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51. 发明授权

US5441050A Radiation responsive surgical instrument 失效
标题翻译：辐射反应手术器械
公开(公告)号：US5441050A
公开(公告)日：1995-08-15
申请号：US992622
申请日：1992-12-18
申请人： Marlin O. Thurston , Karl W. Olson
发明人： Marlin O. Thurston , Karl W. Olson
IPC分类号： A61B6/00 , A61B17/00 , A61B19/00 , G01T1/161
CPC分类号： G01T1/161 , A61B17/00 , A61B6/4258 , A61B2017/00079 , A61B2017/00438 , A61B2090/3614
摘要： A crystal containing detector particularly suited for use in immunoguided surgery capable of detecting gamma emissions present at tumor sites. The instrument utilizes a cadmium-zinc-telluride detector crystal which may be retained within a finger mount positioned over the surgeon's finger. Within this mount there also is incorporated a first preamplification stage designed to accumulate charge signals from the detector as well as to drive a relatively short length of cable to a second preamplification stage located, for example, within a housing at the surgeon's upper arm. The small finger mounted probe may be moved between operative orientations at the underside of the tip of the finger to stand-by orientations at the top of the finger adjacent the knuckles. In an additional embodiment, the finger probe incorporates a sodium iodide crystal, the scintillations from which are transmitted via a short length of fiber optic cable to an upper arm mounted housing which contains a photomultiplier tube. Signals from the remote, arm-mounted housing then are transmitted via longer cabling or the like to a control console.
摘要翻译：一种含晶体检测器，特别适用于能够检测肿瘤部位存在的γ发射的免疫手术。仪器使用镉 - 锌 - 碲化物检测器晶体，其可以保留在位于外科医生手指上的手指支架内。在该安装件内还包括第一预放大级，其被设计为累积来自检测器的电荷信号，以及将较短长度的电缆驱动到位于外科医生的上臂处的壳体内的第二预扩增级。小手指安装的探针可以在手指尖端的下侧的操作方向之间移动，以在靠近指关节的手指的顶部处的待机取向。在另外的实施例中，手指探针结合了碘化钠晶体，其中的闪烁通过短长度的光纤电缆传输到包含光电倍增管的上臂安装的外壳。远程手臂式外壳的信号通过较长的布线等传输到控制台。

52. 发明申请

WO0033105A3 MINIMALLY INVASIVE SURGICAL INSTRUMENT FOR TISSUE IDENTIFICATION, DISLODGMENT AND RETRIEVAL AND METHODS OF USE 审中-公开
标题翻译：用于组织识别，分离和检索的最小手术外科手术及使用方法
公开(公告)号：WO0033105A3
公开(公告)日：2000-11-16
申请号：PCT/US9925812
申请日：1999-11-03
申请人： CAREWISE MEDICAL PRODUCTS CORP
发明人： CARROLL ROBERT G , WISE ROBIN A JR
IPC分类号： A61B6/00 , A61B6/03 , A61B10/00 , A61B10/02 , A61B10/04 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/32 , A61B19/00 , G01T1/161
CPC分类号： A61B10/0266 , A61B6/032 , A61B6/4057 , A61B6/425 , A61B6/4258 , A61B6/4423 , A61B6/506 , A61B10/02 , A61B10/04 , A61B10/06 , A61B17/22031 , A61B17/32056 , A61B2010/0225 , A61B2017/00079 , A61B2017/320044 , A61B2017/320048 , A61B2090/3908 , A61B2090/392 , G01T1/161
摘要： A probe or sheath for use on a probe for detecting and removing radioactively tagged tissue, e.g., a sentinel lymph node, within the body of a living being. The people or sheath and probe is arranged to be inserted through a small percutaneous portal into the patient's body and is movable to various positions adjacent the tagged tissue to detect the presence of radiation therefrom so that it can be positioned immediately adjacent that tissue (12) to ensnare or trap that tissue. The probe or sheath and probe can then be removed from the being's body, carrying the tagged tissue with it. The probe may be constructed to make use of a scintillation crystal, a collimator, adjustable or fixed, and a backshielding lightpipe. A blunt dissecting device (206) is provided as part of the sheath or as part of the probe itself to aid in separating the tagged tissue from adjacent tissue without injury to the adjacent tissue. The probe may be a fully integrated, self-powered unit.
摘要翻译：用于探针的探针或鞘，用于检测和去除活体内体内的放射性标记的组织，例如前哨淋巴结。人或鞘和探针被布置成通过小的经皮入口插入患者体内并且可移动到与标记的组织相邻的各个位置以检测其中的辐射的存在，使得其可以紧邻该组织（12）定位，以捕获或捕获该组织。然后可以将探针或鞘和探针从身体移除，携带标记的组织。探针可以被构造成利用闪烁晶体，准直器，可调节或固定的以及背光灯管。提供钝器解剖装置（206）作为护套的一部分或作为探针本身的一部分，以帮助将标记的组织与相邻组织分离而不损伤相邻组织。探头可以是完全集成的自供电单元。

53. 发明申请

WO00033105A2 MINIMALLY INVASIVE SURGICAL INSTRUMENT FOR TISSUE IDENTIFICATION, DISLODGMENT AND RETRIEVAL AND METHODS OF USE 审中-公开
标题翻译：用于组织识别，解毒和检索的最小手术外科手术及使用方法
公开(公告)号：WO00033105A2
公开(公告)日：2000-06-08
申请号：PCT/US1999/025812
申请日：1999-11-03
IPC分类号： A61B6/00 , A61B6/03 , A61B10/00 , A61B10/02 , A61B10/04 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/32 , A61B19/00 , G01T1/161
CPC分类号： A61B10/0266 , A61B6/032 , A61B6/4057 , A61B6/425 , A61B6/4258 , A61B6/4423 , A61B6/506 , A61B10/02 , A61B10/04 , A61B10/06 , A61B17/22031 , A61B17/32056 , A61B2010/0225 , A61B2017/00079 , A61B2017/320044 , A61B2017/320048 , A61B2090/3908 , A61B2090/392 , G01T1/161
摘要： A probe or sheath for use on a probe for detecting and removing radioactively tagged tissue, e.g., a sentinel lymph node, within the body of a living being. The probe or sheath and probe is arranged to be inserted through a small percutaneous portal into the patient's body and is movable to various positions adjacent the tagged tissue to detect the presence of radiation therefrom so that it can be positioned immediately adjacent that tissue to ensnare or trap that tissue. The probe or sheath and probe can then be removed from the being's body, carrying the tagged tissue with it. The probe may be constructed to make use of a scintillation crystal, a collimator, adjustable or fixed, and a backshielding lightpipe. A blunt dissecting device is provided as part of the sheath or as part of the probe itself to aid in separating the tagged tissue from adjacent tissue without injury to the adjacent tissue. The probe may be a fully integrated, self-powered unit.
摘要翻译：用于探针的探针或鞘，用于检测和去除生物体内的放射性标记的组织，例如前哨淋巴结。探针或鞘和探针被布置成通过小的经皮入口插入到患者的身体中并且可移动到与标记的组织相邻的各个位置以检测其中的辐射的存在，使得其可以被定位成紧邻该组织以被捕获或陷阱那个组织。然后可以将探针或鞘和探针从身体移除，携带标记的组织。探针可以被构造成利用闪烁晶体，准直器，可调节或固定的以及背光灯管。提供钝器解剖装置作为护套的一部分或作为探针本身的一部分，以有助于将标记的组织与相邻组织分离而不损伤相邻组织。探头可以是完全集成的自供电单元。

54. 发明申请

WO99025248A1 MINIMALLY INVASIVE SURGICAL PROBE FOR TISSUE IDENTIFICATION AND RETRIEVAL AND METHOD OF USE 审中-公开
标题翻译：用于组织识别和检索的最小入侵外科手术和使用方法
公开(公告)号：WO99025248A1
公开(公告)日：1999-05-27
申请号：PCT/US1998/024033
申请日：1998-11-12
IPC分类号： A61B6/00 , A61B6/03 , A61B10/00 , A61B10/02 , A61B10/04 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/32 , A61B19/00 , G01T1/161
CPC分类号： A61B10/02 , A61B6/032 , A61B6/4057 , A61B6/425 , A61B6/4258 , A61B6/4423 , A61B10/0266 , A61B10/04 , A61B10/06 , A61B17/22031 , A61B17/32056 , A61B2010/0225 , A61B2017/00079 , A61B2017/320044 , A61B2017/320048 , A61B2090/3908 , A61B2090/392 , G01T1/161
摘要： The present invention is a probe (20) for detecting, and removing radioactively tagged tissue (12), e.g., a sentinel lymph node, within the body of a living being. The probe is arranged to be inserted through a small percutaneous portal into the patient's body, and is movable to various positions adjacent the tagged tissue (12) to detect the presence of radiation therefrom so that the probe can be positioned immediately adjacent that tissue to ensnare or trap it. The probe can then be removed from the patient's body, carrying the tagged tissue with it. The probe may be constructed to make use of a scintillation crystal (52), a collimator, adjustable or fixed, and a back shielding light pipe (64).
摘要翻译：本发明是用于检测和去除活体内体内的放射性标记的组织（例如前哨淋巴结）的探针（20）。探针被布置成通过小的经皮入口插入到患者的身体中，并且可移动到与标记的组织（12）相邻的各个位置以检测其中的辐射的存在，使得探针可以紧邻该组织定位或陷阱。然后可以从患者身体移除探针，携带标记的组织。探针可以构造成利用闪烁晶体（52），可调节或固定的准直器和后屏蔽光管（64）。

55. 发明授权

KR100181304B1 방사선 응답반응성 외과용 기구 失效
标题翻译：辐射反应反应性手术器械
公开(公告)号：KR100181304B1
公开(公告)日：1999-04-01
申请号：KR1019930028465
申请日：1993-12-18
申请人： 나비디아 바이오파마슈티컬즈, 인크.
发明人： 마린오,터스톤 , 칼더블유.올슨
IPC分类号： A61B17/00
CPC分类号： G01T1/161 , A61B6/4258 , A61B17/00 , A61B2017/00079 , A61B2017/00438 , A61B2090/3614
摘要： 본 발명은 종양 부위에 존재하는 감마 방사선을 검출할 수 있는 면역안내 수술에 사용하기 특히 적합한 결정체 포함 검출기에 관한 것이다. 이 기구는 외과의사의 손가락위에 배치된 손가락 장착물내에 유지될 수 있는 카드뮴-아연-텔루라이드 검출기 결정체를 이용한다. 이 장착물내에는 또한 외과의사의 상박의 하우징내에 위치한 제2 예비증폭단으로 비교적 짧은 길이의 케이블을 인출하기 위한 것 뿐 아니라 검출기로부터 전하 시그날을 축전하도록 고안된 제1 예비증폭단이 설치되어 있다. 손가락에 장착된 소형 프로브는 손가락 팁의 하단면의 작동 위치와 관절에 인접한 손가락 상부의 대기 위치 사이로 이동할 수 있다. 추가의 구체예에서, 손가락 프로브는 요오드화 나트륨 결정체를 포함하며, 이로부터의 섬광은 짧은 길이의 광 섬유 케이블을 통해 광증배관을 포함하는 팔 상단에 장착된 하우징으로 전송된다. 그후, 원거리의, 팔에 장착된 하우징으로부터의 시그날은 긴 케이블등을 통해 제어 콘솔로 전송된다.

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