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    • 62. 发明申请
    • Compartmentalized device for cell culture, cell processing, and sample dialysis
    • 用于细胞培养,细胞处理和样品透析的分隔装置
    • US20050101009A1
    • 2005-05-12
    • US10985339
    • 2004-11-10
    • John WilsonDan WelchAlison RobeckDouglas Page
    • John WilsonDan WelchAlison RobeckDouglas Page
    • C12M1/12C12M1/24C12M3/04C12M3/06
    • C12M27/12C12M23/08C12M23/34
    • A versatile compartmentalized cell culture device, with a selectively permeable membrane separating the compartments, provides many attributes relative to traditional devices. It can be configured for high-density cell culture, co-culture, and sample dialysis while rolling or standing still. It can also be configured for continuous movement of liquid between compartments. The wide combination of attributes not found in other membrane based cell culture and bioprocessing devices includes more cell capacity, more cell secreted product capacity, higher cell and product density, increased medium capacity, minimized use of exogenous growth factors, compatibility with standard cell culture equipment and protocols, increased scale up efficiency, capacity to function when rolling or standing still, capacity for perfusion without the need for pumps, and more efficient sample dialysis.
    • 具有分离隔室的选择性渗透膜的多功能隔室细胞培养装置相对于传统装置提供许多属性。 它可以配置为在滚动或静置时进行高密度细胞培养,共培养和样品透析。 它也可以配置为在隔室之间连续移动液体。 在其他基于膜的细胞培养和生物处理装置中没有发现的属性的广泛组合包括更多的细胞容量,更多的细胞分泌产物能力,更高的细胞和产物密度,增加的培养基能力,最小化外源生长因子的使用,与标准细胞培养设备的相容性 和方案,增加放大效率,滚动或静止时功能的能力,无需泵的灌注能力,以及更有效的样品透析。
    • 66. 发明授权
    • Three-dimensional polyhedral jigsaw-type puzzle
    • 三维多面拼图拼图
    • US5104125A
    • 1992-04-14
    • US464905
    • 1990-01-16
    • John Wilson
    • John Wilson
    • A63F9/12
    • A63F9/12A63F2009/124A63F2250/482
    • A multi-set assembly puzzle (100) whose flat pieces correspond to the panels of a soccer ball. A 32 piece complement comprises 20 hexagons (102) and 12 pentagons (104). Grooves (112) in all polygon sides (110) must have a cylinder (114) attached in it's right (R) else left (L) portions. Sides (110) adjoin only RR else LL. Adjoining pieces may be coupled by inserting a single connecting pin (120) through their aligned cylinder's centers (118). The Rs and Ls of the polygons' sides (110) may be configured to produce 22 different subspecies. The sides (110) are grouped in 90 adjoining pairs which are randomly assigned R else L. The polygon subspecies are then found by examining the Rs and Ls of their sides, and their quantities become the specification for the complement. Successive specifications are compared to all previous specifications. Identical specifications are eliminated, but the former set has another solution, and is rated less difficult. A set, its specification, its solutions, and its difficulty rating are assocciated by a serial number.
    • 多组合拼图(100),其平片对应于足球的面板。 32片补体包括20个六边形(102)和12个五边形(104)。 所有多边形(110)中的凹槽(112)必须具有连接在其右侧(R)左侧(L)部分的圆柱体(114)。 边(110)仅毗邻RR else LL。 可以通过将单个连接销(120)插入其对准的气缸的中心(118)来联接相邻件。 多角形边(110)的Rs和Ls可以被配置成产生22个不同的亚种。 侧面(110)被分组成90个邻接对,随机分配为R else L。然后通过检查它们的边的Rs和Ls来找到多边形亚种,并且它们的数量成为补码的规范。 将以前的规格与以前的规格进行比较。 消除了相同的规格,但是前者具有另一种解决方案,而且评级较难。 一套,其规格,其解决方案和难度等级由序列号分配。
    • 67. 发明授权
    • Framing form and clamp
    • 框架形式和夹具
    • US4047710A
    • 1977-09-13
    • US748366
    • 1976-12-07
    • John Wilson
    • John Wilson
    • B25B1/20
    • B25B1/205
    • A framing form and clamp includes a support or base having a plurality of guideways for mounting framing blocks. A belt cooperating with a ratchet assembly surrounds the blocks. In forming and clamping a frame, frame molding strips are associated with the appropriate framing blocks of the framing form and clamp, the size and number of the strips depending upon the dimension and shape of the desired frame. The belt is tightly wound around the framing blocks to secure the strips while the corners of the adjacent strips are permanently connected to form the frame.
    • 框架形式和夹具包括具有用于安装框架块的多个导轨的支撑件或底座。 与棘轮组件配合的皮带围绕着该块。 在形成和夹紧框架时,框架模制条与框架形式和夹具的适当框架块相关联,条带的尺寸和数量取决于所需框架的尺寸和形状。 带子紧紧地卷绕在框架块上以固定条带,同时相邻条带的角部被永久连接以形成框架。