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    • 61. 发明申请
    • Rigid primer bulb pump
    • 刚性底漆灯泡泵
    • US20090199806A1
    • 2009-08-13
    • US12313268
    • 2008-11-18
    • Christopher BrownMarvin Peplow
    • Christopher BrownMarvin Peplow
    • F02M1/16
    • F02M37/16B63H21/38F02B61/045
    • A hand operated primer pump for small marine or other engines generally spark ignition engines used on stern drive boats that prevents transfer of hydrocarbons into the atmosphere. The primer generally mimics and replaces prior art rubber primer bulbs in general shape and possibly color, although it can be made in any shape or color. It generally contains a pump that delivers a precise measured amount of fuel with each stroke of the actuator. The primer can have an ergonomically designed actuator that creates the farthest distance from a fulcrum point for maximum leverage and hence, maximum ease of use. The primer is generally designed with a continuous molded fuel path to seal any source of hydrocarbon leakage as well as being made from materials that prevent transfer of hydrocarbons to the atmosphere.
    • 用于小型船舶或其他发动机的手动底漆泵通常会使用于船尾驱动船上的点火发动机,以防止碳氢化合物进入大气。 引物通常模拟和替代现有技术的橡胶底漆,其总体形状和可能的颜色,尽管它可以制成任何形状或颜色。 它通常包含一个泵,该致动器的每个行程都会传送精确测量的燃油量。 底漆可以具有符合人体工程学设计的执行器,可以创建距离支点最远的距离,以获得最大的杠杆作用,因此最大限度的方便使用。 底漆通常设计有连续模制的燃料路径,以密封任何烃类泄漏源,并且由防止烃转移到大气中的材料制成。
    • 66. 发明申请
    • Determination of a Measure of a Glycation End-Product or Disease State Using Tissue Fluorescence
    • 使用组织荧光测定糖化终产物或疾病状态的测量
    • US20070088205A1
    • 2007-04-19
    • US11561380
    • 2006-11-17
    • Edward HullMarwood EdigerChristopher BrownJohn MaynardRobert Johnson
    • Edward HullMarwood EdigerChristopher BrownJohn MaynardRobert Johnson
    • A61B5/00
    • A61B5/1455A61B5/0059A61B5/0064A61B5/0066A61B5/0068A61B5/0071A61B5/0075A61B5/14532A61B5/412A61B5/441
    • A method of detefnnining a measure of a tissue state (e.g., glycation end-product or disease state) in an individual. A portion of the tissue of the individual is illuminated with excitation light, then light emitted by the tissue due to fluorescence of a chemical with the tissue responsive to the excitation light is detected. The detected light can be combined with a model relating fluorescence with a measure of tissue state to determine a tissue state. The invention can comprise single wavelength excitation light, scanning of excitation light (illuminating the tissue at a plurality of waveliengths), detection at a single wavelength, scanning of detection wavelengths (detecting emitted light at a plurality of wavelengths), and combinations thereof. The invention also can comprise correction techniques that reduce determination errors due to detection of light other than that from fluorescence of a chemical in the tissue. For example, the reflectance of the tissue can lead to errors if appropriate correction is not employed. The invention can also comprise a variety of models relating fluorescence to a measure of tissue state, including a variety of methods for generating such models. Other biologic information can be used in combination with the fluorescence properties to aid in the determination of a measure of tissue state. The invention also comprises apparatuses suitable for carrying out the method, including appropriate light sources, detectors, and models (for example, implemented on computers) used to relate detected fluorescence and a measure of tissue state.
    • 确定个体中组织状态(例如,糖基化终产物或疾病状态)的量度的方法。 用激发光照射个体组织的一部分,然后检测由组织响应于激发光的化学物质的荧光而由组织发出的光。 检测到的光可以与将荧光与组织状态的测量相关联的模型组合以确定组织状态。 本发明可以包括单波长激发光,激发光的扫描(以多个波长照射组织),单个波长的检测,检测波长的扫描(检测多个波长的发射光)及其组合。 本发明还可以包括校正技术,其减少由于检测到除了组织中的化学物质的荧光以外的光的测定误差。 例如,如果不采用适当的校正,组织的反射率可能导致错误。 本发明还可以包括将荧光与组织状态的测量相关联的各种模型,包括用于产生这种模型的各种方法。 其他生物信息可与荧光性质结合使用,有助于测定组织状态。 本发明还包括适于执行该方法的装置,包括用于检测荧光和组织状态测量的适当的光源,检测器和模型(例如,在计算机上实现)。