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    • 56. 发明授权
    • Indoanilines for dyeing keratinous fibers
    • 用于染色角质纤维的印花尼龙
    • US3984402A
    • 1976-10-05
    • US536292
    • 1974-12-24
    • Gregoire KalopissisAndree BugautFrancoise Estradier
    • Gregoire KalopissisAndree BugautFrancoise Estradier
    • A61K8/41A61Q5/10C09B53/02C07C119/14C07D265/36
    • A61Q5/10A61K8/413C09B53/02Y10S424/01Y10S424/02
    • Indoaniline having the formula ##SPC1##Wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 each independently represent a member selected from the group consisting of hydrogen, lower alkyl or halogen with 1 - 2 of these substituents being other than hydrogen; R.sub.5, R.sub.6 and R.sub.7 each independently represent a member selected from the group consisting of hydrogen, lower alkyl and lower alkoxy; R.sub.8 and R.sub.9 each independently represent a member selected from the group consisting of hydrogen, lower alkyl and lower alkyl substituted with a member selected from the group consisting of amino, hydroxy, carbamoyl, piperidinyl and acylamino, R.sub.8 and R.sub.5 or R.sub.9 and R.sub.6 being able to form with the adjacent nitrogen atom a dihydro-oxazine or pyrroline heterocycle; Z represents a member selected from the group consisting of amino, acylamino and hydroxy, and the salts formed by these indoanilines with organic or inorganic acids, in particular, their acetates, oxalates, hydrochlorides, hydrobromides, persulfates, perchlorates and the double zinc salts of these compounds, which can, of course, be in a tautomeric form of that represented by the above formula. These indoanilines are usefully employed for dyeing keratinous fibers, and, in particular, human hair.
    • 具有式WHEREIN R 1,R 2,R 3和R 4的吲哚苯胺各自独立地表示选自氢,低级烷基或卤素的这些取代基中的1-2个不同于氢的成员; R5,R6和R7各自独立地表示选自氢,低级烷基和低级烷氧基的成员; R8和R9各自独立地表示选自氢,低级烷基和被选自氨基,羟基,氨基甲酰基,哌啶基和酰基氨基的基团取代的低级烷基的基团,R 8和R 5或R 9和R 6可以 与相邻的氮原子形成二氢恶嗪或吡咯啉杂环; Z表示选自氨基,酰氨基和羟基的成员,以及由这些吲哚苯胺与有机酸或无机酸形成的盐,特别是其乙酸盐,草酸盐,盐酸盐,氢溴酸盐,过硫酸盐,高氯酸盐和双锌盐 这些化合物当然可以是由上式表示的互变异构体形式。 这些吲哚尼尔可有效地用于染色角质纤维,特别是人的头发。
    • 59. 发明授权
    • Diphenylamines for dyeing keratinous fibers
    • 用于染色角质纤维的二苯胺
    • US3953508A
    • 1976-04-27
    • US432982
    • 1974-01-14
    • Gregoire KalopissisAndree BugautFrancoise Estradier
    • Gregoire KalopissisAndree BugautFrancoise Estradier
    • A61K8/41A61Q5/10C07C103/34
    • A61K8/413A61Q5/10
    • Diphenylamines having the formula ##SPC1##Wherein: Y represents a member selected from the group consisting of a hydroxy and amino, R.sub.1 and R.sub.3, each independently, represent a member selected from the group consisting of hydrogen, halogen, lower alkyl, lower alkoxy, a ureido residue, and -NHCOR wherein R is lower alkyl, R.sub.2 represents a member selected from the group consisting of hydrogen, halogen, lower alkyl, lower alkoxy, a ureido residue, -NHCOR wherein R is lower alkyl, and --NHR.sub.8 wherein R.sub.8 represents a member selected from the group consisting of hydrogen, lower alkyl, lower hydroxyalkyl and carbamyl lower alkyl, with the proviso that when R.sub.2 is --NHR.sub.8, R.sub.3 is not hydrogen R.sub.4, R.sub.5, R.sub.6, and R.sub.7 each independently represent a member selected from the group consisting of hydrogen, halogen, lower alkyl and lower alkoxy, with the proviso that when Y is hydroxy, R.sub.2 is not hydrogen, halogen, lower alkyl or alkoxy and that when Y is amino, at least two of R.sub.1, R.sub.2 and R.sub.3 are other than a hydrogen and R.sub. 2 is not hydrogen when R.sub.4, R.sub.5, R.sub.6 and R.sub.7 are all hydrogen and the acid addition salts of said diphenylamines.
    • 具有式WHEREIN:Y的二苯胺表示选自羟基和氨基的成员,R 1和R 3各自独立地表示选自氢,卤素,低级烷基,低级烷氧基,脲基残基的成员 和-NHCOR,其中R是低级烷基,R 2表示选自氢,卤素,低级烷基,低级烷氧基,脲基残基,-NHCOR,其中R是低级烷基,-NHR 8,其中R8代表成员 选自氢,低级烷基,低级羟烷基和氨甲酰基低级烷基,条件是当R 2为-NHR 8时,R 3不为氢。R4,R5,R6和R7各自独立地表示选自 的氢,卤素,低级烷基和低级烷氧基,条件是当Y是羟基时,R 2不是氢,卤素,低级烷基或烷氧基,当Y是氨基时,R 1,R 2和R 3中的至少两个不同 氢和R 当R4,R5,R6和R7都是氢和所述二苯胺的酸加成盐时,2不是氢。