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61. 发明申请

US20100305608A1 AUTOLOGOUS WOUND SEALING APPARATUS 有权
标题翻译：自动封口机
公开(公告)号：US20100305608A1
公开(公告)日：2010-12-02
申请号：US12853139
申请日：2010-08-09
申请人： Kenneth J. Michlitsch
发明人： Kenneth J. Michlitsch
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B17/00491 , A61B2017/00637 , A61B2017/00654 , A61B2017/00659 , A61B2017/00672
摘要： The apparatus is provided for sealing a vascular puncture tract by forming the autologous plug within the puncture tract, and extruding that plug into the puncture tract. The apparatus of the present invention forms an autologous blood plug by drawing blood into the apparatus from a vessel, mixing a blood congealing agent with the drawn blood, and ejecting a plug formed from the clotted blood within the puncture tract. Also provided are various closure elements to isolate the drawn blood from the vessel during mixture with the blood congealing agent, and to facilitate placement of the apparatus relative to the vessel.
摘要翻译：该装置用于通过在穿刺管内形成自体塞子并将该塞子挤压到穿刺管中来密封血管穿刺道。本发明的装置通过从血管中将血液吸入装置，将血液凝固剂与抽取的血液混合，并在穿刺管内喷出由凝血血液形成的塞子，形成自体血栓。还提供了各种封闭元件，以在与血液凝结剂混合期间将抽取的血液与血管隔离，并且便于相对于血管的装置放置。

62. 发明申请

US20100137860A1 APPARATUS FOR PERFORMING A NON-CONTINUOUS CIRCUMFERENTIAL TREATMENT OF A BODY LUMEN 有权
标题翻译：用于实施身体不连续的循环治疗的装置
公开(公告)号：US20100137860A1
公开(公告)日：2010-06-03
申请号：US12539390
申请日：2009-08-11
申请人： Denise Demarais , Hanson Gifford, III , Mark Deem , Nicolas Zadno , Benjamin J. Clark , Andrew Wu , Kenneth J. Michlitsch
发明人： Denise Demarais , Hanson Gifford, III , Mark Deem , Nicolas Zadno , Benjamin J. Clark , Andrew Wu , Kenneth J. Michlitsch
IPC分类号： A61B18/18 , A61M29/00
CPC分类号： A61B18/1492 , A61B18/1206 , A61B18/18 , A61B2018/00023 , A61B2018/00077 , A61B2018/0016 , A61B2018/0022 , A61B2018/00267 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00648 , A61B2018/00791 , A61B2018/00875 , A61B2018/124 , A61B2018/1435 , A61B2018/1465 , A61N1/0551 , A61N1/32 , A61N1/327 , A61N1/36007 , A61N7/022
摘要： Methods and apparatus are provided for non-continuous circumferential treatment of a body lumen. Apparatus may be positioned within a body lumen of a patient and may deliver energy at a first lengthwise and angular position to create a less-than-full circumferential treatment zone at the first position. The apparatus also may deliver energy at one or more additional lengthwise and angular positions within the body lumen to create less-than-full circumferential treatment zone(s) at the one or more additional positions that are offset lengthwise and angularly from the first treatment zone. Superimposition of the first treatment zone and the one or more additional treatment zones defines a non-continuous circumferential treatment zone without formation of a continuous circumferential lesion. Various embodiments of methods and apparatus for achieving such non-continuous circumferential treatment are provided.
摘要翻译：提供了用于不间断地周围处理体腔的方法和装置。装置可以定位在患者的体腔内，并且可以在第一纵向和角位置处递送能量，以在第一位置处产生小于整个圆周的处理区域。该装置还可以在体腔内的一个或多个附加的纵向和角度位置处递送能量，以在一个或多个附加位置处创建小于整个圆周处理区域，该一个或多个附加位置从第一处理区域纵向和角度偏移。第一处理区和一个或多个另外的处理区的叠置限定非连续的圆周处理区而不形成连续的周向损伤。提供了用于实现这种非连续圆周处理的方法和装置的各种实施例。

63. 发明授权

US07704264B2 Apparatus and methods for forming and securing gastrointestinal tissue folds 有权
标题翻译：用于形成和固定胃肠组织褶皱的装置和方法
公开(公告)号：US07704264B2
公开(公告)日：2010-04-27
申请号：US10992306
申请日：2004-11-17
申请人： Richard C. Ewers , Vahid C. Saadat , Kenneth J. Michlitsch , Chris Rothe , Rodney Brenneman , Cang C. Lam , Eugene C. Chen
发明人： Richard C. Ewers , Vahid C. Saadat , Kenneth J. Michlitsch , Chris Rothe , Rodney Brenneman , Cang C. Lam , Eugene C. Chen
IPC分类号： A61B17/10 , A61B17/08 , A61B17/15 , A61B17/128
CPC分类号： A61B1/0055 , A61B1/00135 , A61B1/018 , A61B1/2736 , A61B1/31 , A61B17/00234 , A61B17/0218 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/062 , A61B17/0625 , A61B17/0644 , A61B17/29 , A61B17/295 , A61B17/3421 , A61B17/3468 , A61B17/3478 , A61B2017/00269 , A61B2017/003 , A61B2017/00353 , A61B2017/00827 , A61B2017/0404 , A61B2017/0417 , A61B2017/0419 , A61B2017/0443 , A61B2017/0451 , A61B2017/0454 , A61B2017/0458 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/061 , A61B2017/06176 , A61B2017/0649 , A61B2017/2905 , A61B2017/2927 , A61B2017/2943 , A61B2017/3445 , A61B2017/3488 , A61B2090/3614 , A61F5/0086
摘要： Apparatus and methods are provided for forming a gastrointestinal tissue fold by engaging tissue at a first tissue contact point and moving the first tissue contact point from a position initially distal to, or in line with, a second tissue contact point to a position proximal of the second contact point, thereby forming the tissue fold, and extending an anchor assembly through the tissue fold from a vicinity of the second tissue contact point. Adjustable anchor assemblies; as well as anchor delivery systems, shape-lockable guides and methods for endoluminally performing medical procedures, such as gastric reduction, treatment of gastroesophageal reflux disease, resection of lesions, and treatment of bleeding sites; are also provided.
摘要翻译：提供了设备和方法，用于通过在第一组织接触点处接合组织并使第一组织接触点从最初远端或与第二组织接触点一致的位置移动到位于第二组织接触点附近的位置来形成胃肠组织折叠第二接触点，从而形成组织折叠，并且从第二组织接触点的附近延伸锚固组件穿过组织折叠。可调锚固组件; 以及锚定递送系统，可锁定形状的导管和用于内窥镜执行医学程序的方法，例如胃减压，治疗胃食管反流疾病，切除病变和治疗出血部位; 也提供。

64. 发明申请

US20090264997A1 Everting Heart Valve 有权
标题翻译：永恒心脏瓣膜
公开(公告)号：US20090264997A1
公开(公告)日：2009-10-22
申请号：US12492512
申请日：2009-06-26
申请人： Amr Salahieh , Ulrich R. Haug , Hans F. Valencia , Robert A. Geshlider , Tom Saul , Dwight P. Morejohn , Kenneth J. Michlitsch
发明人： Amr Salahieh , Ulrich R. Haug , Hans F. Valencia , Robert A. Geshlider , Tom Saul , Dwight P. Morejohn , Kenneth J. Michlitsch
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2220/0016 , A61F2220/0033 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2230/0065 , A61F2230/0078
摘要： The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve. In some embodiments, the replacement valve is adapted to wrap about the anchor, for example, by everting during endovascular deployment. In some embodiments, the replacement valve is not connected to expandable portions of the anchor. In some embodiments, the anchor is configured for active foreshortening during endovascular deployment. In some embodiments, the anchor includes expandable lip and skirt regions for engaging the patient's heart valve during deployment. In some embodiments, the anchor comprises a braid fabricated from a single strand of wire. In some embodiments, the apparatus includes a lock configured to maintain anchor expansion. The invention also includes methods for endovascularly replacing a patient's heart valve. In some embodiments, the method includes the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve, wrapping at least a portion of the replacement valve about the anchor, and expanding the anchor to a deployed configuration.
摘要翻译：本发明提供了用于血管内替代患者心脏瓣膜的方法和装置。该装置包括置换瓣膜和可扩张锚固件，其可构造成用于血管内递送至患者心脏瓣膜附近。在一些实施例中，替换瓣膜适于例如在血管内部署过程中绕过锚固件。在一些实施例中，替换阀不连接到锚的可膨胀部分。在一些实施例中，锚定构件用于在血管内部署过程中进行主动缩短。在一些实施例中，锚固件包括用于在展开期间与患者的心脏瓣膜接合的可扩张唇缘和裙部区域。在一些实施例中，锚固件包括由单股线制成的编织物。在一些实施例中，该装置包括被配置成保持锚固扩展的锁。本发明还包括用于血管内替代患者心脏瓣膜的方法。在一些实施例中，该方法包括以下步骤：将置换瓣膜和可膨胀锚固件血管内输送到心脏瓣膜附近，将替代瓣膜的至少一部分围绕锚定件包裹，并将锚固件扩展至展开构造。

65. 发明授权

US07361180B2 Apparatus for manipulating and securing tissue 有权
标题翻译：用于操纵和固定组织的装置
公开(公告)号：US07361180B2
公开(公告)日：2008-04-22
申请号：US10954666
申请日：2004-09-29
申请人： Vahid Saadat , Richard C. Ewers , Cang C. Lam , Robert A. Vaughan , Chris Rothe , Kenneth J. Michlitsch
发明人： Vahid Saadat , Richard C. Ewers , Cang C. Lam , Robert A. Vaughan , Chris Rothe , Kenneth J. Michlitsch
IPC分类号： A61B17/00 , A61B17/10 , A61B17/08
CPC分类号： A61F5/0086 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0483 , A61B17/0487 , A61B17/06 , A61B17/06066 , A61B17/064 , A61B17/08 , A61B17/10 , A61B17/12013 , A61B17/1285 , A61B17/29 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0446 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0475 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/081 , A61B2017/3488
摘要： Apparatus for manipulating and securing tissue are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have an elongate tubular member, an engagement member slidably disposed through the tubular member and a distal end adapted to engage tissue via a helical member, tissue stabilizing members positioned at the tubular member distal end which are adapted to stabilize tissue therebetween, and a delivery tube pivotable about the tissue stabilizer. The stabilizing members can be adapted to become angled relative to a longitudinal axis of the elongate tubular member. Moreover, one or all the articulation controls and functions can be integrated into a singular handle assembly connectable to the tissue manipulation assembly via a rigid or flexible tubular body.
摘要翻译：本文描述了用于操纵和固定组织的装置。在组织折叠在患者体内产生时，组织操作组件通常可以具有细长的管状构件，可滑动地设置穿过管状构件的接合构件和适于通过螺旋构件接合组织的远端，组织稳定构件所述管状构件远端适于在其间稳定组织，以及可围绕所述组织稳定器枢转的输送管。稳定构件可以适于相对于细长管状构件的纵向轴线成角度。此外，一个或所有关节运动控制和功能可以集成到通过刚性或柔性管状体连接到组织操作组件的单个手柄组件中。

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