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61. 发明授权

US06578947B1 Ink drying prevention apparatus, ink-jet recording head storage container, ink-jet recording apparatus and ink drying prevention method 失效
标题翻译：油墨干燥防止装置，喷墨记录头存储容器，喷墨记录装置和油墨干燥防止方法
公开(公告)号：US06578947B1
公开(公告)日：2003-06-17
申请号：US09721691
申请日：2000-11-27
申请人： Yasufumi Suwabe , Susumu Hirakata , Satoshi Mohri , Yuji Suemitsu , Hiroaki Satoh
发明人： Yasufumi Suwabe , Susumu Hirakata , Satoshi Mohri , Yuji Suemitsu , Hiroaki Satoh
IPC分类号： B41J2165
CPC分类号： B41J2/16508 , B41J2002/16502
摘要： The present invention provides an ink drying prevention apparatus that can prevent ink within an ink-jet recording head from drying, for a long period of time. The ink drying prevention apparatus prevents ink within an ink-jet recording head from drying, and includes a porous substance permeated with a seal liquid that is nonvolatile and incompatible with the ink within the head, wherein the porous substance can contact a nozzle surface of the ink-jet recording head. The seal liquid forms plural meniscuses in an interface with the nozzle surface and inside the porous substance to block air paths, thereby preventing ink within a nozzle exposed to the nozzle surface from drying.
摘要翻译：本发明提供一种能够防止喷墨记录头内的墨水长时间干燥的防墨装置。墨水干燥防止装置防止喷墨记录头内的墨水干燥，并且包括渗透有非挥发性且与头部内的墨水不相容的密封液体的多孔物质，其中多孔物质可以接触喷墨记录头的喷嘴表面喷墨记录头。密封液体在与喷嘴表面和多孔物质内部的界面中形成多个弯液面以阻挡空气路径，从而防止暴露于喷嘴表面的喷嘴内的油墨干燥。

62. 发明授权

US06283579B1 Recording head 失效
标题翻译：录音头
公开(公告)号：US06283579B1
公开(公告)日：2001-09-04
申请号：US09099782
申请日：1998-06-19
申请人： Koichi Haga , Hiroaki Satoh , Ichirou Asai , Jiro Minabe
发明人： Koichi Haga , Hiroaki Satoh , Ichirou Asai , Jiro Minabe
IPC分类号： B41J2135
CPC分类号： B41J2/04 , B41J2002/14322
摘要： A recording head for carrying out printing by jetting ink drops for deposition at predetermined positions on recording media, and allowing minute drops to be jetted without using a nozzle to record high-definition images. The recording head includes an elastic member vibrating in response to the excitation of a vibration generating means vibrating in accordance with a pixel signal, wherein capillary waves are generated on the surface of ink by the vibration of the elastic member to jet the ink for deposition on recording media. The elastic member is of a cantilever construction that bending vibration is made by excitation. Also, the elastic member has a length of about 2&lgr; as the width of a side perpendicular to a vibration direction of bending vibration in the neighborhood of the tip of a free end of a cantilever construction, where &lgr; is given by the following expression: &lgr;={8&pgr;&sgr;/(&rgr;fe2)}⅓×104 (&mgr;m), where &sgr; is an ink surface tension (mN/m), &rgr; is an ink density (g/cm3), and fe is an excitation frequency (Hz).
摘要翻译：一种用于通过喷射墨滴进行打印的记录头，用于在记录介质上的预定位置沉积，并且允许在不使用喷嘴的情况下喷射微滴以记录高清晰图像。记录头包括响应于根据像素信号振动的振动产生装置的激发而振动的弹性构件，其中通过弹性构件的振动在墨表面上产生毛细波，以喷射用于沉积的墨录音媒体弹性构件是通过激励进行弯曲振动的悬臂结构。此外，弹性构件的长度为垂直于悬臂结构的自由端的尖端附近的弯曲振动的振动方向的一侧的宽度的长度，其中通过以下表达式给出lambd：lambd = {8pisigma /（rhofe2）} 1/3×104（mum），其中sigma是油墨表面张力（mN / m），rho是油墨密度（g / cm 3），fe是激发频率（Hz）。

63. 发明授权

US6046201A Pyridinecarboxamide derivatives 失效
标题翻译：吡啶甲酰胺衍生物
公开(公告)号：US6046201A
公开(公告)日：2000-04-04
申请号：US101441
申请日：1998-07-15
申请人： Norio Oshida , Yoji Mimaki , Hiroaki Satoh , Shinji Yokoyama , Yukiko Muraki , Kazumi Nishimura , Tamiko Hamada , Einosuke Sakurai , Hiroshi Sakai , Toshiji Sugai , Tomomi Tonoike , Koichi Itoh
发明人： Norio Oshida , Yoji Mimaki , Hiroaki Satoh , Shinji Yokoyama , Yukiko Muraki , Kazumi Nishimura , Tamiko Hamada , Einosuke Sakurai , Hiroshi Sakai , Toshiji Sugai , Tomomi Tonoike , Koichi Itoh
IPC分类号： C07D213/80 , C07D213/82 , A61K31/495 , C07D401/04
CPC分类号： C07D213/80 , C07D213/82
摘要： N-(12-Nitroxydodecyl)-6-(4-ethyl or isopropyl-1-piperazinyl)pyridine-3-carboxamide or physiologically acceptable salts thereof. The said compounds have excellent inhibiting activity of cerebral edema, especially ischemic cerebral edema, and inhibiting activity of delayed neuronal death (an inhibiting activity of Ca-influx in neuronal cells). Cerebral edema is a pathologic condition accompanying cerebrovascular disorders, especially the acute stage cerebrovascular disorders and then the compounds are useful as an inhibiting agent for cerebral edema or a therapeutic agent for cerebrovascular disorders. Moreover, because the compounds do hardly show a behavior suppressing action, which is considered to be side effect in treating cerebrovascular disorders at the acute stage, they are an excellent therapeutic agent for, in particular, the acute stage cerebrovascular disorders. Moreover, the compounds show a cerebral protective activity (an anti-anoxic activity), an activity of increasing cerebral blood flow, and an activity of inhibiting lipid peroxidation, and these activities may lead to the increased utility as a therapeutic agent for cerebrovascular disorders.
摘要翻译： PCT No.PCT / JP97 / 04208 Sec。 371日期：1998年7月15日 102（e）日期1998年7月15日PCT 1997年11月19日PCT PCT。出版物WO98 / 22440 日期1998年5月28日N-（12-硝基十二烷基）-6-（4-乙基或异丙基-1-哌嗪基）吡啶-3-甲酰胺或其生理上可接受的盐。所述化合物具有优异的脑水肿抑制活性，特别是缺血性脑水肿，抑制延迟性神经元死亡的活性（神经细胞内Ca流入的抑制活性）。脑水肿是伴随脑血管障碍，特别是急性期脑血管障碍的病理状况，然后该化合物可用作脑水肿的抑制剂或脑血管障碍的治疗剂。此外，由于化合物几乎不表现出在急性期治疗脑血管障碍中被认为是副作用的行为抑制作用，所以它们是特别是急性期脑血管障碍的优良治疗剂。此外，化合物显示脑保护活性（抗缺氧活性），增加脑血流量的活性和抑制脂质过氧化的活性，并且这些活性可导致作为脑血管障碍治疗剂的效用增加。

64. 发明授权

US5972943A Pyridinecarboxamide derivatives 失效
标题翻译：吡啶甲酰胺衍生物
公开(公告)号：US5972943A
公开(公告)日：1999-10-26
申请号：US101760
申请日：1998-07-20
申请人： Norio Oshida , Yoji Mimaki , Hiroaki Satoh , Shinji Yokoyama , Yukiko Muraki , Kazumi Nishimura , Tamiko Hamada , Einosuke Sakurai , Hiroshi Sakai , Toshiji Sugai , Tomomi Tonoike , Koichi Itoh
发明人： Norio Oshida , Yoji Mimaki , Hiroaki Satoh , Shinji Yokoyama , Yukiko Muraki , Kazumi Nishimura , Tamiko Hamada , Einosuke Sakurai , Hiroshi Sakai , Toshiji Sugai , Tomomi Tonoike , Koichi Itoh
IPC分类号： C07D213/80 , C07D213/82 , A61K31/495 , C07D401/04
CPC分类号： C07D213/80 , C07D213/82
摘要： Pyridinecarboxamide derivatives of the formula ##STR1## (wherein n represents an integer of 14-18, and R represents a hydrogen atom or a straight or branched C.sub.1 -C.sub.4 alkyl group) or physiologically acceptable salts thereof. The compounds have excellent inhibiting activity of cerebral edema, especially ischemic cerebral edema, and inhibiting activity of delayed death of neuronal cells (an inhibiting activity of Ca-influx in neuronal cells). Cerebral edema is a pathologic condition accompanying cerebrovascular disorders, especially the acute stage of cerebrovascular disorders and then the compounds are useful as an agent for inhibiting cerebral edema or a therapeutic agent for cerebrovascular disorders. Moreover, the compounds have no hypotensive action which is considered to be side-effect in treating the acute stage cerebrovascular disorders and hardly show a behavior suppressing action so that they are an excellent therapeutic agent for, in particular, the acute stage cerebrovascular disorders. Moreover, the compounds show a cerebral protective activity (an anti-anoxic activity), an increasing activity of cerebral blood flow, and an inhibiting activity of lipid peroxidation and these activities may lead to the increased utility as a therapeutic agent for cerebrovascular disorders.
摘要翻译： PCT No.PCT / JP97 / 04207 Sec。 371日期：1998年7月20日 102（e）1998年7月20日PCT PCT 1997年11月19日PCT公布。出版物WO98 / 22439 日期：1998年5月28日下式的吡啶甲酰胺衍生物（其中n表示14-18的整数，R表示氢原子或直链或支链的C 1 -C 4烷基）或其生理学上可接受的盐。该化合物具有优异的脑水肿抑制活性，特别是缺血性脑水肿，抑制神经元细胞延迟死亡的活性（神经细胞内Ca流入的抑制活性）。脑水肿是伴随脑血管障碍，特别是脑血管障碍的急性期的病理状况，然后该化合物可用作抑制脑水肿的药剂或脑血管障碍治疗剂。此外，化合物没有降压作用，被认为在治疗急性期脑血管障碍中具有副作用，并且几乎不显示行为抑制作用，因此它们是特别是急性期脑血管障碍的优良治疗剂。此外，化合物显示脑保护活性（抗缺氧活性），脑血流量的增加的活性和脂质过氧化的抑制活性，并且这些活性可能导致作为脑血管障碍治疗剂的效用增加。

65. 发明授权

US4877797A 1,4-Dihydropyridine derivatives and pharmaceutical compositions containing same 失效
标题翻译： 1,4-二氢吡啶衍生物和含有它们的药物组合物
公开(公告)号：US4877797A
公开(公告)日：1989-10-31
申请号：US67719
申请日：1987-06-15
申请人： Hiroaki Satoh , Hiroyasu Koyama , Yoshikuni Suzuki , Toshiji Sugai , Koichi Watanabe
发明人： Hiroaki Satoh , Hiroyasu Koyama , Yoshikuni Suzuki , Toshiji Sugai , Koichi Watanabe
IPC分类号： A61K31/4427 , A61K31/455 , A61K31/47 , A61P3/00 , A61P9/08 , A61P9/12 , C07D211/90 , C07D401/12
CPC分类号： C07D401/12 , C07D211/90
摘要： Compounds are described of the formula ##STR1## wherein R.sub.1 is a nitro or trifluoromethyl group; R.sub.2 is a C.sub.1 -C.sub.6 alkyl group; R.sub.3 is a pyridyl or pyridyl N-oxide group which may be substituted with halogen, hydroxyl, haloalkyl, C.sub.1 -C.sub.6 alkoxy or C.sub.1 -C.sub.6 alkyl and further may be fused with a benzene or naphthalene ring, said ring being optionally substituted with C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkoxy, halogen or haloalkyl, and a pharmaceutically acceptable acid addition salt thereof. The compounds of the formula (I) are of vasodilating and blood pressure lowering activities and thus may be useful for the treatment of cardiac diseases, cerebrovascular diseases and hypertension.

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