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61. 发明申请

WO2008091933A1 ORAL CARE IMPLEMENT HOUSING AN ORAL CARE AGENT 审中-公开
标题翻译：口腔护理实施房屋口腔护理代理
公开(公告)号：WO2008091933A1
公开(公告)日：2008-07-31
申请号：PCT/US2008/051776
申请日：2008-01-23
申请人： COLGATE-PALMOLIVE COMPANY , GATZEMEYER, John, J. , RUSSELL, Bruce, M. , WAGUESPACK, Kenneth , BOYD, Thomas, J.
发明人： GATZEMEYER, John, J. , RUSSELL, Bruce, M. , WAGUESPACK, Kenneth , BOYD, Thomas, J.
IPC分类号： A46B11/00 , A46B15/00
CPC分类号： A46B11/001 , A46B11/0068 , A46B2200/1066
摘要： An oral care implement may include a tufted insert and a base configured to define a cavity for housing an active insert. The active insert may comprise an active agent. The head of the oral care implement may be configured so that the active insert can be in fluid communication with a membrane or an aperture.
摘要翻译：口腔护理器具可以包括簇绒插入物和构造成限定用于容纳活动插入物的空腔的底座。活性插入物可以包含活性剂。口腔护理器具的头部可以被配置成使得活动插入件可以与膜或孔流体连通。

62. 发明申请

WO2007130841A2 ORAL COMPOSITIONS COMPRISING SILOXANE POLYMERS 审中-公开
标题翻译：包含硅氧烷聚合物的口腔组合物
公开(公告)号：WO2007130841A2
公开(公告)日：2007-11-15
申请号：PCT/US2007067495
申请日：2007-04-26
申请人： COLGATE PALMOLIVE CO , BOYD THOMAS J
发明人： BOYD THOMAS J
IPC分类号： A61Q11/00 , A61K8/896
CPC分类号： A61Q11/00 , A61K8/896 , B65D83/205
摘要： Oral compositions are provided that comprise an active ingredient comprising a siioxane polymer having at least one hydrophilic region. The oral care composition comprises a siioxane polymer having a phosphorus-containing moiety. A source of fluoride ions and/ or other oral care actives can be included in the oral care composition. Methods of making and using the oral compositions are also provided.
摘要翻译：提供口服组合物，其包含含有至少一个亲水区的硅氧烷聚合物的活性成分。口腔护理组合物包含具有含磷部分的硅氧烷聚合物。氟离子和/或其它口腔护理活性物质的来源可以包括在口腔护理组合物中。还提供了制备和使用口腔组合物的方法。

63. 发明申请

WO2007008908A1 ORAL CARE IMPLEMENT HAVING RESERVOIR FOR DISPENSING ACTIVE AGENT 审中-公开
标题翻译：具有用于分配活性剂的储存器的口腔护理实施
公开(公告)号：WO2007008908A1
公开(公告)日：2007-01-18
申请号：PCT/US2006/026904
申请日：2006-07-11
申请人： COLGATE-PALMOLIVE COMPANY , CAI, Heng , BOYD, Thomas
发明人： CAI, Heng , BOYD, Thomas
IPC分类号： A46B11/00
CPC分类号： A46B15/0002 , A46B11/0058 , A46B11/0062 , A46B11/0065 , A46B15/0034 , A46B2200/1066 , A61K8/02 , A61K8/22 , A61K8/24 , A61K8/4926 , A61Q11/00
摘要： An oral care implement includes a reservoir containing at least one active agent. The implement has an activator for activating a delivery device, which delivers a predetermined amount of an active agent to one or more outlets. A wide variety of types of active agents can be administered at appropriate and accurate doses for therapeutic, hygienic and/or other benefits.
摘要翻译：一种口腔护理器具包括含有至少一种活性剂的贮存器。该器具具有用于激活输送装置的激活器，其将预定量的活性剂递送到一个或多个出口。多种类型的活性剂可以以适当且准确的剂量施用，用于治疗，卫生和/或其他益处。

64. 发明申请

WO2006071712A1 ORAL COMPOSITIONS CONTAINING OXIDIZED CAMELLIA 审中-公开
标题翻译：含有氧化斑点的口腔组合物
公开(公告)号：WO2006071712A1
公开(公告)日：2006-07-06
申请号：PCT/US2005/046514
申请日：2005-12-21
申请人： COLGATE-PALMOLIVE COMPANY , BOYD, Thomas , GAFFAR, Abdul , VISCIO, David
发明人： BOYD, Thomas , GAFFAR, Abdul , VISCIO, David
IPC分类号： A61K8/00 , A61K36/82 , A61K47/30 , A61P1/02
CPC分类号： A61K8/8164 , A61K8/97 , A61K36/82 , A61Q11/00 , A61K2300/00
摘要： Oral composition comprising a Camellia extract of semi-oxidized tissue from a member of the genus Camellia and an enhancing agent.
摘要翻译：包含来自山茶属的半氧化组织的山茶提取物和增强剂的口腔组合物。

65. 发明申请

WO2005117820A1 METHOD FOR INHIBITING CHEMICAL STAINING OF TEETH 审中-公开
标题翻译：阻止化学品染色的方法
公开(公告)号：WO2005117820A1
公开(公告)日：2005-12-15
申请号：PCT/US2005/019414
申请日：2005-06-02
申请人： COLGATE-PALMOLIVE COMPANY , MILANOVICH, Nebojsa , BOYD, Thomas , PRENCIPE, Michael
发明人： MILANOVICH, Nebojsa , BOYD, Thomas , PRENCIPE, Michael
IPC分类号： A61K7/16
CPC分类号： A61K8/81 , A61K8/22 , A61Q11/00
摘要： A method for inhibiting chemical staining of a dental surface comprises contacting the dental surface, prior to said staining, with an orally acceptable polymer or copolymer comprising a plurality of monomeric groups of formula (I) wherein (a) one of A and A' is hydrogen and the other is a moiety (X) n (R) m , (b) n in individual such moieties is independently 0 or 1, (c) linking groups X if present independently comprise an oxygen, sulfur, nitrogen, phosphorus or silicon atom, (d) where n is 0, m is 1, and where n is 1, m is independently an integer from 1 to 3 as determined by X, (e) terminal groups R are independently hydrogen or C 1-18 organic radicals, and (f) M and M' are independently selected from hydrogen, alkali metal and ammonium; said polymer or copolymer having an average molecular weight of at least about 1,000.
摘要翻译：用于抑制牙齿表面的化学染色的方法包括在所述染色之前使牙齿表面与包含多个式（I）的单体基团的口腔可接受的聚合物或共聚物接触，其中（a）A和A'之一为氢和另一个是单独的这样的部分中的部分（X）n（R）m，（b）n独立地为0或1，（c）连接基团X（如果存在）独立地包括氧，硫，氮，磷或硅原子，（d）其中n为0，m为1，n为1，m独立地为1至3的整数，由X确定，（e）端基R独立地为氢或C1-18有机基，和（f）M和M'独立地选自氢，碱金属和铵; 所述聚合物或共聚物的平均分子量至少约为1,000。

66. 发明申请

WO2004082916A3 ROTARY INJECTION MOLDING APPARATUS AND METHOD FOR USE CROSS-REFERENCE TO RELATED APPLICATIONS 审中-公开
标题翻译：旋转注射成型装置及其使用方法相关申请的交叉引用
公开(公告)号：WO2004082916A3
公开(公告)日：2005-02-03
申请号：PCT/US2004008326
申请日：2004-03-17
申请人： MFG TECHNOLOGIES INTERNAT CORP , BOYD KATHY , BOYD THOMAS J
发明人： BOYD KATHY , BOYD THOMAS J
IPC分类号： B29C45/06 , B29C45/14 , B29C45/42 , B29C45/54 , B29C45/00
CPC分类号： B29C45/06 , B29C45/14008 , B29C45/42 , B29C45/54 , B29C2045/425 , B29K2021/00
摘要： A rotary injection molding apparatus [10] and method for manufacturing products containing elastomeric material within multi-section single cavity molds [30]. The apparatus includes a modular frame [20] supporting an injection molding operation station [40] having an injector assembly [48] with a pressure sensitive nozzle assembly [50, 51]. The injector assembly [48] is engaged with an extruder assembly [46] at a check valve assembly [44]. A mold servicer assembly [42] is provided for assembly and disassembly of multi-section single cavity molds. A robotic arm assembly [70] is supported on the modular frame and positioned for inserting and removing products or product components from disassembled molds. Finally; a rotating table [22] is provided on the frame which has a plurality of work station positions [24] supporting clamping assemblies [28] for clamping single cavity molds [30] around the periphery of the rotating table [22].
摘要翻译：一种旋转注射成型装置[10]，以及在多段单腔模具中制造含有弹性体材料的产品的方法[30]。该装置包括支撑具有压敏喷嘴组件[50,51]的注射器组件[48]的注射成型操作站[40]的模块化框架20。注射器组件[48]在止回阀组件[44]处与挤出机组件[46]接合。提供了一种模具维修组件[42]，用于组装和拆卸多段单腔模具。机械手臂组件[70]支撑在模块化框架上，并定位成用于从拆卸的模具中插入和移除产品或产品组件。最后; 在框架上设置有一个旋转台[22]，其具有多个工作站位置[24]，支撑夹紧组件[28]，用于围绕旋转工作台[22]的周边夹持单腔模具30。

67. 发明申请

WO2005000261A1 MOUTH RINSE COMPOSITIONS CONTAINING N-ACYL-ARGININE ALKYL ESTER SALTS 审中-公开
标题翻译：含有N-亚氨基阿尔茨伯特酸盐盐的口感组合物
公开(公告)号：WO2005000261A1
公开(公告)日：2005-01-06
申请号：PCT/US2004/020192
申请日：2004-06-23
申请人： COLGATE-PALMOLIVE COMPANY , BOYD, Thomas, J. , GAFFAR, Abdul , VISCIO, David, B.
发明人： BOYD, Thomas, J. , GAFFAR, Abdul , VISCIO, David, B.
IPC分类号： A61K7/16
CPC分类号： A61Q11/00 , A61K8/42
摘要： A stable aqueous antiplaque oral composition containing (a) an antibacterial ester compound having the formula (I) where R 1 is an alkyl chain of 1 to 8 carbon atoms, and R 2 is an alkyl chain of 6 to 30 carbon atoms and X is an anion.(b) a stabilizing surfactant; and (c) a humectant. Methods of making the oral composition are also provided.
摘要翻译：一种稳定的抗水性抗菌素口服组合物，其含有（a）具有式（I）的抗菌酯化合物，其中R 1是具有1至8个碳原子的烷基链，R 2是是6〜30个碳原子的烷基链，X是阴离子。（b）稳定表面活性剂; 和（c）保湿剂。还提供了制备口腔组合物的方法。

68. 发明申请

WO2004091665A1 COMBINATION THERAPY FOR CONSTIPATION COMPRISING A LAXATIVE AND A PERIPHERAL OPIOID ANTAGONIST 审中-公开
标题翻译：用于组合包含一个外部和外围的阿片样物质拮抗剂的组合治疗
公开(公告)号：WO2004091665A1
公开(公告)日：2004-10-28
申请号：PCT/US2004/010998
申请日：2004-04-08
申请人： PROGENICS PHARMACEUTICALS, INC. , SANGHVI, Suketu, P. , BOYD, Thomas, A. , MADDON, Paul, J.
发明人： SANGHVI, Suketu, P. , BOYD, Thomas, A. , MADDON, Paul, J.
IPC分类号： A61K45/06
CPC分类号： A61K9/2846 , A61K9/0031 , A61K9/02 , A61K9/2009 , A61K9/2013 , A61K9/2054 , A61K31/485 , A61K45/06 , A61K2300/00
摘要： Methods for treating constipation are provided. The methods include administration of peripheral opioid antagonists in combination with laxatives and/or stool softeners. Patients treatable by the invention include those refractory to conventional laxative and stool softener therapy.
摘要翻译：提供治疗便秘的方法。所述方法包括与轻泻剂和/或粪便软化剂组合施用外周阿片样物质拮抗剂。可通过本发明治疗的患者包括对常规泻药和大便软化剂治疗难治的患者。

69. 发明申请

WO2004091623A1 PHARMACEUTICAL FORMULATIONS CONTAINING METHYLNALTREXONE 审中-公开
标题翻译：含有甲基四氢叶酸的药物制剂
公开(公告)号：WO2004091623A1
公开(公告)日：2004-10-28
申请号：PCT/US2004/010997
申请日：2004-04-08
申请人： PROGENICS PHARMACEUTICALS. INC. , SANGHVI, Suketu, P. , BOYD, Thomas, A.
发明人： SANGHVI, Suketu, P. , BOYD, Thomas, A.
IPC分类号： A61K31/485
CPC分类号： A61K47/02 , A61K9/0019 , A61K9/19 , A61K31/047 , A61K31/195 , A61K31/485 , A61K45/06 , A61K47/12 , A61K47/18 , A61K47/183 , A61K2300/00
摘要： Stable pharmaceutical compositions useful for administering methylnaltrexone are described, as are methods for making the same. Kits, including these pharmaceutical compositions, also are provided.
摘要翻译：描述了用于施用甲基纳曲酮的稳定的药物组合物，以及制备它们的方法。还提供了包括这些药物组合物的试剂盒。

70. 发明申请

WO2012087280A2 GELATIN ENCAPSULATED ORAL CARE COMPOSITION CONTAINING HYDROPHILIC ACTIVE, HYDROPHOBIC STRUCTURING AGENT AND OIL CARRIER 审中-公开
标题翻译：含有亲水性活性疏水结构剂和油性载体的明胶包封口腔护理组合物
公开(公告)号：WO2012087280A2
公开(公告)日：2012-06-28
申请号：PCT/US2010061315
申请日：2010-12-20
申请人： COLGATE PALMOLIVE CO , ONTUMI DENNIS KEMBERO , BOYD THOMAS JAMES , CHOPRA SUMAN KUMAR , BROWN JAMES RICHARD
发明人： ONTUMI DENNIS KEMBERO , BOYD THOMAS JAMES , CHOPRA SUMAN KUMAR , BROWN JAMES RICHARD
IPC分类号： B66C23/16
CPC分类号： A61K8/11 , A46B11/0003 , A46B2200/1066 , A61K8/31 , A61K8/375 , A61K8/4926 , A61K8/8111 , A61Q11/00
摘要： An encapsulated oral care composition includes: (a) a gelatin capsule; and (b) a oral care composition contained within the capsule, and including: (i) a hydrophilic active; (ii) a hydrophobic structuring agent; and (iii) an oil carrier. The hydrophilic active is preferably cetylpyridinium chloride. The hydrophobic structuring agent is preferably a gelled mineral oil. The oil carrier is preferably a vegetable oil. A method of cleaning teeth includes applying to the teeth the encapsulated oral care composition such that the capsule releases the oral care composition to clean the teeth. A oral care implement includes: a handle; a head mounted to the handle, the head having an outer surface and a plurality of tooth cleaning elements extending outwardly from the outer surface; and the encapsulated oral care composition positioned on the head.
摘要翻译：包封的口腔护理组合物包含：（a）明胶胶囊; 和（b）包含在所述胶囊内的口腔护理组合物，并且包括：（i）亲水活性物; （ii）疏水性结构化剂; 和（iii）石油运输船。亲水活性物质优选氯化十六烷基吡啶鎓。疏水性结构剂优选为凝胶矿物油。油载体优选为植物油。清洁牙齿的方法包括向牙齿施用封装的口腔护理组合物，使得胶囊释放口腔护理组合物以清洁牙齿。口腔护理器具包括：手柄; 安装到所述手柄的头部，所述头部具有外表面和从所述外表面向外延伸的多个牙齿清洁元件; 和位于头部的封装的口腔护理组合物。

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