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61. 发明授权

US08375956B2 Eye registration system for refractive surgery and associated methods 有权
$Eye registration system for refractive surgery and associated methods$
标题翻译：眼科注射系统用于屈光手术及相关方法
公开(公告)号：US08375956B2
公开(公告)日：2013-02-19
申请号：US12777325
申请日：2010-05-11
申请人： Gary P. Gray , John A. Campin
发明人： Gary P. Gray , John A. Campin
IPC分类号： A61B19/00 , A61B18/18
CPC分类号： A61F9/008 , A61B3/113 , A61B3/152 , A61F9/00804 , A61F2009/00846 , A61F2009/00872
摘要： An orientation method for corrective eye surgery that registers pairs of eye images taken at different times and with the patient in different positions includes retrieving reference digital image data on an eye of the patient, including image data on an extracorneal eye feature. Real-time image data are collected that include image data on the extracorneal eye feature. A combined image is displayed of a superposition of the data sets, and a determination is made as to whether the combined image indicates an adequate registration between them based upon the extracorneal eye feature data in the two data sets. If the registration is not adequate, one of the data sets is manipulated until an adequate registration is achieved. A system is directed to apparatus and software for orienting a corrective program for eye surgery.
摘要翻译：用于矫正眼科手术的定向方法，其将在不同时间拍摄的眼睛图像对与患者在不同位置进行记录，包括在患者的眼睛上检索参考数字图像数据，包括在海外眼睛特征上的图像数据。收集实时图像数据，其中包括海角眼部特征上的图像数据。显示数据集的叠加的组合图像，并且基于两个数据集中的海外眼睛特征数据来确定组合图像是否指示它们之间的适当注册。如果注册不充分，则操作其中一个数据集，直到达到足够的注册。系统针对用于定向用于眼科手术的矫正程序的装置和软件。

62. 发明授权

US07815631B2 Eye registration system for refractive surgery and associated methods 有权
$Eye registration system for refractive surgery and associated methods$
标题翻译：眼科注射系统用于屈光手术及相关方法
公开(公告)号：US07815631B2
公开(公告)日：2010-10-19
申请号：US10999268
申请日：2004-11-30
申请人： Gary P. Gray , John A. Campin
发明人： Gary P. Gray , John A. Campin
IPC分类号： A61B18/18
CPC分类号： A61F9/008 , A61B3/113 , A61B3/152 , A61F9/00804 , A61F2009/00846 , A61F2009/00872
摘要： An orientation method for corrective eye surgery that registers pairs of eye images taken at different times and with the patient in different positions includes retrieving reference digital image data on an eye of the patient, including image data on an extracorneal eye feature. Real-time image data are collected that include image data on the extracorneal eye feature. A combined image is displayed of a superposition of the data sets, and a determination is made as to whether the combined image indicates an adequate registration between them based upon the extracorneal eye feature data in the two data sets. If the registration is not adequate, one of the data sets is manipulated until an adequate registration is achieved. A system is directed to apparatus and software for orienting a corrective program for eye surgery.
摘要翻译：用于矫正眼科手术的定向方法，其将在不同时间拍摄的眼睛图像对与患者在不同位置进行记录，包括在患者的眼睛上检索参考数字图像数据，包括在海外眼睛特征上的图像数据。收集实时图像数据，其中包括海角眼部特征上的图像数据。显示数据集的叠加的组合图像，并且基于两个数据集中的海外眼睛特征数据来确定组合图像是否指示它们之间的适当注册。如果注册不充分，则操作其中一个数据集，直到达到足够的注册。系统针对用于定向用于眼科手术的矫正程序的装置和软件。

63. 发明授权

US07789513B2 Adaptive wavefront modulation system and method for refractive laser surgery 有权
$Adaptive wavefront modulation system and method for refractive laser surgery$
标题翻译：屈光激光手术的自适应波前调制系统和方法
公开(公告)号：US07789513B2
公开(公告)日：2010-09-07
申请号：US12106439
申请日：2008-04-21
申请人： George H. Pettit , John A. Campin
发明人： George H. Pettit , John A. Campin
IPC分类号： A61B3/00 , A61B3/10
CPC分类号： A61B3/1015 , A61B3/1035 , A61B3/107 , A61F9/008 , A61F9/00806 , A61F2009/00859 , A61F2009/00872 , A61F2009/0088 , G06F19/00
摘要： A method for improving an accuracy of a prescription for laser-ablation corneal treatment includes the step of receiving a set of raw data comprising Hartmann-Shack image data obtained from a plurality of aberrometer measurements of a patient eye. The Hartmann-Shack data can include, for example, a dot pattern image for each measurement. A set of reconstructed wavefront data calculated from the set of raw data for the plurality of aberrometer measurements is also received. Data on a selected component of the set of raw data and in the set of reconstructed wavefront data are compared. If the selected component data differ more than a predetermined amount between the raw data and the reconstructed wavefront data, the raw data can be further manipulated prior to undertaking laser ablation. In addition, these data are removed from consideration for inclusion in the database of treatment outcomes.
摘要翻译：用于提高激光消融角膜处理的处方精度的方法包括接收包括从患者眼睛的多个像差计测量获得的Hartmann-Shack图像数据的一组原始数据的步骤。 Hartmann-Shack数据可以包括例如每个测量的点图案图像。还接收从多个像差计测量的原始数据集合计算出的一组重建波阵面数据。比较原始数据集合和重建波阵面数据集中的选定分量上的数据。如果所选择的分量数据在原始数据和重建的波前数据之间的预定量不同，则可以在进行激光烧蚀之前进一步操纵原始数据。此外，这些数据从考虑中被删除，以纳入治疗结果数据库。

64. 发明申请

US20070050165A1 System and method for automatic self-alignment of a surgical laser 审中-公开
标题翻译：手术激光自动对准的系统和方法
公开(公告)号：US20070050165A1
公开(公告)日：2007-03-01
申请号：US11510909
申请日：2006-08-28
申请人： Gary Gray , John Bowes , Ricardo Omori
发明人： Gary Gray , John Bowes , Ricardo Omori
IPC分类号： G01M19/00 , G01D3/00 , G06F19/00 , G01P21/00 , G01R35/00 , A61F9/008
CPC分类号： A61B3/00 , A61F9/00804 , A61F2009/00846 , A61F2009/00872 , G16H50/50
摘要： Embodiments of the present invention provide an alignment system operable to align a laser associated with a laser vision correction system. One embodiment of the alignment system comprises a laser source, a beam steering device, a system controller, a partially reflective surface, focusing optics, and an optical detector. The laser source generates a laser beam that the beam steering device receives and redirects along either a surgical pathway or an alignment pathway. The system controller couples to the beam steering device and directs the beam steering device to choose which pathway to be utilized. Additionally, the system controller may control the pulse repetition rate, intensity, beam profile and alignment of the laser beam. The partially reflective surface, within the alignment pathway, partially reflects the laser beam towards alignment coordinates on the surface of the optical detector. Focusing optics, if needed, may further be utilized to focus the partially reflected laser beam on the surface of the optical detector. The optical detector senses the coordinates associated with the illuminated portion of the surface of the optical detector. The system controller compares the coordinates associated with the alignment coordinates and the sensed coordinates and generates a position offset which is used to align the laser beam/steering device.
摘要翻译：本发明的实施例提供了可对准与激光视力校正系统相关联的激光器的对准系统。对准系统的一个实施例包括激光源，光束转向装置，系统控制器，部分反射表面，聚焦光学器件和光学检测器。激光源产生激光束，光束转向装置沿着外科路径或对准路径接收和重定向。系统控制器耦合到光束转向装置并引导光束转向装置选择要使用的通路。此外，系统控制器可以控制激光束的脉冲重复率，强度，光束分布和对准。在对准路径内的部分反射表面部分地将激光束反射到光学检测器表面上的对准坐标。如果需要，可以进一步利用聚焦光学器件将部分反射的激光束聚焦在光学检测器的表面上。光学检测器感测与光学检测器的表面的照射部分相关联的坐标。系统控制器比较与对准坐标和感测坐标相关联的坐标，并产生用于对准激光束/转向装置的位置偏移。

65. 发明授权

US06866661B2 Eye registration and astigmatism alignment control systems and method 有权
标题翻译：眼睛注视和散光对准控制系统及方法
公开(公告)号：US06866661B2
公开(公告)日：2005-03-15
申请号：US10733874
申请日：2003-12-11
申请人： Gary Paul Gray , John Alfred Campin , Qiping Shen
发明人： Gary Paul Gray , John Alfred Campin , Qiping Shen
IPC分类号： A61B3/10 , A61B3/15 , A61F9/007 , A61F9/008 , A61F9/01 , G06T1/00 , G06T7/60 , A61N5/01 , A61N5/067
CPC分类号： A61F9/00804 , A61F2009/00846 , A61F2009/00872 , A61F2009/0088
摘要： An orientation system for corrective eye surgery includes a camera for performing a first image mapping of a patient's eye using a predetermined eye feature and software for processing the first image map to determine an edge location of the feature. A second image mapping of the eye is performed with the patient in a different position. The second image map is processed to locate the predetermined eye feature. Correlation of the mappings is used to calculate an orientational change of the eye between the two positions. The data are used to calculate an adjustment to be applied to a corrective prescription for application by the surgical procedure.
摘要翻译：用于矫正眼科手术的定向系统包括用于使用预定眼睛特征来执行患者眼睛的第一图像映射的相机和用于处理第一图像映射的软件，以确定特征的边缘位置。眼睛的第二次图像映射是在患者处于不同位置的情况下执行的。处理第二图像映射以定位预定的眼睛特征。映射的相关性用于计算两个位置之间眼睛的取向变化。数据用于计算应用于通过外科手术应用的矫正处方的调整。

66. 发明公开

EP2230989A2 VIRTUAL MICROSCOPE SYSTEM FOR MONITORING THE PROGRESS OF CORNEAL ABLATIVE SURGERY AND ASSOCIATED METHODS 审中-公开
标题翻译：虚拟显微镜系统监测进展的一个适当的程序和HORNHAUTABLATIONSVORGANGS作者：
公开(公告)号：EP2230989A2
公开(公告)日：2010-09-29
申请号：EP08868249.7
申请日：2008-12-19
申请人： Alcon RefractiveHorizons, Inc.
发明人： LEBLANC, Richard
IPC分类号： A61B3/13 , G02B21/22 , A61F9/007 , G02B21/06 , G02B21/00 , G02B21/36 , A61F9/01
CPC分类号： G02B21/22 , A61B3/132 , A61F9/00804 , A61F2009/00872 , G02B21/0012
摘要： A system for visualizing an eye of a patient during corneal surgery includes a processor and a first and second camera in signal communication with the processor. The cameras are positionable for focusing on a cornea positioned for surgery. A first and a second display and optics therefor are in signal communication with the processor and are positionable for viewing through a first and a second eyepiece of a stereo microscope, respectively. Software is resident on the processor for receiving a first and second corneal image from the first and second cameras, for processing the received first and second images for display, and for transmitting the processed first and second images to the first and the second displays, respectively, via the display optics. The displays can then be viewed by a surgeon through the microscope at least during the surgery.

67. 发明公开

EP2061412A1 REFLECTOMETRY/INTERFEROMETRY SYSTEM AND METHOD FOR CORNEAL PLANE POSITIONING 有权
标题翻译：反射/干涉和方法用于定位的角膜层间的
公开(公告)号：EP2061412A1
公开(公告)日：2009-05-27
申请号：EP08731386.2
申请日：2008-03-05
申请人： Alcon RefractiveHorizons, Inc.
发明人： HOPLER, Mark A.
IPC分类号： A61F9/008 , A61B3/15
CPC分类号： A61F9/008 , A61B3/1005 , A61B3/102 , A61B3/107 , A61B3/152 , A61F2009/00846
摘要： A system for positioning an eye of a patient, for example, for laser ophthalmic surgery includes a reflectometer adapted to receive as input a reflected beam from an anterior surface of a cornea of an eye of a patient. The interferometer is calibratable to a desired position of the corneal anterior surface. A comparator is in signal communication with the interferometer and is adapted to calculate from the input a difference between an actual position and the desired position of the corneal anterior surface. A device is in signal communication with the comparator for moving the patient a distance in a direction for matching the actual position to the desired position of the corneal anterior surface.

68. 发明授权

EP1800636B1 Image alignment system for use in laser ablation treatment of the cornea and associated methods 有权转让
标题翻译： Ausrichtungssystem zur Verwendung bei Laserablationsbehandlungen der Hornhaut und verwandte Verfahren
公开(公告)号：EP1800636B1
公开(公告)日：2008-09-24
申请号：EP06125850.5
申请日：2006-12-11
申请人： Alcon RefractiveHorizons, Inc.
发明人： LeBlanc, Richard Alan , Eldeeb, Hesham O.
IPC分类号： A61F9/01
CPC分类号： A61F9/008 , A61B3/117 , A61F9/00806 , A61F2009/00872 , A61F2009/0088

69. 发明公开

EP1803426A1 External device for controlling a laser during laser ablation surgery on the cornea ans associated methods 审中-公开
标题翻译：用于Laserablationsoperation到角膜和相关方法期间控制激光的外部设备
公开(公告)号：EP1803426A1
公开(公告)日：2007-07-04
申请号：EP06126145.9
申请日：2006-12-14
申请人： Alcon RefractiveHorizons, Inc.
发明人： Liedel, Kevin , Pettit, George , Luloh, Michael
IPC分类号： A61F9/01 , A61F9/008 , G05G1/14
CPC分类号： G05G1/305 , A61F9/00804 , A61F9/00836 , A61F2009/00872
摘要： A system (10) for controlling a device in ophthalmic refractive surgery includes a processor (17), a controller (19), a treatment laser (11), and a signal receiver (21) is provided. A remote device (22) has a plurality of input elements (23-29). At least one input element when activated is configured to emit a discrete signal that is received by the signal receiver and is mapped to an action to be signaled by the controller. A software package (18) is adapted to translate data from the signal receiver into a signal for directing at least the controller. A method for configuring a system for controlling a device in ophthalmic refractive surgery includes providing a remote device as above. A software package resident on a processor receives and translates signal data from the remote device into control data for a hardware element. The software package is also adapted to output a control signal correlated with the control data to the hardware element. A patient bed (13) may be moved between a first (16) and second (14) laser treatment positions.
摘要翻译：一种用于在眼科屈光手术控制装置系统（10）包括处理器（17），控制器（19），一个治疗激光（11），和一个信号接收机（21）设置。远程设备（22）具有输入元件的多个（23-29）。至少一个输入元件当被激活时被配置为发出没有由信号接收器接收的离散信号和被映射到由控制器发出信号动作。一个软件包（18）是angepasst为至少引导所述控制器从所述信号接收器的数据转换成一个信号。一种用于配置系统，用于控制在眼科屈光手术的装置的方法包括：提供远程装置如上述。处理器上的软件封装常驻接收和反式信号酸酯从远程设备数据转换成控制数据对于硬件元件。软件包是如此angepasst以输出与所述控制数据到硬件元件相关的控制信号。患者床（13）可以在第一（16）和第二（14）激光处理位置之间移动。

70. 发明授权

EP1512379B1 Laser corneal sculpting system 失效
标题翻译：激光角膜雕塑系统
公开(公告)号：EP1512379B1
公开(公告)日：2006-09-06
申请号：EP04078367.2
申请日：1995-04-18
申请人： Alcon RefractiveHorizons, Inc.
发明人： Frey, Rudoph W. , Burkhalter, James H. , Gray, Gary P.
IPC分类号： A61B19/00 , A61F9/00 , A61N5/06
CPC分类号： A61F9/008 , A61F9/00804 , A61F2009/00855 , A61F2009/00872 , A61F2009/00897

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