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51. 发明授权

US07191017B1 Two-part implantable cardiac lead 有权
标题翻译：两部分可植入心脏铅
公开(公告)号：US07191017B1
公开(公告)日：2007-03-13
申请号：US10888862
申请日：2004-07-09
申请人： Brendan E. Koop , Paul E. Zarembo
发明人： Brendan E. Koop , Paul E. Zarembo
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： A two-part implantable cardiac pacing lead is usable with a cardiac function management device. The lead includes an outer lead portion having a lead body and a conductive coil extending substantially from the proximal end to the distal end. The lead body defines an internal longitudinal lumen. The lead further includes a surface electrode coupled to the lead body near the distal end and a sleeve defining an internal bore. The sleeve mechanically couples to the proximal end of the lead body and is electrically insulated from the conductive coil. The lead further includes an inner lead portion having a pin adapted to mechanically engage the internal bore. The pin is adapted for electrically coupling with a longitudinally-extending conductive member sized to fit within the internal longitudinal lumen.
摘要翻译：两部分植入式心脏起搏引线可用于心脏功能管理装置。引线包括具有引线主体和基本上从近端延伸到远端延伸的导电线圈的外引线部分。引线体定义内部纵向管腔。引线还包括在远端附近耦合到引线本体的表面电极和限定内孔的套管。套筒机械地联接到引线主体的近端并与导电线圈电绝缘。引线还包括具有适于机械地接合内孔的销的内引线部分。该引脚适于与尺寸设计成适合内部纵向内腔的纵向延伸的导电构件电连接。

52. 发明授权

US07072703B2 Medical device with force monitoring features and method therefor 失效
标题翻译：具有力监测功能的医疗装置及其方法
公开(公告)号：US07072703B2
公开(公告)日：2006-07-04
申请号：US10429180
申请日：2003-04-30
申请人： Yongxing Zhang , Paul E. Zarembo , Ronald W. Heil, Jr.
发明人： Yongxing Zhang , Paul E. Zarembo , Ronald W. Heil, Jr.
IPC分类号： A61B5/042 , A61N1/05
CPC分类号： A61B90/06 , A61B2090/064 , A61N1/08
摘要： A medical device for use with an implantable lead includes a force monitoring system coupled with the device. The force monitoring system monitors force placed on the medical device and/or the lead. Optionally the system compares the force with a preset limit, and notifies a user once the preset limit has been reached.
摘要翻译：用于可植入引线的医疗装置包括与该装置耦合的力监测系统。力监测系统监测放在医疗设备和/或引线上的力。可选地，系统将力与预设限制进行比较，一旦达到预设限制，就通知用户。

53. 发明授权

US06912423B2 Terminal connector assembly for a medical device and method therefor 有权
公开(公告)号：US06912423B2
公开(公告)日：2005-06-28
申请号：US10226374
申请日：2002-08-21
申请人： Gregory R. Ley , Gregory L. Sundberg , Jaime L. Rugnetta , Mary S. Wentorf , Paul E. Zarembo , Christopher M. Zerby
发明人： Gregory R. Ley , Gregory L. Sundberg , Jaime L. Rugnetta , Mary S. Wentorf , Paul E. Zarembo , Christopher M. Zerby
IPC分类号： A61N1/05 , A61N1/375 , A61N1/28
CPC分类号： A61N1/056 , A61N1/3752 , H01F2007/1692 , Y10S439/908
摘要： A connector assembly of an electrophysiologial device. The connector assembly includes a substrate forming a tube extending from a proximal end to a distal end an electrical circuit formed on the substrate, such as etching or printing, where the substrate is optionally non-conductive. In another option, the connector assembly includes clad wires and/or flexible circuits within an insulated terminal structure.

54. 发明授权

US08738152B2 Lead assembly including a polymer interconnect and methods related thereto 有权
标题翻译：引线组件，包括聚合物互连和与其相关的方法
公开(公告)号：US08738152B2
公开(公告)日：2014-05-27
申请号：US13724788
申请日：2012-12-21
申请人： Paul E. Zarembo , Elliott Rodriguez Roman
发明人： Paul E. Zarembo , Elliott Rodriguez Roman
IPC分类号： A61N1/00 , A61B5/04
CPC分类号： A61B5/04 , A61N1/04 , A61N1/056 , A61N1/0565 , A61N1/0587 , H01R13/5224 , Y10T29/49172
摘要： A lead assembly includes a ring component having mechanical coupling features, and at least one polymer component mechanically coupled with the mechanical coupling features of the ring component. Elongate tubing is disposed over the polymer component and is secured with the polymer component.
摘要翻译：导线组件包括具有机械耦合特征的环组件和与环组件的机械耦合特征机械耦合的至少一个聚合物组件。细长管被设置在聚合物组分上并用聚合物组分固定。

55. 发明授权

US08285398B2 Lead with terminal connector assembly 有权
标题翻译：带端子连接器总成
公开(公告)号：US08285398B2
公开(公告)日：2012-10-09
申请号：US12831611
申请日：2010-07-07
申请人： Gregory L. Sundberg , Paul E. Zarembo
发明人： Gregory L. Sundberg , Paul E. Zarembo
IPC分类号： A61N1/05
CPC分类号： A61N1/0563 , A61N1/056 , A61N1/0573 , A61N1/3752 , Y10T29/49204 , Y10T29/49208 , Y10T29/49217
摘要： A lead includes a lead body extending from a distal end to a proximal end, and at least one conductor disposed within the lead body and extending from the distal end to the proximal end of the lead body. The lead further includes an outer terminal ring, a terminal pin, and an insulative sleeve disposed between the outer terminal ring and the terminal pin, where the insulative sleeve is coupled with the outer terminal ring with a snap-fit connection. A pin latch is disposed on an outer periphery surface of the insulative sleeve, where the pin latch is rotatable about a hinge point.
摘要翻译：引线包括从远端延伸到近端的引线主体，以及布置在引线主体内并从引线主体的远端延伸到近端的至少一个导体。引线还包括外端子环，端子引脚和设置在外端子环和端子引脚之间的绝缘套管，其中绝缘套管与外端子环以卡扣配合连接。销闩锁设置在绝缘套筒的外周表面上，其中销闩可绕铰链点旋转。

56. 发明申请

US20120136419A1 IMPLANTABLE MEDICAL LEADS WITH SPIRAL LUMENS 审中-公开
标题翻译：具有螺旋体的可植入医用引线
公开(公告)号：US20120136419A1
公开(公告)日：2012-05-31
申请号：US13280445
申请日：2011-10-25
申请人： Paul E. Zarembo , Christopher Hartemink
发明人： Paul E. Zarembo , Christopher Hartemink
IPC分类号： A61N1/05 , B23P19/04
CPC分类号： A61N1/05 , A61N1/0551 , A61N1/056 , H01B7/048 , Y10T29/49838
摘要： An implantable lead may have one or more lumens disposed within a lead body. The lead body may include one or more lumens spirally disposed therein to reduce flex fatigue in regions of frequent flex. The lead body may include one or more spiral lumens and one or more straight lumens.
摘要翻译：可植入引线可以具有设置在引线主体内的一个或多个流明。引线体可以包括螺旋地设置在其中的一个或多个管腔，以减少频繁弯曲的区域中的挠曲疲劳。引线体可以包括一个或多个螺旋流明和一个或多个直管腔。

57. 发明授权

US07920927B2 Lead assembly and methods including a push tube 失效
标题翻译：引线组装和方法，包括推管
公开(公告)号：US07920927B2
公开(公告)日：2011-04-05
申请号：US12163869
申请日：2008-06-27
申请人： Paul E. Zarembo , John Greenland
发明人： Paul E. Zarembo , John Greenland
IPC分类号： A61N1/00
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0578
摘要： A lead assembly includes an elongate body having a conductor electrically coupled with an electrode coupled to the elongate body. The lead assembly includes a push tube extending along at least a portion of the elongate body. A distal tip is coupled to the elongate body substantially adjacent to the distal end of the elongate body. The distal tip is sized and shaped to couple with a push tube distal end. In one option, the distal tip includes a seat to receive the push tube distal end. In another option, the seat is a side rail seat and a guide wire extends along the elongate body and is slidably coupled with the side rail seat. The lead assembly includes, optionally, an active fixation device slidably coupled with a portion of the elongate body, and the active fixation device is sized and shaped to couple with the push tube.
摘要翻译：引线组件包括细长主体，其具有与耦合到细长主体的电极电耦合的导体。引线组件包括沿细长体的至少一部分延伸的推管。远侧末端与细长体联接，基本上与细长体的远端相邻。远侧末端的尺寸和形状与推管远端连接。在一个选择中，远侧末端包括用于接收推管远端的座。在另一种选择中，座椅是侧轨座，导线沿着细长主体延伸并与侧轨座滑动联接。引导组件可选地包括与细长主体的一部分可滑动地联接的主动固定装置，并且主动固定装置的尺寸和形状与推管相连。

58. 发明授权

US07865248B2 Biasing and fixation features on leads 有权
标题翻译：引线上的偏置和固定功能
公开(公告)号：US07865248B2
公开(公告)日：2011-01-04
申请号：US11548838
申请日：2006-10-12
申请人： Paul E. Zarembo , Brian D. Soltis
发明人： Paul E. Zarembo , Brian D. Soltis
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead assembly for placement in a coronary vessel of the heart, the coronary vessel having a pericardial wall portion and a myocardial wall portion. The lead assembly comprises a lead body extending from a proximal end adapted for coupling to a pulse generator to a distal end adapted for implantation in the heart, an electrode positioned at the distal end of the lead body, and a loop biasing feature located at the distal end of the lead body. The loop biasing feature includes a resilient loop positioned to bias a portion of the electrode towards the myocardial wall portion of the coronary vessel by exerting a force against the pericardial wall portion. The loop biasing feature further includes a collar for coupling the loop biasing feature to the lead body. A method of implanting the lead assembly.
摘要翻译：用于放置在心脏的冠状血管中的引导组件，所述冠状血管具有心包壁部分和心肌壁部分。引线组件包括引线本体，其从适于联接到脉冲发生器的近端延伸到适于植入心脏的远端，位于引线主体的远端的电极以及位于引线主体的环偏置特征引线体的远端。环偏置特征包括弹性环，其定位成通过向心包壁部分施加力而将电极的一部分朝向冠状血管的心肌壁部分偏置。环偏置特征还包括用于将环偏置特征耦合到引线体的套环。一种植入引线组件的方法。

59. 发明申请

US20100228263A1 LEAD ASSEMBLY AND METHODS INCLUDING A PUSH TUBE 失效
标题翻译：引导组件和包括推管的方法
公开(公告)号：US20100228263A1
公开(公告)日：2010-09-09
申请号：US12785929
申请日：2010-05-24
申请人： Paul E. Zarembo , John S. Greenland
发明人： Paul E. Zarembo , John S. Greenland
IPC分类号： A61B17/00
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0578
摘要： A lead assembly includes an elongate body having a conductor electrically coupled with an electrode coupled to the elongate body. The lead assembly includes a push tube extending along at least a portion of the elongate body. A distal tip is coupled to the elongate body substantially adjacent to the distal end of the elongate body. The distal tip is sized and shaped to couple with a push tube distal end. In one option, the distal tip includes a seat to receive the push tube distal end. In another option, the seat is a side rail seat and a guide wire extends along the elongate body and is slidably coupled with the side rail seat. The lead assembly includes, optionally, an active fixation device slidably coupled with a portion of the elongate body, and the active fixation device is sized and shaped to couple with the push tube.
摘要翻译：引线组件包括细长主体，其具有与耦合到细长主体的电极电耦合的导体。引线组件包括沿细长体的至少一部分延伸的推管。远侧末端与细长体联接，基本上与细长体的远端相邻。远侧末端的尺寸和形状与推管远端连接。在一个选择中，远侧末端包括用于接收推管远端的座。在另一种选择中，座椅是侧轨座，导线沿着细长主体延伸并与侧轨座滑动联接。引导组件可选地包括与细长主体的一部分可滑动地联接的主动固定装置，并且主动固定装置的尺寸和形状与推管相连。

60. 发明授权

US07672735B2 Two-part implantable cardiac lead 失效
标题翻译：两部分可植入心脏铅
公开(公告)号：US07672735B2
公开(公告)日：2010-03-02
申请号：US11346096
申请日：2006-02-02
申请人： Brendan E. Koop , Paul E. Zarembo
发明人： Brendan E. Koop , Paul E. Zarembo
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： Methods of implanting a two-part cardiac lead in a heart are disclosed. The two-part cardiac lead has inner and outer portions and a pin. The inner and outer lead portions are separately advanced to a location of interest within the vasculature of a patient. The pin is attached to a proximal end of the inner lead portion and can provide a connection between the inner and outer lead portions.
摘要翻译：公开了将两部分心脏铅引入心脏的方法。两部分心脏引线具有内部和外部部分以及引脚。内部和外部引线部分分别前进到患者脉管系统内的感兴趣位置。销固定在内引导部分的近端上，并且可以在内引线部分和外引线部分之间提供连接。

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