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61. 发明授权

US06201005B1 Method for inhibiting lymphokine production 失效
标题翻译：抑制淋巴细胞生成的方法
公开(公告)号：US06201005B1
公开(公告)日：2001-03-13
申请号：US09411630
申请日：1999-10-01
申请人： Masakuni Okuhara , Hirokazu Tanaka , Toshio Goto , Tohru Kino , Hiroshi Hatanaka
发明人： Masakuni Okuhara , Hirokazu Tanaka , Toshio Goto , Tohru Kino , Hiroshi Hatanaka
IPC分类号： A01N4338
CPC分类号： C07D498/18 , C07H19/01 , C12P17/188 , C12P19/44 , C12R1/465 , C12R1/55 , Y02P20/55 , Y10S435/886 , Y10S435/898
摘要： This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: to a process for their production, to a pharmaceutical composition containing the same and to a use thereof.
摘要翻译：本发明涉及可用于治疗和预防移植抵抗力的三环化合物，通过髓质骨移植自身免疫性疾病，传染病等的移植物抗宿主病，其可以由下式表示：制备成含有该组合物的药物组合物及其用途。

62. 发明授权

US6129143A Brazing sheet having an excellent corrosion resistance for use in a heat exchanger, and a heat exchanger using the same 失效
标题翻译：在热交换器中使用具有优异的耐腐蚀性的钎焊片和使用其的热交换器
公开(公告)号：US6129143A
公开(公告)日：2000-10-10
申请号：US906455
申请日：1997-08-05
申请人： Yoshiharu Hasegawa , Haruhiko Miyachi , Yuji Suzuki , Hiroshi Ikeda , Hirokazu Tanaka , Takahiro Koyama , Koji Hirao
发明人： Yoshiharu Hasegawa , Haruhiko Miyachi , Yuji Suzuki , Hiroshi Ikeda , Hirokazu Tanaka , Takahiro Koyama , Koji Hirao
IPC分类号： B23K35/02 , B23K35/28 , B32B15/01 , F28F21/08 , B32B15/20
CPC分类号： B32B15/016 , B23K35/286 , F28F21/089 , B23K35/0238 , Y10S428/933 , Y10T428/12764
摘要： A brazing sheet which has an excellent corrosion resistance and cladding rolling property, and is formed from a four layer aluminum alloy cladding member, and a heat exchanger of aluminum alloy, in which the brazing sheet is used, are provided. The brazing sheet is suitable for use as a member in the fluid path of an aluminum heat exchange for a car, and particularly, as a core plate of a drawn cup type heat exchanger. In the brazing sheet, one side of a core member is cladded with an intermediate member less noble than a core member, and the other side of both the core member and the intermediate member are cladded with Al--Si--Mg type cladding member, wherein the core member is of an aluminum alloy containing 0.5 to 1.6% of Mn, 0.15 to 0.35% of Cu, 0.05 to 0.50% of Mg, 0.06 to 0.30% of Ti, and the remainder being Al and unavoidable impurities, and the intermediate member contains 0.5 to 1.2% of Mn and the remainder being aluminum and unavoidable impurities, and 0.05 to 1.2% of Mg, if desired, and has a 70 to 130% deformation resistance. The intermediate member may be composed of an aluminum alloy containing 1 to 5% of Zn, 0.5 to 1.2% of Mg, and the remainder being Al and unavoidable impurities.
摘要翻译：提供具有优异的耐腐蚀性和包层轧制性的钎焊板，由四层铝合金包覆部件和使用钎焊板的铝合金热交换器形成。钎焊片适合用作汽车铝热交换器的流体路径中的部件，特别是作为拉拔式热交换器的芯板。在钎焊片中，芯构件的一侧被覆有中心构件，其中心构件比芯构件的贵度低，并且芯构件和中间构件的另一侧被Al-Si-Mg型包覆构件包覆，其中芯构件是含有Mn：0.5〜1.6％，Cu：0.15〜0.35％，Mg：0.05〜0.50％，Ti：0.06〜0.30％，余量：Al和不可避免的杂质的铝合金，中间构件含有0.5〜1.2％的Mn，其余为铝和不可避免的杂质，如果需要，含有0.05〜1.2％的Mg，并且具有70〜130％的变形抗力。中间构件可以由含有1至5％的Zn，0.5至1.2％的Mg，其余为Al和不可避免的杂质的铝合金构成。

63. 发明授权

US5888972A Peptide compounds, their preparation and uses 失效
标题翻译：肽化合物，其制备和用途
公开(公告)号：US5888972A
公开(公告)日：1999-03-30
申请号：US564271
申请日：1997-06-24
申请人： Keiji Hemmi, deceased , Masahiro Neya , Naoki Fukami , Natsuko Kayakiri , Hirokazu Tanaka
发明人： Keiji Hemmi, deceased , Masahiro Neya , Naoki Fukami , Natsuko Kayakiri , Hirokazu Tanaka
IPC分类号： A61K38/00 , A61P9/12 , C07K5/02 , C07K5/03 , C07K5/062 , C07K5/08 , C07K5/083 , A61K38/06 , A61K38/07
CPC分类号： C07K5/0808 , C07K5/0207 , C07K5/0827 , A61K38/00 , Y02P20/55
摘要： A compound of the formula: ##STR1## in which R.sup.4 is acyl,R.sup.5 is lower alkyl,R.sup.6 is optionally substituted ar(lower)alkyl or optionally substituted heterocyclic-(lower)alkyl,R.sup.7 is lower alkyl or lower alkylthio(lower)alkyl,R.sup.8 is carboxy or protected carboxy,A is lower alkylene,Z is a group of the formula: ##STR2## wherein R.sup.1 is hydrogen, lower alkyl, common amino-protective group or optionally substituted ar(lower)alkyl,R.sup.2 is hydrogen, lower alkyl, optionally substituted ar(lower)alkyl, optionally substituted heterocyclic-(lower)alkyl, optionally substituted cyclo(lower)alkyl(lower)alkyl, common amino-protective group, amino(or protected amino)(lower)alkyl, optionally substituted heterocyclic-carbonyl or cyclo(lower)alkyl, andR.sup.3 is optionally substituted heterocyclic(lower)alkyl, andm is an integer of 0 to 2,or pharmaceutically acceptable salts thereof, useful as endothelin antagonist.
摘要翻译： PCT No.PCT / JP94 / 01042 Sec。 371日期1996年6月24日 102（e）1996年6月24日PCT 1994年6月28日PCT公布。公开号WO95 / 00537 日期1995年1月5日具有下式的化合物：其中R 4为酰基，R 5为低级烷基，R 6为任选取代的芳（低级）烷基或任选取代的杂环 - （低级）烷基，R 7为低级烷基或低级烷硫基（低级）烷基，R 8为羧基或被保护的羧基，A为低级亚烷基，Z为下式基团：其中R 1为氢，低级烷基，普通氨基保护基或任选取代的芳（低级）烷基（低级）烷基，任选取代的杂环 - （低级）烷基，任选取代的环（低级）烷基（低级）烷基，常用氨基保护基，氨基（或被保护的氨基）（低级烷基，任选取代的杂环羰基或环（低级）烷基，R 3为任选取代的杂环（低级）烷基，m为0-2的整数，或其药学上可接受的盐，可用作内皮素拮抗剂。

64. 发明授权

US5861771A Regulator circuit and semiconductor integrated circuit device having the same 失效
标题翻译：调节器电路和具有其的半导体集成电路器件
公开(公告)号：US5861771A
公开(公告)日：1999-01-19
申请号：US871954
申请日：1997-06-10
申请人： Atsushi Matsuda , Hirokazu Tanaka , Kunihiko Gotoh
发明人： Atsushi Matsuda , Hirokazu Tanaka , Kunihiko Gotoh
IPC分类号： G05F1/56 , G05F1/46 , G11C11/407 , H02M3/156 , G05F3/16
CPC分类号： H02M3/1563 , G05F1/465
摘要： A regulator circuit includes an output circuit outputting an output voltage based on a control voltage, a reference voltage generating circuit generating a reference voltage, an output voltage control circuit comparing the reference voltage with a voltage depending on the output voltage and producing the control voltage based on a comparison result, and a power supply circuit which supplies the reference voltage generating circuit and the output voltage control circuit with a first power supply voltage which is different from a second power supply voltage supplied to the output circuit.
摘要翻译：调节器电路包括输出基于控制电压的输出电压的输出电路，产生参考电压的参考电压产生电路，将参考电压与取决于输出电压的电压进行比较并输出基于控制电压的输出电压控制电路以及电源电路，其向基准电压产生电路和输出电压控制电路提供与提供给输出电路的第二电源电压不同的第一电源电压。

65. 发明授权

US5663673A Output circuit having at least one external transistor 失效
标题翻译：输出电路具有至少一个外部晶体管
公开(公告)号：US5663673A
公开(公告)日：1997-09-02
申请号：US413947
申请日：1995-03-30
申请人： Hirokazu Tanaka , Tatsuo Kumano , Tetsuji Funaki , Takahiro Watai
发明人： Hirokazu Tanaka , Tatsuo Kumano , Tetsuji Funaki , Takahiro Watai
IPC分类号： H03G5/16 , H03F1/30 , H03F3/30 , H03F3/45 , H04M19/00 , H03F3/26 , H03K17/16
CPC分类号： H03F3/3071 , H03F1/307
摘要： An output circuit, for minimizing output idle current fluctuations and improve the output voltage range, has first and second transistors connected to first and second power sources, with a plurality of diodes connected to control terminals of the first and second transistors. The output circuit further includes a third transistor having a first terminal connected to the second power source and a second terminal connected to a predetermined position among the plurality of diodes. A predetermined voltage is applied from the diodes to the control terminal of the first transistor when the third transistor is saturated, to bring a level of an output of said output circuit close to a level of the second power source. A fourth transistor, a fifth transistor, a first resistor, and a capacitor are also provided. The forth transistor has a control terminal connected to an output of a differential circuit, and a first terminal connected to the second power source through the first resistor as well as to the control terminals of the third and fifth transistors. A second terminal is connected to the first power source, with the fifth transistor having a first terminal connected to the second power source and a second terminal connected to the control terminal of the second transistor. The capacitor is connected between the control terminal of the fourth transistor and the second terminal of the fifth transistor. This output circuit also limits the output voltage without changing the impedance of the high-impedance input.
摘要翻译：用于最小化输出空闲电流波动并改善输出电压范围的输出电路具有连接到第一和第二电源的第一和第二晶体管，多个二极管连接到第一和第二晶体管的控制端子。输出电路还包括具有连接到第二电源的第一端子和连接到多个二极管中的预定位置的第二端子的第三晶体管。当第三晶体管饱和时，从二极管向第一晶体管的控制端施加预定电压，以使所述输出电路的输出电平接近第二电源的电平。还提供第四晶体管，第五晶体管，第一电阻器和电容器。第四晶体管具有连接到差分电路的输出的控制端子，以及通过第一电阻器连接到第二电源的第一端子以及第三和第五晶体管的控制端子。第二端子连接到第一电源，第五晶体管具有连接到第二电源的第一端子和连接到第二晶体管的控制端子的第二端子。电容器连接在第四晶体管的控制端和第五晶体管的第二端之间。该输出电路还限制输出电压，而不改变高阻抗输入的阻抗。

66. 发明授权

US5624842A Strain of Streptomyces for the production of tricyclo compounds 失效
标题翻译：用于生产三环化合物的链霉菌菌株
公开(公告)号：US5624842A
公开(公告)日：1997-04-29
申请号：US450412
申请日：1995-05-25
申请人： Masakuni Okuhara , Hirokazu Tanaka , Toshio Goto , Tohru Kino , Hiroshi Hatanaka
发明人： Masakuni Okuhara , Hirokazu Tanaka , Toshio Goto , Tohru Kino , Hiroshi Hatanaka
IPC分类号： A01N43/38 , A61K31/00 , A61K31/33 , A61K31/40 , A61K31/407 , A61K31/435 , A61K31/4353 , A61K31/436 , A61K31/445 , A61K31/4465 , A61K31/4523 , A61K31/453 , A61K31/4745 , A61P31/00 , A61P31/04 , A61P37/00 , A61P37/06 , C07D491/14 , C07D498/04 , C07D498/14 , C07D498/18 , C07D519/00 , C07H19/01 , C12N1/20 , C12P17/16 , C12P17/18 , C12P19/44 , C12R1/465 , C12R1/55
CPC分类号： C07D498/18 , C07H19/01 , C12P17/188 , C12P19/44 , C12R1/465 , C12R1/55 , Y02P20/55 , Y10S435/886 , Y10S435/898
摘要： This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: ##STR1## to a process for their production, to a pharmaceutical composition containing the same and to a use thereof.
摘要翻译：本发明涉及可用于治疗和预防移植抵抗的三环类化合物，通过髓质移植移植物抗宿主病，自身免疫性疾病，感染性疾病等，其可以由下式表示：（ I）涉及其制备方法，含有该方法的药物组合物及其用途。

67. 发明授权

US5600492A Surface-curved optical element adapted for emergence and incidence of parallel light rays 失效
标题翻译：适用于平行光线的出射和入射的曲面光学元件
公开(公告)号：US5600492A
公开(公告)日：1997-02-04
申请号：US418974
申请日：1995-04-07
申请人： Hirokazu Tanaka , Fumio Ogawa
发明人： Hirokazu Tanaka , Fumio Ogawa
IPC分类号： G02B5/00 , G02B3/02 , G02B13/18
CPC分类号： G02B3/04 , G02B5/00 , H04B10/11
摘要： The invention relates to an optical element being conveniently useful, for example as an external cover of transmitter and/or receiver for optical communication and more particularly to a surface-curved optical element comprising a transparent body of a refractive index n having a pair of boundary surfaces defined in their cross-section by the corresponding pair of ellipsoidal curves of an eccentricity 1/n. The boundary surfaces of this surface-curved optical element are configured so that they should have their focal points aligned with one another on a straight line and their focal points which are remote from vertices of the respective ellipsoidal surfaces corresponding to the apsides of the respective ellipsoidal curves should be coincident with each other, whereby parallel light rays entering the surface-curved optical element should emerge from this in the form of the parallel light rays without any disturbance.
摘要翻译：本发明涉及一种光学元件，其便于使用，例如作为用于光学通信的发射器和/或接收器的外部盖，更具体地涉及一种表面弯曲光学元件，其包括具有一对边界的折射率n的透明体在它们的横截面中由对应的偏心率1 / n的椭圆曲线对限定的表面。该曲面光学元件的边界面被配置为使得它们的焦点在直线上彼此对准，并且它们的焦点远离相应于椭圆体的侧面的各个椭圆面的顶点曲线应该彼此一致，由此进入表面曲线光学元件的平行光线将以平行光线的形式从其中出现而没有任何干扰。

68. 发明授权

US5585893A Image forming apparatus 失效
标题翻译：图像形成装置
公开(公告)号：US5585893A
公开(公告)日：1996-12-17
申请号：US433860
申请日：1995-05-02
申请人： Hirokazu Fujita , Yoshinobu Okumura , Hirokazu Tanaka
发明人： Hirokazu Fujita , Yoshinobu Okumura , Hirokazu Tanaka
IPC分类号： G03G15/05 , G03G15/34 , G03G21/00 , G03G21/10 , G03G21/16 , G03G21/18 , G03G15/00
CPC分类号： G03G21/1821 , G03G15/04054 , G03G15/04081 , G03G15/344 , G03G2215/0497 , G03G2217/0091 , G03G2221/1606 , G03G2221/1636
摘要： An image forming apparatus in accordance with the present invention is provided with a unit composed of members such as a photoreceptor drum and an optical system, the unit being attachably and detachably provided with respect to the image forming apparatus main body. With the arrangement, the replacement of the photoreceptor drum can be made at the user's end with ease. It is not necessary to carry out fine adjustments at the user's end for positioning the photoreceptor drum and optical system with respect to the image forming apparatus main body. Thus, professional skill is not required for the replacement of the photoreceptor drum, thereby resulting in that the operations such as maintenance can be effectively made. It is preferable that a cleaner is further provided for removing any contaminated materials adhering to the inner surface of the photoreceptor drum. With the cleaner, the contaminated materials can be removed from the inner surface of the photoreceptor drum, thereby avoiding that the exposure of the photoreceptor drum is not appropriately carried out.
摘要翻译：根据本发明的图像形成装置设置有由诸如感光鼓和光学系统的部件组成的单元，该单元可相对于图像形成装置主体可拆卸地设置。通过这种布置，可以容易地在用户端进行感光鼓的更换。在用户端不需要进行微调，以便相对于图像形成装置主体定位感光鼓和光学系统。因此，为了更换感光鼓不需要专业技术，从而可以有效地进行诸如维护的操作。优选的是，进一步设置用于除去粘附在感光鼓的内表面上的任何污染物质的清洁器。利用清洁器，可以从感光鼓的内表面去除受污染的材料，从而避免感光鼓的曝光不适当地进行。

69. 发明授权

US5572300A Developing device containing for storing developer having zoner and carrier 失效
标题翻译：开发设备，用于存储具有分区和载体的开发者
公开(公告)号：US5572300A
公开(公告)日：1996-11-05
申请号：US208431
申请日：1994-03-09
申请人： Hideo Yamasa , Yasuhiro Takai , Atsushi Ueda , Hirokazu Tanaka
发明人： Hideo Yamasa , Yasuhiro Takai , Atsushi Ueda , Hirokazu Tanaka
IPC分类号： G03G15/08 , G03G21/10
CPC分类号： G03G15/0844 , G03G15/0822 , G03G2215/0822
摘要： The present invention provides in a preferred embodiment a developer container having a supply and discharge shaft which is driven and rotated in a direction by a supply and discharge shaft motor, a supply screw mounted on one of the ends of the supply and discharge shaft for bringing unused developer in a developer supply container into a developer container, and a discharge screw mounted on the other end of the supply and discharge shaft for discharging the developer in the developer container through a developer discharge opening. With this structure, the ratio of replacing old developer with new developer in the developer container is controlled in the desired manner, and the charging property of the developer is maintained substantially uniform. Additionally, since the replacement efficiency of the developer is improved, the consumption of the developer is reduced. Moreover, even when a copying machine is tilted, a large amount of developer is unlikely to be discharged.
摘要翻译：本发明在优选实施例中提供了一种显影剂容器，该容器具有一供给排出轴，该排放轴由一供给排出轴电动机驱动并沿一方向旋转;供给螺钉，其安装在供排排轴的一端上，显影剂供应容器中的未使用的显影剂进入显影剂容器，以及安装在供排排轴的另一端的排出螺杆，用于通过显影剂排出口排出显影剂容器中的显影剂。利用这种结构，以期望的方式控制在显影剂容器中更换旧显影剂与新显影剂的比例，并且显影剂的带电性能保持基本均匀。此外，由于显影剂的替换效率提高，因此显影剂的消耗降低。此外，即使当复印机倾斜时，大量的显影剂也不太可能被排出。

70. 发明授权

US5496727A Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same 失效
公开(公告)号：US5496727A
公开(公告)日：1996-03-05
申请号：US450639
申请日：1995-05-25
申请人： Masakuni Okuhara , Hirokazu Tanaka , Toshio Goto , Tohru Kino , Hiroshi Hatanaka
发明人： Masakuni Okuhara , Hirokazu Tanaka , Toshio Goto , Tohru Kino , Hiroshi Hatanaka
IPC分类号： A01N43/38 , A61K31/00 , A61K31/33 , A61K31/40 , A61K31/407 , A61K31/435 , A61K31/4353 , A61K31/436 , A61K31/445 , A61K31/4465 , A61K31/4523 , A61K31/453 , A61K31/4745 , A61P31/00 , A61P31/04 , A61P37/00 , A61P37/06 , C07D491/14 , C07D498/04 , C07D498/14 , C07D498/18 , C07D519/00 , C07H19/01 , C12N1/20 , C12P17/16 , C12P17/18 , C12P19/44 , C12R1/465 , C12R1/55
CPC分类号： C07D498/18 , C07H19/01 , C12P17/188 , C12P19/44 , C12R1/465 , C12R1/55 , Y02P20/55 , Y10S435/886 , Y10S435/898
摘要： This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: ##STR1## to a process for their production, to a pharmaceutical composition containing the same and to a use thereof.

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