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51. 发明授权

US5184109A Overcharge preventive device for automotive batteries 失效
标题翻译：汽车电池过充电装置
公开(公告)号：US5184109A
公开(公告)日：1993-02-02
申请号：US641413
申请日：1991-01-15
申请人： Hirokazu Tanaka , Koichi Ito
发明人： Hirokazu Tanaka , Koichi Ito
IPC分类号： B60R16/02 , B60R16/03 , H02J7/00 , H02J7/14
CPC分类号： H02J7/1461 , H02J7/009 , B60R16/03
摘要： An overcharge preventive device for an automotive battery charging circuit comprises an odorant sensor 6 for detecting the amount of gas generated from the battery 1 during charging (FIG. 3). A detector circuit 7 generates an overcharge detection signal when the amount of gas exceeds a predetermined level. In response thereto, the display or monitor lamp 8 displays the overcharged state, and the interruptor circuit 9 separates the alternator 5 from the battery 1. Alternatively, when the automobile has an audio device such as radio, a voltage detector 19 detects the voltage across the load 4 and outputs a signal when the voltage exceeds a predetermined level, an alarm signal generator 20 generating an audio signal in response to the output signal of the voltage detector 19, such that an alarm sound or voice is produced by a loudspeaker 17 via the amplifier 16 (FIG. 4).
摘要翻译：用于汽车电池充电电路的过充电防止装置包括用于在充电期间检测从电池1产生的气体量的气味传感器6（图3）。当气体量超过预定水平时，检测器电路7产生过充电检测信号。响应于此，显示器或监视灯8显示过充电状态，并且断路器电路9将交流发电机5与电池1分离。或者，当汽车具有诸如无线电的音频设备时，电压检测器19检测电压负载4并且当电压超过预定电平时输出信号，报警信号发生器20响应于电压检测器19的输出信号产生音频信号，使得扬声器17通过扬声器17产生警报声音放大器16（图4）。

52. 发明授权

US5110811A Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same 失效
标题翻译：三肽化合物，其生产方法和含有它们的药物组合物
公开(公告)号：US5110811A
公开(公告)日：1992-05-05
申请号：US491205
申请日：1990-03-09
申请人： Masakuni Okuhara , Hirokazu Tanaka , Toshio Goto , Tohru Kino , Hiroshi Hatanaka
发明人： Masakuni Okuhara , Hirokazu Tanaka , Toshio Goto , Tohru Kino , Hiroshi Hatanaka
IPC分类号： A01N43/38 , A61K31/00 , A61K31/33 , A61K31/40 , A61K31/407 , A61K31/435 , A61K31/4353 , A61K31/436 , A61K31/445 , A61K31/4465 , A61K31/4523 , A61K31/453 , A61K31/4745 , A61P31/00 , A61P31/04 , A61P37/00 , A61P37/06 , C07D491/14 , C07D498/04 , C07D498/14 , C07D498/18 , C07D519/00 , C07H19/01 , C12N1/20 , C12P17/16 , C12P17/18 , C12P19/44 , C12R1/465 , C12R1/55
CPC分类号： C07D498/18 , C07H19/01 , C12P17/188 , C12P19/44 , C12R1/465 , C12R1/55 , Y02P20/55 , Y10S435/886 , Y10S435/898
摘要： This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: ##STR1## to a process for their production, to a pharmaceutical composition containing the same and to a use thereof.

53. 发明授权

US4643990A N-acyl peptide, processes for their preparation and pharmaceutical compositions thereof 失效
标题翻译： N-酰基肽，其制备方法及其药物组合物
公开(公告)号：US4643990A
公开(公告)日：1987-02-17
申请号：US452827
申请日：1982-12-23
申请人： Kazuyoshi Umehara , Keizo Yoshida , Hirokazu Tanaka , Itsuo Uchida , Masanobu Kohsaka , Hiroshi Imanaka
发明人： Kazuyoshi Umehara , Keizo Yoshida , Hirokazu Tanaka , Itsuo Uchida , Masanobu Kohsaka , Hiroshi Imanaka
IPC分类号： A61K38/00 , C07K5/06 , C07K5/065 , C07K5/068 , C07K5/072 , A61K37/43 , C07C67/02 , C07C69/52 , C07C101/26 , C07C101/30 , C07C143/12 , C07K5/08
CPC分类号： C07K5/06104 , C07K5/06052 , C07K5/06078 , C07K5/06086 , A61K38/00
摘要： N-acylpeptides are disclosed of the formula: ##STR1## wherein R.sup.1 is alkanoyloxy or alkenoyloxy; R.sup.2 is alkyl or alkenyl; R.sup.3 and R.sup.4 are each lower alkyl, hydroxy(lower)alkyl, ar(lower)alkyl, esterified carboxy(lower)alkyl, carboxy(lower)alkyl, protected amino(lower)alkyl or amino(lower)alkyl; R.sup.5 is hydrogen, hydroxy(lower)alkyl, protected amino(lower)alkyl, amino(lower)alkyl, carboxy(lower)alkyl or esterified carboxy(lower)alkyl; R.sup.6 is carboxy, esterified carboxy or sulfo(lower)alkyl; A.sup.1, A.sup.2 and A.sup.3 are each bond or lower alkylene; and m and n are each an integer of 0 or 1; or its pharmaceutically acceptable salt. These compounds have anti-complementary activity and fibrinolytic activity, and are useful as therapeutic agents for immune-complex diseases or autoimmune diseases such as nephritis, rheumatic diseases, systemic lupus erythematosus, etc. and thrombosis such as cerebral apoplexy, coronary insufficiency, pulmonary embolism, etc.
摘要翻译： N-酰基肽公开于下式：其中R 1是烷酰氧基或烯酰基氧基; R2是烷基或烯基; R 3和R 4各自为低级烷基，羟基（低级）烷基，芳（低级）烷基，酯化羧基（低级）烷基，羧基（低级）烷基，被保护的氨基（低级）烷基或氨基（低级） R5是氢，羟基（低级）烷基，被保护的氨基（低级）烷基，氨基（低级）烷基，羧基（低级）烷基或酯化羧基（低级）烷基; R6是羧基，酯化的羧基或磺基（低级）烷基; A1，A2和A3各自为键或低级亚烷基; m和n分别为0或1的整数; 或其药学上可接受的盐。这些化合物具有抗互补活性和纤维蛋白溶解活性，并且可用作免疫复合物疾病或自身免疫性疾病如肾炎，风湿性疾病，系统性红斑狼疮等的治疗剂，以及血栓形成如脑中风，冠状动脉功能不全，肺栓塞等等

54. 发明授权

US4512980A Peptide, process for preparation thereof and use thereof 失效
标题翻译：肽，其制备方法及其用途
公开(公告)号：US4512980A
公开(公告)日：1985-04-23
申请号：US402438
申请日：1982-07-28
申请人： Yoshihiko Kitaura , Osamu Nakaguchi , Keiji Hemmi , Matsuhiko Aratani , Hidekazu Takeno , Satoshi Okada , Hirokazu Tanaka , Masashi Hashimoto
发明人： Yoshihiko Kitaura , Osamu Nakaguchi , Keiji Hemmi , Matsuhiko Aratani , Hidekazu Takeno , Satoshi Okada , Hirokazu Tanaka , Masashi Hashimoto
IPC分类号： A61K38/00 , A61P31/04 , A61P37/00 , A61P37/04 , C07C237/22 , C07K1/06 , C07K1/113 , C07K5/02 , C07K5/04 , C07K7/02 , C07K9/00 , C07C103/52 , A61K37/02
CPC分类号： C07C243/00 , C07K5/0215 , C07K9/005 , C12R1/465 , A61K38/00
摘要： The invention relates to novel peptides of pharmacological activity, of the formula ##STR1## wherein R.sup.1 is hydrogen or acyl;R.sup.2 is carboxy or protected carboxy or a group of the formula: --COHN--R.sub.a.sup.2 wherein R.sub.a.sup.2 is carboxy (lower) alkyl or protected carboxy (lower) alkyl;R.sup.3 is carboxy, protected carboxy, lower alkyl, hydroxyphenyl, carbamoyl or a group of the formula: ##STR2## wherein R.sub.a.sup.3 is hydrogen, amino, protected amino or acylamino, R.sub.b.sup.3 is carboxy or protected carboxy;R.sup.p is carboxy, protected carboxy, carbamoyl, carboxy (lower) alkyl or protected carboxy (lower) alkyl;l is an integer 0;m is an interger 3; andn is an integer 1, provided that when R.sup.1 is hydrogen or acyl,R.sup.2 is carboxy, protected carboxy or a group of the formula:--CONHR.sub.a.sup.2 wherein R.sub.a.sup.2 is carboxy (lower) alkyl or protected carboxy (lower) alkyl,R.sup.p is carboxy, or protected carboxy,R.sup.3 is carbamoyl, lower alkyl or hydroxyphenyl or a group of the formula: ##STR3## wherein R.sub.a.sup.3 is hydrogen or acylamino and R.sub.b.sup.3 is carboxy or protected carboxy, andwhen R.sup.p is carbamoyl, thenR.sup.1 is acyl.

55. 发明授权

US4504584A Cultures of novel strains of Streptomyces 失效
标题翻译：链霉菌新菌株的培养
公开(公告)号：US4504584A
公开(公告)日：1985-03-12
申请号：US379851
申请日：1982-05-19
申请人： Yoshihiko Kitaura , Osamu Nakaguchi , Keiji Hemmi , Matsuhiko Aratani , Hidekazu Takeno , Satoshi Okada , Hirokazu Tanaka , Masashi Hashimoto , Yoshio Kuroda , Eiko Iguchi , Masanobu Kohsaka , Hatsuo Aoki , Hiroshi Imanaka
发明人： Yoshihiko Kitaura , Osamu Nakaguchi , Keiji Hemmi , Matsuhiko Aratani , Hidekazu Takeno , Satoshi Okada , Hirokazu Tanaka , Masashi Hashimoto , Yoshio Kuroda , Eiko Iguchi , Masanobu Kohsaka , Hatsuo Aoki , Hiroshi Imanaka
IPC分类号： A61K38/00 , C07K5/02 , C07K5/06 , C07K5/062 , C07K5/072 , C07K9/00 , C12N1/20 , C12R1/465
CPC分类号： C07C243/00 , C07K5/0215 , C07K5/06026 , C07K5/06104 , C07K9/005 , C12R1/465 , A61K38/00 , Y10S435/886 , Y10S930/19
摘要： The invention relates to a biologically pure culture of new strains of the microorganism Streptomyces which are capable upon fermentation of producing a peptide of pharmacological activity.
摘要翻译：本发明涉及生物学纯培养的新型菌株的微生物链霉菌，其能够在发酵时产生药理活性肽。

56. 发明授权

US4466947A Denitration catalyst and denitrating method 失效
标题翻译：脱硝催化剂和脱硝方法
公开(公告)号：US4466947A
公开(公告)日：1984-08-21
申请号：US456398
申请日：1983-01-07
申请人： Makoto Imanari , Bunzi Oshida , Yusaku Arima , Hirokazu Tanaka , Yoshinori Todo , Norihisa Kobayashi , Toshikuni Sera
发明人： Makoto Imanari , Bunzi Oshida , Yusaku Arima , Hirokazu Tanaka , Yoshinori Todo , Norihisa Kobayashi , Toshikuni Sera
IPC分类号： B01D53/94 , B01J23/22 , B01J23/30 , B01J27/053 , B01J8/00 , C01B21/00
CPC分类号： B01J23/22 , B01D53/9418 , B01D2251/2062 , B01D2255/2047 , B01D2255/20707 , B01D2255/20723 , B01D2255/20776
摘要： A denitration catalyst comprising at least three metal components, (A) titanium, (B) tungsten and/or magnesium, and (C) vanadium, the titanium and tungsten being contained as oxides and the magnesium and vanadium being contained in the form of an oxide or a sulfate or both, said catalyst being composed of a porous molded article of a mixture of an oxide of component A and an oxide and/or a sulfate of component B, the atomic ratio of component B to component A being from 0.01 to 1, and a vanadium compound localized in that area of said molded article which extends from its outermost surface to a depth of 500 microns or less, the content of the vanadium compound in said area being 0.1 to 15% by weight; and a method for removing nitrogen oxides from a waste gas, which comprises contacting a waste gas containing nitrogen oxides, together with ammonia and molecular oxygen, at a temperature of 150.degree. to 650.degree. C., with the aforesaid catalyst.
摘要翻译：包含至少三种金属组分（A）钛，（B）钨和/或镁和（C）钒）的脱硝催化剂，所述钛和钨作为氧化物包含，并且所述镁和钒以氧化物或硫酸盐或两者，所述催化剂由组分A的氧化物和组分B的氧化物和/或硫酸盐的混合物的多孔模制品组成，组分B与组分A的原子比为0.01至 1和位于所述模制品的该区域的钒化合物，其从最外表面延伸至500微米或更小的深度，所述区域中的钒化合物的含量为0.1至15重量％; 以及从废气中除去氮氧化物的方法，该方法包括在150℃至650℃的温度下将含有氮氧化物的废气与氨和分子氧与上述催化剂接触。

57. 发明授权

US4414226A 1,4-Naphtoquinone derivatives and their use in treating coccidiosis 失效
标题翻译： 1,4-萘醌衍生物及其在治疗球虫病中的应用
公开(公告)号：US4414226A
公开(公告)日：1983-11-08
申请号：US317897
申请日：1981-10-30
申请人： Koichi Ikushima , Hirokazu Tanaka , Ohe Osamu , Eiko Kino , Masanobu Kohsaka , Hatsuo Aoki , Akira Arakawa , Hiroshi Imanaka
发明人： Koichi Ikushima , Hirokazu Tanaka , Ohe Osamu , Eiko Kino , Masanobu Kohsaka , Hatsuo Aoki , Akira Arakawa , Hiroshi Imanaka
IPC分类号： A61K31/12 , A61K31/16 , A61K31/165 , A61K31/19 , A61K31/215 , A61K31/22 , A61K31/35 , A61K31/352 , A61K31/365 , A61K31/66 , A61P33/02 , C07C50/10 , C07C65/03 , C07C65/105 , C07C66/00 , C07C67/00 , C07C69/02 , C07C69/94 , C07C69/95 , C07C231/00 , C07C233/12 , C07C235/46 , C07C235/84 , C07C275/54 , C07C313/00 , C07C323/22 , C07C323/61 , C07D311/78 , C07F9/38 , C07F9/40 , C12P7/40 , C12P7/66 , C12P17/06 , C12R1/465
CPC分类号： C12P17/06 , C07C323/00 , C07C66/00 , C07D311/78 , C12P7/40
摘要： 1,4-naphthoquinone derivatives represented by the following general formula: ##STR1## (wherein R.sup.1 represents a hydrogen atom, a hydroxy group, a lower alkoxy group or an arylthio group, R.sup.2 represents a carboxy group, an esterified carboxy group or an amidated carboxy group or, when taken together, R.sup.1 and R.sup.2 form a group of ##STR2## R.sup.3 represents a hydrogen atom or a lower alkyl group, R.sup.4 represents a lower alkyl group, R.sup.5 represents a hydrogen atom or a halogen atom, and R.sup.6 represents a hydrogen atom, a lower alkyl group or a lower alkanoyl group), and the salts of the carboxy group thereof, which are novel compounds having an anticoccidium activity, and which can be obtained by synthesis or, partly, by cultivation of Streptomyces auranticolor.
摘要翻译： PCT No.PCT / JP81 / 00046 Sec。 371日期1981年10月30日 102（e）日期1981年10月30日PCT提交1981年3月6日PCT公布。公开号WO81 / 02574 日期：1981年9月17日由以下通式表示的1,4-萘醌衍生物：其中R1表示氢原子，羟基，低级烷氧基或芳硫基，R2表示羧基，酯化羧基或酰胺基羧基，或者当R 1和R 2一起形成一个基团时，R 3表示氢原子或低级烷基，R 4表示低级烷基，R 5表示氢原子或卤素原子，R6表示氢原子，低级烷基或低级烷酰基）及其羧基的盐，它们是具有抗球虫活性的新型化合物，可以通过合成或部分通过培养获得的链霉菌。

58. 发明授权

US4354966A Peptides, process for preparation thereof and use thereof 失效
标题翻译：肽，其制备方法和用途
公开(公告)号：US4354966A
公开(公告)日：1982-10-19
申请号：US193453
申请日：1980-10-03
申请人： Yoshihiko Kitaura , Osamu Nakaguchi , Keiji Hemmi , Matsuhiko Aratani , Hidekazu Takeno , Satoshi Okada , Hirokazu Tanaka , Masashi Hashimoto
发明人： Yoshihiko Kitaura , Osamu Nakaguchi , Keiji Hemmi , Matsuhiko Aratani , Hidekazu Takeno , Satoshi Okada , Hirokazu Tanaka , Masashi Hashimoto
IPC分类号： A61K38/00 , C07K5/02 , C07K9/00 , C07C103/52
CPC分类号： C07C243/00 , C07K5/0215 , C07K9/005 , C12R1/465 , A61K38/00
摘要： The invention relates to novel peptides and their pharmaceutically acceptable salts, particularly useful for pharmaceutical purposes such as in the therapeutic treatment of infectious diseases caused by pathogenic microorganisms. The compounds have the structure ##STR1## wherein R.sup.1 is hydrogen or acyl;R.sup.2 is carboxy or protected carboxy or a group of the formula: --COHN--R.sub.a.sup.2 wherein R.sub.a.sup.2 is carboxy (lower) alkyl or protected carboxy (lower) alkyl;R.sup.3 is carboxy, protected carboxy, lower alkyl, hydroxyphenyl, carbamoyl or a group of the formula: ##STR2## wherein R.sub.a.sup.3 is hydrogen, amino, protected amino or acylamino, R.sub.b.sup.3 is carboxy or protected carboxy;R.sup.p is carboxy, protected carboxy, carbamoyl, carboxy (lower) alkyl or protected carboxy (lower) alkyl;l is an integer 2,m is an integer 0 to 2 andn is an integer 1,provided that,whenR.sup.1 is hydrogen or acyl,R.sup.2 is carboxy, protected carboxy or a group of the formula: --CONHR.sub.a.sup.2 wherein R.sub.a.sup.2 is carboxy (lower) alkyl or protected carboxy (lower) alkyl,R.sup.p is carboxy, or protected carboxy, m is an integer 2, thenR.sup.3 is carbamoyl, lower alkyl or hydroxyphenyl or a group of the formula: ##STR3## wherein R.sub.a.sup.3 is hydrogen or acylamino and R.sub.b.sup.3 is carboxy or protected caboxy, andwhenR.sup.p is carbamoyl, thenR.sup.1 is acyl.
摘要翻译：本发明涉及新型肽及其药学上可接受的盐，特别可用于药物目的，例如由病原微生物引起的感染性疾病的治疗性治疗。这些化合物具有结构，其中R 1是氢或酰基; R2是羧基或保护的羧基或下式基团-COHN-Ra2，其中Ra2是羧基（低级）烷基或被保护的羧基（低级）烷基; R 3是羧基，保护的羧基，低级烷基，羟基苯基，氨基甲酰基或下式的基团：其中R 3a是氢，氨基，被保护的氨基或酰氨基，R 3b是羧基或被保护的羧基; Rp是羧基，保护的羧基，氨基甲酰基，羧基（低级）烷基或被保护的羧基（低级）烷基; l为整数2，m为整数0〜2，n为整数1，条件是当R 1为氢或酰基时，R 2为羧基，被保护的羧基或式-CONHRa 2基团，其中Ra 2为羧基（低级）烷基或受保护的羧基（低级）烷基，Rp是羧基或受保护的羧基，m是整数2，则R3是氨基甲酰基，低级烷基或羟基苯基或下式的基团：其中R 3a是氢或酰基氨基并且R 3b是羧基或被保护的环氧基，当Rp是氨基甲酰基时，则R1是酰基。

59. 发明授权

US4140654A Catalyst composition with support comprising titanium oxide and clay mineral for vapor phase reduction of nitrogen oxides 失效
标题翻译：含有氧化钛和粘土矿物的载体的催化剂组合物用于氮氧化物的气相还原
公开(公告)号：US4140654A
公开(公告)日：1979-02-20
申请号：US786825
申请日：1977-04-12
申请人： Toshihiro Yoshioka , Shikiho Itaya , Yusaku Arima , Hirokazu Tanaka
发明人： Toshihiro Yoshioka , Shikiho Itaya , Yusaku Arima , Hirokazu Tanaka
IPC分类号： B01D53/94 , B01J23/16 , B01J23/72 , B01J27/02 , B01J8/00 , B01J21/06 , B01J21/16
CPC分类号： B01J23/72 , B01D53/9418 , B01J23/16 , B01D2251/2062 , B01D2255/207 , B01D2255/9202
摘要： A catalyst composition for the vapor phase reduction of nitrogen oxides with ammonia, which consists essentially of a non-noble transition metal compound supported on a shaped carrier comprising a titanium oxide and a clay mineral having an average particle size of 0.1 to 100 microns. The shaped carrier preferably contains an additional component which is an inorganic fibrous material, silica hydrogel, silica sol, or a mixture of at least two of these. An exhaust gas containing nitrogen oxides is treated, with a high percent NO removal, by contacting it with the catalyst composition in the presence of ammonia gas at 200 to 600.degree. C.
摘要翻译：一种用氨蒸气还原氮氧化物的催化剂组合物，其主要由负载在包含二氧化钛和平均粒度为0.1至100微米的粘土矿物的成形载体上的非贵重过渡金属化合物组成。成形载体优选含有作为无机纤维材料，二氧化硅水凝胶，硅溶胶或其中至少两种的混合物的附加组分。通过在氨气存在下在200〜600℃下与催化剂组合物接触，处理含有氮氧化物的废气，除去NO除量高。

60. 发明授权

US09315372B2 Grease pump unit 有权
标题翻译：油脂泵单元
公开(公告)号：US09315372B2
公开(公告)日：2016-04-19
申请号：US14009704
申请日：2012-01-17
申请人： Hiroyuki Doi , Hirokazu Tanaka
发明人： Hiroyuki Doi , Hirokazu Tanaka
IPC分类号： B67D7/36 , B67D7/04 , F16N7/38 , F16N11/10 , F16N25/00
CPC分类号： B67D7/04 , F16N7/385 , F16N11/10 , F16N25/00 , Y10T137/2931
摘要： A grease pump unit has a metering valve 37 and a grease supplying device 50 in which a suction tube 16 on a pump device 11 extends through a follower plate 19 in a grease can 100, grease in the grease can 100 being sucked through the suction tube 16 and discharged through a discharge port 17 by activation of the pump device 11. Provided are a bubble dividing device 32 which supplies the grease discharged through the discharge port 17 through an supply pipe 24 to micronize bubbles in the grease and which supplies the grease through a supply pipe 36 to the metering valve 37, and a return pipe 47 which returns a portion of the grease not discharged through the metering valve 37 into the grease can 100 via the follower plate 19.
摘要翻译：油脂泵单元具有计量阀37和润滑脂供给装置50，其中泵装置11上的吸入管16通过润滑脂罐100中的从动板19延伸，润滑脂罐100中的润滑脂通过吸管并且通过泵装置11的激活通过排出口17排出。气泡分离装置32通过供给管24供给通过排出口17排出的油脂，以微粉化润滑脂中的气泡，并且通过向计量阀37供给的供给管36，以及通过从动板19使未经计量阀37排出的润滑脂的一部分返回到润滑脂罐100中的回流管47。

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