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51. 发明授权

US5985636A Method and compositions for inhibiting oxidation 失效
标题翻译：抑制氧化的方法和组合物
公开(公告)号：US5985636A
公开(公告)日：1999-11-16
申请号：US799788
申请日：1997-02-12
申请人： James Ian Gray , Alden M. Booren , Muraleedharan G. Nair , Gale M. Strasburg , Haibo Wang , Enayat A. Gomaa , Yu-Chen Chang
发明人： James Ian Gray , Alden M. Booren , Muraleedharan G. Nair , Gale M. Strasburg , Haibo Wang , Enayat A. Gomaa , Yu-Chen Chang
IPC分类号： A23L3/3472 , A23L3/3481 , C12N9/14
CPC分类号： A23L3/3472 , A23L3/3481
摘要： Anthocyanin containing fractions isolated from tart cherries and exhibiting inhibition of oxidation when introduced into various materials is described. The fractions are particularly useful in high and low moisture foods.
摘要翻译：描述了从挞樱桃分离的含花青素的级分，并且当引入各种材料时表现出抑制氧化。这些级分在高低湿度食品中特别有用。

52. 发明授权

US5658794A Method for controlling fungal disease in turfgrasses using Pseudomonas aureofaciens ATCC 55670 失效
标题翻译：使用金黄色葡萄球菌ATCC55670控制草坪草中真菌病的方法
公开(公告)号：US5658794A
公开(公告)日：1997-08-19
申请号：US568781
申请日：1995-12-07
申请人： Muraleedharan G. Nair , Joseph M. Vargas , Jon F. Powell , Amitabh Chandra , Alvin Ronald Detweiler
发明人： Muraleedharan G. Nair , Joseph M. Vargas , Jon F. Powell , Amitabh Chandra , Alvin Ronald Detweiler
IPC分类号： A01N63/00 , C12N1/12 , C12N1/20
CPC分类号： C12R1/38 , A01N63/00 , Y10S435/822 , Y10S435/874
摘要： A method for controlling fungal diseases in turfgrasses using a Pseudomonas aureofaciens. The Pseudomonas aureofaciens is particularly useful in inhibiting dollar spot (Sclerotinia homoeocarpa) in turfgrasses. The method is environmentally safe and economical.
摘要翻译：一种使用金黄色葡萄球菌（Strepomonas aureofaciens）控制草坪草中真菌病的方法。金黄色假单胞菌特别适用于抑制草坪草中的美元斑点（Sclerotinia homoeocarpa）。该方法环保，经济。

53. 发明授权

US5310754A Method for controlling insects 失效
标题翻译：防治昆虫的方法
公开(公告)号：US5310754A
公开(公告)日：1994-05-10
申请号：US5154
申请日：1993-01-15
申请人： Muraleedharan G. Nair
发明人： Muraleedharan G. Nair
IPC分类号： A01N43/16 , A01N49/00 , C07D309/38 , C07D313/00 , C12P17/08
CPC分类号： C12R1/545 , A01N43/16 , A01N49/00 , C07D309/38 , C07D313/00 , C12P17/08
摘要： A method for controlling insects using nitrophenyl pyrones is described. The pyrones are preferably derived from Streptomyces sp. by a method involving growth and extraction of the pyrones. A novel pyrone, griseulin is also described.
摘要翻译：描述了使用硝基苯基吡喃酮控制昆虫的方法。这些小蠊优选衍生自链霉菌属（Streptomyces sp。）。通过涉及生长和提取pyrones的方法。还描述了一种新的吡喃酮，灰泥蛋白酶。

54. 发明授权

US5279949A Process for the isolation and purification of taxol and taxanes from Taxus spp 失效
标题翻译：从紫杉属分离纯化紫杉醇和紫杉烷的方法
公开(公告)号：US5279949A
公开(公告)日：1994-01-18
申请号：US986368
申请日：1992-12-07
申请人： Muraleedharan G. Nair
发明人： Muraleedharan G. Nair
IPC分类号： C07D305/14 , C12P15/00 , C12P17/02 , C07D305/00 , C12N5/00 , C12N5/02
CPC分类号： C12P15/00 , C07D305/14 , C12P17/02
摘要： A process for the separation of taxanes, particularly taxol, from ornamental yew tissue is described. The process involves a specific solvent mixture of ethanol and water which is between 50 to 80 percent by volume ethanol and decolorizing of the resulting extract using activated carbon containing the crude taxanes. The taxanes are separated from the crude extract by a normal phase chromatographic step which preferably is through vacuum or medium pressure column chromatographic separation, using inexpensive silica gel as an absorbent.
摘要翻译：描述了从观赏紫杉组织分离紫杉烷类，特别是紫杉醇的方法。该方法包括乙醇和水的特定溶剂混合物，其为50至80体积％乙醇，并且使用含有粗紫杉烷的活性炭对所得提取物进行脱色。通过正相色谱步骤将紫杉烷与粗提取物分离，其优选通过真空或中压柱色谱分离，使用廉价的硅胶作为吸收剂。

55. 发明授权

US5236949A Method for controlling insects 失效
标题翻译：防治昆虫的方法
公开(公告)号：US5236949A
公开(公告)日：1993-08-17
申请号：US11512
申请日：1993-02-01
申请人： Muraleedharan G. Nair
发明人： Muraleedharan G. Nair
IPC分类号： A01N43/16 , A01N49/00 , C07D309/38 , C07D313/00 , C12P17/08
CPC分类号： C12R1/545 , A01N43/16 , A01N49/00 , C07D309/38 , C07D313/00 , C12P17/08
摘要： A method for controlling insects using nitrophenyl pyrones is described. The pyrones are preferably derived from Streptomyces sp. by a method involving growth and extraction of the pyrones. A novel pyrone, griseulin is also described.
摘要翻译：描述了使用硝基苯基吡喃酮控制昆虫的方法。这些小蠊优选衍生自链霉菌属（Streptomyces sp。）。通过涉及生长和提取pyrones的方法。还描述了一种新的吡喃酮，灰泥蛋白酶。

56. 发明授权

US5085682A Method and compositions for stimulating vesticular-arbuscular mycorrhizal fungi using isoflavonoids 失效
标题翻译：使用异黄酮刺激月球 - 丛枝菌根真菌的方法和组合物
公开(公告)号：US5085682A
公开(公告)日：1992-02-04
申请号：US591420
申请日：1990-10-01
申请人： Gene R. Safir , Muraleedharan G. Nair , Jose O. Siqueira
发明人： Gene R. Safir , Muraleedharan G. Nair , Jose O. Siqueira
IPC分类号： A01G1/04 , A01C1/06 , A01G7/00 , A01N33/06 , A01N43/16 , A01N43/40 , A01N43/50 , A01N57/00 , A01N63/04 , C05F11/08 , C07D311/22 , C12N1/14 , C12R1/645
CPC分类号： A01N43/16 , A01N63/04
摘要： A method and compositions for stimulating the growth of vesicular-arbuscular mycorrhizal fungi alone or in the presence of a plant material using isoflavonoid compounds is described. The isoflavonoids are preferably of the formula: ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are selected from the group consisting of hydrogen, hydroxyl and alkoxy, particularly methoxy.
摘要翻译：描述了使用异黄酮化合物单独或在植物材料存在下刺激水泡 - 丛枝菌根真菌生长的方法和组合物。异黄酮优选具有下式：其中R 1，R 2和R 3选自氢，羟基和烷氧基，特别是甲氧基。

57. 发明授权

US5066585A Method of inhibiting fungus using novel antifungal compounds 失效
标题翻译：使用新型抗真菌化合物抑制真菌的方法
公开(公告)号：US5066585A
公开(公告)日：1991-11-19
申请号：US617219
申请日：1990-11-23
申请人： Alan R. Putnam , Saroj K. Mishra , Muraleedharan G. Nair
发明人： Alan R. Putnam , Saroj K. Mishra , Muraleedharan G. Nair
IPC分类号： C12P19/56
CPC分类号： C12R1/29 , C12P19/56
摘要： A new species of Micromonospora, in particular Micromonospora spartanea ATCC 53803, is described. The species produces antifungal compounds spartanamicins A and B. Methods for the production, isolation and characterization of the compounds are described. The compounds contain deoxy-L-fucose, as well as another hexose and an amino sugar.
摘要翻译：描述了一种新的小单孢菌，特别是小孢子虫（Micomonospora spartanea）ATCC 53803。该物种产生抗真菌化合物spartanamicin A和B.描述了化合物的生产，分离和表征的方法。该化合物含有脱氧-L-岩藻糖，以及另一种己糖和氨基糖。

58. 发明授权

US4876277A Antimicrobial/antifungal compositions 失效
标题翻译：抗微生物/抗真菌组合物
公开(公告)号：US4876277A
公开(公告)日：1989-10-24
申请号：US55737
申请日：1987-05-29
申请人： Basil A. Burke , Muraleedharan G. Nair
发明人： Basil A. Burke , Muraleedharan G. Nair
IPC分类号： A01N43/30 , C07D317/64
CPC分类号： A01N43/30 , C07D317/64
摘要： Substituted olefinic (allyl) benzene compounds which exhibit important antimicrobial (antibacterial and antifungal) activity, compositions and methods of delivery against pathovars and pathogens, and methods of synthesis from commonly available reactants. The antifungal composition active ingredient is one or more 4,5-substituted 2,3-alkylidenedioxy-1-olefinic benzenes of the formula: ##STR1## where R.sub.1 and R.sub.2 may be the same or different, and are selected from OH, and C.sub.1 -C.sub.5 alkoxy (--OR) or thioalkyl (--SR) groups. R.sub.3 and R.sub.4 are selected from H and C.sub.1 -C.sub.5 alkyl, alkenyl and alkynyl groups, and R.sub.5 is selected from C.sub.3 -C.sub.7 alkyl, alkenyl and alkynyl groups. The preferred compounds are 4,5-substituted-2,3-methylenedioxy-1-allyl benzenes. Where R.sub.1 =OCH.sub.3, R.sub.2 =OH, R.sub.3 and R.sub.4 =H and R.sub.5 =allyl (2',3' propenyl) the compound may be called nor methyl-pseudo-dillapiole. Where R.sub.1 =R.sub.2 =OCH.sub.3, R.sub.3 and R.sub.4 are again H, and R.sub.5 =allyl, the compound may be called pseudo-dillapiole. Compositions including these compounds exhibit antimicrobial activity against a variety of pathogens and pathovars, e.g., Xanthomonas campestris spp. bacteria, antifungal activity against a variety of fungi and bacteria, and are highly specific, e.g., antifungal activity against wheat powdery mildew, but do not affect seed germination or have herbicidal or insecticial activity. Methods and compositions for delivery of these agents against such pathogens, and methods of chemical synthesis of the compounds are disclosed.
摘要翻译：显示出重要的抗微生物（抗菌和抗真菌）活性，组合物和递送针对病原体和病原体的方法的取代的烯丙基（烯丙基）苯化合物，以及通常可得的反应物的合成方法。抗真菌组合物活性成分是一种或多种下式的4,5-取代的2,3-亚烷基二氧基-1-烯烃苯：其中R 1和R 2可以相同或不同，并且选自OH，和C 1 -C 5烷氧基（-OR）或硫代烷基（-SR）基团。 R3和R4选自H和C1-C5烷基，烯基和炔基，R5选自C3-C7烷基，烯基和炔基。优选的化合物是4,5-取代-2,3-亚甲二氧基-1-烯丙基苯。其中R1 = OCH3，R2 = OH，R3和R4 = H，R5 =烯丙基（2'，3'丙烯基），化合物可称为甲基假鞭毛虫。当R 1 = R 2 = OCH 3时，R 3和R 4再次为H，R 5为烯丙基，该化合物可称为伪鞭毛虫。包括这些化合物的组合物对各种病原体和病原体表现出抗菌活性，例如野油菜黄单胞菌（Xanthomonas campestris spp。）细菌，针对各种真菌和细菌的抗真菌活性，并且是高度特异性的，例如抗小麦白粉病的抗真菌活性，但不影响种子发芽或具有除草或昆虫活性。公开了用于递送这些试剂以抵抗这种病原体的方法和组合物，以及化合物的化学合成方法。

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