专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

61. 发明授权

US4026894A Antihypertensive agents 失效
标题翻译：抗高血压药
公开(公告)号：US4026894A
公开(公告)日：1977-05-31
申请号：US621980
申请日：1975-10-14
申请人： Martin Winn , Jaroslav Kyncl , Daniel Ambrose Dunnigan , Peter Hadley Jones
发明人： Martin Winn , Jaroslav Kyncl , Daniel Ambrose Dunnigan , Peter Hadley Jones
IPC分类号： C07D405/12 , A61K31/505 , A61P9/12 , A61P25/04 , C07D309/08 , C07D239/84
CPC分类号： C07D309/08
摘要： Described are antihypertensive agents selected from the class consisting of 2[4(tetrahydro-2-furoyl)-piperazino]-4-amino-6,7-dimethoxyquinazoline and 2-[4(tetrahydropyran-2-carbonyl)-piperazinyl]-4-amino-6,7-dimethoxyquinazoline, and pharmaceutically acceptable acid addition salts thereof. The compounds are highly water soluble and can be administered in time release form as well as parenterally, including intravenously.
摘要翻译：描述了选自2 [4（四氢-2-呋喃基） - 哌嗪基] -4-氨基-6,7-二甲氧基喹唑啉和2- [4（四氢吡喃-2-羰基） - 哌嗪基] -4的抗高血压药 - 氨基-6,7-二甲氧基喹唑啉及其药学上可接受的酸加成盐。这些化合物是高度水溶性的，并且可以以时间释放形式以及肠胃外给药，包括静脉内给药。

62. 再颁专利

USRE29196E Alkylphenyl benzopyranopyridines 失效
标题翻译：烷基苯基苯并吡喃并吡啶
公开(公告)号：USRE29196E
公开(公告)日：1977-04-26
申请号：US699831
申请日：1976-06-25
申请人： Martin Winn
发明人： Martin Winn
IPC分类号： C07C37/055 , C07C39/367 , C07C43/205 , C07D491/04
CPC分类号： C07D491/04 , C07C37/055 , C07C43/2055
摘要： Alkylphenyl benzopyranopyridines represented by the formula ##STR1## where R.sub.1 is hydrogen, loweralkyl, loweralkanoyl, cycloalkylloweralkyl, cycloalkylloweralkanoyl, loweralkenyl, loweralkynyl, haloloweralkenyl, phenylloweralkyl, phenylloweralkenyl or phenylloweralkynyl; R.sub.2 is loweralkyl; R.sub.3 is hydrogen; Y is a straight or branched chain alkylene group having from one to ten carbon atoms; and each R.sub.4 and R.sub.5 and R.sub.6 are the same or different members of the group consisting of hydrogen, halo, trifluoromethyl or loweralkyl; and the pharmaceutically acceptable salts thereof.

63. 发明授权

US3947462A 2,4,7-substituted 5-hydroxy benzopyrans and esters 失效
标题翻译： 2,4,7-取代的5-羟基苯并吡喃和酯
公开(公告)号：US3947462A
公开(公告)日：1976-03-30
申请号：US472243
申请日：1974-05-22
申请人： David Lloyd Arendsen , Martin Winn
发明人： David Lloyd Arendsen , Martin Winn
IPC分类号： C07C37/055 , C07D311/60
CPC分类号： C07C37/055 , Y10S514/96
摘要： 2,4,7-Substituted 5-hydroxy benzopyrans and dihydrobenzopyrans and their esters represented by the formulae ##SPC1##Wherein each R.sub.1 is loweralkyl, and R.sub.2 is hydrogen, loweralkanoyl or ##SPC2##With Y being a straight or branched chain alkylene group having from 1-8 carbon atoms; a is an integer from 1-4; b is an integer from 1-4; X is CH.sub.2, O, S, or NR.sub.5 with R.sub.5 being hydrogen or loweralkyl, with the limitation that when X is O, S, or NR.sub.5, the sum of a and b is 3 or 4 and R.sub.4 is hydrogen or loweralkyl; and R.sub.3 is ##SPC3##With Y' being a straight or branched chain alkylene group having from 1-10 carbon atoms; and each R.sub.7, R.sub.8 and R.sub.9 are the same or different members of the group consisting of hydrogen, halo, trifluoromethyl or loweralkyl and the pharmaceutically acceptable salts thereof.
摘要翻译： 2,4,7-取代的5-羟基苯并吡喃和二氢苯并吡喃及其由下式表示的酯其中R 1为低级烷基，R 2为氢，低级烷酰基或Y Y为具有1-8个碳原子的直链或支链亚烷基 ; a是1-4的整数; b是1-4的整数; X为CH 2，O，S或NR 5，其中R 5为氢或低级烷基，限制在X为O，S或NR 5时，a和b之和为3或4，R4为氢或低级烷基; 并且R 3为Y Y'为具有1-10个碳原子的直链或支链亚烷基; 并且每个R 7，R 8和R 9是由氢，卤素，三氟甲基或低级烷基组成的组的相同或不同的成员及其药学上可接受的盐。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式