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61. 发明专利

AU2020353078A1 Small form-factor battery with high power density 未知
公开(公告)号：AU2020353078A1
公开(公告)日：2022-04-14
申请号：AU2020353078
申请日：2020-09-24
申请人： INCUBE LABS LLC
发明人： IMRAN MIR A , WAHAB RADIA ABDUL , ONG CHANG JIN
IPC分类号： H01M4/06 , H01M4/88 , H01M10/613 , H01M50/109 , H01M50/121 , H01M50/153
摘要： A base cell structure includes a containment ring defining an opening extending therethrough. An inner wall of the containment ring defines a perimeter limit of a base cell volume. The containment ring provides a liquid-impermeable casing at the perimeter limit. A first set of active particles is disposed in the base cell volume of a first base cell structure to form an anode cell. A second set of active particles is disposed in the base cell volume of a second base cell structure to form a cathode cell. The anode cell and the cathode cell are assembled together with a separator disposed between. Two electrode plates are disposed on the assembly, one adjacent to the anode cell and one adjacent to the cathode cell, to respectively provide an anode electrode plate and a cathode electrode plate which are disposed on opposite outer sides of the assembly.

62. 发明专利

ES2884177T3 Catéteres uretrales para facilitar la introducción en las vías urinarias 未知
公开(公告)号：ES2884177T3
公开(公告)日：2021-12-10
申请号：ES17760859
申请日：2017-03-02
申请人： INCUBE LABS LLC
发明人： IMRAN MIR
IPC分类号： A61M25/01 , A61N1/36
摘要： Un catéter de drenaje urinario (10) que comprende: un cuerpo de catéter flexible alargado (12) conformado y configurado para permitir el avance hasta el interior de la vejiga de un paciente a través de la uretra del paciente; el cuerpo de catéter tiene un extremo distal (16) y un extremo proximal (14) y un lumen de drenaje (18) que se extiende desde el extremo distal al extremo proximal del cuerpo de catéter y que proporciona una vía de drenaje de orina cuando el extremo distal del catéter está colocado en la vejiga del paciente; al menos un anclaje desplegable (22) colocado cerca del extremo distal del cuerpo de catéter, estando el anclaje configurado para mantener el catéter en su sitio cuando el anclaje se despliega en la vejiga; y al menos un electrodo de estimulación del nervio (43) colocado cerca del extremo distal del cuerpo de catéter, el electrodo de estimulación del nervio configurado y colocado sobre el cuerpo de catéter para suministrar una corriente de alta frecuencia al nervio pudendo del paciente para relajar el esfínter urinario del paciente a medida que el extremo distal del cuerpo de catéter se acerca al esfínter urinario, de modo que el cuerpo de catéter pueda avanzar a través del esfínter urinario hasta el interior de la vejiga con una fuerza de resistencia reducida.

63. 发明专利

AU2020270117A1 Anchor system for retaining a device in tissue 未知
公开(公告)号：AU2020270117A1
公开(公告)日：2021-11-18
申请号：AU2020270117
申请日：2020-05-07
申请人： INCUBE LABS LLC
发明人： FISCHER ELMAR , GAFFNEY ROBERT , GEORGE VARGHESE K , HORLEN KYLE , IMRAN MIR A , NELSON CHARLES GREGORY , SPEHR PAUL
IPC分类号： A61N1/05 , A61B5/02 , A61M25/01 , A61M25/02 , A61M25/04
摘要： A lead device is provided for a medical treatment apparatus, where the lead device includes protruding anchoring mechanisms for anchoring the lead device in tissue. The anchoring mechanism include permanent anchoring mechanisms, or a combination of permanent and dissolvable anchoring mechanisms, to anchor the device in tissue. The anchoring mechanism resists migration of the lead device in at least one or both axial directions.

64. 发明专利

AU2021204010A1 Systems and methods for patient-enabled bladder control 未知
公开(公告)号：AU2021204010A1
公开(公告)日：2021-07-08
申请号：AU2021204010
申请日：2021-06-17
申请人： INCUBE LABS LLC
发明人： IMRAN MIR
IPC分类号： A61N1/00 , A61N1/05 , A61N1/36 , A61N1/372 , A61N1/375 , A61N1/378
摘要： Abstract A system for controlling urination in a patient includes an implantable controller and an external device. The implantable controller includes circuitry and electrodes for stimulating the pudenal nerves in order to control urination. In addition, the implantable controller includes sensors for determining information on bladder fullness and for transmitting such information to an external device which is used for controlling the implanted controller. The external device will display when bladder filling exceeds a safe threshold level, allowing the patient and a caregiver to take appropriate steps to allow the patient to urinate.

65. 发明专利

AU2018334419A1 Iontophoretic systems, kits and methods for transdermal delivery of cosmetic agents 未知
公开(公告)号：AU2018334419A1
公开(公告)日：2020-03-05
申请号：AU2018334419
申请日：2018-09-18
申请人： INCUBE LABS LLC
发明人： IMRAN MIR A
IPC分类号： A61F13/02 , A61K9/06 , A61K9/70 , A61M31/00 , A61M35/00 , A61M37/00 , A61N1/04 , A61N1/18
摘要： Embodiments provide systems for delivering cosmetic agents (CA) into the skin. The system includes a power source and at least two electrode assemblies (EA) which may be attached or otherwise incorporated into a facemask assembly that fits over the users face. Each EA is configured to be held in contact with a facial or other skin layer. Additionally, each EA includes an electrode that is coupled to the power source to receive an output current from the power source. At least one of the EAs in the pair includes a medium that carries a CA, the medium being provided on the at least one electrode assembly to enable the output current to deliver the cosmetic agent into the epidermal dermal or other layer of the skin. Embodiments are particularly useful for delivering CAs into a selected layer of the skin to produce a desired cosmetic effect.

66. 发明专利

AU2019203904A1 Solid drug delivery apparatus, formulations and methods of use 未知
公开(公告)号：AU2019203904A1
公开(公告)日：2019-06-20
申请号：AU2019203904
申请日：2019-06-04
申请人： INCUBE LABS LLC
发明人： IMRAN MIR
IPC分类号： A61M1/00
摘要： SOLID DRUG DELIVERY APPARATUS, FORMULATIONS AND METHODSOFUSE Embodiments provide apparatus and methods for delivering solid form medications such as pellets (100) to various locations in the body. One embodiment provides an apparatus (10) for in vivo delivery of medication pellets (100) comprising a housing (30) including a port (35), a pellet-containing belt disposed in the housing (30), and a mechanism for transferring the pellets (100) from the belt to a delivery site (DS) outside the housing (30). Each pellet (100) contains a dose of drug to treat a medical condition. An elongate member (60) is coupled to the housing (30) and includes a lumen (61) for pellet delivery, a proximal end (62) coupled to the port (35) and a distal end (63) positioned at the DS. The pellet (100) can be delivered to the DS at regular intervals or responsive to a detected biological event. Embodiments of the invention are particularly useful for delivering medication to treat a medical condition over an extended period without requiring a patient to take external medication.

67. 发明专利

CA3067021A1 SWALLOWABLE CAPSULE, SYSTEM AND METHOD FOR MEASURING GASTRIC EMPTYING PARAMETERS 未知
公开(公告)号：CA3067021A1
公开(公告)日：2018-12-20
申请号：CA3067021
申请日：2018-06-12
申请人： INCUBE LABS LLC
发明人： IMRAN MIR
IPC分类号： A61B5/00
摘要： Embodiments provide devices, systems and methods for measuring a gastric emptying (GE) parameter (GEP). Many embodiments provide a swallowable capsule having three electrodes one covered by a coating which remains in the stomach but is degraded in the small intestine (SI). The electrodes are coupled to circuitry such that when the capsule is in the stomach, current flow occurs between the first two electrodes generating a first signal and in the SI current flow occurs between the second and now uncovered third electrode generating a second signal. These two signals can be transmitted and analyzed externally or by an internal controller to determine a GEP e.g., GE time. The patient may wear an external device configured to receive and analyze the signals to determine GE time. Embodiments of the invention may be used to diagnose gastroparesis and provide patients information on when to eat meals or administer insulin after eating.

68. 发明专利

AU2014244437B2 Apparatus, systems and methods for delivery of medication to the brain to treat neurological conditions 未知
公开(公告)号：AU2014244437B2
公开(公告)日：2018-11-08
申请号：AU2014244437
申请日：2014-03-12
申请人： INCUBE LABS LLC
发明人： IMRAN MIR , MORGAN PHILLIP , TRANCHINA BEN , SPHER PAUL , HORLEN KYLE
IPC分类号： A61M31/00
摘要： Various embodiments provide an apparatus, system method for treating neurological conditions by delivering solid form medication to the ventricles or other areas of the brain. Particular embodiments provide an apparatus and method for treating epilepsy and other neurological conditions by delivering solid form medication to ventricles in the brain wherein the medication is contained in a diffusion chamber so as to allow the medication to dissolve in the cerebrospinal fluid of the brain and then diffuse out of the diffusion chamber to be delivered to the ventricles and brain tissue. In one or more embodiments, portions of apparatus have sufficient flexibility to conform to the shape of the ventricles of the brain when advanced into them and/or to not cause deformation of the ventricle sufficient to cause a significant physiologic effect.

69. 发明专利

AU2016203077B2 Swallowable capsule and method for stimulating incretin production within the intestinal tract 未知
公开(公告)号：AU2016203077B2
公开(公告)日：2017-12-07
申请号：AU2016203077
申请日：2016-05-12
申请人： INCUBE LABS LLC
发明人： IMRAN MIR , HASHIM MIR , ARNSDORF EMILY
IPC分类号： A61K38/00
摘要： SWALLOWABLE CAPSULE AND METHOD FOR STIMULATING INCRETIN PRODUCTION WITHIN THE INTESTINAL TRACT Embodiments of the invention provide apparatus and methods for stimulating L cells in the intestinal tract to produce incretins for the treatment of conditions including diabetes and obesity. Many embodiments provide a method and apparatus for the treatment of diabetes by electrically stimulating L-cells to secrete incretins to stimulate or otherwise modulate the production of insulin. Particular embodiments provide a swallowable capsule for stimulating L-cells in the intestinal tract as a capsule moves through the tract. The capsule can include two or more electrodes for providing electrical stimulation to L-cells, a power source for powering one or more components of the capsule, a sensor for sensing the location of the capsule in the intestinal tract; a controller and a waveform generator for generating the electrical signals emitted by the electrodes to stimulate the L-cells to secrete incretins such as GLP- 1 to stimulate insulin production for glucose regulation of diabetic conditions. - 21 -

70. 发明专利

AU2016203406B2 IONTOPHORETIC SYSTEM FOR TRANSDERMAL DELIVERY OF ACTIVE AGENTS FOR THERAPEUTIC AND MEDICINAL PURPOSES 未知
公开(公告)号：AU2016203406B2
公开(公告)日：2017-11-23
申请号：AU2016203406
申请日：2016-05-25
申请人： INCUBE LABS LLC
发明人： IMRAN MIR
IPC分类号： A61N1/30 , A61N1/04 , A61N1/18
摘要： An embodiment of a system includes a power source and at least two electrode assembles which may be arranged in a pair. The power source has an output current that alternates between a maximum and a minimum current value. Each electrode assembly is configured to be held in contact with a skin layer of a user. Additionally, each electrode assembly includes an electrode that is coupled to the power source to receive the output current from the power source. At least one of the electrode assemblies in the pair includes a medium that carries an active agent having a charge, the medium being provided on the at least one electrode assembly to enable the output current to repel the active agent into the skin layer for a duration in which the output current has a polarity that is the same as a polarity of the active agent. WO 2010/093546 PCT/US2010/023112 124 122 + +1 Skin Layer 210 233 212 224 22 4++ + +++ 21 ++ ++ +++ Double Point Distribution (t1, t3..tn) i(t2, t4..tn+l 312 310 -- -- -- -n_) - Single Point Distribution Int. 345Skin 322 nput 342 F G Sensor 344 - --- -- - - =Timer 346'

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