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61. 发明申请

US20070265551A1 Method for delivering a catheter to a target in the brain of a patient and guide wire for a microcatheter for insertion in the brain of a patient 审中-公开
标题翻译：用于将导管输送到患者脑中的靶和用于插入患者脑的微导管的导丝的方法
公开(公告)号：US20070265551A1
公开(公告)日：2007-11-15
申请号：US11789229
申请日：2007-04-24
申请人： Marcus Pfister
发明人： Marcus Pfister
IPC分类号： A61M25/00
CPC分类号： A61M25/09 , A61L31/14 , A61L2400/12 , A61M25/0127 , A61M2025/09133
摘要： The movement of catheters and guide wires for catheters with the aid of magnets is known from the field of cardiology. Conventional magnets are, as a result of their size, not suited to being inserted into the brain of patient, because the vessels there are smaller than the cardiac vessels. To enable the navigation methods proven in cardiology also to be used in neurology, the invention provides a microcatheter having a guide wire, which features magnetic nanoparticles. The magnetic nanoparticles can be provided in the form of a ferrofluid or also as diamond nanoparticles in powder form. This enables navigation of the guide wire and thus ultimately of the catheter in the brain from the outside by way of magnetic fields.
摘要翻译：借助于磁体，用于导管的导管和引导线的运动从心脏病学领域是已知的。作为其尺寸的结果，常规磁体不适于插入患者的脑中，因为其中的血管小于心脏血管。为了使得在心脏病学中证明的导航方法也可用于神经学，本发明提供了一种具有导线的微导管，其具有磁性纳米颗粒。磁性纳米颗粒可以以铁磁流体的形式提供，或者以粉末形式提供为金刚石纳米颗粒。这使得能够通过磁场从外部导航引导线并且因此导致脑中的导管。

62. 发明申请

US20070167706A1 Method and apparatus for visually supporting an electrophysiological catheter application in the heart by means of bidirectional information transfer 审中-公开
标题翻译：通过双向信息传递在心脏中视觉上支持电生理导管应用的方法和装置
公开(公告)号：US20070167706A1
公开(公告)日：2007-07-19
申请号：US11516138
申请日：2006-09-06
申请人： Jan Boese , Andreas Meyer , Marcus Pfister , Norbert Rahn
发明人： Jan Boese , Andreas Meyer , Marcus Pfister , Norbert Rahn
IPC分类号： A61B5/05
CPC分类号： G06T11/008 , A61B18/1492 , A61B90/36 , A61B2017/00053 , A61B2018/00839 , A61B2090/364
摘要： Method and apparatus for visually supporting an electrophysiological catheter application in the heart by means of bidirectional information transfer The present invention relates to a method and apparatus for visually supporting an electrophysiological catheter application in the heart. For the method, 3D image data of at least the heart, which is captured using a tomographic 3D imaging method prior to execution of the catheter application, and electroanatomical 3D mapping data of at least one area of the heart to be treated, which is captured during execution of the catheter application, is provided and the electroanatomical 3D mapping data and/or at least part of the 3D image data is displayed during execution of the catheter application. The method is characterized in that, in the electroanatomical 3D mapping data and/or the 3D image data, the contour of one or more areas (3) relevant to the catheter application is captured and transferred to the other system in each case on which the areas (3) are superimposed as a single polyline (5) in the representation (2, 4) of the electroanatomical 3D mapping data and/or 3D image data. The method proposed and the associated apparatus provide the user with a rapid overview of the areas relevant to the catheter application.
摘要翻译：通过双向信息转移在心脏中视觉上支持电生理学导管应用的方法和装置技术领域本发明涉及用于在心脏中视觉上支持电生理导管应用的方法和装置。对于该方法，在执行导管应用之前使用断层摄影3D成像方法捕获的至少心脏的3D图像数据以及被捕获的心脏的至少一个区域的电解剖3D绘图数据在执行导管应用期间，并且在执行导管应用期间显示电解剖3D绘图数据和/或3D图像数据的至少一部分。该方法的特征在于，在电解剖3D图数据和/或3D图像数据中，与导管应用相关的一个或多个区域（3）的轮廓被捕获并传送到另一个系统，在每个情况下，在电解剖3D绘图数据和/或3D图像数据的表示（2,4）中，区域（3）被叠加为单个折线（5）。提出的方法和相关联的装置向用户提供与导管应用相关的区域的快速概述。

63. 发明申请

US20070083102A1 Method for the graphical representation of a medical instrument inserted at least partially into an object under examination 有权
标题翻译：用于至少部分地插入被检查物体的医疗仪器的图形表示的方法
公开(公告)号：US20070083102A1
公开(公告)日：2007-04-12
申请号：US11522261
申请日：2006-09-15
申请人： Marcus Pfister , Bernhard Sandkamp
发明人： Marcus Pfister , Bernhard Sandkamp
IPC分类号： A61B5/05
CPC分类号： A61B90/36 , A61B6/12 , A61B6/4441 , A61B6/541 , A61B2090/364 , G06T7/70 , G06T2207/10072 , G06T2207/30004 , G06T2207/30021
摘要： The invention provides a method for the graphical representation of a medical instrument (3) inserted at least partially into an object under examination (2), with an image (4) representing the medical instrument (3) being generated, in that the instrument image (4) is vectorized (V), with the medical instrument (3) being represented as a polyline (8, 8′).
摘要翻译：本发明提供了一种用于至少部分地插入被检查物体（2）中的医疗器械（3）的图形表示的方法，其中生成了代表医疗器械（3）的图像（4），仪器图像（4）被矢量化（V），医疗器械（3）被表示为折线（8,8'）。

64. 发明申请

US20070038125A1 Oct-based imaging method 审中-公开
标题翻译：基于Oct的成像方法
公开(公告)号：US20070038125A1
公开(公告)日：2007-02-15
申请号：US11473412
申请日：2006-06-23
申请人： Martin Kleen , Marcus Pfister , Thomas Redel
发明人： Martin Kleen , Marcus Pfister , Thomas Redel
IPC分类号： A61B6/00
CPC分类号： A61B5/6852 , A61B5/0066 , A61K49/1818 , B82Y5/00 , G01B9/02091 , H01L2924/0002 , H01L2924/00
摘要： The present invention relates to an imaging method with an OCT catheter for visualizing molecular functional processes in vulnerable plaques of a blood vessel of the blood vessel system of a patient, with OCT images of the contrast medium-marked vulnerable plaque being generated during continuously controlled movement of the light-emitting and light-absorbing OCT catheter head along the vulnerable plaque after the intravascular injection of a contrast medium into the blood vessel system and after the intravascular insertion of an imaging OCT catheter into the blood vessel comprising the vulnerable plaque.
摘要翻译：本发明涉及一种具有OCT导管的成像方法，用于在患者的血管系统的血管的易损斑块中可视化分子功能过程，其中在持续控制运动期间产生造影剂标记的易损斑块的OCT图像的血管内注射造影剂进入血管系统之后和血管内插入成像OCT导管进入包含易损斑块的血管中的易发生斑块的发光和光吸收OCT导管头。

65. 发明授权

US07156554B2 Method of compensating for image faults in an x-ray image recording 有权
标题翻译：补偿X射线图像记录中的图像故障的方法
公开(公告)号：US07156554B2
公开(公告)日：2007-01-02
申请号：US11144998
申请日：2005-06-03
申请人： Marcus Pfister
发明人： Marcus Pfister
IPC分类号： G21K1/02
CPC分类号： G06T5/008 , A61B6/5258 , G06T2207/10116 , G06T2207/30004
摘要： Method for compensating for image faults in a digital image recording which has been created by an x-ray system consisting of a radiographic source, an anti-scatter grid and a digital x-ray detector such as an image amplifier or a solid-state image detector, said image faults resulting from decentering, defocusing or defects in the anti-scatter grid or by the Heel effect and causing an intensity reduction of the primary radiation falling on the x-ray detector, characterized in that the actual reduction in intensity is measured through the anti-scatter grid and correction parameters are determined based on the measured values recorded which are then used to correct the x-ray image recording.
摘要翻译：用于补偿由由射线照相源，防散射栅格和数字X射线检测器（诸如图像放大器或固态图像）组成的x射线系统产生的数字图像记录中的图像故障的方法检测器，所述图像故障是由于散焦网格中的偏心，散焦或缺陷引起的，或者由鞋跟效应引起的，并且引起落在X射线检测器上的主要辐射的强度降低，其特征在于测量强度的实际降低通过反散射网格和校正参数是基于记录的测量值来确定的，然后将其用于校正x射线图像记录。

66. 发明申请

US20060285738A1 Method and device for marking three-dimensional structures on two-dimensional projection images 有权
标题翻译：用于在二维投影图像上标记三维结构的方法和装置
公开(公告)号：US20060285738A1
公开(公告)日：2006-12-21
申请号：US11453623
申请日：2006-06-15
申请人： Jan Boese , Andreas Meyer , Marcus Pfister , Norbert Rahn
发明人： Jan Boese , Andreas Meyer , Marcus Pfister , Norbert Rahn
IPC分类号： G06K9/00
CPC分类号： G03B42/026 , A61B6/02 , A61B6/4441 , A61B6/466 , A61B6/469 , A61B6/481 , A61B6/503 , A61B6/504 , A61B6/541 , A61B34/20 , A61B90/37 , A61B2017/00703 , A61B2090/364 , A61B2090/376 , G03B42/021
摘要： The invention relates to a method and a device for marking three-dimensional structures on two-dimensional projection images of an object, with which a position marker is determined on two projection images of the object recorded from different projection directions, from which the position of the position marker in the three-dimensional space is calculated so that further, subsequently recorded projection images can be displayed superimposed by the position marker.
摘要翻译：本发明涉及一种用于标记物体的二维投影图像上的三维结构的方法和装置，利用该方法和装置在从不同投影方向记录的物体的两个投影图像上确定位置标记，计算三维空间中的位置标记，使得随后记录的投影图像可以通过位置标记叠加显示。

67. 发明申请

US20060274888A1 Medical imaging system with a part which can be moved about a patient and a collision protection method 有权
标题翻译：具有可以围绕患者移动的部分的医疗成像系统和碰撞保护方法
公开(公告)号：US20060274888A1
公开(公告)日：2006-12-07
申请号：US11437090
申请日：2006-05-19
申请人： Philipp Bernhardt , Jan Boese , Marcus Pfister , Norbert Rahn
发明人： Philipp Bernhardt , Jan Boese , Marcus Pfister , Norbert Rahn
IPC分类号： H05G1/54
CPC分类号： A61B6/102 , G05B19/4061 , G05B2219/45169 , G05B2219/49143
摘要： The invention relates to a medical imaging system as well as a collision protection method for such a system. In this system the movement of a moveable part, e.g. a C-arm, is stopped or slowed down, if the part enters an individual protective zone enclosing the patient. This zone is calculated individually for each patient from the surface of the patient detected by an optical sensor.
摘要翻译：本发明涉及医疗成像系统以及这种系统的碰撞保护方法。在该系统中，可移动部件的运动，例如，如果部件进入包围患者的个人保护区，则停止或减慢C形臂。对于由光学传感器检测到的患者表面的每个患者，该区域被分别计算。

68. 发明申请

US20060239531A1 Device for recording cross-sectional images 有权
标题翻译：用于记录截面图像的装置
公开(公告)号：US20060239531A1
公开(公告)日：2006-10-26
申请号：US11410631
申请日：2006-04-25
申请人： Martin Kleen , Marcus Pfister
发明人： Martin Kleen , Marcus Pfister
IPC分类号： G06K9/00
CPC分类号： A61B5/6852 , A61B5/0066 , A61B5/0073
摘要： In order to improve the quality of cross-sectional images, which have been recorded along a longitudinal axis of a vessel of a body, it is proposed to add successive cross-sectional images to an overall cross-sectional image. Artifacts in the cross-sectional images are hereby weakened and pathological structures to be detected are high-lighted.
摘要翻译：为了提高沿着身体的血管的纵轴记录的横截面图像的质量，建议将连续的横截面图像添加到整个横截面图像。因此，横截面图像中的人造物被削弱，并且待检测的病理结构被高光照射。

69. 发明申请

US20060167357A1 Device for making visible a pathological change in a part of the body labeled with a fluorescent dye 失效
标题翻译：用于使用荧光染料标记的身体的一部分可见病理变化的装置
公开(公告)号：US20060167357A1
公开(公告)日：2006-07-27
申请号：US11330575
申请日：2006-01-12
申请人： Gunter Lauritsch , Marcus Pfister
发明人： Gunter Lauritsch , Marcus Pfister
IPC分类号： A61B6/00
CPC分类号： A61B5/6814 , A61B5/0059 , A61B5/0071 , A61B5/444 , A61B5/445
摘要： The invention relates to a device for making visible a pathological change in a part of a patient's body labeled with a fluorescent dye, the device having: a first selectable light source (11, 17), which emits light in the excitation wavelength range of the fluorescent dye, in order to trigger the emission of light in the emission wavelength range of the fluorescent dye, a second selectable light source, which emits visible light outside the emission wavelength of the fluorescent dye, and a means for selectively switching the first and the second light source on and off.
摘要翻译：本发明涉及一种用于使被标记有荧光染料的患者身体的一部分可见病理变化的装置，所述装置具有：第一可选择光源（11,17），其在所述荧光染料的激发波长范围内发射光荧光染料，为了触发在荧光染料的发射波长范围内的光的发射，第二可选择的光源，其在荧光染料的发射波长之外发射可见光，以及用于选择性地切换第一和第第二光源开关。

70. 发明授权

US11382577B2 Determining stiffness information of a medical instrument 有权
公开(公告)号：US11382577B2
公开(公告)日：2022-07-12
申请号：US15942992
申请日：2018-04-02
申请人： Katharina Breininger , Marcus Pfister
发明人： Katharina Breininger , Marcus Pfister
IPC分类号： A61B6/12 , A61B6/00 , A61B6/03 , G06T7/30
摘要： Methods and systems are provided for determining a stiffness information of a medical instrument used during a minimally invasive interventional procedure in a vascular system of a patient by recording a three-dimensional volume image of the vascular system at least in the intervention region.

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