专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

61. 发明授权

US06751503B1 Methods and systems for treating patients with congestive heart failure (CHF) 有权
标题翻译：治疗充血性心力衰竭（CHF）患者的方法和系统
公开(公告)号：US06751503B1
公开(公告)日：2004-06-15
申请号：US09999408
申请日：2001-11-01
申请人： Mark W. Kroll
发明人： Mark W. Kroll
IPC分类号： A61N1365
CPC分类号： A61N1/3627 , A61N1/36521 , A61N1/36535 , A61N1/36542 , A61N1/3684
摘要： Various embodiments provide techniques and systems that can ensure that patients with congestive heart failure receive pacing therapy that optimizes their hemodynamic performance in view of various variables that pertain to the patient. Exemplary variables can include, without limitation, the time of day, patient posture and activity level.
摘要翻译：各种实施例提供的技术和系统可以确保充血性心力衰竭患者接受起搏治疗，根据与患者相关的各种变量来优化其血流动力学性能。示例性变量可以包括但不限于一天中的时间，患者姿势和活动水平。

62. 发明授权

US06748261B1 Implantable cardiac stimulation device for and method of monitoring progression or regression of heart disease by monitoring interchamber conduction delays 有权
标题翻译：通过监测车间传导延迟，可植入心脏刺激装置和监测心脏病进展或消退的方法
公开(公告)号：US06748261B1
公开(公告)日：2004-06-08
申请号：US09675462
申请日：2000-09-28
申请人： Mark W. Kroll , Joseph J. Florio , Gene A. Bornzin , Euljoon Park , Kerry A. Bradley
发明人： Mark W. Kroll , Joseph J. Florio , Gene A. Bornzin , Euljoon Park , Kerry A. Bradley
IPC分类号： A61B504
CPC分类号： A61N1/3627 , A61B5/0031 , A61B5/0456 , A61B5/046 , A61N1/3684
摘要： A system and method, for use in an implantable cardiac stimulation device, monitors progression or regression in heart disease such as congestive heart failure. The system includes a sensing circuit that derives an electrogram signal indicative of the electrical activity of the patient's heart. A processor processes the electrogram signal to determine interchamber conduction delays which are then stored in memory. The stored interchamber conduction delays may be later retrieved by way of a telemetry circuit. Relative changes in the interchamber conduction delays, over time, are indicative of progression or regression in the heart disease. The relative changes in the interchamber conduction delays may be further used to automatically adjust pacing parameters of the implantable cardiac stimulation device.
摘要翻译：用于可植入心脏刺激装置的系统和方法监测心脏疾病如充血性心力衰竭的进展或消退。该系统包括感测电路，其导出指示患者心脏的电活动的电描绘信号。处理器处理电描记图信号以确定然后存储在存储器中的车间传导延迟。存储的车间传导延迟可以稍后通过遥测电路检索。随着时间的推移，间歇传导延迟的相对变化表明心脏病发展或消退。室间传导延迟的相对变化可以进一步用于自动调整可植入心脏刺激装置的起搏参数。

63. 发明授权

US06580915B1 Aircraft internal EMI detection and location 失效
标题翻译：飞机内部EMI检测和位置
公开(公告)号：US06580915B1
公开(公告)日：2003-06-17
申请号：US09406067
申请日：1999-09-24
申请人： Mark W. Kroll
发明人： Mark W. Kroll
IPC分类号： H04Q720
CPC分类号： G01S5/14
摘要： A circuit and method to locate a cellular phone or noisy laptop computer in an aircraft uses and antenna each in the front and back of the plane. Arrival time differences of cellular phone pulses are used to locate the offending phone. Three receivers are used to locate a cell phone in a theater audience. Broad band correlation is used to locate an offending laptop computer.
摘要翻译：在飞行器中定位蜂窝电话或噪声笔记本电脑的电路和方法在飞机的前面和后面使用天线。蜂窝电话脉冲的到达时间差异用于定位违规手机。三个接收机用于在剧院观众中定位手机。宽带相关用于定位违规笔记本电脑。

64. 发明授权

US06560974B2 Nitrogen-based refrigerator crisper 失效
公开(公告)号：US06560974B2
公开(公告)日：2003-05-13
申请号：US09951812
申请日：2001-09-11
申请人： Mark W. Kroll , Thorstein Holt
发明人： Mark W. Kroll , Thorstein Holt
IPC分类号： F24F316
CPC分类号： F25D17/042 , A23L3/3418 , A23L3/363 , B01D53/047 , B01D53/22 , B01D53/261 , B01D2253/108 , B01D2253/116 , B01D2253/25 , B01D2256/10 , B01D2257/102 , B01D2257/104 , B01D2257/80 , B01D2259/40009
摘要： A refrigerator crisper drawer based on an increased nitrogen concentration. This nitrogen concentration necessarily depletes the oxygen thus reducing the opportunities for food to oxidize or “brown.”

65. 发明授权

US6132426A Temperature and current limited ablation catheter 失效
标题翻译：温度和电流限制消融导管
公开(公告)号：US6132426A
公开(公告)日：2000-10-17
申请号：US72945
申请日：1998-05-05
申请人： Mark W. Kroll
发明人： Mark W. Kroll
IPC分类号： A61B18/12 , A61B18/18
CPC分类号： A61B18/1206 , A61B2018/0066 , A61B2018/1273
摘要： An ablation catheter of the present invention includes a means for limiting a current and temperature at a target tissue site. The ablation catheter includes a tip electrode at its distal end, and a positive temperature coefficient (PTC) device between the distal end and a proximal end of the catheter. Both the PTC device and electrode are electrically connected via a conductor extending within the catheter.
摘要翻译：本发明的消融导管包括用于限制目标组织部位的电流和温度的装置。消融导管在其远端包括尖端电极，以及在导管的远端和近端之间的正温度系数（PTC）装置。 PTC器件和电极都通过在导管内延伸的导体电连接。

66. 发明授权

US6041255A Disposable external defibrillator 失效
标题翻译：一次性外用除颤器
公开(公告)号：US6041255A
公开(公告)日：2000-03-21
申请号：US61755
申请日：1998-04-16
申请人： Mark W. Kroll
发明人： Mark W. Kroll
IPC分类号： A61N1/39 , H01M2/10 , H01M6/36 , H01M10/42
CPC分类号： H01M10/4257 , A61N1/39 , A61N1/3975 , H01M10/4264 , H01M6/36 , H01M2/1022
摘要： External defibrillator using a thermal battery. The thermal battery provides an essentially infinite shelf life since it is internally insulated by dry salts until activation. The high power output of the thermal battery allows the use of leaky unreformed capacitors since they can be quickly recharged in spite of their current leakage. This obviates the energy intensive process of regular capacitor reforming. The extreme power output of the thermal battery also allows the therapy of essentially continuous shocks as it can recharge the capacitors in typically 5 seconds instead of the 15 to 30 seconds in conventional defibrillators.
摘要翻译：使用热电池的外部除颤器。热电池提供了基本上无限的保质期，因为它在内部被干盐绝缘直到活化。热电池的高功率输出允许使用漏电的未成形电容器，因为它们可以快速充电，尽管它们的电流泄漏。这消除了常规电容器重整的能量密集过程。热电池的极端功率输出还允许治疗基本上持续的冲击，因为它可以在常规除颤器中通常在5秒内而不是15至30秒对电容器充电。

67. 发明授权

US5957956A Implantable cardioverter defibrillator having a smaller mass 失效
标题翻译：植入式心律转复除颤器质量较小
公开(公告)号：US5957956A
公开(公告)日：1999-09-28
申请号：US963154
申请日：1997-11-03
申请人： Mark W. Kroll , Theodore P. Adams , Kenneth M. Anderson , Charles U. Smith
发明人： Mark W. Kroll , Theodore P. Adams , Kenneth M. Anderson , Charles U. Smith
IPC分类号： A61N1/375 , A61N1/39 , H01M2/10 , H01M6/50 , H01M16/00 , A61N1/18
CPC分类号： A61N1/375 , A61N1/3956 , A61N1/3758 , H01M16/00 , H01M2/1066 , H01M6/5016
摘要： A capacitor-discharge implantable cardioverter defibrillator (ICD) has a relatively smaller mass of less than about 120 grams. The smaller mass of the ICD is achieved by selecting and arranging the internal components of the ICD to deliver a maximum defibrillation countershock optimized in terms of a minimum physiologically effective current (I.sub.pe), rather than a minimum defibrillation threshold energy (DFT). As a result of the optimization in terms of a minimum effective current I.sub.pe, there is a significant decrease in the maximum electrical charge energy (E.sub.c) that must be stored by the capacitor of the ICD to less than about 30 Joules, even though a higher safety margin is provided for by the device. Due to this decrease in the maximum E.sub.c, as well as corollary decreases in the effective capacitance value required for the capacitor and the net energy storage required of the battery, the overall displacement volume of the ICD is reduced to the point where subcutaneous implantation of the device in the pectoral region of human patients is practical. The size of the capacitor is reduced because the effective capacitance required can be less than about 125 .mu.F. By optimizing both the charging time and the countershock duration for the smaller maximum E.sub.c, the size of the battery is reduced because the total energy storage capacity can be less than about 1.0 Amp-hours. In the preferred embodiment, the charging time for each defibrillation countershock is reduced to less than about 10 seconds and the pulse duration of the countershock is reduced to less than about 6 milliseconds.
摘要翻译：电容放电植入式心律转复除颤器（ICD）的质量相对较小，小于约120克。通过选择和布置ICD的内部部件来实现ICD的较小质量，以提供根据最小生理有效电流（Ipe）而不是最小除颤阈值能量（DFT）优化的最大除颤抗倒伏。作为最小有效电流Ipe优化的结果，ICD的电容器必须存储的最大电荷能量（Ec）显着降低到小于约30焦耳，即使较高的设备提供安全余量。由于最大Ec的这种减小以及电容器所需的有效电容值和电池所需的净能量存储的必然减小，ICD的总位移体积减少到皮下植入在人类胸腔的器官是实用的。电容器的尺寸减小，因为所需的有效电容可以小于约125μF。通过优化较小的最大Ec的充电时间和反冲时间，电池的尺寸减小，因为总能量存储容量可以小于约1.0安培小时。在优选实施例中，每个去纤维颤动反射的充电时间减少到小于约10秒，并且该反冲的脉冲持续时间减小到小于约6毫秒。

68. 发明授权

US5906633A System for delivering rounded low pain therapeutic electrical waveforms to the heart 失效
标题翻译：向心脏传递圆滑的低疼痛治疗电波形的系统
公开(公告)号：US5906633A
公开(公告)日：1999-05-25
申请号：US64422
申请日：1998-04-22
申请人： Gabriel Mouchawar , Robert J. Sweeney , Mark W. Kroll
发明人： Gabriel Mouchawar , Robert J. Sweeney , Mark W. Kroll
IPC分类号： A61N1/39
CPC分类号： A61N1/3956 , A61N1/3906 , A61N1/3912 , Y10S128/908
摘要： A system for delivering low pain cardioversion shocks to the heart wherein the system provides a waveform to the heart that is biphasic and has rounded leading and trailing edges. The rounded leading and trailing edges are believed to decrease the discomfort experienced by the patient. In one embodiment, the circuit has a two capacitors connected in parallel with each other and with an H-bridge. The two capacitors are connected via a switch that can be closed so as to simultaneously charge one capacitor from the other while simultaneously applying voltage to the H-bridge. The circuit also includes a dump resistor that can be connected in parallel with the capacitors so as to increase the rounding of the trailing edges of the waveform. In another embodiment, controllable switches can also be included so as to be able to connect the capacitors in series and apply a sharp peak defibrillation waveform to the heart.
摘要翻译：用于向心脏递送低疼痛心脏复律冲击的系统，其中系统向心脏提供双相并具有圆形前缘和后缘的波形。认为圆形的前缘和后缘减少了患者所遭受的不适。在一个实施例中，该电路具有彼此并联并具有H桥的两个电容器。两个电容器通过可以关闭的开关连接，以便同时向另一个电容器充电，同时向H桥施加电压。该电路还包括可与电容器并联连接的转储电阻器，以增加波形后沿的舍入。在另一个实施例中，还可以包括可控开关，以便能够串联连接电容器，并向心脏施加尖锐的除颤波形。

69. 发明授权

US5827326A Implantable cardioverter defibrillator having a smaller energy storage capacity 失效
标题翻译：具有较小能量储存能力的植入式心律转复除颤器
公开(公告)号：US5827326A
公开(公告)日：1998-10-27
申请号：US412920
申请日：1995-03-29
申请人： Mark W. Kroll , Theodore P. Adams , Kenneth M. Anderson , Charles U. Smith
发明人： Mark W. Kroll , Theodore P. Adams , Kenneth M. Anderson , Charles U. Smith
IPC分类号： A61N1/375 , A61N1/378 , A61N1/39 , H01M2/10 , H01M6/50 , H01M16/00
CPC分类号： A61N1/375 , A61N1/3787 , A61N1/3931 , A61N1/3956 , A61N1/3975 , H01M16/00 , A61N1/3758 , A61N1/3906 , A61N1/3912 , H01M2/1066 , H01M6/5016
摘要： A capacitor-discharge implantable cardioverter defibrillator (ICD) has a relatively smaller energy storage capacity of less than about 1.0 Amp-hours. The smaller energy storage capacity of the ICD is achieved by selecting and arranging the internal components of the ICD to deliver a maximum defibrillation countershock optimized in terms of a minimum physiologically effective current (I.sub.pe) rather than a minimum defibrillation threshold energy (DFT). As a result of the optimization in terms of a minimum effective current I.sub.pe, there is a significant decrease in the maximum electrical charge energy (E.sub.c) that must be stored by the capacitor of the ICD to less than about 30 Joules, even though a higher safety margin is provided for by the device. Due to this decrease in the maximum E.sub.c, as well as corollary decreases in the effective capacitance value required for the capacitor and the net energy storage required of the battery, the overall displacement volume of the ICD is reduced to the point where subcutaneous implantation of the device in the pectoral region of human patients is practical. The size of the capacitor is reduced because the effective capacitance required can be less than about 125 .mu.F. By optimizing both the charging time and the countershock duration for the smaller maximum E.sub.c, the size of the battery is reduced because the total energy storage capacity can be less than about 1.0 Amp-hours. In the preferred embodiment, the charging time for each defibrillation countershock is reduced to less than about 10 seconds and the pulse duration of the countershock is reduced to less than about 6 milliseconds.
摘要翻译：电容放电植入式心律转复除颤器（ICD）具有小于约1.0安培小时的相对较小的储能能力。通过选择和布置ICD的内部部件来实现ICD的较小的能量存储容量，以提供根据最小生理有效电流（Ipe）而不是最小除颤阈值能量（DFT）优化的最大除颤反相。作为最小有效电流Ipe优化的结果，ICD的电容器必须存储的最大电荷能量（Ec）显着降低到小于约30焦耳，即使较高的设备提供安全余量。由于最大Ec的这种减小以及电容器所需的有效电容值和电池所需的净能量存储的必然减小，ICD的总位移体积减少到皮下植入在人类胸腔的器官是实用的。电容器的尺寸减小，因为所需的有效电容可以小于约125μF。通过优化较小的最大Ec的充电时间和反冲时间，电池的尺寸减小，因为总能量存储容量可以小于约1.0安培小时。在优选实施例中，每个去纤维颤动反射的充电时间减少到小于约10秒，并且该反冲的脉冲持续时间减小到小于约6毫秒。

70. 发明授权

US5814075A Method and apparatus for optimizing source allocation within an implantable cardioverter-defibrillator 失效
标题翻译：用于优化植入式心律转复除颤器内源分配的方法和装置
公开(公告)号：US5814075A
公开(公告)日：1998-09-29
申请号：US877046
申请日：1997-06-17
申请人： Mark W. Kroll
发明人： Mark W. Kroll
IPC分类号： A61N1/39
CPC分类号： A61N1/3937 , A61N1/3962
摘要： A power control system is described for use in an implantable cardioverter-defibrillator (ICD) having a low-power cell and a high-power cell. The power control system includes a fuzzy logic controller for gradually varying the relative amounts of energy drawn from the low- and high-power cells based upon a selected function to be performed by the ICD and upon various operational parameters of the ICD. Example functions include cardioversion therapy, cardiac defibrillation, cardiac pacing, cardiac monitoring and capacitor reformation. Example operational parameters include the remaining capacities of the low- and high-power cells, the amount of time since implant of the ICD, the number of defibrillation shocks already delivered, and the amount of pacing energy previously utilized. In each case, the fuzzy logic controller applies a set of fuzzy logic rules to determine the relative amounts of energy to be drawn from the two power cells to optimize energy source allocation and to extend the overall longevity of the ICD.
摘要翻译：电力控制系统被描述用于具有低功率电池和高功率电池的可植入心律转复除颤器（ICD）。功率控制系统包括模糊逻辑控制器，用于基于由ICD执行的所选择的功能和ICD的各种操作参数逐渐改变从低功率单元和大功率单元获取的能量的相对量。示例功能包括心脏复律治疗，心脏除颤，心脏起搏，心脏监测和电容器重建。示例性操作参数包括低功率电池和大功率电池的剩余容量，ICD植入后的时间量，已经输送的除颤电击的数量以及以前使用的起搏能量。在每种情况下，模糊逻辑控制器应用一组模糊逻辑规则来确定要从两个电力单元抽取的能量的相对量，以优化能源分配并延长ICD的整体寿命。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式