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    • 52. 发明授权
    • Respiration signal measurement apparatus, systems, and methods
    • 呼吸信号测量装置,系统和方法
    • US07101339B2
    • 2006-09-05
    • US10319794
    • 2002-12-13
    • Douglas R. DaumQingsheng ZhuAvram Scheiner
    • Douglas R. DaumQingsheng ZhuAvram Scheiner
    • A61B5/08
    • A61N1/36521
    • A cardiac rhythm management apparatus and system may include a first sensor to sense an atrial respiration signal, a second sensor to sense a ventricular respiration signal, and a measurement module capable of being communicatively coupled to the first and second sensors to monitor the atrial and ventricular respiration signals and to select a resulting signal as an indication of respiration. An article may cause a machine to implement a method which includes measuring a second signal responsive to a first signal, measuring a third signal responsive to a first signal, determining a respiration-to-cardiac ratio associated with each one of the second and third signals, and providing a resulting signal including a selected portion of a selected one of the second and third signals as an indication of respiration.
    • 心律管理装置和系统可以包括用于感测心房呼吸信号的第一传感器,用于感测心室呼吸信号的第二传感器,以及能够通信地耦合到第一和第二传感器以监测心房和心室的测量模块 呼吸信号,并选择一个结果信号作为呼吸指示。 物品可以使机器实现一种方法,其包括响应于第一信号测量第二信号,响应于第一信号测量第三信号,确定与第二和第三信号中的每一个相关联的呼吸心脏比 并且提供包括所选择的第二和第三信号中的一个的选定部分的结果信号作为呼吸的指示。
    • 59. 发明授权
    • Rate management during automatic capture verification
    • 自动捕获验证期间的费率管理
    • US06473649B1
    • 2002-10-29
    • US09470269
    • 1999-12-22
    • Mark GryzwaQingsheng Zhu
    • Mark GryzwaQingsheng Zhu
    • A61N137
    • A61N1/3712Y10S128/901
    • An implantable cardiac rhythm management device capable of automatically detecting intrinsic and evoked response of a patient's heart and suitable for use during capture verification. The device of the present invention may operate in an automatic capture verification mode, wherein an electrocardiogram signal of a patient's heart is received and used by the device to determine whether a stimulation pulse evokes a response by the patient's heart. The device suspends the automatic capture verification mode and/or adjust the detection threshold dependent upon detected and/or measured noise, a determined amplitude of evoked response, a determined modulation in the evoked response, or detected and/or measured artifact. Further, the sensing circuit of the rhythm management device of the present invention reduces afterpotentials that result due to delivery of the stimulation pulses.
    • 一种植入式心律管理装置,其能够自动检测患者心脏的内在和诱发反应并适于在捕获验证期间使用。 本发明的装置可以在自动捕获验证模式下操作,其中由装置接收并使用患者心脏的心电图信号,以确定刺激脉冲是否引起患者心脏的反应。 取决于检测到的和/或测量的噪声,所确定的诱发响应幅度,诱发响应中的确定调制,或检测到的和/或测量的伪影,该装置暂停自动捕获验证模式和/或调整检测阈值。 此外,本发明的节律管理装置的感测电路减少了由于刺激脉冲的传送而导致的后电位。
    • 60. 发明授权
    • Pseudo-fusion management during automatic capture verification
    • 自动捕获验证期间的伪融合管理
    • US06275731B1
    • 2001-08-14
    • US09474193
    • 1999-12-29
    • Qingsheng ZhuJungkuk KimArthur OliveJan-Pieter Heemels
    • Qingsheng ZhuJungkuk KimArthur OliveJan-Pieter Heemels
    • A61N1365
    • A61N1/3712
    • A method for reducing the affects of intrinsic detection latency in a cardiac rhythm management device, wherein said method is initiated immediately prior to delivering a stimulation pulse to the heart tissue. A coincidence of intrinsic and cardiac rhythm management initiated stimulus or the delivery of a stimulation pulse proximate the time of an intrinsic event due to intrinsic detection latency may results in delivery of unnecessary backup stimulus and/or imprecise determination of a pacing threshold. When stimulating the heart, the timing sequence for delivering a stimulation pulse typically depends upon the timing of a previous intrinsic or device initiated event. Further, the method of the present invention reduces the affects of intrinsic detection latency thereby facilitating improved detection of capture and determination of capture threshold for minimizing power consumption while assuring therapeutic efficacy.
    • 一种减轻心律管理装置中内在检测延迟的影响的方法,其中所述方法在将刺激脉冲传递到心脏组织之前立即开始。 由于内在的检测潜伏期,固有和心律管理发起的刺激或接近内在事件时间的刺激脉冲的传递的巧合可能导致递送不必要的备份刺激和/或不精确地确定起搏阈值。 当刺激心脏时,用于递送刺激脉冲的定时序列通常取决于先前的固有或设备启动事件的时序。 此外,本发明的方法减少了内在检测潜能的影响,从而有助于提高捕获捕获阈值的检测和捕获阈值的确定,以最大限度地降低功耗,同时确保治疗效果。