专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

51. 发明授权

US5955428A DNA encoding human metallothionein 失效
标题翻译：编码人金属硫蛋白的DNA
公开(公告)号：US5955428A
公开(公告)日：1999-09-21
申请号：US123850
申请日：1997-07-28
申请人： Jennifer L. Hillman , Surya K. Goli
发明人： Jennifer L. Hillman , Surya K. Goli
IPC分类号： C12N15/09 , A61K38/00 , A61P35/00 , A61P37/00 , A61P39/02 , C07K14/825 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/12 , C12Q1/68
CPC分类号： C07K14/825 , A61K38/00
摘要： The present invention provides a human metallothionein (HMBP-I) and polynucleotides which identify and encode HMBP-I. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HMBP-I and a method for producing HMBP-I. The invention also provides for agonists, antibodies, or antagonists specifically binding HMBP-I, and their use, in the prevention and treatment of diseases associated with expression of HMBP-I. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HMBP-I for the treatment of diseases associated with the expression of HMBP-I. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HMBP-I.
摘要翻译：本发明提供人金属硫蛋白（HMBP-1）和识别和编码HMBP-1的多核苷酸。本发明还提供了包含编码HMBP-1的核酸序列和生产HMBP-1的方法的遗传工程表达载体和宿主细胞。本发明还提供了特异性结合HMBP-1的激动剂，抗体或拮抗剂及其用于预防和治疗与HMBP-1表达有关的疾病的用途。此外，本发明提供了反义分子用于编码HMBP-1的多核苷酸用于治疗与HMBP-1表达相关的疾病的用途。本发明还提供利用多核苷酸或其片段或其补体以及特异性结合HMBP-1的抗体的诊断测定法。

52. 发明授权

US5948625A Method of screening for ATP synthase Fo subunit 失效
标题翻译：筛选ATP合酶Fo亚基的方法
公开(公告)号：US5948625A
公开(公告)日：1999-09-07
申请号：US94080
申请日：1998-06-09
申请人： Jennifer L. Hillman , Surya K. Goli
发明人： Jennifer L. Hillman , Surya K. Goli
IPC分类号： A61K38/00 , C12N9/14 , C07H21/04 , C12Q1/68
CPC分类号： C12N9/14 , A61K38/00
摘要： The present invention provides a human ATP synthase d subunit (ASYSD) and polynucleotides which encode ASYSD. The invention also provides expression vectors, host cells, agonists, antisense molecules, antibodies, or antagonists. The invention also provides methods for producing ASYSD and for treating disorders associated with expression of ASYSD.
摘要翻译：本发明提供了人ATP合成酶d亚基（ASYSD）和编码ASYSD的多核苷酸。本发明还提供表达载体，宿主细胞，激动剂，反义分子，抗体或拮抗剂。本发明还提供了用于产生ASYSD和用于治疗与ASYSD表达相关的疾病的方法。

53. 发明授权

US5935931A Human apoptosis-related calcium-binding protein 失效
公开(公告)号：US5935931A
公开(公告)日：1999-08-10
申请号：US094212
申请日：1998-06-09
申请人： Jennifer L. Hillman , Surya K. Goli
发明人： Jennifer L. Hillman , Surya K. Goli
IPC分类号： G01N33/53 , A61K38/00 , A61K45/00 , A61P1/00 , A61P1/16 , A61P9/10 , A61P13/12 , A61P17/06 , A61P19/02 , A61P25/00 , A61P25/16 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/14 , A61P31/20 , A61P31/22 , A61P35/00 , A61P37/04 , A61P37/06 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12Q1/68 , A61K38/04 , A61K38/17 , C07K7/00
CPC分类号： C07K14/4747 , C07K14/4702 , A61K38/00
摘要： The present invention provides a human apoptosis-related calcium-binding protein (HARC) and polynucleotides which identify and encode HARC. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HARC and a method for producing HARC. The invention also provides for agonists, antibodies, or antagonists specifically binding HARC, and their use, in the prevention and treatment of diseases associated with expression of HARC. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HARC for the treatment of diseases associated with the expression of HARC. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HARC.

54. 发明授权

US5858712A CDNA encoding a LEA-motif developmental protein homologous to avian px19 失效
标题翻译： CDNA编码与禽类px19同源的LEA基序发育蛋白
公开(公告)号：US5858712A
公开(公告)日：1999-01-12
申请号：US796676
申请日：1997-02-06
申请人： Jennifer L. Hillman , Surya K. Goli
发明人： Jennifer L. Hillman , Surya K. Goli
IPC分类号： A61K38/00 , C07K14/47 , C12N15/12 , C07K14/435
CPC分类号： C07K14/4702 , A61K38/00
摘要： px19 is an avian gene recently identified as a bromodexoyuridine (BrdU)-sensitive transcript associated with hematopoiesis in early chick development. Its translation product contains an "LEA" (late embryogenesis abundant) motif which had previously been observed only in plant seed proteins. The present invention provides nucleic acids encoding a human LEA motif protein (HuLEAP) homologous to the avian px19 gene product. Also provided are expression vectors, transformed host cells, and methods of using them to produce recombinant HuLEAP polypeptides.
摘要翻译： px19是一种禽类基因，最近被鉴定为与早期小鸡发育中造血作用相关的溴代维甲酸（BrdU）敏感转录物。其翻译产品含有以前仅在植物种子蛋白中观察到的“LEA”（晚期胚胎发生丰富）基序。本发明提供编码与禽类px19基因产物同源的人LEA基序蛋白（HuLEAP）的核酸。还提供了表达载体，转化的宿主细胞和使用它们产生重组HuLEAP多肽的方法。

55. 发明授权

US5856139A Proline-rich acidic protein 失效
标题翻译：脯氨酸丰富的酸性蛋白
公开(公告)号：US5856139A
公开(公告)日：1999-01-05
申请号：US815175
申请日：1997-03-11
申请人： Preeti Lal , Jennifer L. Hillman , Surya K. Goli
发明人： Preeti Lal , Jennifer L. Hillman , Surya K. Goli
IPC分类号： C07K14/47 , C12N15/12 , C12N15/00 , C07H21/04 , C12N1/20 , C12P21/02
CPC分类号： C07K14/47
摘要： The present invention provides a human proline-rich acidic protein (PRAP) and polynucleotides which identify and encode PRAP. In addition, the invention provides expression vectors and host cells, agonists, antibodies, or antagonists. This invention also provides methods for preventing or treating disorders associated with the expression of PRAP.
摘要翻译：本发明提供了富含脯氨酸的酸性蛋白（PRAP）和识别和编码PRAP的多核苷酸。此外，本发明提供表达载体和宿主细胞，激动剂，抗体或拮抗剂。本发明还提供了预防或治疗与PRAP表达相关的疾病的方法。

56. 发明授权

US5856131A Human selenoprotein 失效
公开(公告)号：US5856131A
公开(公告)日：1999-01-05
申请号：US807043
申请日：1997-02-24
申请人： Jennifer L. Hillman , Surya K. Goli
发明人： Jennifer L. Hillman , Surya K. Goli
IPC分类号： A61K38/00 , C07K14/47 , C12P21/06 , C07H21/04 , C12N1/21 , C12N15/63
CPC分类号： C07K14/47 , A61K38/00
摘要： The present invention provides a human selenoprotein (HSEL) and polynucleotides which identify and encode HSEL. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HSEL and a method for producing HSEL. The invention also provides for agonists, antibodies, or antagonists specifically binding HSEL, and their use, in the prevention and treatment of diseases associated with expression of HSEL. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HSEL for the treatment of diseases associated with the expression of HSEL. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HSEL.

57. 发明授权

US5763589A Human membrane protein 失效
标题翻译：人膜蛋白
公开(公告)号：US5763589A
公开(公告)日：1998-06-09
申请号：US781562
申请日：1997-01-09
申请人： Jennifer L. Hillman , Surya K. Goli
发明人： Jennifer L. Hillman , Surya K. Goli
IPC分类号： C07K14/705 , C12N1/21 , C12N15/12 , C07H21/04 , C12N15/63
CPC分类号： C07K14/705
摘要： The present invention provides a novel human integral membrane (IMP) and polynucleotides which identify and encode IMP. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding IMP and a method for producing IMP. The invention also provides for agonists, antibodies, or antagonists specifically binding IMP, and their use, in the prevention and treatment of diseases associated with expression of IMP. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding IMP for the treatment of diseases associated with the expression of IMP. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding IMP.
摘要翻译：本发明提供了一种新型人体内膜（IMP）和识别和编码IMP的多核苷酸。本发明还提供了遗传工程改造的表达载体和宿主细胞，其包含编码IMP的核酸序列和产生IMP的方法。本发明还提供特异性结合IMP的激动剂，抗体或拮抗剂及其在预防和治疗与IMP表达有关的疾病中的用途。另外，本发明提供了反义分子用于编码IMP的多核苷酸用于治疗与IMP表达相关的疾病。本发明还提供利用多核苷酸或其片段或其互补体和特异性结合IMP的抗体的诊断测定法。

58. 发明授权

US06545129B1 Human selenoprotein 失效
标题翻译：人类硒蛋白
公开(公告)号：US06545129B1
公开(公告)日：2003-04-08
申请号：US09393448
申请日：1999-09-10
申请人： Jennifer L. Hillman , Surya K. Goli
发明人： Jennifer L. Hillman , Surya K. Goli
IPC分类号： C07K1600
CPC分类号： C07K14/47 , A61K38/00
摘要： The present invention provides a human selenoprotein (HSEL) and polynucleotides which identify and encode HSEL. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HSEL and a method for producing HSEL. The invention also provides for agonists, antibodies, or antagonists specifically binding, HSEL, and their use, in the prevention and treatment of diseases associated with expression of HSEL. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HSEL for the treatment of diseases associated with the expression of HSEL. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HSEL.
摘要翻译：本发明提供鉴定和编码HSEL的人类硒蛋白（HSEL）和多核苷酸。本发明还提供了遗传工程改造的表达载体和宿主细胞，其包含编码HSEL的核酸序列和生产HSEL的方法。本发明还提供了特异性结合HSEL的激动剂，抗体或拮抗剂及其用于预防和治疗与HSEL表达相关的疾病。另外，本发明提供反义分子用于编码HSEL的多核苷酸用于治疗与HSEL表达相关的疾病。本发明还提供利用多核苷酸或其片段或其补体以及特异性结合HSEL的抗体的诊断测定法。

59. 发明授权

US06248325B1 Glutathione s-transferase 失效
标题翻译：谷胱甘肽转移酶
公开(公告)号：US06248325B1
公开(公告)日：2001-06-19
申请号：US09309320
申请日：1999-05-11
申请人： Surya K. Goli , Jennifer L. Hillman
发明人： Surya K. Goli , Jennifer L. Hillman
IPC分类号： A61K5055
CPC分类号： C12N9/1088 , A61K38/00 , Y10S424/809 , Y10S530/866
摘要： The present invention provides a human glutathione s-transferase (HGST) and polynucleotides which identify and encode HGST. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HGST and a method for producing HGST. The invention also provides for agonists, antibodies, or antagonists specifically binding HGST, and their use, in the prevention and treatment of cancer and other diseases associated with the expression of HGST. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HGST for the treatment of cancer and other diseases associated with the expression of HGST. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HGST.
摘要翻译：本发明提供了人谷胱甘肽转移酶（HGST）和识别和编码HGST的多核苷酸。本发明还提供了遗传工程改造的表达载体和宿主细胞，其包含编码HGST的核酸序列和生产HGST的方法。本发明还提供了特异性结合HGST的激动剂，抗体或拮抗剂及其在预防和治疗与HGST表达相关的癌症和其它疾病中的用途。另外，本发明提供反义分子用于编码HGST的多核苷酸用于治疗与HGST表达相关的癌症和其它疾病。本发明还提供利用多核苷酸或其片段或其补体以及特异性结合HGST的抗体的诊断测定法。

60. 发明授权

US06194385B1 Calcium-binding protein 失效
标题翻译：钙结合蛋白
公开(公告)号：US06194385B1
公开(公告)日：2001-02-27
申请号：US09206499
申请日：1998-12-07
申请人： Jennifer L. Hillman , Surya K. Goli
发明人： Jennifer L. Hillman , Surya K. Goli
IPC分类号： A61K3800
CPC分类号： C07K14/4728 , A61K38/00
摘要： The present invention provides a human calcium-binding protein (HCBP) and polynucleotides which identify and encode HCBP. The invention also provides expression vectors and host cells, agonists, antibodies, and antagonists. In addition, the invention provides methods for producing HCBP and for treating or preventing disorders associated with the expression of HCBP.
摘要翻译：本发明提供了人钙结合蛋白（HCBP）和鉴定和编码HCBP的多核苷酸。本发明还提供表达载体和宿主细胞，激动剂，抗体和拮抗剂。此外，本发明提供了生产HCBP并用于治疗或预防与HCBP表达相关的病症的方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式