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51. 发明申请

US20070185199A1 Pharmaceutical formulations 审中-公开
标题翻译：药物制剂
公开(公告)号：US20070185199A1
公开(公告)日：2007-08-09
申请号：US11548960
申请日：2006-10-12
申请人： Tzuchi Ju , Claudia Davila , Yi Gao , Linda Gustavson , David LeBlond , Tong Zhu
发明人： Tzuchi Ju , Claudia Davila , Yi Gao , Linda Gustavson , David LeBlond , Tong Zhu
IPC分类号： A61K31/222
CPC分类号： A61K9/2077 , A61K9/1635 , A61K9/1652 , A61K9/2846 , A61K9/2866 , A61K31/192
摘要： The present invention relates to oral formulations comprising an active agent comprising at least one of 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid, salts of 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid or buffered 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid.
摘要翻译：本发明涉及包含含有2- [4-（4-氯苯甲酰基）苯氧基] -2-甲基 - 丙酸中的至少一种的活性剂，2- [4-（4-氯苯甲酰基）苯氧基] -2-甲基 - 丙酸或缓冲的2- [4-（4-氯苯甲酰基）苯氧基] -2-甲基 - 丙酸。

52. 发明申请

US20070148234A1 Pharmaceutical formulations 审中-公开
公开(公告)号：US20070148234A1
公开(公告)日：2007-06-28
申请号：US11548982
申请日：2006-10-12
申请人： Tzuchi Ju , Claudia Davila , Kevin Engh , Yi Gao , Linda Gustavson , Shyamala Jayaraman , David LeBlond , Dennis Lee , Tong Zhu
发明人： Tzuchi Ju , Claudia Davila , Kevin Engh , Yi Gao , Linda Gustavson , Shyamala Jayaraman , David LeBlond , Dennis Lee , Tong Zhu
IPC分类号： A61K9/20 , A61K31/192
CPC分类号： A61K9/2866 , A61K9/1623 , A61K9/1635 , A61K9/1652 , A61K9/2077 , A61K9/2846 , A61K31/192
摘要： The present invention relates to oral formulations comprising an active agent comprising at least one of 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid, salts of 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid or buffered 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid.

53. 发明授权

US06528700B1 Targeted manipulation of genes in plants 失效
标题翻译：植物中基因的靶向操作
公开(公告)号：US06528700B1
公开(公告)日：2003-03-04
申请号：US09193612
申请日：1998-11-17
申请人： Christopher L. Baszczynski , Benjamin A. Bowen , John H. Duesing , David J. Peterson , Laura A. Tagliani , Tong Zhu
发明人： Christopher L. Baszczynski , Benjamin A. Bowen , John H. Duesing , David J. Peterson , Laura A. Tagliani , Tong Zhu
IPC分类号： C12N1582
CPC分类号： C12N15/1137 , C12N15/102 , C12N15/8213 , C12N15/8274 , C12N2310/321 , C12N2310/53 , C12N2310/3521
摘要： Methods and compositions for altering a nucleotide sequence of interest in a plant is provided. The method involves introducing a chimeric oligonucleotide into a RNA residues with intervening DNA residues. The RNA blocks are homologous to a plant nucleotide sequence. The chimeric oligonucleotide is capable of folding to form a duplex oligonucleotide. The chimeric oligonucleotide is maintained within the nucleus of the plant whereby the alteration is introduced into the target sequences of the plant genome.
摘要翻译：提供了用于改变植物中感兴趣的核苷酸序列的方法和组合物。该方法包括将嵌合寡核苷酸引入具有中间DNA残基的RNA残基中。 RNA嵌段与植物核苷酸序列同源。嵌合寡核苷酸能折叠形成双链寡核苷酸。嵌合寡核苷酸保持在植物的细胞核内，从而将改变引入植物基因组的靶序列。

54. 发明申请

US20150141646A1 Drug-Conjugates, Conjugation Methods, and Uses Thereof 有权
标题翻译：药物缀合物，共轭方法及其用途
公开(公告)号：US20150141646A1
公开(公告)日：2015-05-21
申请号：US14401318
申请日：2013-05-14
申请人： Zhenwei Miao , Yufeng Hong , Tong Zhu
发明人： Zhenwei Miao , Yufeng Hong , Tong Zhu
IPC分类号： C07K5/06 , C07D207/09 , C07D403/12 , C07D277/593 , C07F5/02 , C07D207/08 , C07D401/12
CPC分类号： A61K47/6855 , A61K38/07 , A61K47/6803 , A61K47/6811 , A61K47/6849 , A61K47/6889 , C07D207/08 , C07D207/09 , C07D277/593 , C07D401/12 , C07D403/12 , C07F5/025 , C07K5/06008
摘要： In certain aspects, compounds and uses thereof are provided. In certain aspects, compound-conjugates and uses thereof are provided.
摘要翻译：在某些方面，提供了化合物及其用途。在某些方面，提供了化合物缀合物及其用途。

55. 发明申请

US20130053376A1 NOVEL TYROSINE KINASE INHIBITORS 有权
公开(公告)号：US20130053376A1
公开(公告)日：2013-02-28
申请号：US12922891
申请日：2009-03-18
申请人： Yahua Liu , Alexey Vyacheslavovich Anikin , Charles Chamchoumis Mikel , Douglas Eric McGrath , Goverdhan Reddy Vavilala , Jason Conrad Pickens , Aleksander Kadushkin , Luyong Jiang , Mohan Santhanam Thiruvazhi , Sergey Zozulya , Rajendran Vairagoundar , Tong Zhu , Alexander Chucholowski , Zheng Yan , Alisher Khasanov , Christina Gregor
发明人： Vlad Edward Gregor , Yahua Liu , Alexey Vyacheslavovich Anikin , Charles Chamchoumis Mikel , Douglas Eric McGrath , Goverdhan Reddy Vavilala , Jason Conrad Pickens , Aleksander Kadushkin , Luyong Jiang , Mohan Santhanam Thiruvazhi , Sergey Zozulya , Rajendran Vairagoundar , Tong Zhu , Alexander Chucholowski , Zheng Yan , Alisher Khasanov
IPC分类号： A61K31/4545 , C07D401/14 , A61K31/4439 , C07D413/14 , C12N9/99 , A61K31/541 , C07D405/14 , A61K31/5377 , A61P35/00 , C07D487/04 , C07D417/14
CPC分类号： C07D401/14 , A61K31/4439 , A61K31/4545 , C07D487/04
摘要： Provided are compounds of the formula (I): or a stereoisomer, tautomer, salt, hydrate or prodrug thereof that modulate tyrosine kinase activity, compositions comprising the compounds and methods of their use.

56. 发明申请

US20120216036A1 ENCRYPTION METHODS AND SYSTEMS 审中-公开
标题翻译：加密方法和系统
公开(公告)号：US20120216036A1
公开(公告)日：2012-08-23
申请号：US13400481
申请日：2012-02-20
申请人： Magued Barsoum , Tong Zhu
发明人： Magued Barsoum , Tong Zhu
IPC分类号： H04L9/00
CPC分类号： H04L63/0428 , H04L63/162
摘要： Systems and methods are described for securely transmitting data in a mesh network. The method includes: performing on a processor, assembling a header with a recipient address, wherein the recipient address designates an encryption endpoint; associating encrypted data with the header; and presenting a packet for transmittal on the mesh network, wherein the packet includes the header and the encrypted data.
摘要翻译：描述了在网状网络中安全地传输数据的系统和方法。该方法包括：在处理器上执行与接收者地址组合报头，其中接收方地址指定加密端点; 将加密数据与标题相关联; 以及在所述网状网络上呈现用于传送的分组，其中所述分组包括所述报头和所述加密数据。

57. 发明申请

US20120171262A1 PHARMACEUTICAL FORMULATIONS 审中-公开
标题翻译：药物制剂
公开(公告)号：US20120171262A1
公开(公告)日：2012-07-05
申请号：US13421551
申请日：2012-03-15
申请人： Tzuchi R. Ju , Claudia M. Davila , Yi Gao , Linda E. Gustavson , David LeBlond , Tong Zhu
发明人： Tzuchi R. Ju , Claudia M. Davila , Yi Gao , Linda E. Gustavson , David LeBlond , Tong Zhu
IPC分类号： A61K31/205 , A61K31/44 , A61K31/55 , A61K31/4545 , A61K31/4184 , A61K31/40 , A61K31/404 , A61K31/4439 , A61K31/549 , A61K31/506 , A61K31/585 , A61K31/366 , A61K31/47 , A61K31/785 , A61P7/00 , A61P9/00 , A61P3/00 , A61P9/12 , A61K9/00
CPC分类号： A61K31/205 , A61K9/00 , A61K9/1623 , A61K9/1635 , A61K9/1652 , A61K9/2009 , A61K9/2018 , A61K9/2027 , A61K9/2054 , A61K9/2077 , A61K9/2846 , A61K9/2866 , A61K9/4808 , A61K31/192 , A61K45/06
摘要： The present invention relates to oral formulations comprising an active agent comprising at least one of 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid, salts of 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid or buffered 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid.
摘要翻译：本发明涉及包含含有2- [4-（4-氯苯甲酰基）苯氧基] -2-甲基 - 丙酸中的至少一种的活性剂，2- [4-（4-氯苯甲酰基）苯氧基] -2-甲基 - 丙酸或缓冲的2- [4-（4-氯苯甲酰基）苯氧基] -2-甲基 - 丙酸。

58. 发明授权

US07853248B2 SMS spam control 有权
标题翻译：短信垃圾邮件控制
公开(公告)号：US07853248B2
公开(公告)日：2010-12-14
申请号：US11859539
申请日：2007-09-21
申请人： Rohini Harendra , Olga Volodymyrivna Gavrylyako , Tong Zhu , Kenneth Tsz Ho
发明人： Rohini Harendra , Olga Volodymyrivna Gavrylyako , Tong Zhu , Kenneth Tsz Ho
IPC分类号： H04M3/00
CPC分类号： H04L51/12 , H04L51/38
摘要： A system, apparatus, and method are directed towards managing abuse of text messages through controls on messages sent by an application to a mobile device (e.g., MT text messages). MT text messages sent from a defined application are intercepted by a Text Message SPAM Control Service (TMSCS). Various controls are determined for the sending application based on the application, level of user control on contents of the message, the user requesting the message to be sent (if any), and/or a destination address for the message. These controls may then be used in various combinations and/or various levels of constraint to determine whether to block transmission of the message to a destination mobile device. By monitoring messages from the application, abuse of the application may be minimized.
摘要翻译：系统，装置和方法旨在通过对由应用发送到移动设备的消息（例如，MT文本消息）的控制来管理文本消息的滥用。从定义的应用程序发送的MT文本消息被文本消息SPAM控制服务（TMSCS）拦截。基于应用，用户对消息内容的控制级别，请求发送消息的用户（如果有的话）和/或消息的目的地地址来确定针对发送应用的各种控制。然后可以以各种组合和/或各种限制级别来使用这些控制以确定是否阻止消息到目的地移动设备的传输。通过监视来自应用程序的消息，滥用应用程序可能会最小化。

59. 发明授权

US07734907B2 Methods and systems for redirecting data 有权
标题翻译：用于重定向数据的方法和系统
公开(公告)号：US07734907B2
公开(公告)日：2010-06-08
申请号：US10730222
申请日：2003-12-08
申请人： Tong Zhu
发明人： Tong Zhu
IPC分类号： H04L9/00
CPC分类号： H04L63/16 , H04L63/061
摘要： Systems and methods are disclosed for redirecting data. These systems and methods may include transmitting over a network an indication from a first node to a second node that a third node has failed. In addition, a first data may be reconfigured to be transmitted over the network between a fourth node and the first node after the indication has been received by the second node. The first data may be initially configured to be transmitted over the network between the second node and the third node. Furthermore, the disclosed systems and methods may include configuring the first node and the fourth node to send and receive the reconfigured first data as encrypted data via a first tunnel and configuring the second node and the third node to send and receive the first data as encrypted data via a second tunnel.
摘要翻译：公开了用于重定向数据的系统和方法。这些系统和方法可以包括通过网络从第一节点向第二节点发送第三节点已经失败的指示。此外，在由第二节点接收到指示之后，第一数据可以被重新配置为在第四节点和第一节点之间的网络上传输。第一数据可以被初始配置为通过网络在第二节点和第三节点之间传输。此外，所公开的系统和方法可以包括配置第一节点和第四节点经由第一隧道发送和接收作为加密数据的重新配置的第一数据，并且配置第二节点和第三节点以发送和接收加密的第一数据数据通过第二个隧道。

60. 发明授权

US07693902B2 Enabling clustered search processing via text messaging 有权
标题翻译：通过短信进行集群搜索处理
公开(公告)号：US07693902B2
公开(公告)日：2010-04-06
申请号：US11833173
申请日：2007-08-02
申请人： Ben Kim , Tong Zhu
发明人： Ben Kim , Tong Zhu
IPC分类号： G06F17/30
CPC分类号： G06F17/30867
摘要： Methods and apparatus for searching data, grouping search results into categories that are ordered according to search relevance, and reviewing the search results via text messaging. In one embodiment, a search term is submitted via a search request text message to a short code for a search service. The search service searches for content based on the search term and context data, such as location of a submitting client device. The search results are clustered into categories and ranked by relevance to the search term and context within each category. The categories are also ranked relative to each other. The most relevant search result from the most relevant category is transmitted in an initial result text message, which also includes instructions to access additional results via subsequent text messages. Each result text message also includes a link to a web page of categorized search results for display in a browser.
摘要翻译：用于搜索数据的方法和装置，将搜索结果分组成根据搜索相关性排序的类别，以及通过短信查看搜索结果。在一个实施例中，通过搜索请求文本消息将搜索项提交给搜索服务的短代码。搜索服务基于搜索项和上下文数据搜索内容，诸如提交客户端设备的位置。搜索结果被聚类成类别，并且与每个类别中的搜索词和上下文的相关性排列。这些类别也相对排列。来自最相关类别的最相关的搜索结果在初始结果文本消息中传输，其中还包括通过后续文本消息访问附加结果的指令。每个结果文本消息还包括到分类搜索结果的网页的链接以在浏览器中显示。

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