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61. 发明申请

WO2012177377A4 APPARATUS AND METHOD FOR STABILIZING, IMPROVING MOBILITY, AND CONTROLLING CARTILAGE MATRIX DEGRADATION OF WEIGHT-BEARING ARTICULAR JOINTS 审中-公开
公开(公告)号：WO2012177377A4
公开(公告)日：2012-12-27
申请号：PCT/US2012/040518
申请日：2012-06-01
申请人： MEAGAN MEDICAL, INC. , CARROLL, William J.
发明人： CARROLL, William J.
IPC分类号： A61N1/18 , A61N1/36 , A61N1/04
摘要： An apparatus and method for improving mobility and/or the quality of synovial fluid of an affected articular joint are disclosed, wherein the joint is associated with at least a first muscle group and at least a second muscle group each having an antagonistic relationship for effecting mobility of the joint through a range of motion when recruited by natural neural impulses. The apparatus and method include an electro-medical device configured to apply motor-level electrical stimulation in a multiphasic pattern via at least a first channel and at least a second channel, the multiphasic pattern being programmed into the electro-medical device and corresponding to the sequence of an electromyographic output for the joint; at least two first electrodes connected to the at least first channel of said electro-medical device, the at least two first electrodes being positioned proximate to the at least first muscle group; at least two second electrodes connected to the at least second channel of said electro-medical device, the at least two second electrodes being positioned proximate to the at least second muscle group; and an applicator configured to be worn on the articular segment such that the at least two first electrodes and the at least two second electrodes are disposed between the applicator and the articular segment, the applicator being further configured to reduce compressive forces on at least one compartment of the affected joint.

62. 发明申请

WO2012177377A2 APPARATUS AND METHOD FOR STABILIZING, IMPROVING MOBILITY, AND CONTROLLING CARTILAGE MATRIX DEGRADATION OF WEIGHT-BEARING ARTICULAR JOINTS 审中-公开
标题翻译：装置和方法，用于稳定，改善移动性和控制重量承载接头的卡氏矩阵降级
公开(公告)号：WO2012177377A2
公开(公告)日：2012-12-27
申请号：PCT/US2012040518
申请日：2012-06-01
申请人： MEAGAN MEDICAL INC , CARROLL WILLIAM J
发明人： CARROLL WILLIAM J
IPC分类号： A61N1/18 , A61N1/04 , A61N1/36
CPC分类号： A61N1/36003 , A61N1/0452 , A61N1/0456 , A61N1/0472 , A61N1/0476 , A61N1/326 , A61N1/36014
摘要： An apparatus and method for improving mobility and/or the quality of synovial fluid of an affected articular joint are disclosed, wherein the joint is associated with at least a first muscle group and at least a second muscle group each having an antagonistic relationship for effecting mobility of the joint through a range of motion when recruited by natural neural impulses. The apparatus and method include an electro-medical device configured to apply motor-level electrical stimulation in a multiphasic pattern via at least a first channel and at least a second channel, the multiphasic pattern being programmed into the electro-medical device and corresponding to the sequence of an electromyographic output for the joint; at least two first electrodes connected to the at least first channel of said electro-medical device, the at least two first electrodes being positioned proximate to the at least first muscle group; at least two second electrodes connected to the at least second channel of said electro-medical device, the at least two second electrodes being positioned proximate to the at least second muscle group; and an applicator configured to be worn on the articular segment such that the at least two first electrodes and the at least two second electrodes are disposed between the applicator and the articular segment, the applicator being further configured to reduce compressive forces on at least one compartment of the affected joint.
摘要翻译：公开了一种用于改善受影响的关节关节的滑液的移动性和/或质量的装置和方法，其中所述关节与至少第一肌肉组和至少第二肌肉组相关联，每个具有拮抗关系以影响移动性的关节通过自然神经冲动招募的一系列运动。该装置和方法包括：电医疗装置，被配置为经由至少第一通道和至少第二通道以多相模式施加电动机级电刺激，所述多相模式被编程到所述电疗装置中并且对应于关节肌电图输出顺序; 至少两个第一电极，其连接到所述电 - 医疗装置的所述至少第一通道，所述至少两个第一电极位于所述至少第一肌群附近; 至少两个连接到所述电疗装置的至少第二通道的第二电极，所述至少两个第二电极定位成接近所述至少第二肌群; 以及施用器，其构造成佩戴在所述关节段上，使得所述至少两个第一电极和所述至少两个第二电极设置在所述施用器和所述关节段之间，所述施用器还被构造成减小至少一个隔室受影响的关节。

63. 发明申请

WO2011139623A2 SYSTEM AND METHOD FOR STIMULATING SENSORY NERVES 审中-公开
标题翻译：用于刺激感觉神经的系统和方法
公开(公告)号：WO2011139623A2
公开(公告)日：2011-11-10
申请号：PCT/US2011/033733
申请日：2011-04-25
申请人： MEAGAN MEDICAL, INC. , CARROLL, William, J. , AUNE, JR., Erling Jensen , JOHNSON, Timothy, J. , SCHOUENBORG, Jens Olaf Roe
发明人： CARROLL, William, J. , AUNE, JR., Erling Jensen , JOHNSON, Timothy, J. , SCHOUENBORG, Jens Olaf Roe
IPC分类号： A61N1/36 , A61N1/04
CPC分类号： A61N1/0456 , A61N1/0452 , A61N1/0476 , A61N1/0492 , A61N1/0502 , A61N1/0551 , A61N1/36014 , A61N1/36017 , A61N1/36021
摘要： An electrotherapy system for stimulating sensory nerves within skin tissue includes a electrode carrier, a pulse generator, an array of skin-penetrating electrodes and surface skin electrodes, a pulse conditioning circuit, and a power source. The system administers biphasic pulsed current at the surface skin electrodes and monophasic pulsed current at each skin-penetrating electrode. The skin-penetrating surfaces and skin contact surfaces of the electrotherapy system may be sterilized or may be replaceable for outpatient reusability.
摘要翻译：用于刺激皮肤组织内的感觉神经的电疗系统包括电极载体，脉冲发生器，皮肤穿透电极阵列和表面皮肤电极，脉冲调节电路和电源。该系统在每个皮肤穿透电极处施加表面电极处的双相脉冲电流和单相脉冲电流。电疗系统的皮肤穿透表面和皮肤接触表面可以被灭菌或可以替换为门诊可重用性。

64. 发明申请

WO2004058322A2 APPARATUSES AND METHODS FOR COUPLING PERCUTANEOUS DEVICES TO A PATIENT, AND ASSOCIATED METHODS OF MANUFACTURE 审中-公开
标题翻译：将PERCUTANEOUS设备连接到患者
公开(公告)号：WO2004058322A2
公开(公告)日：2004-07-15
申请号：PCT/US2003/039936
申请日：2003-12-16
申请人： MEAGAN MEDICAL, INC.
发明人： MIAZGA, Jay , LEONARD, Paul, C. , GENAU, Chris
IPC分类号： A61M
CPC分类号： A61N1/0551 , A61N1/08 , A61N1/36017 , A61N1/36021
摘要： Apparatuses and methods for supporting couplers for therapy administration and/or monitoring, and associated methods of manufacturing coupler supports. The apparatus can include a support member configured to rest on a body of a recipient proximate to a coupling area. The support member can include a first coupler location configured to removably carry a first coupler proximate to a first coupling position of the body of the recipient. A second coupler location of the support member is configured to removably carry a second coupler proximate to a second coupling position of the body of the recipient. The first and second coupler locations can be arranged to guide the practitioner to connect the couplers properly to the body. For example, the first coupler location can be positioned closer than the second coupler location to the first coupling position. Accordingly, practitioners can be more likely to connect the first and second couplers to the correct coupling position on the body of the recipient.
摘要翻译：用于支持用于治疗管理和/或监视的耦合器的装置和方法，以及制造耦合器支撑件的相关方法。该装置可以包括配置成靠近接合区域的接收器的主体上的支撑构件。支撑构件可以包括构造成可移除地携带第一联接器的第一联接器位置，该第一联接器邻近接收者的主体（22）的第一联接位置。支撑构件的第二联接器位置构造成可移除地携带靠近接收器的主体（22）的第二联接位置的第二联接器。第一和第二联接器位置可以布置成引导从业者将联接器适当地连接到身体。例如，第一联接器位置可以被定位成比第二联接器位置更靠近第一联接位置。因此，从业者可能更可能将第一和第二耦合器连接到接收者的身体（22）上的正确耦合位置。

65. 发明公开

EP1578484A4 CONTROLLING THE DEPTH OF PERCUTANEOUS APPLICATIONS 审中-公开
标题翻译：深度控制器的经皮应用
公开(公告)号：EP1578484A4
公开(公告)日：2007-05-30
申请号：EP03790509
申请日：2003-12-16
申请人： MEAGAN MEDICAL INC
发明人： MIAZGA JAY , GENAU CHRIS , LEONARD PAUL C , GLINER BRADFORD EVAN
IPC分类号： A61M5/46 , A61M20060101 , A61N1/04 , A61N1/05 , A61N1/08
CPC分类号： A61N1/0551 , A61N1/08 , A61N1/36017 , A61N1/36021 , A61N1/375
摘要： Methods and apparatuses for deploying percutaneous probes. An apparatus in accordance with one embodiment of the invention includes a housing (4) and a percutaneous probe having a sharp end (2) and positioned within the housing (4). The percutaneous probe is movable relative to the housing between a stowed position and at least one of a first deployed position and a second deployed position. The percutaneous probe (1) can project from the housing through aperture (5) by a first distance when in the first deployed position and a second distance greater than the first distance when in the second deployed position. A depth control device can operatively couple to the percutaneous probe and can have a first configuration to allow the percutaneous probe to be moved to the first deployed position and a second configuration to allow the percutaneous probe to be moved to the second deployed position.

66. 发明公开

EP1616596A3 Apparatuses and methods for coupling percutaneous devices to a patient, and associated methods of manufacture 审中-公开
标题翻译：装置和用于经皮装置耦合到患者的方法和制备方法相关联的
公开(公告)号：EP1616596A3
公开(公告)日：2006-04-05
申请号：EP05109312.8
申请日：2003-12-16
申请人： MEAGAN MEDICAL, INC.
发明人： Miazaga, Jay , Leonard, Paul C. , Genau, Chris
IPC分类号： A61N1/05 , A61N1/08 , A61N1/34
CPC分类号： A61N1/0551 , A61N1/08 , A61N1/36017 , A61N1/36021
摘要： An apparatus for supporting couplers for removable coupling to a recipient during at least one of therapy administration and recipient monitoring. The apparatus comprises a support member configured to rest on a body of the recipient, the support member having a first coupler support portion configured to be positioned proximate to a first coupling position of the body of the recipient, and a second coupler support portion configured to be positioned proximate to a second coupling position of the body of the recipient. The first coupler support portion is configured to removably carry a first coupler, and the second coupler support portion is configured to removably carry a second coupler. The support member includes a deformable member positioned at least proximate to the first and second coupler support portions, the deformable member being bendable from a first shape to a second shape and configured to at least generally maintain its shape after being bent.

67. 发明公开

EP1618921A2 Controlling the depth of percutaneous applications 审中-公开
标题翻译： Kontrolle der Eindringtiefe von perkutanen Anwendungen
公开(公告)号：EP1618921A2
公开(公告)日：2006-01-25
申请号：EP05108879.7
申请日：2003-12-16
申请人： MEAGAN MEDICAL, INC.
发明人： Miazaga, Jay , Genau, Chris , Leonard, Paul C , Gliner, Bradfrod Evan
IPC分类号： A61N1/34
CPC分类号： A61N1/0551 , A61N1/08 , A61N1/36017 , A61N1/36021 , A61N1/375
摘要： An apparatus for percutaneous application comprising a housing and a percutaneus probe having a sharp end and being disposed within the housing so as to be movable relative to the housing between a stowed position and a deployed position, with at least part of the probe extending out of the housing at the exit portion when the probe is in the deployed position.
According to an embodiment, the housing has an exit portion and an at least partially light emissive portion positioned proximate to the exit portion. The at least partially light transmissive portion is positioned to allow visual access to the exit portion as the probe moves to the deployed position.
摘要翻译：一种用于经皮应用的装置，包括壳体和具有尖端的经皮探针，并且设置在壳体内，以便能够在收起位置和展开位置之间相对于壳体移动，其中探针的至少一部分延伸出当探头处于展开位置时，出口部分处的壳体。根据实施例，壳体具有出口部分和靠近出口部分定位的至少部分轻的发射部分。至少部分透光部分定位成当探头移动到展开位置时允许视觉上进入出口部分。

68. 发明公开

EP1618920A2 Controlling the depth of percuataneous applications 审中-公开
标题翻译： Kontrolle der Eindringtiefe einer perkutanen Anwendung
公开(公告)号：EP1618920A2
公开(公告)日：2006-01-25
申请号：EP05108878.9
申请日：2003-12-16
申请人： MEAGAN MEDICAL, INC.
发明人： Miazaga, Jay , Genau, Chris , Leonard, Paul C. , Gliner, Bradford Evan
IPC分类号： A61N1/34
CPC分类号： A61N1/0551 , A61N1/08 , A61N1/36017 , A61N1/36021 , A61N1/375
摘要： An apparatus for percutaneous application comprising a housing and a first and a second percutaneous probe. A first probe is positioned within the housing and has a sharp end and a first percutaneous length, and is movable relative to the housing between a first stowed position and a first deployed position. A second probe is positioned in the housing simultaneously with the first probe, and has a sharpened end and a second percutaneous length, and is movable relative to the housing between a second stowed position and a second deployed position.
摘要翻译：一种用于经皮应用的装置，包括壳体和第一和第二经皮探针。第一探针定位在壳体内并且具有尖端和第一经皮长度，并且可在第一收起位置和第一展开位置之间相对于壳体移动。第二探针与第一探针同时定位在壳体中，并且具有尖锐的端部和第二经皮长度，并且可相对于壳体在第二收起位置和第二展开位置之间移动。

69. 发明授权

US09962546B2 Cutaneous field stimulation with disposable and rechargeable components 有权
公开(公告)号：US09962546B2
公开(公告)日：2018-05-08
申请号：US14181004
申请日：2014-02-14
申请人： Meagan Medical, Inc.
发明人： William J. Carroll , Mark Edward Schoening , Patrick Allen Scranton , William Richard Huseby
IPC分类号： A61N1/00 , A61N1/36 , A61N1/04
CPC分类号： A61N1/36021 , A61N1/0456 , A61N1/0476 , A61N1/0492 , A61N1/36014
摘要： A CFS system includes self-adhesive, disposable pads. Each pad is combined with a sealed, cleanable battery/controller pod and then placed on the body where needed. The battery/controller pod preferably has wireless capability, such as Bluetooth® capability. The patient can download an application to a smartphone or similar mobile device to control the pods.

70. 发明授权

US09320902B2 Spinal cord stimulation with interferential current 有权
标题翻译：脊髓刺激与干扰电流
公开(公告)号：US09320902B2
公开(公告)日：2016-04-26
申请号：US14606405
申请日：2015-01-27
申请人： Meagan Medical, Inc.
发明人： William J. Carroll
IPC分类号： A61N1/34 , A61N1/36 , A61N1/05 , A61N1/40
CPC分类号： A61N1/36071 , A61N1/0551 , A61N1/0553 , A61N1/36153 , A61N1/36171 , A61N1/36175 , A61N1/36185 , A61N1/36192 , A61N1/40
摘要： A stimulator and a method for the treatment of intractable pain syndromes by electrical stimulation of the spinal cord is disclosed in which implantable electrodes positioned around a targeted area of the spinal cord transmit an interferential current that has a base medium frequency alternating current between 500 Hz-20 KHz. A digital signal processor generates a sine-wave-like waveform from a pulse generator which after further processing is used to generate at least two circuits for use in producing the beat frequency signal. An effective area of stimulation is controlled by the quantity of electrodes, positioning of the electrodes and electrode cross pattern orientation. Amplitude modulation of electrical circuits created at the electrode placements also augments the effective area of stimulation. The stimulator and method reduce accommodation of the body to the electrical stimulation and provide deeper penetration of the resultant signal.
摘要翻译：公开了一种通过电刺激脊髓治疗难治性疼痛综合征的刺激器和方法，其中位于脊髓的目标区域周围的可植入电极传输干涉电流，所述干扰电流具有500Hz- 20 KHz。数字信号处理器从脉冲发生器产生正弦波状波形，其在进一步处理之后用于产生用于产生拍频信号的至少两个电路。刺激的有效区域由电极的数量，电极的定位和电极交叉图案取向来控制。在电极放置处产生的电路的幅度调制也增加了刺激的有效面积。刺激器和方法减少身体对电刺激的适应并且提供所得到的信号的更深的穿透。

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