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51. 发明授权

US5549855A Optical element molding method 失效
标题翻译：光学元件成型法
公开(公告)号：US5549855A
公开(公告)日：1996-08-27
申请号：US260969
申请日：1994-06-15
申请人： Hiroshi Nakanishi , Norihisa Saito , Toshinori Ando , Hisakazu Morinaga
发明人： Hiroshi Nakanishi , Norihisa Saito , Toshinori Ando , Hisakazu Morinaga
IPC分类号： B29C33/38 , B29C45/37 , B29C45/76 , B29D11/00 , B29L11/00 , G02B3/00 , G02B26/10 , G02B26/12
CPC分类号： B29C33/3835 , B29C45/766 , B29D11/00009 , G02B26/124 , B29L2011/00 , Y10S425/808
摘要： It is an object of this invention to provide an optical element molding method capable of correcting local processing errors in an optical element without increasing the size of an apparatus or raising the manufacturing cost. To achieve this object, an optical element molding method includes the first step of setting molding conditions before molding of said optical element, such that a constant shape error is stably formed on an optical function surface of the optical element, the second step of dividing the optical function surface of the optical element to be molded under the molding conditions into a plurality of regions, and approximating the shape error by using a function so that the divided regions are continuous in the boundaries between the regions, the third step of processing the shape of the cavity surface of the optical-insert member into a shape by which the constant shape error is canceled, on the basis of the function obtained in the second step, and the fourth step of molding the optical element by using the optical insert member processed in the third step.
摘要翻译：本发明的目的是提供一种能够在不增加设备尺寸或提高制造成本的情况下校正光学元件中的局部加工误差的光学元件模制方法。为了实现该目的，光学元件成型方法包括：在成型前设定成形条件的第一步骤，使得在光学元件的光学功能表面上稳定地形成恒定的形状误差;第二步骤，在模塑条件下将要模制的光学元件的光学功能表面形成多个区域，并且通过使用功能来近似形状误差，使得分割区域在区域之间的边界中是连续的，处理形状的第三步骤基于第二步骤中获得的功能，将光学插入构件的空腔表面形成为消除恒定形状误差的形状;以及第四步骤，通过使用加工的光学插入构件来模制光学元件在第三步。

52. 发明授权

US5075051A Molding process and apparatus for transferring plural molds to plural stations 失效
标题翻译：用于将多个模具转移到多个站的成型工艺和设备
公开(公告)号：US5075051A
公开(公告)日：1991-12-24
申请号：US385364
申请日：1989-07-27
申请人： Kazuhiko Ito , Eiichi Yamazaki , Kunio Ohtaki , Fumio Korayashi , Yoshihisa Masuda , Hiroshi Nakanishi , Kiyozo Suzuki , Yuichi Miyoshi
发明人： Kazuhiko Ito , Eiichi Yamazaki , Kunio Ohtaki , Fumio Korayashi , Yoshihisa Masuda , Hiroshi Nakanishi , Kiyozo Suzuki , Yuichi Miyoshi
IPC分类号： B29C45/04 , B29C45/76 , B29D11/00
CPC分类号： B29D11/00432 , B29C45/0433 , B29C45/76
摘要： A molding apparatus transfers plural molds in succession through a temperature elevating step, an injection molding step, pressurized cooling step and a molded article removing step. The apparatus is provided with plural cooling presses for the pressurized cooling step and so constructed as to prevent the stagnation in the transfer of the molds according to the molding conditions and the number of molds.
摘要翻译：成型设备通过升温步骤，注射成型步骤，加压冷却步骤和模制品去除步骤连续地传送多个模具。该设备设置有用于加压冷却步骤的多个冷却压机，并且被构造成防止根据成型条件和模具数量的模具的传送停滞。

53. 发明授权

US4553138A Fire alarm system 失效
标题翻译：火警系统
公开(公告)号：US4553138A
公开(公告)日：1985-11-12
申请号：US360907
申请日：1982-03-23
申请人： Yoshitaka Nakanishi , Hiroshi Nakanishi , Takashi Nakanishi
发明人： Yoshitaka Nakanishi , Hiroshi Nakanishi , Takashi Nakanishi
IPC分类号： G08B13/00 , G08B17/00 , G08B19/00 , G08B21/04 , G08B25/01 , G08B25/00
CPC分类号： G08B25/016 , G08B17/00 , G08B21/043 , G08B21/0446 , G08B21/0461
摘要： A system for detecting an outbreak of fire, for giving an audible alarm therefore as well as provided with a tactile alarm for disabled persons. This system comprises a main body to be attached to the ceiling, the wall and other structures, and a switch box to be provided at a position apart from the main body. The main body includes a fire sensing element for sensing an outbreak of fire, and an alarm to make an alarm sound based on a detection signal of the fire sensing element. The switch box includes a control switch capable of directly actuating the alarm. The switch box is further provided with a vibrating-type buzzer for vibrating the switch box so that a deaf or disabled person will be able to confirm the actuation of the alarm when it is actuated.
摘要翻译：一种用于检测火灾爆发的系统，因此发出声音报警，并为残疾人提供触觉报警。该系统包括要附接到天花板的主体，壁和其他结构，以及设置在离开主体的位置处的开关盒。主体包括用于感测火灾爆发的火灾感测元件，以及基于火灾感测元件的检测信号发出报警声的警报。开关盒包括一个能够直接启动报警器的控制开关。开关盒还设置有用于振动开关盒的振动式蜂鸣器，使得聋人或残疾人能够在启动时确认警报器的致动。

54. 发明授权

US07919617B2 Cytokine inhibitors 有权
标题翻译：细胞因子抑制剂
公开(公告)号：US07919617B2
公开(公告)日：2011-04-05
申请号：US12637712
申请日：2009-12-14
申请人： Erik Boman , Susana Conde Ceide , Russell Dahl , Nancy G. J. Delaet , Justin Ernst , Antonio Garrido Montalban , Jeffrey Kahl , Christopher Larson , Stephen Miller , Hiroshi Nakanishi , Edward Roberts , Eddine Saiah , Robert Sullivan , Zhinjun Wang
发明人： Erik Boman , Susana Conde Ceide , Russell Dahl , Nancy G. J. Delaet , Justin Ernst , Antonio Garrido Montalban , Jeffrey Kahl , Christopher Larson , Stephen Miller , Hiroshi Nakanishi , Edward Roberts , Eddine Saiah , Robert Sullivan , Zhinjun Wang
IPC分类号： C07D265/30 , A61K31/5377
CPC分类号： A61K31/416 , C07D207/40 , C07D231/12 , C07D231/40 , C07D239/47 , C07D249/12 , C07D253/075 , C07D295/088 , C07D403/12 , C07D471/04 , C07D487/04 , Y02A50/401 , Y02A50/409 , Y02A50/411
摘要： The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are useful as anti-inflammatory agents. There are further provided methods for the preparation of such agents and their use in preventing or treating conditions mediated by cytokines such as arthritis.
摘要翻译：本发明提供可用作细胞因子抑制剂的低分子量化合物及其组合物。特别地，本发明的化合物可用作抗炎剂。还提供了制备这些试剂的方法及其在预防或治疗由细胞因子如关节炎介导的病症中的用途。

55. 发明授权

US07897599B2 Cytokine inhibitors 有权
公开(公告)号：US07897599B2
公开(公告)日：2011-03-01
申请号：US12637714
申请日：2009-12-14
申请人： Erik Boman , Susana Conde Ceide , Russell Dahl , Nancy G. J. Delaet , Justin Ernst , Antonio Garrido Montalban , Jeffrey Kahl , Christopher Larson , Stephen Miller , Hiroshi Nakanishi , Edward Roberts , Eddine Saiah , Robert Sullivan , Zhinjun Wang
发明人： Erik Boman , Susana Conde Ceide , Russell Dahl , Nancy G. J. Delaet , Justin Ernst , Antonio Garrido Montalban , Jeffrey Kahl , Christopher Larson , Stephen Miller , Hiroshi Nakanishi , Edward Roberts , Eddine Saiah , Robert Sullivan , Zhinjun Wang
IPC分类号： A61K31/535 , C07D265/30
CPC分类号： A61K31/416 , C07D207/40 , C07D231/12 , C07D231/40 , C07D239/47 , C07D249/12 , C07D253/075 , C07D295/088 , C07D403/12 , C07D471/04 , C07D487/04 , Y02A50/401 , Y02A50/409 , Y02A50/411
摘要： The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are useful as anti-inflammatory agents. There are further provided methods for the preparation of such agents and their use in preventing or treating conditions mediated by cytokines such as arthritis.

56. 发明授权

US07749999B2 Alpha-ketoamides and derivatives thereof 失效
标题翻译： α-酮酰胺及其衍生物
公开(公告)号：US07749999B2
公开(公告)日：2010-07-06
申请号：US10939324
申请日：2004-09-10
申请人： Erik Boman , Susana Conde Ceide , Russell Dahl , Nancy G. J. Delaet , Justin Ernst , Antonio Garrido Montalban , Hiroshi Nakanishi , Edward Roberts , Eddine Saiah , Robert Sullivan , Zhinjun Wang , Jeffrey Kahl , Christopher Larson
发明人： Erik Boman , Susana Conde Ceide , Russell Dahl , Nancy G. J. Delaet , Justin Ernst , Antonio Garrido Montalban , Hiroshi Nakanishi , Edward Roberts , Eddine Saiah , Robert Sullivan , Zhinjun Wang , Jeffrey Kahl , Christopher Larson
IPC分类号： A61K31/535 , C07D265/30
CPC分类号： A61K31/416 , C07D207/40 , C07D231/12 , C07D231/40 , C07D239/47 , C07D249/12 , C07D253/075 , C07D295/088 , C07D403/12 , C07D471/04 , C07D487/04 , Y02A50/401 , Y02A50/409 , Y02A50/411
摘要： The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are useful as anti-inflammatory agents. There are further provided methods for the preparation of such agents and their use in preventing or treating conditions mediated by cytokines such as arthritis.
摘要翻译：本发明提供可用作细胞因子抑制剂的低分子量化合物及其组合物。特别地，本发明的化合物可用作抗炎剂。还提供了制备这些试剂的方法及其在预防或治疗由细胞因子如关节炎介导的病症中的用途。

57. 发明申请

US20100093735A1 CYTOKINE INHIBITORS 有权
公开(公告)号：US20100093735A1
公开(公告)日：2010-04-15
申请号：US12637714
申请日：2009-12-14
申请人： Erik Boman , Susana Conde Ceide , Russell Dahl , Nancy G.J. Delaet , Justin Ernst , Antonio Garrido Montalban , Jeffrey Kahl , Christopher Larson , Stephen Miller , Hiroshi Nakanishi , Edward Roberts , Eddine Saiah , Robert Sullivan , Zhinjun Wang
发明人： Erik Boman , Susana Conde Ceide , Russell Dahl , Nancy G.J. Delaet , Justin Ernst , Antonio Garrido Montalban , Jeffrey Kahl , Christopher Larson , Stephen Miller , Hiroshi Nakanishi , Edward Roberts , Eddine Saiah , Robert Sullivan , Zhinjun Wang
IPC分类号： A61K31/535 , C07D295/155
CPC分类号： A61K31/416 , C07D207/40 , C07D231/12 , C07D231/40 , C07D239/47 , C07D249/12 , C07D253/075 , C07D295/088 , C07D403/12 , C07D471/04 , C07D487/04 , Y02A50/401 , Y02A50/409 , Y02A50/411
摘要： The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are useful as anti-inflammatory agents. There are further provided methods for the preparation of such agents and their use in preventing or treating conditions mediated by cytokines such as arthritis.

58. 发明授权

US07432573B2 Surface-spintronics device 有权
标题翻译：表面自旋电子器件
公开(公告)号：US07432573B2
公开(公告)日：2008-10-07
申请号：US10561616
申请日：2004-06-23
申请人： Hideaki Kasai , Hiroshi Nakanishi , Tomoya Kishi
发明人： Hideaki Kasai , Hiroshi Nakanishi , Tomoya Kishi
IPC分类号： H01L29/82
CPC分类号： H01L43/08 , B82Y25/00 , G11C11/16 , H01F10/007
摘要： A surface-spintronic device operating on a novel principles of operations may be implemented as a spin conducting, a spin switching or a spin memory device. It includes a magnetic atom thin film (13) layered on a surface of a solid crystal (12) and a drain and a source electrodes (14)and (15) disposed at two locations on the magnetic atom thin film, respectively, whereby a spin splitting surface electronic state band formed in a system comprising said solid crystal(12) surface and said magnetic atom thin film (13) is utilized to obtain a spin polarized current flow. With electrons spin-polarized in a particular direction injected from the source electrode (15), controlling the direction of magnetization of the magnetic atom thin film (13) allows switching on and off the conduction of such injected electrons therethrough. Also, with the use of the magnetization holding function of the magnetic atom thin film (13), it is possible to realize a spin memory device that can operate to write information on controlling the direction of magnetization of the magnetic atom thin film (13) and that can operate to read information on detecting the electrodes (15, 14).
摘要翻译：以新颖的操作原理操作的表面自旋电子器件可以被实现为自旋导通，自旋切换或自旋存储器件。它包括分别在固体晶体（12）的表面上分层的磁性原子薄膜（13）和设置在磁性原子薄膜上的两个位置处的漏极和源极（14）和（15），由此利用在包括所述固体晶体（12）表面和所述磁性原子薄膜（13）的系统中形成的旋转分裂表面电子状态带来获得自旋极化电流。利用从源电极（15）注入的特定方向自旋极化的电子，控制磁性原子薄膜（13）的磁化方向允许这种注入的电子的导通和导通。此外，通过使用磁性原子薄膜（13）的磁化保持功能，可以实现能够操作以写入关于控制磁性原子薄膜（13）的磁化方向的信息的自旋存储装置，并且可以操作以读取关于检测电极（15,14）的信息。

59. 发明授权

US06972809B2 Path shifting optical device having polarization correcting section and optical display system including same 失效
标题翻译：具有偏振校正部的路径移动光学器件和包括其的光学显示系统
公开(公告)号：US06972809B2
公开(公告)日：2005-12-06
申请号：US10321350
申请日：2002-12-18
申请人： Hiroshi Nakanishi
发明人： Hiroshi Nakanishi
IPC分类号： G02F1/01 , H04N9/31 , G02F1/1335 , G02B5/30 , G02F1/13 , G09G3/20
CPC分类号： H04N9/3105 , G02F1/0136 , H04N9/3114
摘要： An optical device includes an optical path shifter that has at least one optical path shifting section. The optical path shifting section includes: a polarization modulator for changing the polarization state of an incoming light ray; and a birefringent element for shifting the optical path of an outgoing light ray of the polarization modulator based on the polarization state of the outgoing light ray. The optical device further includes a polarization corrector, which selectively changes the polarization state of an outgoing light ray of the optical path shifter, thereby keeping the polarization state of an outgoing light ray of the polarization corrector substantially unchanged no matter where the optical path has been shifted.
摘要翻译：光学装置包括具有至少一个光路移动部分的光路移动器。光路移动部分包括：用于改变入射光线的偏振状态的偏振调制器; 以及用于基于出射光线的偏振状态移动偏振调制器的出射光线的光路的双折射元件。光学装置还包括偏振校正器，其选择性地改变光路移动器的出射光线的偏振状态，从而保持偏振校正器的出射光线的偏振状态基本上不变，无论光路已经在何处转移

60. 发明申请

US20050245528A1 Reverse-turn mimetics and compositions and methods related thereto 有权
标题翻译：反转模拟物及其组合物和方法
公开(公告)号：US20050245528A1
公开(公告)日：2005-11-03
申请号：US11175920
申请日：2005-07-06
申请人： Gangadhar Nagula , Jan Urban , Hwa-Ok Kim , Christopher Lum , Hiroshi Nakanishi
发明人： Gangadhar Nagula , Jan Urban , Hwa-Ok Kim , Christopher Lum , Hiroshi Nakanishi
IPC分类号： C07D487/04 , A61K31/498
CPC分类号： C07D487/04
摘要： Conformationally constrained compounds that mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins having the following structure are disclosed: wherein A, R1, R2, R2a and R3 are as defined herein. Such compounds have utility over a wide range of fields, including use as diagnostic and therapeutic agents. In particular, compounds of this invention are useful in pharmaceutical compositions as anti-inflammatory agents as well as inhibitors of central nervous disorders. Libraries containing the compounds of this invention are also disclosed, as well as methods for screening the same to identify biologically active members.
摘要翻译：公开了具有以下结构的模拟具有生物活性肽和蛋白质的反转转区的二级结构的构象约束的化合物：其中A，R 1，R 2，R 2a和R 3'如本文所定义。这些化合物可用于广泛的领域，包括用作诊断和治疗剂。特别地，本发明的化合物可用作作为抗炎剂的药物组合物以及中枢神经障碍的抑制剂。还公开了含有本发明化合物的文库，以及筛选该文库以鉴定生物活性成员的方法。

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