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51. 发明授权

US4769433A High strength polyolefins 失效
标题翻译：高强度聚烯烃
公开(公告)号：US4769433A
公开(公告)日：1988-09-06
申请号：US901768
申请日：1986-08-29
申请人： Henri D. Chanzy , Bruno Rotzinger , Paul Smith
发明人： Henri D. Chanzy , Bruno Rotzinger , Paul Smith
IPC分类号： C08F10/00 , B29C43/00 , B29C47/00 , B29C67/24 , B29K23/00 , C08F2/00 , C08F2/12 , C08F4/60 , C08F4/639 , C08F4/68 , C08F8/00 , C08J5/18 , C08L23/06 , D01F6/04 , C08F10/02 , D02J1/22
CPC分类号： C08J5/18 , B29C47/0004 , B29C67/24 , C08F2/12 , C08L23/06 , D01F6/04 , B29C47/00 , B29C47/0014 , B29C47/0021 , B29K2023/0683 , B29K2995/0088 , C08J2323/06
摘要： High strength, substantially linear, highly crystalline, high molecular weight-polyolefin shaped structure having a tenacity of greater than 15 g/den and an initial modulus of greater than 500 g/den by drawing never-processed polyolefin at a temperature of 60.degree. C. to 145.degree. C.; and processes for making never-processed polyolefin and such shaped structures.
摘要翻译：高强度，基本线性，高结晶，高分子量 - 聚烯烃形结构，其强度大于15g / l，初始模量大于500g / 145℃。以及用于制造未经处理的聚烯烃和这种成形结构的方法。

52. 发明授权

US4436689A Process for the production of polymer filaments having high tensile strength 失效
标题翻译：生产具有高拉伸强度的聚合物长丝的方法
公开(公告)号：US4436689A
公开(公告)日：1984-03-13
申请号：US434829
申请日：1982-10-18
申请人： Paul Smith , Pieter J. Lemstra , Robert Kirschbaum , Jacques P. L. Pijpers
发明人： Paul Smith , Pieter J. Lemstra , Robert Kirschbaum , Jacques P. L. Pijpers
IPC分类号： D01D5/04 , D01F6/04 , D01F6/00
CPC分类号： D01F6/04 , D01D5/04
摘要： An improved process for the preparation of polymer filaments having a high tensile strength and modulus by spinning a solution of high-molecular weight polymer and thereafter stretching the filament thus formed. A solution of an ethylene polymer or copolymer, containing at least 80 percent by weight solvent, is spun at a temperature above the gel point of the solution. The ethylene polymer or copolymer contains at most about 5 percent by weight of an alkene having 3 to 8 carbon atoms, has a weight-average molecular weight Mw higher than 4.times.10.sup.5 kg/kmole, and has a weight/number average molecular weight ratio Mw/Mn lower than 5. The spun polymer solution is thereafter cooled to a temperature below its gel point to form a gel filament, which gel filament is thereafter stretched to form a polymer filament having a tensile strength of at least about 1.5 GPa at room temperature.
摘要翻译：通过旋转高分子量聚合物溶液，然后拉伸如此形成的长丝，制备具有高拉伸强度和模量的聚合物长丝的改进方法。含有至少80重量％溶剂的乙烯聚合物或共聚物的溶液在高于溶液凝胶点的温度下纺丝。乙烯聚合物或共聚物含有至多约5重量％的具有3至8个碳原子的烯烃，重均分子量Mw高于4×10 5 kg / kmole，并且具有重量/数均分子量Mw / Mn低于5.然后将纺丝聚合物溶液冷却至低于其凝胶点的温度以形成凝胶长丝，然后将该凝胶长丝拉伸以形成室温下拉伸强度为至少约1.5GPa的聚合物长丝。

53. 发明授权

US4344908A Process for making polymer filaments which have a high tensile strength and a high modulus 失效
标题翻译：具有高拉伸强度和高模量的制备聚合物长丝的方法
公开(公告)号：US4344908A
公开(公告)日：1982-08-17
申请号：US119045
申请日：1980-02-06
申请人： Paul Smith , Pieter J. Lemstra
发明人： Paul Smith , Pieter J. Lemstra
IPC分类号： B29C70/10 , D01F6/04 , D01F6/00
CPC分类号： D01F6/04 , B29C70/10 , D01D10/02 , D01D5/12 , B29K2105/08 , B29K2223/06 , B29K2995/0088 , D07B1/025 , D07B2205/2014 , Y10T428/2913
摘要： A process for making polymer filaments which have a high tensile strength and a high modulus by stretching a polymer filament which contains an appreciable amount of polymer solvent at a temperature between the swelling point and the melting point of the polymer.
摘要翻译：通过在聚合物的溶胀点和熔点之间的温度下拉伸含有相当量的聚合物溶剂的聚合物长丝，制备具有高拉伸强度和高模量的聚合物长丝的方法。

54. 发明授权

US4327228A 3-Nitro-1-phenyl-1-(m-chlorophenyl)-propan-2-ol. 失效
标题翻译： 3-硝基-1-苯基-1-（间氯苯基） - 丙-2-醇。
公开(公告)号：US4327228A
公开(公告)日：1982-04-27
申请号：US156189
申请日：1980-06-03
申请人： Paul Smith
发明人： Paul Smith
IPC分类号： C07C215/28 , C07C67/00 , C07C201/00 , C07C205/16 , C07C205/26 , C07C213/00 , C07C4/00
CPC分类号： C07C205/26
摘要： A process for the preparation of 3-dimethylamino-1-phenyl-(m-chlorophenyl)propan-2-ol and its salts which comprises the Raney nickel catalysed reduction of 3-nitro-1-phenyl-(1-m-chlorophenyl)propan-2-ol with simultaneous or subsequent dimethylation and thereafter, if desired, salification.
摘要翻译：一种制备3-二甲基氨基-1-苯基 - （间氯苯基）丙-2-醇及其盐的方法，其包括阮内镍催化还原3-硝基-1-苯基 - （1-间氯苯基）丙-2-醇，同时或随后的二甲基化，然后如果需要，成盐。

55. 发明申请

US20210299487A1 DO IT YOURSELF (DIY) RESPIRATION AND VENTILATION SYSTEMS AND METHODS 有权
公开(公告)号：US20210299487A1
公开(公告)日：2021-09-30
申请号：US17216336
申请日：2021-03-29
申请人： Mark English , Carlos R. Villamar , Paul Smith
发明人： Mark English , Carlos R. Villamar , Paul Smith
IPC分类号： A62B18/02 , A62B7/10
摘要： A system, method and computer program product for a do-it-yourself (DIY) system for assisted respirators, including a full-face snorkel mask with snorkel connection; a hose having a first end connected to the snorkel connection of the mask; a blower connected a second end of the hose; and a portable power supply powering the blower. The blower includes a HEPA level filter on an air input thereof, and the blower pumps HEPA filtered air through the hose into the mask.

56. 发明授权

US09759715B2 Gel formulations and uses thereof 有权
公开(公告)号：US09759715B2
公开(公告)日：2017-09-12
申请号：US12749056
申请日：2010-03-29
申请人： Paul Smith , Laurence Patterson , Rachel Jane Errington
发明人： Paul Smith , Laurence Patterson , Rachel Jane Errington
IPC分类号： B01L3/00 , G01N33/50 , A61L31/14 , C11D3/37 , G01N21/27 , G01N21/64 , G01N33/545
CPC分类号： G01N33/5005 , A61L31/145 , C11D3/3707 , G01N21/274 , G01N21/278 , G01N21/6458 , G01N33/545 , Y02A50/58
摘要： The present invention provides the use of a composition comprising a block polymer as a support matrix in the manipulation, processing or analysis of particles, such as cells and fluorescent beads. In a preferred embodiment, the composition exhibits gel-sol thermoreversibility, micelle formation under gelling conditions, optically compatible, controllable surfactant properties, molecular sieving properties and biocompatibility. Further aspects of the invention provide (a) a support matrix composition comprising a block polymer, fluorescent beads and/or a dye for use in the manipulation, processing or analysis of particles, (b) a multichamber plate coated in a support matrix composition and (c) kits for producing the same.

57. 发明授权

US09629647B2 Adjustable resection device and related methods of use 有权
公开(公告)号：US09629647B2
公开(公告)日：2017-04-25
申请号：US13727345
申请日：2012-12-26
申请人： Paul Smith , Samuel Raybin
发明人： Paul Smith , Samuel Raybin
IPC分类号： A61B1/00 , A61B17/32 , A61B17/00 , A61B17/30 , A61B90/00
CPC分类号： A61B17/00234 , A61B1/00087 , A61B1/00089 , A61B1/015 , A61B1/05 , A61B1/0676 , A61B17/30 , A61B17/320016 , A61B17/3205 , A61B90/39 , A61B2017/00269 , A61B2017/00336 , A61B2017/00818 , A61B2017/306 , A61B2090/033 , A61B2090/3966
摘要： A medical device and related method of use for resecting a tissue. The medical device may include an elongate member having a proximal end, a distal end, and a lumen extending therebetween. The elongate member may include a distal portion defining a cavity having an opening. In addition, a mechanism may be configured to adjust a volume of the cavity by altering a depth of the cavity.

58. 发明授权

US09463059B2 Cutting tool with circulating wire 有权
标题翻译：切割工具带循环丝
公开(公告)号：US09463059B2
公开(公告)日：2016-10-11
申请号：US13763220
申请日：2013-02-08
申请人： Naroun Suon , Ra Nam , Samuel Raybin , Paul Smith , Jonathan Root
发明人： Naroun Suon , Ra Nam , Samuel Raybin , Paul Smith , Jonathan Root
IPC分类号： A61B17/26 , A61B18/14 , A61B18/04 , A61B17/32 , A61B18/00 , A61B17/00
CPC分类号： A61B18/04 , A61B17/32 , A61B18/1485 , A61B18/149 , A61B18/1492 , A61B2017/00269 , A61B2018/00184 , A61B2018/1407 , A61B2018/141 , A61B2018/144 , A61B2018/1475
摘要： A medical device and related method of use for cutting tissue is described. The device includes an elongate tubular member having a proximal end, a distal end, and first and second lumens extending between the proximal and distal ends. The device further includes a first elongate arm having a third lumen extending distally from the first lumen and a second elongate arm having a fourth lumen extending distally from the second lumen. A cutting element extends from the third lumen of the first arm to the fourth lumen of the second arm, such that the cutting element is slidably disposed in at least one of the third and fourth lumens.
摘要翻译：描述了用于切割组织的医疗装置和相关的使用方法。该装置包括具有近端，远端以及在近端和远端之间延伸的第一和第二腔的细长管状构件。该装置还包括具有从第一内腔向远侧延伸的第三腔的第一细长臂和具有从第二腔向远侧延伸的第四腔的第二细长臂。切割元件从第一臂的第三腔延伸到第二臂的第四腔，使得切割元件可滑动地设置在第三和第四腔中的至少一个腔中。

59. 发明授权

US09173671B2 Tissue resection device and related methods of use 有权
标题翻译：组织切除装置及相关使用方法
公开(公告)号：US09173671B2
公开(公告)日：2015-11-03
申请号：US13728078
申请日：2012-12-27
申请人： Paul Smith , Samuel Raybin , Naroun Suon , Gary Kappel
发明人： Paul Smith , Samuel Raybin , Naroun Suon , Gary Kappel
IPC分类号： A61B17/32 , A61B17/3205 , A61B17/00 , A61B18/00 , A61B17/30 , A61B18/14
CPC分类号： A61B17/320016 , A61B17/32 , A61B17/32056 , A61B18/00 , A61B18/1492 , A61B2017/00269 , A61B2017/003 , A61B2017/306 , A61B2018/141
摘要： A device configured to facilitate resection of tissue. The device may include a proximal end configured to be secured to a distal portion of an introduction sheath and a distal end defining an opening that may communicate with a channel extending between the proximal and distal ends. The opening may be defined by at least one straight edge.
摘要翻译：被配置为便于切除组织的装置。该装置可以包括被配置为固定到引入护套的远侧部分的近端和限定可在近端和远端之间延伸的通道连通的开口的远端。开口可以由至少一个直边限定。

60. 发明授权

US09011434B2 Multi-functional medical device and related methods of use 有权
标题翻译：多功能医疗器械及相关使用方法
公开(公告)号：US09011434B2
公开(公告)日：2015-04-21
申请号：US13755579
申请日：2013-01-31
申请人： Gary Kappel , Sean Fleury , Paul Smith , Brandon Zalewski , Laurie Soderborn
发明人： Gary Kappel , Sean Fleury , Paul Smith , Brandon Zalewski , Laurie Soderborn
IPC分类号： A61B18/18 , A61B17/29 , A61B17/295 , A61B18/08 , A61B17/32 , A61B19/00 , A61B18/14
CPC分类号： A61B17/295 , A61B17/068 , A61B17/29 , A61B17/34 , A61B18/085 , A61B18/1445 , A61B2017/2901 , A61B2017/2926 , A61B2017/320044 , A61B2018/00595 , A61B2018/1455 , A61B2090/0817 , A61B2217/005 , A61B2217/007 , A61B2218/002 , A61B2218/007
摘要： A medical device including an elongate member having a proximal end, a distal end, and a lumen extending therebetween. The medical device may further include an end-effector disposed at the distal end of the elongate member. The end-effector may include a plurality of arms pivotally connected to one another, wherein each arm includes a tissue-contacting surface, a first portion of the tissue-contacting surface including a plurality of ridges configured to grasp tissue. Further, the tissue-contacting surface may include a channel oriented substantially parallel to a longitudinal axis of the medical device.
摘要翻译：一种医疗装置，包括具有近端，远端和在其间延伸的内腔的细长构件。医疗装置还可以包括设置在细长构件的远端处的末端执行器。末端执行器可以包括彼此枢转地连接的多个臂，其中每个臂包括组织接触表面，组织接触表面的第一部分包括构造成抓住组织的多个脊。此外，组织接触表面可以包括基本上平行于医疗装置的纵向轴线定向的通道。

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