John Melmouth Power
IPC分类号： A61F2/24
CPC分类号： A61F2/2481 , A61F2002/0068
摘要： A cardiac support device comprising a jacket of flexible and biocompatible material having a first axis for alignment generally parallel to a longitudinal axis of a patient's heart and a second axis that is transverse to the first axis. The material exhibits an amount of expansion in response to a force applied to the material along the first axis that is different than an amount of expansion in response to the force applied to the material along the second axis.
摘要翻译：一种心脏支持装置，其包括柔性和生物相容性材料的护套，其具有大致平行于患者心脏的纵向轴线的对准的第一轴线和横向于第一轴线的第二轴线。该材料响应于沿着第一轴施加到材料上的力而响应于沿着沿着第二轴施加到材料的力而产生的膨胀量不同的膨胀量。

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