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51. 发明授权

US5364883A Isocarbocyclins for the treatment of liver and kidney diseases 失效
标题翻译： Isocarbocyclins用于治疗肝肾疾病
公开(公告)号：US5364883A
公开(公告)日：1994-11-15
申请号：US55787
申请日：1993-05-03
申请人： Kiyoshi Bannai , Toshio Tanaka , Yoshinori Kato , Tamotsu Koyama , Satoshi Asano , Akira Ohtsu , Seizi Kurozumi , Makoto Ogawa , Yoshio Mori
发明人： Kiyoshi Bannai , Toshio Tanaka , Yoshinori Kato , Tamotsu Koyama , Satoshi Asano , Akira Ohtsu , Seizi Kurozumi , Makoto Ogawa , Yoshio Mori
IPC分类号： A61K31/557
CPC分类号： A61K31/557
摘要： 16(S)-Isocarbacyclins have been found to the useful in the treatment of liver and kidney diseases.
摘要翻译：已发现16（S） - 碳青霉烯可用于治疗肝肾疾病。

52. 发明授权

US5290812A Phenoxyalkylcarboxylic acid derivatives and process of preparing the same 失效
标题翻译：苯氧基烷基羧酸衍生物及其制备方法
公开(公告)号：US5290812A
公开(公告)日：1994-03-01
申请号：US814477
申请日：1991-12-30
申请人： Mitsuo Ohashi , Toshio Tanaka , Norihisa Ishikawa , Tetsuya Kishi
发明人： Mitsuo Ohashi , Toshio Tanaka , Norihisa Ishikawa , Tetsuya Kishi
IPC分类号： C07C323/22 , A61K31/19 , A61K31/235 , C07C69/612
CPC分类号： C07C323/22
摘要： Phenoxyalkylcarboxylic acid derivatives represented by the following formula (I) ##STR1## having a strong and selective leukotriene antagonistic action and useful for prophylaxis and therapy of allergic diseases as asthma and processes of preparing the same.
摘要翻译：由下式（I）表示的苯氧基烷基羧酸衍生物（*化学结构*）（1）具有强烈和选择性的白三烯拮抗作用并且可用于预防和治疗作为哮喘的过敏性疾病及其制备方法。

53. 发明授权

US5054391A Thermal stencil sheet assembly with stencil sheet temporarily detachable from frame 失效
标题翻译：具有可从框架中拆卸的薄壁板的热断裂片组件
公开(公告)号：US5054391A
公开(公告)日：1991-10-08
申请号：US518406
申请日：1990-05-03
申请人： Toshio Tanaka , Noboru Hayama , Satoru Komata , Kazuo Sakamoto
发明人： Toshio Tanaka , Noboru Hayama , Satoru Komata , Kazuo Sakamoto
IPC分类号： B41N1/24
CPC分类号： B41N1/248
摘要： A thermal stencil sheet assembly of the type having an annular frame made of a cardboard and a thermal stencil sheet attached to one face of the frame as fixed thereto along an entire peripheral portion thereof with or without an ink pressing sheet made of an ink impermeable sheet attached to another face of the frame, wherein the frame is assembled of a first frame element made of a relatively thin sheet material and a second frame element made of a cardboard, the two frame elements being detachably and reattachably bound together by a slippery surface provided on the first frame element being attached to a layer of a sticky binding material provided on the second frame element.

54. 发明授权

US4979923A Stuffed toy with heater and phase changing heat storage 失效
标题翻译：充气玩具加热器和相变储热
公开(公告)号：US4979923A
公开(公告)日：1990-12-25
申请号：US453778
申请日：1989-12-20
申请人： Toshio Tanaka
发明人： Toshio Tanaka
IPC分类号： A61F7/00 , A61F7/02 , A63H3/00 , A63H3/36 , H05B3/00
CPC分类号： A61F7/007 , A63H3/003 , H05B3/00 , A61F2007/0201 , A61F2007/0292 , F28D20/02
摘要： A stuffed toy with a heater is disclosed, which comprises a cover configured to resemble a predetermined object and a latent heat storage material disposed in the stuffing in the cover. When the latent heat storage material is heated it undergoes a transition from the solid phase to the liquid phase and stores a heat of dissolution. When it undergoes transition from the liquid phase to the solid phase, it gives off heat so as to maintain the temperature of the toy relatively constant for long periods of time.
摘要翻译：公开了一种具有加热器的填充玩具，其包括构造成类似于预定物体的盖和设置在盖中的填充物中的潜热蓄热材料。当潜热蓄热材料被加热时，其经历从固相转移到液相并储存溶解热。当它经历从液相到固相的转变时，它发出热量，以便长时间保持玩具的温度相对恒定。

55. 发明授权

US4921995A Process for producing 16-substituted prostaglandines 失效
标题翻译：生产16-取代的前列腺素的方法
公开(公告)号：US4921995A
公开(公告)日：1990-05-01
申请号：US153881
申请日：1988-02-09
申请人： Toshio Tanaka , Atsuo Hazato , Seizi Kurozumi , Masahiro Koga
发明人： Toshio Tanaka , Atsuo Hazato , Seizi Kurozumi , Masahiro Koga
IPC分类号： C07C405/00
CPC分类号： C07C405/0033 , C07C405/00
摘要： A novel process for manufacturing 16-substituted .DELTA..sup.7 -prostaglandin Es, which include compounds expressed by the following formula (I), their enanantiomers, or their mixtures of arbitrary mixing ratio, ##STR1## wherein R.sup.1 indicates COOR.sup.2, CH.sub.2 OR.sup.3, or COCH.sub.2 OR.sup.3, in which R.sup.2 indicates a hydrogen atom, a substituted or unsubstituted C.sub.1 -C.sub.10 alkyl group, a substituted or unsubstituted C.sub.3 -C.sub.10 cycloalkyl group, or a substituted or unsubstituted phenyl group, and R.sup.3 indicates a hydrogen atom, a tri(C.sub.1 -C.sub.7) hydrocarbon silyl group, a group which forms an acetal bond together with the oxygen atom of a hydroxyl group, or a C.sub.2 -C.sub.7 acyl group; R.sup.4 and R.sup.5 are identical or different, each representing a hydrogen atom, a tri(C.sub.1 -C.sub.7) hydrocarbon silyl group, or a group which forms an acetal bond together with the oxygen atom of a hydroxyl group; R.sup.6 indicates a hydrogen atom, a C.sub.1 -C.sub.4 alkyl group, or a vinyl group; R.sup.7 indicates a linear or branched C.sub.3 -C.sub.8 alkyl group, an alkyenyl group, or an alkynyl group, which may contain an oxygen atom; a phenyl group, a phenoxy group, or a C.sub.3 - C.sub.10 cycloalkyl group, which may be substituted; or a linear or branched C.sub.1 -C.sub.5 alkyl group which is substituted by a C.sub.1 -C.sub.6 alkoxy group, a phenyl group, a phenoxy group, or a C.sub.3 -C.sub.10 cycloalkyl group, which may be substituted; and Y indicates CH.sub.2 X or XCH.sub.2, in which X represents an ethylene group, a cis -or trans-vinylene group, or an ethynylene group.

56. 发明授权

US4888422A Process for producing dimethylaminomethyl copper phthalocyanine and/or its derivatives 失效
标题翻译：制备二甲基氨基甲基铜酞菁和/或其衍生物的方法
公开(公告)号：US4888422A
公开(公告)日：1989-12-19
申请号：US279796
申请日：1988-12-05
申请人： Toshio Takei , Toshio Tanaka
发明人： Toshio Takei , Toshio Tanaka
IPC分类号： C09B67/50 , C09B47/12 , C09B47/16 , C09B67/22
CPC分类号： C09B47/16 , C09B67/0035
摘要： Dimethylaminomethyl copper phthalocyanine and/or its derivative represented by the general formula, ##STR1## wherein CuPc represents a copper phthalocyanine residue, X represents a hydrogen atom, a halogen atom, the group --SO.sub.3 H or the group --CH.sub.2 OH, and m and n independently represent an integer of 1 to 4,and containing only small amounts of by-products is produced by a process comprising reacting aminomethyl copper phthalocyanine and/or its derivatives represented by the general formula ##STR2## wherein CuPc, X, m and n are as defined above, with formic acid and a formaldehyde-generating substance at a temperature of 130.degree. to 150.degree. C. under a pressure of 3 to 10 kg/cm.sup.2 (gauge).
摘要翻译：二甲基氨基甲基铜酞菁和/或其衍生物由下式表示，其中CuPc表示铜酞菁残基，X表示氢原子，卤素原子，-SO 3 H基或-CH 2 OH基，m 并且n独立地表示1〜4的整数，仅含有少量副产物的方法包括使氨基甲基铜酞菁和/或其通式（II）表示的衍生物反应，其中CuPc，X ，m和n如上所定义，在130〜150℃的温度下，在3〜10kg / cm 2（表压）的压力下与甲酸和产生甲醛的物质接触。

57. 发明授权

US4689426A 5-alkylidene-2-halo-4-substituted-2-cyclopentenone and process for production thereof 失效
标题翻译： 5-亚烷基-2-卤代-4-取代-2-环戊烯酮及其制备方法
公开(公告)号：US4689426A
公开(公告)日：1987-08-25
申请号：US628107
申请日：1984-07-05
申请人： Satoshi Sugiura , Toshio Tanaka , Seizi Kurozumi
发明人： Satoshi Sugiura , Toshio Tanaka , Seizi Kurozumi
IPC分类号： C07C405/00 , C07C177/00
CPC分类号： C07C405/00
摘要： Novel 5-alkylidene-2-halo-4-substituted-2-cyclopentenone and process for production thereof. The novel 5-alkylidene-2-halo-4-substituted-2-cyclopentenones are represented by the following formula (I): ##STR1## wherein R.sub.a represents a substituted or unsubstituted aliphatic hydrocarbon group having 1 to 12 carbon atoms or a substituted or unsubstituted phenyl group, R.sub.b represents a substituted or unsubstituted aliphatic hydrocarbon group having 1 to 12 carbon atoms, and X represents a halogen atom. The novel cyclopentenones possess excellent pharmaceutical activities including anti-tumor activity, antiviral activity and antimicrobial activity.
摘要翻译：新型5-亚烷基-2-卤代-4-取代-2-环戊烯酮及其制备方法。新型5-亚烷基-2-卤代-4-取代-2-环戊烯酮由下式（I）表示：其中R a表示取代或未取代的碳原子数为1至12的脂族烃基或取代或未取代的苯基，Rb表示取代或未取代的碳原子数1〜12的脂肪族烃基，X表示卤素原子。新型环戊烯酮具有优异的药物活性，包括抗肿瘤活性，抗病毒活性和抗菌活性。

58. 发明授权

US4239478A Check circuit for combustion process control timer 失效
标题翻译：燃烧过程控制定时器检查电路
公开(公告)号：US4239478A
公开(公告)日：1980-12-16
申请号：US940369
申请日：1978-09-07
申请人： Toshio Tanaka , Sumio Nakagawa
发明人： Toshio Tanaka , Sumio Nakagawa
IPC分类号： F23N5/20 , F23N5/24 , H03K17/28 , F23N5/00 , F23Q9/08 , F23Q23/00
CPC分类号： F23N5/203 , F23N2027/12
摘要： A check circuit for checking operation of timers of a digital type combustion process control apparatus comprises flip-flops each having a preset terminal. The preset state of the flip-flops is inverted by an operation starting signal. The inversion is detected by a detector circuit the output signal of which is utilized for driving the control circuits for a combustion apparatus. The detector circuit is composed of a flip-flop circuit having input terminals applied with the operation initiating signal and the inverted output signal from the timer circuit.
摘要翻译：用于检查数字式燃烧过程控制装置的定时器的操作的检查电路包括各自具有预设端子的触发器。触发器的预置状态由操作开始信号反相。反相由其输出信号用于驱动燃烧装置的控制电路的检测器电路检测。检测器电路由具有施加操作启动信号的输入端和来自定时器电路的反相输出信号的触发电路组成。

59. 发明授权

US4233309A Novel 1-substituted-3-acylpyrrole derivatives, platelet aggregation inhibitors containing them, as active ingredients, and processes for production of said derivatives 失效
标题翻译：新颖的1-取代-3-酰基吡咯衍生物，含有它们的血小板聚集抑制剂作为活性成分，以及所述衍生物的制备方法
公开(公告)号：US4233309A
公开(公告)日：1980-11-11
申请号：US966050
申请日：1978-12-04
申请人： Toshio Tanaka , Akira Otsu , Seizi Kurozumi , Toshio Wakabayashi
发明人： Toshio Tanaka , Akira Otsu , Seizi Kurozumi , Toshio Wakabayashi
IPC分类号： C07D207/32 , C07D207/325 , C07D207/333 , C07D207/00 , A61K31/40
CPC分类号： C07D207/325 , C07D207/333
摘要： Novel 1-substituted-3-acylpyrrole derivatives of the formula ##STR1## wherein all symbols are as defined in the specification; and platelet aggregation inhibiting agents comprising them as active ingredients. These novel 1-substituted-3-acylpyrrole derivatives are prepared by condensing the corresponding 1-substituted pyrrole derivatives with the corresponding acylating agents in the presence of acid catalysts, and if desired, subjecting the products to oxidation, hydrolysis, amidation or acetal-forming reaction. These 1-substituted-3-acylpyrrole derivatives exhibit unique properties in that they have superior platelet aggregation inhibiting actions with low antiinflammatory activity.
摘要翻译：新颖的式（I）的1-取代-3-酰基吡咯衍生物，其中所有符号如说明书中所定义; 和包含它们作为活性成分的血小板聚集抑制剂。这些新的1-取代-3-酰基吡咯衍生物通过在酸催化剂存在下将相应的1-取代吡咯衍生物与相应的酰化剂缩合，并且如果需要，使产物经历氧化，水解，酰胺化或缩醛形成反应。这些1-取代-3-酰基吡咯衍生物具有独特的性质，因为它们具有优异的血小板聚集抑制作用，具有低的抗炎活性。

60. 发明授权

US4127887A Safety test circuit for combustion control apparatus 失效
标题翻译：燃烧控制装置的安全测试电路
公开(公告)号：US4127887A
公开(公告)日：1978-11-28
申请号：US825725
申请日：1977-08-18
申请人： Toshio Tanaka , Juichi Honda , Sadao Mimori , Kazutoshi Ikegami
发明人： Toshio Tanaka , Juichi Honda , Sadao Mimori , Kazutoshi Ikegami
IPC分类号： F23N5/20 , F23N5/24 , G01R31/00 , H02H3/26
CPC分类号： G01R31/006 , F23N5/242 , F23N2027/12 , F23N2027/16 , F23N2027/18 , F23N5/20
摘要： A safety test circuit for a combustion control apparatus. This safety test circuit is used to check the off-failure of a safety transistor actuating a safety relay which acts to stop the operation of controlled units in the event of mal-combustion or the like, and also to check the on-failure of a control transistor actuating a control relay which controls the controlled units. An operation instruction signal and the collector potential of the safety transistor are applied to a logic circuit including a flip-flop and logic gates so that the off-failure of the safety transistor can be driven to check, utilizing the electrical signal propagation delay time of the elements constituting the logic circuit, before the propagation delay time has elapsed. The logic circuit is also used for similarly checking the on-failure of the control transistor. A check signal may be additionally applied to the logic circuit so that these transistors can be tested during the continuous operation of the combustion control apparatus.
摘要翻译：一种用于燃烧控制装置的安全测试电路。该安全测试电路用于检查致动安全继电器的安全晶体管的失效，该安全继电器用于在发生不良燃烧等情况下停止受控单元的操作，并且还检查一个控制晶体管驱动控制受控单元的控制继电器。将操作指令信号和安全晶体管的集电极电位施加到包括触发器和逻辑门的逻辑电路，使得可以驱动安全晶体管的断开故障来检查，利用电信号传播延迟时间在传播延迟时间过去之前构成逻辑电路的元件。逻辑电路也用于类似地检查控制晶体管的导通故障。可以将校验信号额外地施加到逻辑电路，使得可以在燃烧控制装置的连续操作期间对这些晶体管进行测试。

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