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51. 发明专利

SG172846A1 INGESTION-RELATED BIOFEEDBACK AND PERSONALIZED MEDICAL THERAPY METHOD AND SYSTEM 未知
公开(公告)号：SG172846A1
公开(公告)日：2011-08-29
申请号：SG2011048899
申请日：2010-01-06
申请人： PROTEUS BIOMEDICAL INC
发明人： JENSEN MARC , LEICHNER ROBERT , BEAULIEU PATRICK , AU-YEUNG KIT YEE , ARNE LAWRENCE , ZDEBLICK MARK , THOMPSON ANDREW , SAVAGE GEORGE , ROBERTSON TIMOTHY , BEHZADI YASHAR
IPC分类号： A61B5/375
摘要： Methods, devices and systems for acquiring information useful to support a patient in implementing and adhering to a medically prescribed therapy plan are provided. The therapy may incorporate biofeedback methods and/or personalized therapy aspects. A method includes steps of receiving, by a receiving device, biometric information associated with an ingestible event marker; analyzing, by a computing device having a microprocessor configured to perform a biometric information analysis, the biometric information; and determining a therapeutic recommendation at least partly on the basis of the analysis and/or integrating biofeedback techniques into patient therapy or activity. A system includes a biometric information module to receive biometric information associated with an ingestible event marker; an analysis module to analyze the biometric information; and a determination module to optionally determine and communicate a therapeutic recommendation at least partly on the basis of the analysis.

52. 发明专利

CA2676280A1 IN-BODY POWER SOURCE HAVING HIGH SURFACE AREA ELECTRODE 未知
公开(公告)号：CA2676280A1
公开(公告)日：2008-08-21
申请号：CA2676280
申请日：2008-02-14
申请人： PROTEUS BIOMEDICAL INC
发明人： COZAD BRAD , SNYDER ERIC , HAFEZI HOOMAN , ROBERTSON TIMOTHY
IPC分类号： H01M8/00
摘要： Power sources that enable in-body devices, such as implantable and ingest ible devices, are provided. Aspects of the in-body power sources of the inve ntion include a solid support, a first high surface area electrode and a sec ond electrode. Embodiments of the in-power sources are configured to emit a detectable signal upon contact with a target physiological site. Also provid ed are methods of making and using the power sources of the invention.

53. 发明专利

BR112012013504A2 sistema marcador de evento ingerível integrado com produto farmacêutico 未知
公开(公告)号：BR112012013504A2
公开(公告)日：2016-06-07
申请号：BR112012013504
申请日：2010-12-02
申请人： PROTEUS BIOMEDICAL INC
发明人： COSTELLO BENEDICT , HAFEZI HOOMAN , DUCK ROBERT , ROBERTSON TIMOTHY
IPC分类号： A61J3/06 , A61J3/10 , A61K9/20 , A61K9/48
摘要： sistema marcador de evento ingerível integrado com produto farmacêutico. um sistema e método são fornecidos para fixar um dispositivo eletrônico ingerível a um produto farmacêutico sem danificar o dispositivo eletrônico ingerível. o produto inclui o dispositivo eletrônico ingerível sendo colocado no produto de acordo com um aspecto da presente invenção. de acordo com outro aspecto da presente invenção, o dispositivo eletrônico ingerível é colocado dentro do produto. várias modalidades são divulgadas de acordo com a presente invenção para proteção e/ou revestimento do marcador eletrônico, bem como fixação do dispositivo eletrônico ingerível no produto.

54. 发明专利

AU2011237612A1 Miniature ingestible device 未知
公开(公告)号：AU2011237612A1
公开(公告)日：2012-11-01
申请号：AU2011237612
申请日：2011-04-07
申请人： PROTEUS BIOMEDICAL INC
发明人： ROBERTSON TIMOTHY , HAFEZI HOOMAN , SCHMIDT RAYMOND
IPC分类号： A61J3/07 , A61J3/06 , A61K9/28 , A61K9/48 , A61K47/00
摘要： The present invention discloses multiple approaches to preventing the capsule walls and other material from interfering with the performance of an electronic device once the device is activated by surrounding fluid. In accordance with the teachings of the present invention, a miniature ingestible device (MID) may be created using excipients and films. The MID, in accordance with various aspects of the present invention, will have a coating or laminating surrounding an electronic device and separating and isolating the device from the pharmaceutical product or drug within the capsule once the capsule is ingested as well as from the capsule itself as the capsule walls begin to collapse during the disintegration process.

55. 发明专利

SG175388A1 HIGHLY RELIABLE INGESTIBLE EVENT MARKERS AND METHODS FOR USING THE SAME 未知
公开(公告)号：SG175388A1
公开(公告)日：2011-12-29
申请号：SG2011079332
申请日：2010-04-27
申请人： PROTEUS BIOMEDICAL INC
发明人： HAFEZI HOOMAN , AU-YEUNG KIT YEE , DUCK ROBERT , HOLEN MARIA , ROBERTSON TIMOTHY , COSTELLO BENEDICT
摘要： Ingestible event markers having high reliability are provided. Aspects of the ingestible event markers include a support, a control circuit, a first electrochemical material, a second electrochemical material and a membrane. In addition, the ingestible event markers may include one or more components that impart high reliability to the ingestible event marker. Further, the ingestible event markers may include an active agent. In some aspects, the active agent, such as a pharmaceutically active agent or a diagnostic agent may be associated with the membrane.

56. 发明专利

SG172845A1 HIGH-THROUGHPUT PRODUCTION OF INGESTIBLE EVENT MARKERS 未知
公开(公告)号：SG172845A1
公开(公告)日：2011-08-29
申请号：SG2011048881
申请日：2010-01-05
申请人： PROTEUS BIOMEDICAL INC
发明人： HAFEZI HOOMAN , ZDEBLICK MARK , AU-YEUNG KITYEE , MOON GREGORY , DUCK ROBERT , HOLEN MARIA , ROBERTSON TIMOTHY , SNYDER ERIC , FOLENA MAURO , COSTELLO BENEDICT , RAO PRATISH
摘要： High-throughput ingestible event marker manufacturing systems are provided. The systems include an assembly unit configured to stably associate an ingestible event marker with a carrier to produce a product. Also provided are manufacturing methods to produce such products which include assembling an ingestible event marker with an assembly unit configured to stably associate an ingestible event marker with a carrier.

57. 发明专利

CA2782683A1 INTEGRATED INGESTIBLE EVENT MARKER SYSTEM WITH PHARMACEUTICAL PRODUCT 未知
公开(公告)号：CA2782683A1
公开(公告)日：2011-06-09
申请号：CA2782683
申请日：2010-12-02
申请人： PROTEUS BIOMEDICAL INC
发明人： HAFEZI HOOMAN , DUCK ROBERT , ROBERTSON TIMOTHY , COSTELLO BENEDICT
IPC分类号： A61J3/06 , A61J3/10 , A61K9/20 , A61K9/48
摘要： A system and method are provided for securing an ingestible electronic device to a pharmaceutical product without damaging the ingestible electronic device. The product includes the ingestible electronic device being placed on the product in accordance with one aspect of the present invention. In accordance with another aspect of the present invention, the ingestible electronic device is placed inside the product. Various embodiments are disclosed in accordance with the present invention for protecting and/or coating of the electronic marker as well as securing the ingestible electronic device onto the product.

58. 发明专利

AU2008216170A1 In-body power source having high surface area electrode 未知
公开(公告)号：AU2008216170A1
公开(公告)日：2008-08-21
申请号：AU2008216170
申请日：2008-02-14
申请人： PROTEUS BIOMEDICAL INC
发明人： SNYDER ERIC , ROBERTSON TIMOTHY , COZAD BRAD , HAFEZI HOOMAN
IPC分类号： H01M8/00
摘要： Power sources that enable in-body devices, such as implantable and ingestible devices, are provided. Aspects of the in-body power sources of the invention include a solid support, a first high surface area electrode and a second electrode. Embodiments of the in-power sources are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the power sources of the invention.

59. 发明专利

AU2006239221A1 Pharma-informatics system 未知
公开(公告)号：AU2006239221A1
公开(公告)日：2006-11-02
申请号：AU2006239221
申请日：2006-04-28
申请人： PROTEUS BIOMEDICAL INC
发明人： PIKELNY ALEKSANDR , ROBERTSON TIMOTHY , THOMPSON ANDREW , ZDEBLICK MARK
IPC分类号： G06F19/00
摘要： A system comprising: an active agent; a pharmaceutically acceptable carrier; a signal generation component for emitting a current, the signal generation component comprising: a circuitry layer on a silicon support layer; an anode layer comprising a metal material electrically coupled to the circuitry layer; and a cathode layer comprising a salt material electrically coupled to the circuitry layer and electrically isolated from the anode layer; wherein the anode layer and the cathode layer are made from different materials selected to provide a voltage potential difference as a result of the materials being in contact with a conducting liquid to power the signal generation component, wherein the circuitry layer and the silicon support layer are positioned between the anode and cathode layers; wherein the circuitry layer is configured to produce in the conducting liquid a current between the anode layer and the cathode layer; an activation component configured to activate the signal generation component to generate the current through the conducting liquid; and a receiver configured to remotely detect the emitted current.

60. 发明公开

EP1968693A4 IMPLANTABLE INTEGRATED CIRCUIT 审中-公开
标题翻译：植入集成电路
公开(公告)号：EP1968693A4
公开(公告)日：2011-04-27
申请号：EP06847996
申请日：2006-12-22
申请人： PROTEUS BIOMEDICAL INC
发明人： ZDEBLICK MARK , LEICHNER ROBERT , ARIA BEHARD , JANI NILAY , LI HAIFENG , THOMPSON TODD , ARNE LAWRENCE , ROBERTSON TIMOTHY , BI YAFEI , GELFANDBEIN VLADIMIER
IPC分类号： A61B5/04
CPC分类号： A61N1/056 , A61B5/0422 , A61N1/025 , A61N1/362 , A61N1/3686 , A61N1/372 , A61N1/37205 , A61N1/37276 , A61N1/37288 , A61N1/3756

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