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    • 69. 发明申请
    • ANTI-WRINKLE COMPOSITION
    • 防皱组合物
    • US20070243221A1
    • 2007-10-18
    • US11733786
    • 2007-04-11
    • Alexandre CavezzaPhilippe BretonMaria Dalko
    • Alexandre CavezzaPhilippe BretonMaria Dalko
    • A61K8/49C07D211/56A61K31/445
    • C07D211/58A61K8/4926A61K31/445A61Q19/08
    • The present invention relates to the cosmetic use of at least one 4-aminopiperidine compound of formula (I) in which: Alk1 and Alk2 denote a C1-C10 alkylene radical; Ar1 denotes a phenyl group optionally substituted with one or more radicals, which may be identical or different, chosen from —F, —CF3, —R1, —OR1, —NR1R2; Ar2 denotes a phenyl group optionally substituted with one or more radicals, which may be identical or different, chosen from —F, —CF3, —NR1R2; R denotes a hydrogen atom or a C1-C10 alkyl radical; R1 and R2 denoting a C1-C7 alkyl radical; and the salts, optical isomers and solvates thereof, as an agent for combating wrinkles, especially expression wrinkles, and/or for decontracting the skin and/or relaxing the features. The invention also relates to a cosmetic composition containing such a compound and to the corresponding novel compounds.
    • 本发明涉及至少一种式(I)的4-氨基哌啶化合物的化妆品用途,其中:Alk 1和Alk 2表示C 1 C 1 -C 10亚烷基; Ar 1表示任选被一个或多个基团取代的苯基,其可以相同或不同,选自-F,-CF 3 - , - R 1 -OR 1,-NR 1 R 2,R 2,R 2,R 2, Ar 2表示任选被一个或多个基团取代的苯基,其可以相同或不同,选自-F,-CF 3 N,-NR 1 R 2 2; R表示氢原子或C 1 -C 10烷基; R 1和R 2表示C 1 -C 7烷基; R 1,R 2,R 2, 及其盐,光学异构体和溶剂化物,作为抗皱纹,特别是表现皱纹的药剂和/或用于使皮肤脱皮和/或松弛特征。 本发明还涉及含有这种化合物和相应的新化合物的化妆品组合物。