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    • 67. 发明公开
    • IMPLANTABLE GAS PROPELLED BENEFICIAL AGENT DELIVERY DEVICE
    • IMPLANTIERBARES GASDRUCKGETRIEBENESGERÄTZUR WIRKSTOFFVERABREICHUNG
    • EP1035839A4
    • 2000-09-20
    • EP98940798
    • 1998-08-06
    • CERAMATEC INC
    • JOSHI ASHOKWOLD TRUMANDI PALMA GIORGIO
    • A61K9/22A61D7/00A61M13/00A61M31/00A61M37/00
    • A61M31/002
    • A controlled delivery device (20) for holding and administering a biologically active agent includes a housing (22) having a first end portion (26), a second end portion (28), and a port (30) associated with the housing (22). Enclosed within the housing (22) is a displacing member (42), a chemical or electrochemical gas generating cell (44), activation, and control circuitry (46). The electrochemical or chemical cell (44) generates gas within the housing (22) forcing the displacing member (42) against the beneficial agents contained within the housing (22) and forcing the beneficial agents through an outlet port (30) and into an animal's body cavity at a predetermined rate. An anchoring mechanism (24) may be associated with the housing (22) for securing the housing (22) inside the body cavity of the animal being treated. Also disclosed are methods of delivering the beneficial agents into the animal's body cavity using the delivery device of the present invention.
    • 用于保持和施用生物活性剂的受控递送装置(20)包括具有第一端部(26),第二端部(28)和与壳体(22)相关联的端口(30)的壳体(22) )。 封闭在壳体(22)内的是位移构件(42),化学或电化学气体生成单元(44),激活和控制电路(46)。 电化学或化学电池(44)在壳体(22)内产生气体,迫使位移构件(42)抵靠包含在壳体(22)内的有益物质并迫使有益物质通过出口端口(30)并进入动物的 体腔以预定的速度。 锚定机构(24)可以与壳体(22)相关联,以将壳体(22)固定在待处理动物的体腔内。 还公开了使用本发明的递送装置将有益剂递送到动物体腔中的方法。
    • 68. 发明公开
    • COMPOSITE ALKALI ION CONDUCTIVE SOLID ELECTROLYTE
    • ZUSAMMUSTRETZTER ALKALI-IONEN LEITENDER FESTELEKTROLYT
    • EP2804967A4
    • 2015-12-30
    • EP13738140
    • 2013-01-15
    • CERAMATEC INC
    • JOSHI ASHOKBHAVARAJU SAI
    • C25B13/04H01M10/0565
    • C25B13/04H01M6/185H01M8/1016H01M10/052H01M10/0562
    • An electrochemical cell having a composite alkali ion-conductive electrolyte membrane. Generally, the cell includes a catholyte compartment and an anolyte compartment that are separated by the composite alkali ion-conductive electrolyte membrane. The composite electrolyte membrane includes a layer of alkali ion-conductive material and one or more layers of alkali intercalation compound which is chemically stable upon exposure to a chemically reactive anolyte solution or catholyte solution thereby protecting the layer of alkali ion-conductive material from unwanted chemical reaction. The layer of alkali intercalation compound conducts alkali ions. The cell may operate and protect the alkali ion-conductive material under conditions that would be adverse to the material if the intercalation compound were not present. The composite membrane may include a cation conductor layer having additional capability to protect the composite electrolyte membrane from adverse conditions.
    • 一种具有复合碱离子传导电解质膜的电化学电池。 通常,电池包括被复合碱性离子传导性电解质膜分离的阴极电解液室和阳极电解液室。 复合电解质膜包括一层碱性离子传导材料和一层或多层碱插层化合物,其在暴露于化学反应性阳极电解液或阴极电解液中时化学稳定,从而保护碱性离子传导材料层免受不希望的化学物质 反应。 碱插层化合物层传导碱离子。 如果插入化合物不存在,电池可以在对材料有害的条件下操作和保护碱性离子传导材料。 复合膜可以包括具有保护复合电解质膜免受不利条件的附加能力的阳离子导体层。