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51. 发明申请

US20090318956A1 Wire-Like And Other Devices For Treating Septal Defects And Systems And Methods For Delivering The Same 审中-公开
标题翻译：线状和其他设备用于治疗间隔缺损和系统及其提供方法
公开(公告)号：US20090318956A1
公开(公告)日：2009-12-24
申请号：US12469466
申请日：2009-05-20
申请人： W. Martin Belef , Dean Carson , Ronald J. Jabba , Anthony J. Pantages , Taylor A. Heanue
发明人： W. Martin Belef , Dean Carson , Ronald J. Jabba , Anthony J. Pantages , Taylor A. Heanue
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606
摘要： Systems, devices and methods for treating internal tissue defects, such as septal defects, with implantable devices are provided. In some exemplary embodiments, these devices include one or more wires coupled together. The device can include deflectable anchors for engaging the septal tissue.
摘要翻译：提供了用可植入装置来治疗内部组织缺陷如间隔缺损的系统，装置和方法。在一些示例性实施例中，这些设备包括耦合在一起的一个或多个导线。该装置可以包括用于接合隔膜组织的可偏转锚。

52. 发明申请

US20090036923A1 Systems and methods for accommodating anatomical characteristics in the treatment of septal defects 审中-公开
标题翻译：用于治疗间隔缺损的解剖特征的系统和方法
公开(公告)号：US20090036923A1
公开(公告)日：2009-02-05
申请号：US12113842
申请日：2008-05-01
申请人： Ronald J. Jabba , Ryan Abbott , Dean Carson , James Nielsen , W. Martin Belef
发明人： Ronald J. Jabba , Ryan Abbott , Dean Carson , James Nielsen , W. Martin Belef
IPC分类号： A61B17/04
CPC分类号： A61B17/3468 , A61B17/00234 , A61B17/0057 , A61B17/0644 , A61B17/083 , A61B2017/00243 , A61B2017/00575 , A61B2017/00606 , A61B2017/00623 , A61B2017/2926
摘要： Systems and methods for treating internal tissue defects, such as septal defects, with implantable devices are provided. An exemplary clip-based device includes a tubular body having at least a deflectable anchors coupled thereto. The anchors can be coupled on opposite ends of the tubular body and configured to deflect between an undeployed configuration and a deployed configuration. In the deployed configuration, each anchor extends outwardly away from the tubular body in a position configured to abut a tissue surface. The anchors are preferably configured to maintain a tissue wall therebetween and at least partially close any opening in the tissue wall. Also provided are delivery devices for delivering the implantable closure device and methods for using the various devices.
摘要翻译：提供了用可植入装置处理内部组织缺陷如间隔缺损的系统和方法。示例性的基于夹片的装置包括具有至少可耦合到其上的可偏转锚定件的管状主体。锚固件可以联接在管状主体的相对端上，并且构造成在未部署构型和展开配置之间发生偏转。在所展开的构造中，每个锚定件在构造成邻接组织表面的位置处向外远离管状体延伸。锚固件优选地构造成在其间保持组织壁并且至少部分地关闭组织壁中的任何开口。还提供了用于递送可植入闭合装置的递送装置和使用各种装置的方法。

53. 发明授权

US06770035B2 Ultrasound imaging guidewire with static central core and tip 失效
标题翻译：超声成像导丝带静电中心芯和尖端
公开(公告)号：US06770035B2
公开(公告)日：2004-08-03
申请号：US10405586
申请日：2003-04-01
申请人： David A. White , W. Martin Belef
发明人： David A. White , W. Martin Belef
IPC分类号： A61B814
CPC分类号： A61B8/12 , A61B8/4461 , A61M25/09
摘要： An ultrasound imaging guidewire, that is inserted into a patient's body. The guidewire has a static central core and an imaging guidewire body comprising an acoustical scanning device. The acoustical scanning device can be rotated to obtain 360 degree acoustical images of a site of interest in the patients body. Furthermore, the imaging guidewire includes a connector that permits the imaging guidewire body to be disengaged from the static central core tip so that the imaging guidewire body can be axially translated to obtain multi-position imaging. The imaging guidewire body is axially translated without losing the original guidewire positioning because the static central core maintains its position in the patient's body.
摘要翻译：超声成像导丝，其被插入患者体内。引导线具有静电中心芯和包括声学扫描装置的成像导丝主体。可以旋转声学扫描装置以获得患者身体中感兴趣的部位的360度声学图像。此外，成像引导线包括允许成像导丝主体从静态中心芯尖脱离的连接器，使得成像导丝主体可以被轴向平移以获得多位置成像。成像导丝主体轴向平移而不会损失原始的导丝定位，因为静态中心芯保持其在患者体内的位置。

54. 发明申请

US20120046688A1 Clip-Based Systems and Methods for Treating Septal Defects 审中-公开
标题翻译：基于夹层的系统和治疗间隔缺损的方法
公开(公告)号：US20120046688A1
公开(公告)日：2012-02-23
申请号：US13283969
申请日：2011-10-28
申请人： Ryan Abbott , W. Martin Belef , Dean Carson , Peter Fitzgerald , Ronald J. Jabba , James Nielsen , Peter Thornton
发明人： Ryan Abbott , W. Martin Belef , Dean Carson , Peter Fitzgerald , Ronald J. Jabba , James Nielsen , Peter Thornton
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/12122 , A61B17/221 , A61B2017/00247 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00606 , A61B2017/00615 , A61B2017/00619 , A61B2017/00623 , A61B2017/00867 , A61B2017/00893 , A61B2017/0412 , A61B2017/0419 , A61B2017/0422 , A61B2017/22047 , A61B2017/2926 , A61B2017/306 , A61B2018/00392
摘要： Systems and methods for treating internal tissue defects, such as septal defects, with clip-based devices are provided. An exemplary clip-based device includes a tubular body having at least a first and a second deflectable member coupled thereto. The first and second members are coupled on opposite ends of the tubular body and configured to deflect between an undeployed configuration and a deployed configuration. In the deployed configuration, each member extends outwardly away from the tubular body in a position configured to abut a tissue surface. The first and second members are preferably configured to maintain a tissue wall therebetween and at least partially close any opening in the tissue wall.
摘要翻译：提供了用于基于夹子的装置来治疗内部组织缺陷（例如间隔缺损）的系统和方法。示例性的基于夹子的装置包括具有与其连接的至少第一和第二可偏转构件的管状体。第一和第二构件联接在管状体的相对端部并且构造成在未部署构造和展开配置之间偏转。在所展开的构造中，每个构件在构造成邻接组织表面的位置中向外远离管状体延伸。第一和第二构件优选地构造成在其间保持组织壁并且至少部分地关闭组织壁中的任何开口。

55. 发明申请

US20110093007A1 SYSTEMS AND METHODS FOR TREATING SEPTAL DEFECTS 失效
标题翻译：用于处理缺陷的系统和方法
公开(公告)号：US20110093007A1
公开(公告)日：2011-04-21
申请号：US12819911
申请日：2010-06-21
申请人： Ryan Abbott , W. Martin Belef , Dean Carson , Taylor A. Heanue , Ronald J. Jabba , Anthony J. Pantages
发明人： Ryan Abbott , W. Martin Belef , Dean Carson , Taylor A. Heanue , Ronald J. Jabba , Anthony J. Pantages
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B5/0215 , A61B5/415 , A61B5/418 , A61B17/0644 , A61B17/068 , A61B17/29 , A61B2017/00243 , A61B2017/00292 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61B2017/00867 , A61B2017/061 , A61B2017/0649 , A61B2017/22047 , A61B2017/2912 , A61B2090/0811 , A61F2002/9517
摘要： A system for treating a septal defect having an implantable treatment apparatus and devices for delivering the implantable treatment apparatus, devices for controlling delivery of the treatment apparatus and methods for treating a septal defect are provided. The implantable treatment apparatus is preferably implantable through a septal wall or portion thereof. The treatment system can include a flexible elongate body member, a delivery device configured to deliver the implantable apparatus, and a proximal control device for controlling delivery of the implantable apparatus, among others.
摘要翻译：提供一种用于治疗具有可植入治疗装置的间隔缺损的系统和用于递送可植入治疗装置的装置，用于控制治疗装置的输送的装置和用于治疗间隔缺损的方法。可植入治疗装置优选通过中隔壁或其部分植入。治疗系统可以包括柔性细长主体构件，配置成输送可植入装置的输送装置，以及用于控制可植入装置的输送的近端控制装置等。

56. 发明申请

US20100234879A1 Systems and Methods for Treating Septal Defects 审中-公开
标题翻译：系统和方法治疗间隔缺损
公开(公告)号：US20100234879A1
公开(公告)日：2010-09-16
申请号：US12725282
申请日：2010-03-16
申请人： Ryan Abbott , W. Martin Belef , Dean Carson , Rajiv Doshi , Ronald J. Jabba
发明人： Ryan Abbott , W. Martin Belef , Dean Carson , Rajiv Doshi , Ronald J. Jabba
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B17/064 , A61B17/221 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61B2017/00867 , A61B2017/0649 , A61B2017/22047 , A61B2017/2926 , A61B2017/306
摘要： A system for treating a septal defect having an implantable treatment apparatus and devices for delivering the implantable treatment apparatus and methods for treating a septal defect are provided. The implantable treatment apparatus is preferably implantable through a septal wall or portion thereof. The treatment system can include a flexible elongate body member, a delivery device configured to deliver the implantable apparatus, a stabilization device configured to stabilize the body member and a positioning device configured to position the delivery device in a desired location.
摘要翻译：提供了一种用于治疗具有可植入治疗装置的间隔缺损的系统和用于递送可植入治疗装置的装置和用于治疗间隔缺损的方法。可植入治疗装置优选通过中隔壁或其部分植入。治疗系统可以包括柔性细长主体构件，配置成输送可植入装置的输送装置，被配置为使身体构件稳定的稳定装置和构造成将输送装置定位在期望位置的定位装置。

57. 发明授权

US07686828B2 Systems and methods for treating septal defects 失效
标题翻译：用于治疗间隔缺损的系统和方法
公开(公告)号：US07686828B2
公开(公告)日：2010-03-30
申请号：US11422871
申请日：2006-06-07
申请人： Ryan Abbott , W. Martin Belef , Dean Carson , Rajiv Doshi , Ronald J. Jabba
发明人： Ryan Abbott , W. Martin Belef , Dean Carson , Rajiv Doshi , Ronald J. Jabba
IPC分类号： A61B17/08 , A61D1/00
CPC分类号： A61B17/0057 , A61B17/064 , A61B17/221 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61B2017/00867 , A61B2017/0649 , A61B2017/22047 , A61B2017/2926 , A61B2017/306
摘要： A system for treating a septal defect having an implantable treatment apparatus and devices for delivering the implantable treatment apparatus and methods for treating a septal defect are provided. The implantable treatment apparatus is preferably implantable through a septal wall or portion thereof. The treatment system can include a flexible elongate body member, a delivery device configured to deliver the implantable apparatus, a stabilization device configured to stabilize the body member and a positioning device configured to position the delivery device in a desired location.
摘要翻译：提供了一种用于治疗具有可植入治疗装置的间隔缺损的系统和用于递送可植入治疗装置的装置和用于治疗间隔缺损的方法。可植入治疗装置优选通过中隔壁或其部分植入。治疗系统可以包括柔性细长主体构件，配置成输送可植入装置的输送装置，被配置为使身体构件稳定的稳定装置和构造成将输送装置定位在期望位置的定位装置。

58. 发明申请

US20080154286A1 Systems and Methods for Treating Septal Defects with Capture Devices and Other Devices 审中-公开
标题翻译：用捕获设备和其他设备治疗间隔缺损的系统和方法
公开(公告)号：US20080154286A1
公开(公告)日：2008-06-26
申请号：US11614814
申请日：2006-12-21
申请人： Ryan Abbott , W. Martin Belef , Dean Carson , Ronald J. Jabba , David Moore , James Nielsen
发明人： Ryan Abbott , W. Martin Belef , Dean Carson , Ronald J. Jabba , David Moore , James Nielsen
IPC分类号： A61B17/04
CPC分类号： A61B17/0487 , A61B17/0401 , A61B17/0467 , A61B17/0469 , A61B17/0483 , A61B17/0485 , A61B17/0625 , A61B2017/00477 , A61B2017/00867 , A61B2017/0404 , A61B2017/0456 , A61B2017/0458 , A61B2017/0472 , A61B2017/0608 , A61B2017/06095 , A61B2017/06176
摘要： Systems, devices and methods for treating internal tissue defects, such as septal defects, are provided. An exemplary method of treating an internal tissue defect, specifically a method of closing a patent foramen ovale (PFO), can include passing a closure element from a right atrium through a septal wall in a first location and into the left atrium. A capture device, which can be configured as a snare-like device, can be used to capture the closure element in the left atrium and pull the closure element back through the septal wall in a different, second location, such that the closure element is routed over the PFO. The closure element can then be anchored and/or locked against the septal wall such that the PFO is at least partially closed.
摘要翻译：提供了用于治疗内部组织缺陷的系统，装置和方法，例如间隔缺损。治疗内部组织缺陷的具体方法，特别是关闭卵圆孔卵泡（PFO）的方法，可以包括将闭合元件从右心房通过第一位置的隔壁并进入左心房。捕获装置可被配置为圈套状装置，可用于捕获左心房中的闭合元件，并将闭合元件通过间隔壁在不同的第二位置向后拉动，使得闭合元件为通过PFO路由。闭合元件然后可以锚定和/或锁定在隔壁上，使得PFO至少部分地封闭。

59. 发明授权

US07169165B2 Rapid exchange sheath for deployment of medical devices and methods of use 有权
标题翻译：用于部署医疗器械的快速交换护套和使用方法
公开(公告)号：US07169165B2
公开(公告)日：2007-01-30
申请号：US10039214
申请日：2002-01-04
申请人： W. Martin Belef , Ross S. Tsugita
发明人： W. Martin Belef , Ross S. Tsugita
IPC分类号： A61M29/00
CPC分类号： A61B17/221 , A61F2/013 , A61F2/958 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0093 , A61M25/0169 , A61M25/0172 , A61M25/0662 , A61M25/104 , A61M2025/018 , A61M2025/0183
摘要： A rapid exchange sheath comprising an elongate tubular member, a guidewire, and support wire having an expandable filter at a distal end. The guidewire passes through a first opening at a distal end of the tubular member and a second opening a short distance proximal from the distal end. The support wire is received in a lumen of the tubular member, or, in certain embodiments, extends proximally through a third opening a short distance proximal from the distal end. Methods of using the sheaths for deploying and/or exchanging medical device(s) in a patient's vessel are also disclosed.
摘要翻译：一种快速交换护套，其包括细长管状构件，导丝和在远端具有可扩张过滤器的支撑线。导丝穿过管状构件的远端处的第一开口和远离近端的短距离的第二开口。支撑线被容纳在管状构件的内腔中，或者在某些实施例中，近端延伸通过距离远端近的短距离的第三开口。还公开了在病人血管中使用用于部署和/或交换医疗装置的护套的方法。

60. 发明授权

US06936059B2 Endovascular guidewire filter and methods of use 有权
标题翻译：血管内导丝过滤器及使用方法
公开(公告)号：US06936059B2
公开(公告)日：2005-08-30
申请号：US10039102
申请日：2002-01-04
申请人： W. Martin Belef
发明人： W. Martin Belef
IPC分类号： A61B17/00 , A61F2/01 , A61M29/00
CPC分类号： A61F2/013 , A61F2002/011 , A61F2002/018 , A61F2230/0006 , A61F2230/008
摘要： A filter device for temporary placement of a filter in an artery or vein is disclosed. The devices include (1) an elongate tubular member having a single or double side-wire loop, (2) an elongate member having a filter bonded to a circular rim joined by a plurality of tethers and an independently moveable tether, and (3) an elongate member having a parachute filter joined by a plurality of flexible struts. The filter conforms to the interior of a vessel wall when expanded and contracts to a consistent diameter without bunching when stowed. The filter devices may act as guidewires for guiding a therapeutic catheter to a region of interest within a vessel. Methods of using the filter device to entrap and remove embolic material from a vessel during endovascular procedures are also disclosed.
摘要翻译：公开了一种用于将过滤器临时放置在动脉或静脉中的过滤装置。这些装置包括（1）具有单侧或双侧线路环的细长管状构件，（2）细长构件，其具有结合到由多个系绳连接的圆形边缘的过滤器和独立可移动的系绳，以及（3）具有通过多个柔性支柱连接的降落伞过滤器的细长构件。过滤器在膨胀时符合血管壁的内部，并收缩到一致的直径，而不会在收起时聚束。过滤器装置可以用作导线，用于将治疗导管引导到血管内的感兴趣区域。还公开了使用过滤装置在血管内手术期间从血管中捕获和去除栓塞物质的方法。

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