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51. 发明专利

CA3048821A1 COMPOSITIONS, METHODS, AND MEDICAL COMPOSITIONS FOR TREATMENT OF AND MAINTAINING THE HEALTH OF THE LIVER 未知
公开(公告)号：CA3048821A1
公开(公告)日：2017-01-19
申请号：CA3048821
申请日：2016-07-13
申请人： UNIGEN INC
发明人： JIA QI , YIMAN MESFIN , JIAO PING , HONG MEI FENG , MOORE BREANNA
IPC分类号： A61K36/481 , A61K36/185 , A61P1/16
摘要： Compositions and methods for treatment of and maintaining the health of the liver are disclosed that include a mixture of plant extracts, wherein the plant extracts comprise at least one Myristica extract, at least one Astragalus extract, and at least one Schizandra extract. Compositions and methods for treatment of and maintaining the health of the liver are disclosed that include a mixture of plant extracts, wherein the plant extracts comprise at least one Myristica extract enriched for one or more lignans, including phenylpropanoids, dimers and polymers, at least one Astragalus extract enriched for one or more polysaccharides and triterpenoids, and at least one Schizandra extract enriched for one or more lignans and organic acids. Compositions and methods for treatment of and maintaining the health of the liver are disclosed that include a mixture of plant extracts, wherein the plant extracts comprise at least one Myristica extract, at least one Astragalus extract, and at least one Poria extract.

52. 发明专利

MX2013008890A COMPOSICIONES DE BAKUCHIOL PARA EL TRATAMIENTO DE HIPERPIGMENTACION POST-INFLAMATORIA. 未知
公开(公告)号：MX2013008890A
公开(公告)日：2013-10-17
申请号：MX2013008890
申请日：2012-02-02
申请人： UNIGEN INC
发明人： JIA QI , HONG MEI FENG , BROWNELL LIDIA ALFARO
IPC分类号： A61K31/05 , A61K31/60 , A61P17/00 , A61P29/00
摘要： Se describen métodos para tratar pigmentación en exceso, incluyendo el tratamiento de hiperpigmentación post-inflamatoria (PIH). El método descrito comprende la administración de una composición que comprende bakuchiol sustancialmente libre de furanocoumarinas a un mamífero. También se describen composiciones que comprenden bakuchiol y métodos para su preparación.

53. 发明专利

AU2012212153A1 Bakuchiol compositions for treatment of post inflammatory hyperpigmentation 未知
公开(公告)号：AU2012212153A1
公开(公告)日：2013-08-29
申请号：AU2012212153
申请日：2012-02-02
申请人： UNIGEN INC
发明人： HONG MEI FENG , JIA QI , BROWNELL LIDIA ALFARO
IPC分类号： A61K31/05 , A61K31/60 , A61P17/00 , A61P29/00
摘要： Methods for treating excess pigmentation, including treatment of post inflammatory hyperpigmentation (PIH), are disclosed. The disclosed methods comprise administration of a composition comprising bakuchiol substantially free of furanocoumarins to a mammal. Compositions comprising bakuchiol and methods for their preparation are also disclosed.

54. 发明专利

ES2384506T3 1-(3-Metil-2,4-dimetoxifenil)-3-(2',4'-dihidroxifenil)-propano como un potente inhibidor de tirosinasa 未知
公开(公告)号：ES2384506T3
公开(公告)日：2012-07-06
申请号：ES05762186
申请日：2005-05-27
申请人： UNIGEN PHARMACEUTICALS INC , JIA QI , ZHAO JI FU , UNIGEN INC , JIA QI , ZHAO JI FU
发明人： JIA QI , ZHAO JI-FU
IPC分类号： A61K31/015 , A61K31/05 , A61K31/085 , A61K31/09 , A61K31/357 , A61K31/40 , A61K31/704 , A61P17/00 , A61P35/00 , C07C39/15 , C07C39/367 , C07C43/23 , C07C45/67 , C07C49/835 , C07C215/74 , C07D233/02 , C07D321/12 , C07D323/00
摘要： El compuesto 1-(3-metil-2,4-dimetoxifenil)-3-(2',4'-dihidroxifenil)-propano.

55. 发明专利

AT538778T 未知
公开(公告)号：AT538778T
公开(公告)日：2012-01-15
申请号：AT05762186
申请日：2005-05-27
申请人： UNIGEN INC , JIA QI , ZHAO JI-FU
发明人： JIA QI , ZHAO JI-FU
IPC分类号： A61K31/015 , A61K31/05 , A61K31/085 , A61K31/09 , A61K31/357 , A61K31/40 , A61K31/704 , A61P17/00 , A61P35/00 , C07C39/15 , C07C39/367 , C07C43/23 , C07C45/67 , C07C49/835 , C07C215/74 , C07D321/12
摘要： The present invention implements a strategy that combines an enzyme inhibition assay with a chemical dereplication process to identify active plant extracts and the particular compounds—diarylalkanes and/or diarylalkanols within those extracts that specifically inhibit binuclear enzyme function. Included in the present invention are compositions of matter comprised of one or more of diarylalkanes and/or diarylalkanols, which inhibit the activity of binuclear enzymes, particularly tyrosinase and which prevent melanin overproduction. The present invention also provides a method for inhibiting the activity of a binuclear enzyme, particularly tyrosinase and a method for preventing and treating diseases and conditions related to binuclear enzyme function. The present invention further includes a method for preventing and treating melanin overproduction and diseases and conditions of the skin related thereto. The method for preventing and treating diseases and conditions related to binuclear enzyme function and melanin overproduction is comprised of administering to a host in need thereof an effective amount of a composition comprising one or more diarylalkanes and/or diarylalkanols synthesized and/or isolated from one or more plants together with a pharmaceutically acceptable carrier.

56. 发明专利

AU2021216474A1 Compositions comprising extracts of Aplinia and other plants for improving joint health and treating arthritis 未知
公开(公告)号：AU2021216474A1
公开(公告)日：2022-08-25
申请号：AU2021216474
申请日：2021-02-07
申请人： UNIGEN INC
发明人： YIMAM MESFIN , JIAO PING , HORM TERESA , HONG MEI , O'NEAL ALEXANDRIA , JIA QI
IPC分类号： A61K36/21 , A61K31/00 , A61K36/575 , A61K36/67 , A61K36/9062 , A61P19/02
摘要： Medicinal plant extracts and their bioactives from Alpinia, Magnolia, Kochia and Piper/Pepper are disclosed herein in combination or alone in regulating homeostasis of chondrocytes, extracellular matrix, articular cartilage, and phenotype of arthritis that lead to enhanced anabolic functions of chondrocytes, increased renewal/rebuilding/regeneration of extracellular matrix and articular cartilage, and improved phenotype of osteoarthritis and rheumatoid arthritis.

57. 发明专利

AU2012212153B9 Bakuchiol compositions for treatment of post inflammatory hyperpigmentation 未知
公开(公告)号：AU2012212153B9
公开(公告)日：2017-05-11
申请号：AU2012212153
申请日：2012-02-02
申请人： UNIGEN INC
发明人： HONG MEI FENG , JIA QI , BROWNELL LIDIA ALFARO
IPC分类号： A61K31/05 , A61K31/60 , A61P17/00 , A61P29/00
摘要： Methods for treating excess pigmentation, including treatment of post inflammatory hyperpigmentation (PIH), are disclosed. The disclosed methods comprise administration of a composition comprising bakuchiol substantially free of furanocoumarins to a mammal. Compositions comprising bakuchiol and methods for their preparation are also disclosed.

58. 发明专利

AU2012212153B2 Bakuchiol compositions for treatment of post inflammatory hyperpigmentation 未知
公开(公告)号：AU2012212153B2
公开(公告)日：2017-04-06
申请号：AU2012212153
申请日：2012-02-02
申请人： UNIGEN INC
发明人： HONG MEI FENG , JIA QI , BROWNELL LIDIA ALFARO
IPC分类号： A61K31/05 , A61K31/60 , A61P17/00 , A61P29/00
摘要： Methods for treating excess pigmentation, including treatment of post inflammatory hyperpigmentation (PIH), are disclosed. The disclosed methods comprise administration of a composition comprising bakuchiol substantially free of furanocoumarins to a mammal. Compositions comprising bakuchiol and methods for their preparation are also disclosed.

59. 发明专利

CA2991773A1 COMPOSITIONS, METHODS, AND MEDICAL COMPOSITIONS FOR TREATMENT OF AND MAINTAINING THE HEALTH OF THE LIVER 未知
公开(公告)号：CA2991773A1
公开(公告)日：2017-01-19
申请号：CA2991773
申请日：2016-07-13
申请人： UNIGEN INC
发明人： JIA QI , YIMAM MESFIN , JIAO PING , HONG MEI FENG , MOORE BREANNA
IPC分类号： A61K36/79 , A61K36/076 , A61K36/185 , A61K36/481 , A61P1/16
摘要： Compositions and methods for treatment of and maintaining the health of the liver are disclosed that include a mixture of plant extracts, wherein the plant extracts comprise at least one Myristica extract, at least one Astragalus extract, and at least one Schizandra extract. Compositions and methods for treatment of and maintaining the health of the liver are disclosed that include a mixture of plant extracts, wherein the plant extracts comprise at least one Myristica extract enriched for one or more lignans, including phenylpropanoids, dimers and polymers, at least one Astragalus extract enriched for one or more polysaccharides and triterpenoids, and at least one Schizandra extract enriched for one or more lignans and organic acids. Compositions and methods for treatment of and maintaining the health of the liver are disclosed that include a mixture of plant extracts, wherein the plant extracts comprise at least one Myristica extract, at least one Astragalus extract, and at least one Poria extract.

60. 发明专利

CA2991768A1 COMPOSITIONS, METHODS, AND MEDICAL COMPOSITIONS FOR TREATMENT OF AND MAINTAINING THE HEALTH OF THE LIVER 未知
公开(公告)号：CA2991768A1
公开(公告)日：2017-01-19
申请号：CA2991768
申请日：2016-07-12
申请人： UNIGEN INC
发明人： JIA QI , YIMAM MESFIN , JIAO PING , HONG MEI FENG , MOORE BREANNA
IPC分类号： A61K36/79 , A61K36/282 , A61K36/886 , A61K45/00
摘要： Compositions and methods for treatment of and maintaining the health of the liver are disclosed that include a mixture of plant extracts, wherein the plant extracts comprise at least one Artemisia extract, at least one Aloe gel powder, and at least one Schizandra extract. Compositions and methods for treatment of and maintaining the health of the liver are disclosed that include a mixture of plant extracts, wherein the plant extracts comprise at least one Artemisia extract enriched for at least one polymer or biopolymer, at least one Aloe gel powder enriched for at least one chromone, and at least one Schizandra extract enriched for at least one lignan and organic acid.

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