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51. 发明申请

US20050166983A1 Flush mounted waste disposal service panel assembly 审中-公开
标题翻译：嵌入式废物处理服务面板组件
公开(公告)号：US20050166983A1
公开(公告)日：2005-08-04
申请号：US10772043
申请日：2004-02-03
申请人： James Shaw , Philip Jones
发明人： James Shaw , Philip Jones
IPC分类号： B64D37/00 , G05D7/00
CPC分类号： B64C1/1453 , B64D11/02 , Y02T50/46 , Y10T137/6906
摘要： The waste disposal service panel assembly includes a housing, waste drain valve, rinse/fill valve, handle assembly and service panel door. The housing has a tubular side wall and a base near one end of the side wall. The waste drain valve is at least partially mounted within the housing through the base. The waste drain valve includes an outlet positioned within the housing and an inlet configured to couple to a waste collection tank within a aircraft. The service panel door is pivotally coupled to the housing near an end of the side wall remote from the base. The service panel door has an outer surface configured to substantially match an outer contour of the aircraft's skin, and an outer cap coupled to an inner surface of the service panel door. The outer cap is configured and dimensioned to mate with the outlet to seal the outlet when the service panel door is closed.
摘要翻译：废物处理维修面板组件包括壳体，排泄阀，冲洗/填充阀，手柄组件和维修面板门。壳体具有管状侧壁和靠近侧壁一端的底座。废物排放阀至少部分地通过底座安装在壳体内。废物排放阀包括位于壳体内的出口和配置成耦合到飞行器内的废物收集箱的入口。维修面板门可靠近靠近底座的侧壁的端部连接到壳体。维修面板门具有被配置为基本上匹配飞行器的皮肤的外轮廓的外表面和联接到维修面板门的内表面的外盖。外盖的构造和尺寸设计为与出口配合，以在维修面板门关闭时密封出口。

52. 发明授权

US6141546A Mobile telephone systems 失效
标题翻译：移动电话系统
公开(公告)号：US6141546A
公开(公告)日：2000-10-31
申请号：US953126
申请日：1997-10-17
申请人： Howard John Thomas , Rupinder Singh Oberoi , Christopher Parker , Philip Jones
发明人： Howard John Thomas , Rupinder Singh Oberoi , Christopher Parker , Philip Jones
IPC分类号： H04B17/00 , H04W24/00 , H04W24/08 , H04B1/00
CPC分类号： H04W24/08 , H04B17/391 , H04W24/00 , H04W24/06 , H04W24/10 , H04W28/16 , H04W72/02 , H04W88/08
摘要： In a mobile cellular communication system, adjacent basestations BS1-BS4 are assigned different selections of different frequency channels to communicate with mobiles in their cells (10, etc.). To improve system quality and capacity, a basestation selects a frequency channel which is not assigned to it or any neighbour station, and makes test communications on that frequency channel with mobiles (e.g. MS1) in its cell. The basestation assesses the potential performance of that frequency channel, and neighbour basestations can monitor for potential interference on that frequency channel. The information so gathered can be analysed by an operations maintenance station OMC.
摘要翻译：在移动蜂窝通信系统中，相邻基站BS1-BS4被分配不同频率信道的不同选择，以与其小区（10等）中的移动台通信。为了提高系统质量和容量，基站选择一个没有分配给它或任何相邻站的频道，并在其小区中用移动台（例如MS1）在该频道上进行测试通信。基站评估该频道的潜在性能，邻居基站可以监视该频道上的潜在干扰。所收集的信息可以由操作维护站OMC进行分析。

53. 发明申请

US20130158003A1 HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF 有权
公开(公告)号：US20130158003A1
公开(公告)日：2013-06-20
申请号：US13700051
申请日：2011-05-26
申请人： John Emmerson Campbell , Michael Charles Hewitt , Philip Jones , Linghong Xie
发明人： John Emmerson Campbell , Michael Charles Hewitt , Philip Jones , Linghong Xie
IPC分类号： C07D403/06 , C07D409/06 , C07D405/14 , C07D409/14 , C07D498/04 , C07D417/06 , C07D413/06 , C07D487/04 , C07D471/14 , C07D471/04 , C07D401/14
CPC分类号： C07D498/06 , A61K31/4164 , A61K31/4178 , A61K31/4709 , A61K31/498 , A61K31/4985 , A61K31/506 , A61K31/517 , A61K31/5383 , C07D233/58 , C07D401/06 , C07D401/14 , C07D403/06 , C07D405/14 , C07D409/06 , C07D409/14 , C07D413/06 , C07D417/06 , C07D471/04 , C07D471/06 , C07D471/14 , C07D487/04 , C07D491/056 , C07D498/04 , C07D498/14 , C07D519/00
摘要： Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one embodiment, the compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as CNS disorders and metabolic disorders, including, but not limited to, e.g., neurological disorders, psychosis, schizophrenia, obesity, and diabetes.

54. 发明申请

US20130048783A1 LANDING GEAR ATTACHMENT 有权
标题翻译：接地齿轮附件
公开(公告)号：US20130048783A1
公开(公告)日：2013-02-28
申请号：US13569528
申请日：2012-08-08
申请人： Andrija Ekmedzic , Mario Straccia , Philip Jones
发明人： Andrija Ekmedzic , Mario Straccia , Philip Jones
IPC分类号： B64C25/10
CPC分类号： B64C25/04
摘要： A landing gear attachment apparatus (100) hasa landing gear side bearing retention arrangement (104) connected to an aircraft side attachment apparatus (102), held together by a series of fuse pins. The interaction between a fuse pin carrier and a trunnion block varies the amount of load required to separate the landing gear from the fuselage depending on the direction of the load.
摘要翻译：起落架附接装置（100）具有连接到飞行器侧连接装置（102）的起落架侧轴承保持装置（104），其通过一系列熔丝销保持在一起。保险丝销托架和耳轴座之间的相互作用根据负载方向改变将起落架与机身分离所需的负载量。

55. 发明授权

US08188084B2 Pyridinone and pyridazinone derivatives as inhibitors of poly (ADP-ribose) polymerase (PARP) 有权
标题翻译：作为聚（ADP-核糖）聚合酶（PARP）抑制剂的吡啶酮和哒嗪酮衍生物
公开(公告)号：US08188084B2
公开(公告)日：2012-05-29
申请号：US12227513
申请日：2007-05-25
申请人： Philip Jones , Olaf Kinzel , Giovanna Pescatore , Laura Llauger Bufi , Carsten Schultz-Fademrecht , Federica Ferrigno
发明人： Philip Jones , Olaf Kinzel , Giovanna Pescatore , Laura Llauger Bufi , Carsten Schultz-Fademrecht , Federica Ferrigno
IPC分类号： C07D401/12 , A61P35/00 , A61P9/10 , A61P29/00
CPC分类号： C07D471/04 , A61K31/435 , A61K31/495 , C07D237/14 , C07D401/10 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D403/14 , C07D405/10 , C07D471/10 , C07D487/04 , C07D491/10
摘要： The present invention relates to compounds of formula I: and pharmaceutically acceptable salts or tautomers thereof which are inhibitors of poly(ADP-ribose)polymerase (PARP) and thus useful for the treatment of cancer, inflammatory diseases, reperfusion injuries, ischaemic conditions, stroke, renal failure, cardiovascular diseases, vascular diseases other than cardiovascular diseases, diabetes mellitus, neurodegenerative diseases, retroviral infections, retinal damage, skin senescence and UV-induced skin damage, and as chemo- or radiosensitizers for cancer treatment.
摘要翻译：本发明涉及式I化合物及其药学上可接受的盐或互变异构体，其是聚（ADP-核糖）聚合酶（PARP）的抑制剂，因此可用于治疗癌症，炎性疾病，再灌注损伤，缺血性病症，中风，肾衰竭，心血管疾病，心血管疾病以外的血管疾病，糖尿病，神经变性疾病，逆转录病毒感染，视网膜损伤，皮肤衰老和紫外线诱发的皮肤损伤，以及用于癌症治疗的化学或放射增敏剂。

56. 发明授权

US08126451B2 Synchronous CDMA communication system 有权
标题翻译：同步CDMA通信系统
公开(公告)号：US08126451B2
公开(公告)日：2012-02-28
申请号：US12016663
申请日：2008-01-18
申请人： Carlo Luschi , Steve Allpress , Philip Jones
发明人： Carlo Luschi , Steve Allpress , Philip Jones
IPC分类号： H04W4/00
CPC分类号： H04B17/345 , H04B1/7115 , H04B17/27 , H04B17/318 , H04B17/336 , H04L25/0212 , H04L25/0224 , H04L25/03019
摘要： Methods are described of processing signals received over a wireless communication channel by a receiver in a wireless cellular network. A method includes receiving a sequence of signal samples. The received sequence of samples can be used to estimate at least one channel coefficient for at least one transmission path. An estimate of an orthogonality factor can be generated based on said at least one channel coefficient. An estimate of the disturbance can be generated based on said at least one estimated channel coefficient. An estimate of input signal power can be generated using the received sequence. An estimate of cell geometry can be generated using the estimated orthogonality factor, estimated disturbance, and estimated input signal power. The estimate of cell geometry can be used in processing received data samples. Related methods of processing digital samples are described. Related receivers are also described.
摘要翻译：描述了处理由无线蜂窝网络中的接收机在无线通信信道上接收的信号的方法。一种方法包括接收信号样本序列。所接收的样本序列可以用于估计至少一个传输路径的至少一个信道系数。可以基于所述至少一个信道系数来生成正交因子的估计。可以基于所述至少一个估计的信道系数来产生扰动的估计。可以使用接收到的序列来生成输入信号功率的估计。可以使用估计的正交因子，估计的干扰和估计的输入信号功率来生成小区几何的估计。单元几何的估计可用于处理接收的数据样本。描述处理数字样本的相关方法。还描述了相关接收机。

57. 发明授权

US08080573B2 Heterocycle substituted amide and sulfur amide derivatives as histone deacetylase (hdac) inhibitors 有权
标题翻译：杂环取代的酰胺和硫酰胺衍生物作为组蛋白脱乙酰酶（hdac）抑制剂
公开(公告)号：US08080573B2
公开(公告)日：2011-12-20
申请号：US12084269
申请日：2006-10-26
申请人： Philip Jones , Jesus Maria Ontoria Ontoria
发明人： Philip Jones , Jesus Maria Ontoria Ontoria
IPC分类号： A61K31/4164 , C07D233/54
CPC分类号： C07D403/12 , C07D233/64 , C07D409/14
摘要： The present invention related to compounds of formula (I): or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof. Compounds of the present invention are inhibitors of histone deacetylase (HDAC) and are useful for treating cellular proliferative diseases, including cancer. Compounds of the present invention are useful for treating or preventing neurodegenerative diseases, schizophrenia and stroke among other diseases.
摘要翻译：本发明涉及式（I）化合物：或其药学上可接受的盐，立体异构体或互变异构体。本发明化合物是组蛋白脱乙酰酶（HDAC）的抑制剂，可用于治疗包括癌症在内的细胞增殖性疾病。本发明的化合物可用于治疗或预防神经变性疾病，精神分裂症和中风等疾病。

58. 发明授权

US08071623B2 Amide substituted indazoles as poly(ADP-ribose)polymerase(PARP) inhibitors 有权
标题翻译：酰胺取代的吲唑作为聚（ADP-核糖）聚合酶（PARP）抑制剂
公开(公告)号：US08071623B2
公开(公告)日：2011-12-06
申请号：US12006993
申请日：2008-01-08
申请人： Philip Jones , Jesus Maria Ontoria Ontoria , Rita Scarpelli , Carsten Schultz-Fademrecht
发明人： Philip Jones , Jesus Maria Ontoria Ontoria , Rita Scarpelli , Carsten Schultz-Fademrecht
IPC分类号： A61K31/445 , C07D231/56
CPC分类号： C07D401/10 , A61K31/4439
摘要： The present invention relates to compounds of formula I: and pharmaceutically acceptable salts, stereoisomers or tautomers thereof which are inhibitors of poly (ADP-ribose) polymerase (PARP) and thus useful for the treatment of cancer, inflammatory diseases, reperfusion injuries, ischemic conditions, stroke, renal failure, cardiovascular diseases, vascular diseases other than cardiovascular diseases, diabetes, neurodegenerative diseases, retroviral infection, retinal damage or skin senescence and UV-induced skin damage, and as chemo- and/or radiosensitizers for cancer treatment.
摘要翻译：本发明涉及式I化合物及其药学上可接受的盐，立体异构体或互变异构体，其是聚（ADP-核糖）聚合酶（PARP）的抑制剂，因此可用于治疗癌症，炎性疾病，再灌注损伤，缺血性疾病，中风，肾衰竭，心血管疾病，心血管疾病以外的血管疾病，糖尿病，神经变性疾病，逆转录病毒感染，视网膜损伤或皮肤衰老以及UV诱导的皮肤损伤，以及用作癌症治疗的化学和/或放射增敏剂。

59. 发明申请

US20110183989A1 SATURATED BICYCLIC HETEROCYCLIC DERIVATIVES AS SMO ANTAGONISTS 有权
标题翻译：饱和双环杂环衍生物作为SMO拮抗剂
公开(公告)号：US20110183989A1
公开(公告)日：2011-07-28
申请号：US13060718
申请日：2009-08-28
申请人： Danila Branca , Federica Ferrigno , Jose Ignacio Martin Hernando , Philip Jones , Olaf Kinzel , Savina Malancona , Ester Muraglia , Maria Cecilia Palumbi , Giovanna Pescatore , Rita Scarpelli
发明人： Danila Branca , Federica Ferrigno , Jose Ignacio Martin Hernando , Philip Jones , Olaf Kinzel , Savina Malancona , Ester Muraglia , Maria Cecilia Palumbi , Giovanna Pescatore , Rita Scarpelli
IPC分类号： A61K31/4985 , C07D487/04 , A61P35/00
CPC分类号： C07D487/04
摘要： The present invention relates to compounds of formula I: and pharmaceutically acceptable salts or tautomers thereof which are inhibitors of the Sonic Hedgehog pathway, in particular Smoantagonists. Thus the compounds of this invention are useful for the treatment of diseases associated with abnormal hedgehog pathway activation, including cancer, for example basal cell carcinoma, medulloblastoma, prostate, pancreatic, breast, colon, bone and small cell lung cancers, and cancers of the upper GI tract.
摘要翻译：本发明涉及式I化合物及其药学上可接受的盐或互变异构体，其是Sonic Hedgehog途径的抑制剂，特别是Smoantagonists。因此，本发明的化合物可用于治疗与异常hedgehog途径活化相关的疾病，包括癌症，例如基底细胞癌，成神经管细胞瘤，前列腺，胰腺癌，乳腺癌，结肠癌，骨细胞和小细胞肺癌，以及癌症上胃肠道

60. 发明申请

US20110053911A1 TRICYCLIC DERIVATIVES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) 失效
标题翻译：作为聚（ADP-RIBOSE）聚合酶（PARP）的抑制剂的三聚衍生物
公开(公告)号：US20110053911A1
公开(公告)日：2011-03-03
申请号：US12922270
申请日：2009-03-13
申请人： Raffaele Ingenito , Philip Jones , Laura Llauger Bufi , Jesus Maria Ontoria Ontoria , Rita Scarpelli
发明人： Raffaele Ingenito , Philip Jones , Laura Llauger Bufi , Jesus Maria Ontoria Ontoria , Rita Scarpelli
IPC分类号： A61K31/55 , C07D471/16 , C07D487/06 , A61K31/4375 , A61K31/551 , A61K31/438 , A61P35/00 , A61P9/10 , A61P29/00 , A61P3/10 , A61P9/00 , A61P27/02 , A61P17/00
CPC分类号： C07D471/06 , C07D471/16
摘要： The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts or tautomers thereof which are inhibitors of poly(ADP-ribose)polymerase (PARP) and thus useful for the treatment of cancer, inflammatory diseases, reperfusion injuries, ischaemic conditions, stroke, renal failure, cardiovascular diseases, vascular diseases other than cardiovascular diseases, diabetes mellitus, neurodegenerative diseases, retroviral infections, retinal damage, skin senescence and UV-induced skin damage, and as chemo- or radiosensitizers for cancer treatment.
摘要翻译：本发明涉及作为聚（ADP-核糖）聚合酶（PARP）的抑制剂的式（I）化合物及其药学上可接受的盐或互变异构体，因此可用于治疗癌症，炎性疾病，再灌注损伤，缺血状况，中风，肾衰竭，心血管疾病，心血管疾病以外的血管疾病，糖尿病，神经变性疾病，逆转录病毒感染，视网膜损伤，皮肤衰老和紫外线诱发的皮肤损伤，以及用于癌症治疗的化学或放射增敏剂。

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