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61. 发明授权

US06761719B2 Superelastic spinal stabilization system and method 失效
标题翻译：超弹性脊柱稳定系统及方法
公开(公告)号：US06761719B2
公开(公告)日：2004-07-13
申请号：US09960770
申请日：2001-09-21
申请人： Jeff R. Justis , Michael C. Sherman
发明人： Jeff R. Justis , Michael C. Sherman
IPC分类号： A61B1756
CPC分类号： A61B17/7011 , A61B17/70 , A61B17/7059 , A61B17/8042 , A61B2017/00867 , A61F2002/30092 , A61F2002/449 , A61F2210/0014 , Y10S606/91 , Y10S606/911
摘要： A device for stabilizing at least a portion of the spinal column, including a longitudinal member sized to span a distance between at least two vertebral bodies and being at least partially formed of a shape-memory material exhibiting pseudoelastic characteristics at about human body temperature. A number of bone anchors are used to secure the longitudinal member to each of the vertebral bodies. The longitudinal member is reformed from an initial configuration to a different configuration in response to the imposition of stress caused by relative displacement between the vertebral bodies, and recovers toward the initial configuration when the stress is removed to thereby provide flexible stabilization to the spinal column. During reformation of the longitudinal member, at least a portion of the shape-memory material transforms into stress-induced martensite. In a particular aspect of the invention, the longitudinal member is a plate having a central portion at least partially formed of the shape-memory material, and a pair of connection portions disposed at opposite ends of the central portion for connection to each of the vertebral bodies. The central portion of the plate defines a number of alternating ridges and grooves along a length thereof having an initial amplitude corresponding to the initial configuration and a different amplitude corresponding to the different configuration.
摘要翻译：一种用于稳定脊柱的至少一部分的装置，包括纵向构件，所述纵向构件的尺寸设置为跨越至少两个椎体之间的距离，并且至少部分地由在大约人体温度下显示假弹性特征的形状记忆材料形成。使用许多骨锚来将纵向构件固定到每个椎体。响应于施加由椎体之间的相对位移引起的应力而将纵向构件从初始构型重新形成为不同的构造，并且当应力被移除时朝向初始构型恢复，从而向脊柱提供柔性稳定性。在纵向构件的改造期间，形状记忆材料的至少一部分转变为应力诱导马氏体。在本发明的特定方面中，纵向构件是具有至少部分地由形状记忆材料形成的中心部分的板，以及设置在中心部分的相对端部处的一对连接部分，用于连接到每个脊椎身体。板的中心部分沿着其长度限定了多个交替的脊和槽，其具有对应于初始构型的初始幅度和对应于不同配置的不同幅度。

62. 发明授权

US06605090B1 Non-metallic implant devices and intra-operative methods for assembly and fixation 有权
标题翻译：非金属植入装置和术中用于组装和固定的方法
公开(公告)号：US06605090B1
公开(公告)日：2003-08-12
申请号：US09696128
申请日：2000-10-25
申请人： Hai H. Trieu , Jeff R. Justis , Troy D. Drewry , Michael C. Sherman , Bradley J. Coates , Bradley T. Estes
发明人： Hai H. Trieu , Jeff R. Justis , Troy D. Drewry , Michael C. Sherman , Bradley J. Coates , Bradley T. Estes
IPC分类号： A61B1756
CPC分类号： A61B17/8042 , A61B17/7059 , A61B17/8052 , A61B17/8085 , A61B17/866 , A61B2017/00004 , A61F2/0811
摘要： This invention relates to orthopedic implants and to methods of treating bone defects. More specifically, but not exclusively, the present invention is directed to non-metallic implants and to methods for intra-operative assembly and fixation of orthopedic implants to facilitate medical treatment. The non-metallic implant assembly can be secured to underlying tissue by a fastener, such as a bone screw, that is capable of swelling on contact with fluid in the underlying tissue. Alternatively, the non-metallic implant assembly can be assembled intra-operatively using a fastener that is adhesively bonded to a bone plate or the bone plate can be deformed using heat, force or solvents to inhibit withdrawal of the fastener. In preferred embodiments, both the fastener and the bone plate are formed of biodegradable material.
摘要翻译：本发明涉及矫形植入物和治疗骨缺损的方法。更具体地但非唯一地，本发明涉及非金属植入物以及用于手术中组装和固定矫形植入物以方便医疗的方法。非金属植入物组件可以通过紧固件（例如骨螺钉）固定到下面的组织上，该紧固件能够在与下面的组织中的流体接触时膨胀。或者，非金属植入物组件可以使用粘合剂粘合到骨板上的紧固件在手术中组装，或者骨板可以使用热，力或溶剂变形以阻止紧固件的拉出。在优选实施例中，紧固件和骨板都是由可生物降解的材料形成的。

63. 发明授权

US06254602B1 Advanced coupling device using shape-memory technology 有权
标题翻译：先进的耦合器件采用形状记忆技术
公开(公告)号：US06254602B1
公开(公告)日：2001-07-03
申请号：US09408197
申请日：1999-09-29
申请人： Jeff R. Justis
发明人： Jeff R. Justis
IPC分类号： A61B1756
CPC分类号： A61B17/7037 , A61B17/7032 , A61B17/7035 , A61B2017/00867 , F16B1/0014 , Y10S606/911
摘要： An advanced coupling device using shape-memory technology. The coupling device includes a coupling element defining a longitudinal passage extending therethrough, the passage bounded by a side wall having a first end and an opposing second end, the side wall defining a first slot extending from the first end toward the second end, and a second slot extending from the second end toward the first end, and wherein a portion of the second slot is positioned proximately adjacent and longitudinally overlapping a portion of the first slot. The device further includes a compression element at least partially formed of a shape-memory material and being disposed about at least a portion of the coupling element. The compression element has a configuration which contracts about the coupling element and compresses the side wall against a member disposed within the passage to limit movement of the member relative to the coupling element.
摘要翻译：一种使用形状记忆技术的先进的耦合装置。联接装置包括限定通过其延伸穿过的纵向通道的联接元件，该通道由具有第一端和相对的第二端的侧壁限定，该侧壁限定从第一端向第二端延伸的第一狭槽，以及所述第二槽从所述第二端朝向所述第一端延伸，并且其中所述第二槽的一部分定位成邻近所述第一槽的一部分并且纵向重叠。该装置还包括至少部分地由形状记忆材料形成并围绕联接元件的至少一部分设置的压缩元件。压缩元件具有围绕联接元件收缩并且将侧壁压靠在设置在通道内的构件上以限制构件相对于联接元件的移动的构造。

64. 发明授权

US06210413B1 Connecting apparatus using shape-memory technology 失效
标题翻译：使用形状记忆技术的连接装置
公开(公告)号：US06210413B1
公开(公告)日：2001-04-03
申请号：US09408364
申请日：1999-09-29
申请人： Jeff R. Justis , Michael C. Sherman
发明人： Jeff R. Justis , Michael C. Sherman
IPC分类号： A61B1770
CPC分类号： A61B17/7041 , A61B2017/00867
摘要： An apparatus for connecting two members uses shape-memory technology. The connecting apparatus includes a first module having a connector portion adapted for connection to a first member, and a second module having a connector portion adapted for connection to a second member. Each module has a pair of flanges extending therefrom which are disposed about and overlap a portion of the connector portion of the other module. In one embodiment, a compression member at least partially formed of a shape-memory material is disposed adjacent to the flanges and has a first configuration at one temperature which allows relative movement between the modules, and a second configuration at a different temperature which limits relative movement between the modules. In another embodiment, each pair of flanges is at least partially formed of a shape-memory material and has a first configuration at one temperature which allows relative movement between the modules, and a second configuration at a different temperature which limits relative movement between the modules.
摘要翻译：用于连接两个部件的装置使用形状记忆技术。连接装置包括具有适于连接到第一构件的连接器部分的第一模块和具有适于连接到第二构件的连接器部分的第二模块。每个模块具有从其延伸的一对凸缘，该对法兰围绕另一模块的连接器部分的一部分设置。在一个实施例中，至少部分地由形状记忆材料形成的压缩构件设置成与凸缘相邻，并且在允许模块之间的相对移动的一个温度下具有第一构造，并且在不同温度下具有限制相对的第二构型模块之间的移动。在另一个实施例中，每对法兰至少部分地由形状记忆材料形成，并且在一个温度下具有允许模块之间相对移动的第一构型，以及限制模块之间的相对运动的不同温度的第二构型。

65. 发明授权

US08663328B2 Methods for positioning a load-bearing component of an orthopedic implant device by inserting a malleable device that hardens in vivo 有权
标题翻译：通过插入在体内硬化的可延展装置来定位矫形植入装置的承重部件的方法
公开(公告)号：US08663328B2
公开(公告)日：2014-03-04
申请号：US11643177
申请日：2006-12-21
申请人： Jeff R. Justis , Dimitri Protopsaltis , Hai H. Trieu , Michael C. Sherman
发明人： Jeff R. Justis , Dimitri Protopsaltis , Hai H. Trieu , Michael C. Sherman
IPC分类号： A61F2/44
CPC分类号： A61B17/7032 , A61B17/7013 , A61B17/80 , A61B17/8085 , A61B17/866 , A61B2017/00004 , A61B2017/00831 , A61F2/441 , A61F2/442 , A61F2/4425 , A61F2/4465 , A61F2/447 , A61F2002/30062 , A61F2002/30579 , A61F2002/30583 , A61F2002/30649 , A61F2002/30841 , A61F2002/30884 , A61F2210/0004 , A61F2210/0085
摘要： A device is provided that is non-rigid, i.e., flexible and/or malleable, in a first form, and then transformable after insertion to an in vivo site into a rigid, or hardened, form; a cure-initiating energy is applied to the device; and the device is then positioned in the in vivo site where it hardens to provide a load-bearing function or other structural and/or mechanical function. The device includes a biocompatible sheath and a curable material sealed within the sheath. The curable material is provided in a first form that provides flexibility to the device and is structured to rigidize in a second form after application of a quantity of an initiating energy to the material.
摘要翻译：提供了以第一种形式是非刚性的，即柔性的和/或可延展的装置，然后在插入到体内部位之后可变形为刚性或硬化的形式; 对装置施加固化起始能量; 然后将该装置定位在体内部位，在那里其硬化以提供承载功能或其它结构和/或机械功能。该装置包括生物相容护套和密封在护套内的可固化材料。可固化材料以提供该装置的柔性的第一形式提供，并且被构造成在将一定量的起始能量施加到材料之后以第二形式刚性化。

66. 发明授权

US08632524B2 Injectable biocompatible material delivery system 有权
标题翻译：注射生物相容材料输送系统
公开(公告)号：US08632524B2
公开(公告)日：2014-01-21
申请号：US11471993
申请日：2006-06-21
申请人： Hai H. Trieu , Jeff R. Justis , Michael C. Sherman , Dimitri K. Protopsaltis
发明人： Hai H. Trieu , Jeff R. Justis , Michael C. Sherman , Dimitri K. Protopsaltis
IPC分类号： A61K9/22 , A61F2/28
CPC分类号： A61F2/4601 , A61B17/7098 , A61B17/8836 , A61F2002/30583 , A61F2002/4688 , A61F2002/4696 , A61F2210/0085 , A61M2210/1003
摘要： An injectable biocompatible material delivery system is disclosed and can include an injector and a material delivery cannula that can be in fluid communication with the injector. Further, the injectable biocompatible material delivery system can include a light source that can be configured to emit light to at least a portion of the injector, at least a portion of the material delivery cannula, or a combination thereof. Further, the light source can be configured to activate an injectable biocompatible material as it moves through the system.
摘要翻译：公开了可注射的生物相容性材料输送系统，并且可以包括可以与注射器流体连通的注射器和材料输送套管。此外，可注射的生物相容性材料输送系统可以包括光源，其可被配置为向喷射器的至少一部分，材料输送套管的至少一部分或其组合发光。此外，光源可以被配置为在可注射的生物相容性材料移动通过系统时激活。

67. 发明授权

US08211149B2 Elongated members with expansion chambers for treating bony members 有权
标题翻译：细长的成员与膨胀室治疗骨骼成员
公开(公告)号：US08211149B2
公开(公告)日：2012-07-03
申请号：US12119003
申请日：2008-05-12
申请人： Jeff R. Justis
发明人： Jeff R. Justis
IPC分类号： A61B17/70
CPC分类号： A61B17/7017 , A61B17/7032 , A61B2017/00212 , A61B2017/00539
摘要： The present application is directed to devices with expandable lengths for treating bony members. The device may include an elongated member with two sections that are movable relative to each other. An expansion chamber may be positioned between the first and second sections. A pump may move fluid from a reservoir and through a conduit into the expansion chamber. The expansion chamber expands upon receiving the fluid to cause the first and second sections to move apart and increase the length of the elongated member. The device may include multiple expansion chambers along the length, and the elongated member may include multiple sections.
摘要翻译：本申请涉及具有用于治疗骨骼成员的可扩展长度的装置。该装置可以包括具有可相对于彼此移动的两个部分的细长构件。膨胀室可以位于第一和第二部分之间。泵可以将流体从储存器移动并且通过导管移动到膨胀室中。膨胀室在接收流体时膨胀，以使第一和第二部分分开并增加细长构件的长度。该装置可以包括沿着该长度的多个膨胀室，并且细长构件可以包括多个部分。

68. 发明申请

US20120095417A1 Surgical Delivery Instrument and Method 有权
标题翻译：手术输送仪器及方法
公开(公告)号：US20120095417A1
公开(公告)日：2012-04-19
申请号：US12906608
申请日：2010-10-18
申请人： Jeff R. Justis
发明人： Jeff R. Justis
IPC分类号： A61M5/32 , A61B17/00
CPC分类号： A61B17/8897 , A61B17/1604 , A61B2090/036
摘要： A surgical instrument includes a needle extending between a proximal end and a distal end. The needle defines a longitudinal axis. The needle includes an elongated cavity that defines an opening disposed proximal to the distal end. A wire extends between a proximal end and a distal end configured for fixation with tissue. The wire is configured for movable disposal within the cavity. The distal end of the wire includes a retainer configured to prevent advancement of the retainer within the tissue. Methods of use are disclosed.
摘要翻译：手术器械包括在近端和远端之间延伸的针。针限定纵向轴线。针包括细长腔，其限定靠近远端设置的开口。电线在构造成用于固定组织的近端和远端之间延伸。线被配置为在腔内可移动处理。线的远端包括保持器，该保持器构造成防止保持器在组织内的前进。公开了使用方法。

69. 发明授权

US08057519B2 Multi-axial screw assembly 有权
标题翻译：多轴螺丝总成
公开(公告)号：US08057519B2
公开(公告)日：2011-11-15
申请号：US12038572
申请日：2008-02-27
申请人： Jeff R Justis , Fred J. Molz, IV , James M Mirda , Rodney R Ballard , Robert A Farris , Jason M May
发明人： Jeff R Justis , Fred J. Molz, IV , James M Mirda , Rodney R Ballard , Robert A Farris , Jason M May
IPC分类号： A61B17/70
CPC分类号： A61B17/7032 , A61B17/7001 , A61B17/7035 , A61B17/7037 , A61B17/7044 , A61B17/7059
摘要： The present application is directed to multi-axial screw assemblies to connect a longitudinal member to a vertebral member. In one embodiment, the multi-axial screw assembly includes a screw comprising a threaded shank and an enlarged head. The assembly may also include a body with an upper channel sized to receive the longitudinal member, a lower chamber to receive the head. The body is constructed to maintain the head in the lower chamber.
摘要翻译：本申请涉及将纵向构件连接到椎骨构件的多轴螺钉组件。在一个实施例中，多轴螺旋组件包括螺钉，其包括螺纹柄和扩大的头部。组件还可以包括具有尺寸设置成容纳纵向构件的上通道的主体，用于接收头部的下腔室。身体被构造成将头部保持在下腔室中。

70. 发明申请

US20110270313A1 Spinal Rods Having Different Flexural Rigidities About Different Axes and Methods of Use 有权
标题翻译：具有不同弯曲刚度的脊柱与不同的轴和使用方法
公开(公告)号：US20110270313A1
公开(公告)日：2011-11-03
申请号：US13181474
申请日：2011-07-12
申请人： Jeff R. Justis , Fred J. Molz, IV , Michael C. Sherman
发明人： Jeff R. Justis , Fred J. Molz, IV , Michael C. Sherman
IPC分类号： A61B17/70
CPC分类号： A61B17/7029 , A61B17/7002 , A61B17/701
摘要： A vertebral rod for stabilizing a patient's spine. The rod may include an elongated body with first and second ends and have an elongated cross-sectional shape with a major axis and a minor axis and a centroid positioned at an intersection of the axes. First and second longitudinal channels may extend through the body. The channels may be spaced apart and contained within the body. The body may have a first flexural rigidity along the major axis and a different second flexural rigidity along the minor axis.
摘要翻译：用于稳定患者脊柱的椎骨杆。杆可以包括具有第一和第二端部的细长主体并且具有长轴和短轴的细长横截面形状，并且心轴位于轴线的交点处。第一和第二纵向通道可延伸穿过主体。通道可以间隔开并容纳在体内。主体可以具有沿着长轴的第一弯曲刚度和沿着短轴的不同的第二弯曲刚度。

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