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51. 发明申请

US20140275879A1 SYSTEMS AND METHODS FOR DETERMINING RESPIRATION INFORMATION BASED ON INDEPENDENT COMPONENT ANALYSIS 审中-公开
标题翻译：基于独立分量分析确定呼叫信息的系统和方法
公开(公告)号：US20140275879A1
公开(公告)日：2014-09-18
申请号：US13842625
申请日：2013-03-15
申请人： Paul Stanley Addison , James Nicholas Watson , Jimmy Dripps , James Ochs
发明人： Paul Stanley Addison , James Nicholas Watson , Jimmy Dripps , James Ochs
IPC分类号： A61B5/00 , A61B5/1455
CPC分类号： A61B5/7246 , A61B5/0295 , A61B5/0816 , A61B5/0876 , A61B5/14551 , A61B5/7235
摘要： A patient monitoring system may receive a physiological signal such as a photoplethysmograph (PPG) signal. A plurality of respiration morphology signals may be determined from the PPG signal. Independent component analysis may be performed on the respiration morphology signals, resulting in a plurality of independent components. An independent component corresponding to a respiration source signal may be selected from the plurality of independent components. Respiration information such as respiration rate may be determined based at least in part on the selected independent component.
摘要翻译：病人监护系统可以接收生理信号，例如光电体积描记器（PPG）信号。可以从PPG信号确定多个呼吸形态信号。可以对呼吸形态信号执行独立分量分析，从而产生多个独立分量。可以从多个独立分量中选择对应于呼吸源信号的独立分量。呼吸信息如呼吸速率可以至少部分地基于所选择的独立组件来确定。

52. 发明授权

US08761855B2 Systems and methods for determining oxygen saturation 有权
标题翻译：用于确定氧饱和度的系统和方法
公开(公告)号：US08761855B2
公开(公告)日：2014-06-24
申请号：US12249068
申请日：2008-10-10
申请人： James Nicholas Watson , Paul Stanley Addison
发明人： James Nicholas Watson , Paul Stanley Addison
IPC分类号： A61B5/00
CPC分类号： A61B5/14551 , A61B5/7203 , A61B5/7257 , A61B5/726 , A61B5/742
摘要： According to embodiments, techniques for using continuous wavelet transforms and spectral transforms to determine oxygen saturation from photoplethysmographic (PPG) signals are disclosed. According to embodiments, a first oxygen saturation may be determined from wavelet transformed PPG signals and a second oxygen saturation may be determined from spectral transformed PPG signals. An optimal oxygen saturation may be determined by selecting one of the first and the second oxygen saturation or by combining the first and the second oxygen saturation. According to embodiments, a spectral transform of PPG signals may be performed to identify a frequency region associated with a pulse rate of the PPG signal. A continuous wavelet transform of the PPG signals at a scale corresponding to the identified frequency region may be performed to determine oxygen saturation from the wavelet transformed signal.
摘要翻译：根据实施例，公开了使用连续小波变换和频谱变换来确定来自光电体积描记术（PPG）信号的氧饱和度的技术。根据实施例，可以从小波变换的PPG信号确定第一氧饱和度，并且可以从光谱变换的PPG信号确定第二氧饱和度。可以通过选择第一和第二氧饱和度之一或通过组合第一和第二氧饱和度来确定最佳氧饱和度。根据实施例，可以执行PPG信号的频谱变换以识别与PPG信号的脉冲速率相关联的频率区域。可以执行以与所识别的频率区域对应的比例的PPG信号的连续小波变换，以从小波变换信号确定氧饱和度。

53. 发明授权

US08679027B2 Systems and methods for pulse processing 有权
标题翻译：用于脉冲处理的系统和方法
公开(公告)号：US08679027B2
公开(公告)日：2014-03-25
申请号：US12242828
申请日：2008-09-30
申请人： Paul Stanley Addison , James Nicholas Watson
发明人： Paul Stanley Addison , James Nicholas Watson
IPC分类号： A61B5/02
CPC分类号： A61B5/02416 , A61B5/0261 , A61B5/14551 , A61B5/6826 , A61B5/6838 , A61B5/7203 , A61B5/726
摘要： According to embodiments, techniques for using continuous wavelet transforms to process pulses from a photoplethysmographic (PPG) signal are disclosed. The continuous wavelet transform of the PPG signal may be used to identify and characterize features and their periodicities within a signal. Regions, phases and amplitudes within the scalogram associated with these features may then be analyzed to identify, locate, and characterize a true pulse within the PPG signal. Having characterized and located the pulse in the PPG (possibly also using information gained from conventional pulse processing techniques such as, for example, by identifying turning points for candidate pulse maxima and minima on the PPG, frequency peak picking for candidate scales of pulses, etc.), the PPG may be parameterized for ease of future processing.
摘要翻译：根据实施例，公开了使用连续小波变换来处理来自光电体积描记术（PPG）信号的脉冲的技术。 PPG信号的连续小波变换可用于识别和表征特征及其在信号内的周期性。然后可以分析与这些特征相关联的标尺内的区域，相位和振幅，以识别，定位和表征PPG信号内的真实脉冲。已经将脉冲特征化并定位在PPG中（可能还使用从常规脉冲处理技术获得的信息，例如通过识别候选脉冲最大值的转折点和PPG上的最小值，用于候选脉冲等级的频率峰值拾取。），可以对PPG进行参数化，以便将来处理。

54. 发明申请

US20140066785A1 SYSTEM AND METHOD FOR DETERMINING STROKE VOLUME OF AN INDIVIDUAL 有权
标题翻译：用于确定个体冲击体积的系统和方法
公开(公告)号：US20140066785A1
公开(公告)日：2014-03-06
申请号：US13605626
申请日：2012-09-06
申请人： James Nicholas Watson , Paul Stanley Addison
发明人： James Nicholas Watson , Paul Stanley Addison
IPC分类号： A61B5/0265
CPC分类号： A61B5/0265 , A61B5/0285 , A61B5/029 , A61B5/0295
摘要： A system for determining stroke volume of an individual. The system includes a skew-determining module that is configured to calculate a first derivative of photoplethysmogram (PPG) signals of the individual. The first derivative forms a derivative waveform. The skew-determining module is configured to determine a skew metric of the first derivative, wherein the skew metric is indicative of a morphology of at least one pulse wave detected from blood flow of the individual in the derivative waveform. The system also includes an analysis module that is configured to determine a stroke volume of the individual. The stroke volume is a function of the skew metric of the first derivative.
摘要翻译：一种用于确定个体的搏动量的系统。该系统包括偏差确定模块，其被配置为计算个体的光谱体积描记图（PPG）信号的一阶导数。一阶导数形成导数波形。偏移确定模块被配置为确定一阶导数的偏斜量度，其中偏斜度量指示从导数波形中的个体的血流检测到的至少一个脉搏波的形态。该系统还包括分析模块，该分析模块被配置为确定个人的冲程体积。行程体积是一阶导数的偏差度量的函数。

55. 发明授权

US08410951B2 Detecting a signal quality decrease in a measurement system 有权
标题翻译：检测测量系统中的信号质量下降
公开(公告)号：US08410951B2
公开(公告)日：2013-04-02
申请号：US12242204
申请日：2008-09-30
申请人： James Nicholas Watson , Paul Stanley Addison
发明人： James Nicholas Watson , Paul Stanley Addison
IPC分类号： G08B21/00
CPC分类号： G08B21/18 , A61B5/14551 , A61B5/6843 , A61B5/7221 , A61B5/726
摘要： Techniques for detecting a signal quality decrease are disclosed. A sensor or probe may be used to obtain a plethysmograph or photoplethysmograph (PPG) signal from a subject. A wavelet transform of the signal may be performed and a scalogram may be generated based at least in part on the wavelet transform. One or more characteristics of the scalogram may be determined. The determined characteristics may include, for example, energy values and energy structural characteristics in a pulse band, a mains hum band, and/or a noise band. Such characteristics may be analyzed to produce signal quality values and associated signal quality trends. One or more signal quality values and signal quality trends may be used to determine if a signal quality decrease has occurred or is likely to occur.
摘要翻译：公开了用于检测信号质量下降的技术。可以使用传感器或探针来获得来自受试者的体积描记器或光电体积描记器（PPG）信号。可以执行信号的小波变换，并且可以至少部分地基于小波变换来生成缩放图。可以确定缩放图的一个或多个特征。确定的特性可以包括例如脉冲频带，主干频带和/或噪声频带中的能量值和能量结构特征。可以分析这些特征以产生信号质量值和相关的信号质量趋势。可以使用一个或多个信号质量值和信号质量趋势来确定信号质量下降是否发生或可能发生。

56. 发明申请

US20130046184A1 METHOD OF ANALYZING AND PROCESSING SIGNALS 有权
公开(公告)号：US20130046184A1
公开(公告)日：2013-02-21
申请号：US13590100
申请日：2012-08-20
申请人： Paul Stanley Addison , James Nicholas Watson
发明人： Paul Stanley Addison , James Nicholas Watson
IPC分类号： A61B6/00 , A61B5/08
CPC分类号： A61B5/726 , A61B5/0002 , A61B5/0082 , A61B5/02416 , A61B5/02438 , A61B5/0816 , A61B5/14551 , A61B5/14552 , A61B5/4818 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/6896 , A61B5/7207 , A61B5/7214 , A61B5/7278 , A61B5/7282 , A61B5/742 , A61B2503/06 , G01N21/3151 , G06F19/00
摘要： A physiological measurement system is disclosed which can take a pulse oximetry signal such as a photoplethysmogram from a patient and then analyse the signal to measure physiological parameters including respiration, pulse, oxygen saturation and movement. The system comprises a pulse oximeter which includes a light emitting device and a photodetector attachable to a subject to obtain a pulse oximetry signal; analogue to digital converter means arranged to convert said pulse oximetry signal into a digital pulse oximetry signal; signal processing means suitable to receive said digital pulse oximetry signal and arranged to decompose that signal by wavelet transform means; feature extraction means arranged to derive physiological information from the decomposed signal; an analyser component arranged to collect information from the feature extraction means; and data output means arranged in communication with the analyser component.

57. 发明申请

US20130046157A1 METHOD OF ANALYZING AND PROCESSING SIGNALS 审中-公开
标题翻译：分析和处理信号的方法
公开(公告)号：US20130046157A1
公开(公告)日：2013-02-21
申请号：US13590112
申请日：2012-08-20
申请人： Paul Stanley Addison , James Nicholas Watson
发明人： Paul Stanley Addison , James Nicholas Watson
IPC分类号： A61B5/08 , A61B5/024 , A61B5/1455 , A61B6/00
CPC分类号： A61B5/726 , A61B5/0002 , A61B5/0082 , A61B5/02416 , A61B5/02438 , A61B5/0816 , A61B5/14551 , A61B5/14552 , A61B5/4818 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/6896 , A61B5/7207 , A61B5/7214 , A61B5/7278 , A61B5/7282 , A61B5/742 , A61B2503/06 , G01N21/3151
摘要： A physiological measurement system is disclosed which can take a pulse oximetry signal such as a photoplethysmogram from a patient and then analyse the signal to measure physiological parameters including respiration, pulse, oxygen saturation and movement. The system comprises a pulse oximeter which includes a light emitting device and a photodetector attachable to a subject to obtain a pulse oximetry signal; analogue to digital converter means arranged to convert said pulse oximetry signal into a digital pulse oximetry signal; signal processing means suitable to receive said digital pulse oximetry signal and arranged to decompose that signal by wavelet transform means; feature extraction means arranged to derive physiological information from the decomposed signal; an analyser component arranged to collect information from the feature extraction means; and data output means arranged in communication with the analyser component.
摘要翻译：公开了一种生理测量系统，其可以从患者获取诸如光谱体积图的脉搏血氧测定信号，然后分析该信号以测量生理参数，包括呼吸，脉搏，氧饱和度和运动。该系统包括脉搏血氧计，其包括发光装置和可附接到对象的光电检测器，以获得脉搏血氧饱和度信号; 模拟数字转换器装置，被布置成将所述脉搏血氧测定信号转换成数字脉搏血氧饱和度信号; 信号处理装置，适于接收所述数字脉搏血氧饱和度信号，并被布置成通过小波变换装置分解该信号; 特征提取装置，被布置成从分解信号中导出生理信息; 分析器组件，被布置成从特征提取装置收集信息; 以及数据输出装置，被布置成与分析器组件通信。

58. 发明授权

US08370080B2 Methods and systems for determining whether to trigger an alarm 有权
标题翻译：用于确定是否触发报警的方法和系统
公开(公告)号：US08370080B2
公开(公告)日：2013-02-05
申请号：US12249632
申请日：2008-10-10
申请人： James Nicholas Watson , Paul Stanley Addison
发明人： James Nicholas Watson , Paul Stanley Addison
IPC分类号： G01N33/49 , G06F15/00 , G11C17/00
CPC分类号： G08B21/02 , A61B5/14551 , A61B5/726 , A61B5/746
摘要： According to embodiment, systems and methods for processing a physiological measurement and generating alarms based on the measurement are provided. Multiple features of a single physiological measurement may be concurrently monitored to generate alarms. One or more of the features may be based on a trend of the physiological measurement. One or more of the features may be based on a wavelet transform of the physiological measurement. Different features may be used in different combinations to lower the percentage of false alarms while still recognizing valid alarm events.
摘要翻译：根据实施例，提供了用于处理生理测量并基于测量产生报警的系统和方法。可以同时监视单个生理测量的多个特征以产生报警。一个或多个特征可以基于生理测量的趋势。一个或多个特征可以基于生理测量的小波变换。可以以不同的组合使用不同的特征来降低误报率的百分比，同时仍然识别有效的报警事件。

59. 发明授权

US08358213B2 Systems and methods for evaluating a physiological condition using a wavelet transform and identifying a band within a generated scalogram 有权
标题翻译：用于使用小波变换来评估生理状态并识别生成的标尺内的带的系统和方法
公开(公告)号：US08358213B2
公开(公告)日：2013-01-22
申请号：US12497824
申请日：2009-07-06
申请人： James Nicholas Watson , Paul Stanley Addison , Edward M. McKenna , James P. Ochs
发明人： James Nicholas Watson , Paul Stanley Addison , Edward M. McKenna , James P. Ochs
IPC分类号： G08B21/00
CPC分类号： G06F19/00 , A61B5/14551 , A61B5/7207 , A61B5/726 , G06F19/3418 , G06K9/00516
摘要： A method and system are provided for evaluating in patient monitoring whether a signal is sensed optimally by receiving a signal, transforming the signal using a wavelet transform, generating a scalogram based at least in part on the transformed signal, identifying a pulse band in the scalogram, identifying a characteristic of the pulse band, determining, based on the characteristic of the pulse band, whether the signal is sensed optimally; and triggering an event. The characteristics of the pulse band and scalogram may be used to provide an indication of monitoring conditions.
摘要翻译：提供了一种方法和系统，用于评估在患者监视中是否通过接收信号来最佳地感测信号，使用小波变换变换信号，至少部分地基于经变换的信号产生缩放图，识别标尺中的脉冲带识别所述脉冲频带的特性，基于所述脉冲频带的特性确定所述信号是否被最佳地感测到; 并触发事件。可以使用脉冲带和标尺的特征来提供监测条件的指示。

60. 发明申请

US20120283536A1 Signal Procesing Systems and Methods Using Basis Functions and Wavelet Transforms 审中-公开
标题翻译：使用基函数和小波变换的信号处理系统和方法
公开(公告)号：US20120283536A1
公开(公告)日：2012-11-08
申请号：US13547007
申请日：2012-07-11
申请人： James Nicholas Watson , Paul Stanley Addison
发明人： James Nicholas Watson , Paul Stanley Addison
IPC分类号： A61B5/1455 , A61B5/0205
CPC分类号： A61B5/00 , A61B5/14551 , A61B5/7203 , A61B5/726 , G06K9/00516
摘要： According to embodiments, systems and methods are provided that use continuous wavelet transforms and basis functions to provide an optimized system for the determination of physiological information. In an embodiment, the basis functions may be used to refine an area of interest in the signal in frequency or in time, and the continuous wavelet transform may be used to identify a maxima ridge in the scalogram at scales with characteristic frequencies proximal to the frequency or frequencies of interest. In another embodiment, a wavelet transform may be used to identify regions of a signal with the morphology of interest while basis functions may be used to focus on these regions to determine or filter information of interest. In yet another embodiment, basis functions and continuous wavelet transforms may be used concurrently and their results combined to form optimized information or a confidence metric for determined physiological information.
摘要翻译：根据实施例，提供了使用连续小波变换和基函数来提供用于确定生理信息的优化系统的系统和方法。在一个实施例中，基函数可以用于在频率或时间上细化信号中的感兴趣区域，并且连续小波变换可以用于在具有接近频率的特征频率的标度上识别标尺中的最大值脊或兴趣频率。在另一个实施例中，可以使用小波变换来识别具有感兴趣形态的信号的区域，而基函数可用于集中在这些区域上以确定或滤除感兴趣的信息。在又一个实施例中，可以同时使用基函数和连续小波变换，并将其结果组合以形成用于确定的生理信息的优化信息或置信度量。

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