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61. 发明专利

ES2303525T3 COMPUESTOS Y METODOS PARA EL TRATAMIENTO Y DIAGNOSTICO DE INFECCION POR CHLAMYDIA. 未知
公开(公告)号：ES2303525T3
公开(公告)日：2008-08-16
申请号：ES01928775
申请日：2001-04-23
申请人： CORIXA CORP
发明人： BHATIA AJAY , PROBST PETER , STROMBERG ERIKA JEAN
IPC分类号： C12N15/31 , A61K39/00 , A61K39/118 , A61K39/40 , A61K48/00 , C07K14/295 , C07K16/12 , C07K19/00 , C12N1/21 , C12N5/06 , C12N15/63 , C12Q1/68 , G01N33/571 , G01N33/68
摘要： Una composición que comprende: (a) un polipéptido que comprende: (i) la secuencia de aminoácidos de restos 8 a 660 de la Seq ID No:139, o una variante de la misma que tiene al menos 90% de identidad de secuencia con ella, determinada comparando las dos secuencias óptimamente alineadas sobre una ventana de comparación de restos 8 a 660 de la secuencia de Seq ID No:139; o (ii) una porción inmunogénica de los restos aminoacídicos 8 a 660 de la secuencia de Seq ID No:139 que tiene, al menos, 15 aminoácidos de longitud; o (b) un polinucleótido que codifica el polipéptido de (a); para uso en la diagnosis, tratamiento o prevención de infección por clamidia.

62. 发明专利

NZ549873A Compounds and methods for treatment and diagnosis of chlamydial infection by stimulating an immune response 未知
公开(公告)号：NZ549873A
公开(公告)日：2008-06-30
申请号：NZ54987301
申请日：2001-07-20
申请人： CORIXA CORP
发明人： FLING STEVEN P , PROBST PETER , BHATIA AJAY , SKEIKY YASIR A
IPC分类号： G01N33/53 , A61K31/7088 , A61K38/00 , A61K39/00 , A61K39/118 , A61K48/00 , A61P31/00 , A61P37/04 , A61P43/00 , C07K14/295 , C07K16/12 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/06 , C12N5/10 , C12N15/09 , C12N15/31 , C12Q1/06 , G01N33/566 , G01N33/569
摘要： Compositions and uses thereof of (a) a polypeptide of SEQ ID 436 or a functional variant thereof having at least 90% sequence identity thereto, as determined by comparing the two optimally aligned sequences over a window of comparison of the whole length of the sequence of SEQ ID 436; or (b) a polynucleotide encoding the polypeptide of (a) for use in stimulating an immune response in a patient

63. 发明专利

AT389020T 未知
公开(公告)号：AT389020T
公开(公告)日：2008-03-15
申请号：AT01928775
申请日：2001-04-23
申请人： CORIXA CORP
发明人： BHATIA AJAY , PROBST PETER , STROMBERG ERIKA
IPC分类号： C12N15/31 , A61K39/00 , A61K39/118 , C07K14/295 , C07K16/12 , C07K19/00 , C12N1/21 , C12N15/63 , C12Q1/68 , G01N33/68
摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.

64. 发明专利

AU2001280702B2 Compounds and methods for treatment and diagnosis of chlamydial infection 未知
公开(公告)号：AU2001280702B2
公开(公告)日：2008-01-24
申请号：AU2001280702
申请日：2001-07-20
申请人： CORIXA CORP
发明人： SKEIKY YASIR A W , PROBST PETER , BHATIA AJAY , FLING STEVEN P
IPC分类号： G01N33/53 , A61K31/7088 , A61K38/00 , A61K39/00 , A61K39/118 , A61K48/00 , A61P31/00 , A61P37/04 , A61P43/00 , C07K14/295 , C07K16/12 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/06 , C12N5/10 , C12N15/09 , C12N15/31 , C12Q1/06 , G01N33/566 , G01N33/569
摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.

65. 发明专利

DK1307564T3 未知
公开(公告)号：DK1307564T3
公开(公告)日：2007-12-27
申请号：DK01959114
申请日：2001-07-20
申请人： CORIXA CORP
发明人： FLING STEVEN P , SKEIKY YASIR A W , PROBST PETER , BHATIA AJAY
IPC分类号： C12N15/31 , G01N33/53 , A61K31/7088 , A61K31/711 , A61K38/00 , A61K39/00 , A61K39/118 , A61K39/40 , A61K48/00 , A61P31/00 , A61P37/04 , A61P43/00 , C07K14/295 , C07K16/12 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/06 , C12N5/10 , C12N15/09 , C12N15/62 , C12N15/63 , C12Q1/06 , C12Q1/68 , G01N33/566 , G01N33/569
摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.

66. 发明专利

AT373092T 未知
公开(公告)号：AT373092T
公开(公告)日：2007-09-15
申请号：AT01959114
申请日：2001-07-20
申请人： CORIXA CORP
发明人： FLING STEVEN , SKEIKY YASIR , PROBST PETER , BHATIA AJAY
IPC分类号： C12N15/31 , G01N33/53 , A61K31/7088 , A61K38/00 , A61K39/00 , A61K39/118 , A61K48/00 , A61P31/00 , A61P37/04 , A61P43/00 , C07K14/295 , C07K16/12 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/06 , C12N5/10 , C12N15/09 , C12N15/62 , C12N15/63 , C12Q1/06 , C12Q1/68 , G01N33/566 , G01N33/569
摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.

67. 发明专利

ES2255553T3 ANTIGENOS DE LEISHMANIA PARA EL TRATAMIENTO Y DIAGNOSITICO DE LA LEISHMANIASIS. 未知
公开(公告)号：ES2255553T3
公开(公告)日：2006-07-01
申请号：ES01928377
申请日：2001-04-05
申请人： CORIXA CORP
发明人： REED STEVEN G , CAMPOS-NETO ANTONIO , WEBB JOHN R , DILLON DAVIN C , SKEIKY YASIR A W , BHATIA AJAY
IPC分类号： A61K38/00 , A61K39/00 , C07K14/44 , C12N15/62
摘要： Proteína de fusión que comprende una secuencia de aminoácidos elegida dentro del grupo formado por SEQ ID NO: 95, 96 y 97. En un primer aspecto de la presente invención, se ofrece una proteína de fusión que comprende una secuencia de aminoácidos, elegida dentro del grupo formado por SEQ ID NO: 95, 96 y 97. En otro aspecto de la presente invención, se ofrece también un polinucleótido que codifica una proteína de fusión, polinucleótido que tiene una secuencia de nucleótido elegida dentro del grupo formado por SEQ ID NO: 94, 99, 98 y 100. Se presenta también un vector de expresión recombinante, que comprende el polinucleótido de la presente invención. Además, se presenta una composición farmacéutica que comprende la proteína de fusión de la presente invención o el polinucleótido de la presente invención y un vehículo fisiológicamente aceptable. En otro aspecto de la presente invención, se presenta una composición inmunógena que comprende la proteína de fusión o el polinucleótido de la presenteinvención y un inmuno-estimulante. También se ofrece la composición farmacéutica de la presente invención para utilizarla en un método de inducción de inmunidad protegida contra la leishmaniasis en un paciente. En otro aspecto, se presenta también la composición inmunógena de la presente invención, que se utiliza en un método para inducir inmunidad protectora contra la leishmaniasis en un paciente.

68. 发明专利

PL365951A1 COMPOUNDS AND METHODS FOR TREATMENT AND DIAGNOSIS OF CHLAMYDIAL INFECTION 未知
公开(公告)号：PL365951A1
公开(公告)日：2005-01-24
申请号：PL36595101
申请日：2001-07-20
申请人： CORIXA CORP
发明人： FLING STEVEN P , SKEIKY YASIR A W , PROBST PETER , BHATIA AJAY
IPC分类号： G01N33/53 , A61K31/7088 , A61K38/00 , A61K39/00 , A61K39/118 , A61K48/00 , A61P31/00 , A61P37/04 , A61P43/00 , C07K14/295 , C07K16/12 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/06 , C12N5/10 , C12N15/09 , C12N15/31 , C12Q1/06 , G01N33/566 , G01N33/569 , C07K14/195
摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.

69. 发明专利

ZA200300719B Compounds and methods for treatment and diagnosis of Chlamydial infection. 未知
公开(公告)号：ZA200300719B
公开(公告)日：2004-10-27
申请号：ZA200300719
申请日：2003-01-27
申请人： CORIXA CORP
发明人： FLING STEVEN P , PROBST PETER , SKEIKY YASIR A W , BHATIA AJAY
IPC分类号： G01N33/53 , A61K31/7088 , A61K38/00 , A61K39/00 , A61K39/118 , A61K48/00 , A61P31/00 , A61P37/04 , A61P43/00 , C07K14/295 , C07K16/12 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/06 , C12N5/10 , C12N15/09 , C12N15/31 , C12Q1/06 , G01N33/566 , G01N33/569 , C07K , C12N , C12Q , G01N , A61K
摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.

70. 发明专利

BR0112602A 未知
公开(公告)号：BR0112602A
公开(公告)日：2004-02-17
申请号：BR0112602
申请日：2001-07-20
申请人： CORIXA CORP
发明人： FLING STEVEN P , SKEIKY YASIR A W , PROBST PETER , BHATIA AJAY
IPC分类号： G01N33/53 , A61K31/7088 , A61K38/00 , A61K39/00 , A61K39/118 , A61K48/00 , A61P31/00 , A61P37/04 , A61P43/00 , C07K14/295 , C07K16/12 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/06 , C12N5/10 , C12N15/09 , C12N15/31 , C12Q1/06 , G01N33/566 , G01N33/569 , C07K14/195
摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.

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